메뉴 건너뛰기




Volumn 219, Issue , 2014, Pages 281-292

Arrestin-mediated activation of p38 MAPK: Molecular mechanisms and behavioral consequences

Author keywords

Arrestin; Dynorphin; Kappa opioid receptor; p38 MAPK

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; DYNORPHIN; G PROTEIN COUPLED RECEPTOR KINASE 3; KAPPA OPIATE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; POTASSIUM CHANNEL; POTASSIUM CHANNEL KIR3; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3; ION CHANNEL; RETINA S ANTIGEN;

EID: 84958539903     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-41199-1_14     Document Type: Article
Times cited : (18)

References (53)
  • 2
    • 0033588094 scopus 로고    scopus 로고
    • Agonistdependent desensitization of the kappa opioid receptor by G protein receptor kinase and ?-arrestin
    • Appleyard SM, Celver J, Pineda V, Kovoor A, Wayman GA, Chavkin C (1999) Agonistdependent desensitization of the kappa opioid receptor by G protein receptor kinase and ?-arrestin. J Biol Chem 274:23802-23807
    • (1999) J Biol Chem , vol.274 , pp. 23802-23807
    • Appleyard, S.M.1    Celver, J.2    Pineda, V.3    Kovoor, A.4    Wayman, G.A.5    Chavkin, C.6
  • 3
    • 84861740178 scopus 로고    scopus 로고
    • Silent scaffolds: Inhibition of c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant
    • Breitman M, Kook S, Gimenez LE, Lizama BN, Palazzo MC, Gurevich EV, Gurevich VV (2012) Silent scaffolds: inhibition of c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant. J Biol Chem 287:19653-19664
    • (2012) J Biol Chem , vol.287 , pp. 19653-19664
    • Breitman, M.1    Kook, S.2    Gimenez, L.E.3    Lizama, B.N.4    Palazzo, M.C.5    Gurevich, E.V.6    Gurevich, V.V.7
  • 4
    • 77951855896 scopus 로고    scopus 로고
    • Kinase cascades and ligand-directed signaling at the kappa opioid receptor
    • Bruchas MR, Chavkin C (2010) Kinase cascades and ligand-directed signaling at the kappa opioid receptor. Psychopharmacology (Berl) 210:137-147
    • (2010) Psychopharmacology (Berl) , vol.210 , pp. 137-147
    • Bruchas, M.R.1    Chavkin, C.2
  • 5
    • 33745832645 scopus 로고    scopus 로고
    • Kappa opioid receptor activation of p38MAPK is GRK3-and arrestin-dependent in neurons and astrocytes
    • BruchasMR,Macey TA, Lowe JD,ChavkinC (2006)Kappa opioid receptor activation of p38MAPK is GRK3-and arrestin-dependent in neurons and astrocytes. J Biol Chem 281:18081-18089
    • (2006) J Biol Chem , vol.281 , pp. 18081-18089
    • Bruchas, M.R.1    MacEy, T.A.2    Lowe, J.D.3    Chavkin, C.4
  • 6
    • 35548997505 scopus 로고    scopus 로고
    • Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria
    • Bruchas MR, Land BB, Aita M, Xu M, Barot SK, Li S, Chavkin C (2007a) Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria. J Neurosci 27:11614-11623
    • (2007) J Neurosci , vol.27 , pp. 11614-11623
    • Bruchas, M.R.1    Land, B.B.2    Aita, M.3    Xu, M.4    Barot, S.K.5    Li, S.6    Chavkin, C.7
  • 7
    • 35649027979 scopus 로고    scopus 로고
    • Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase
    • Bruchas MR, Yang T, Schreiber S, Defino M, Kwan SC, Li S, Chavkin C (2007b) Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase. J Biol Chem 282:29803-29811
    • (2007) J Biol Chem , vol.282 , pp. 29803-29811
    • Bruchas, M.R.1    Yang, T.2    Schreiber, S.3    Defino, M.4    Kwan, S.C.5    Li, S.6    Chavkin, C.7
  • 8
    • 54049091662 scopus 로고    scopus 로고
    • Repeated swim-stress induces kappa opioid-mediated activation of ERK1/2 MAPK
    • Bruchas MR, Xu M, Chavkin C (2008) Repeated swim-stress induces kappa opioid-mediated activation of ERK1/2 MAPK. Neuroreport 19(14):1417-1422
    • (2008) Neuroreport , vol.19 , Issue.14 , pp. 1417-1422
    • Bruchas, M.R.1    Xu, M.2    Chavkin, C.3
  • 9
    • 77954039086 scopus 로고    scopus 로고
    • CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior
    • Bruchas MR, Land BB, Lemos JC, Chavkin C (2009) CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior. PLoS One 4 (12):e8528
    • (2009) PLoS One , vol.4 , Issue.12
    • Bruchas, M.R.1    Land, B.B.2    Lemos, J.C.3    Chavkin, C.4
  • 11
    • 0034009390 scopus 로고    scopus 로고
    • Signal transduction Hanging on a scaffold
    • Burack WR, Shaw AS (2000) Signal transduction. Hanging on a scaffold. Curr Opin Cell Biol 12:211-216
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 211-216
    • Burack, W.R.1    Shaw, A.S.2
  • 12
    • 0020029345 scopus 로고
    • Dynorphin is a specific endogenous ligand of the kappa opioid receptor
    • Chavkin C, James IF, Goldstein A (1982) Dynorphin is a specific endogenous ligand of the kappa opioid receptor. Science 215:413-415
    • (1982) Science , vol.215 , pp. 413-415
    • Chavkin, C.1    James, I.F.2    Goldstein, A.3
  • 13
    • 78649666302 scopus 로고    scopus 로고
    • The therapeutic potential of kappa opioids for treatment of pain and addiction
    • Chavkin C (2011) The therapeutic potential of kappa opioids for treatment of pain and addiction. Neuropsychopharmacology 36:369-370
    • (2011) Neuropsychopharmacology , vol.36 , pp. 369-370
    • Chavkin, C.1
  • 14
    • 0021889437 scopus 로고
    • Mu and kappa opioids inhibit transmitter release by different mechanisms
    • Cherubini E, North RA (1985) Mu and kappa opioids inhibit transmitter release by different mechanisms. Proc Natl Acad Sci USA 82:1860-1863
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1860-1863
    • Cherubini, E.1    North, R.A.2
  • 15
    • 70450267365 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Kir3 following kappa opioid receptor activation of p38-MAPK causes heterologous desensitization
    • Clayton CC, Xu M, Chavkin C (2009) Tyrosine phosphorylation of Kir3 following kappa opioid receptor activation of p38-MAPK causes heterologous desensitization. J Biol Chem 284:31872-31881
    • (2009) J Biol Chem , vol.284 , pp. 31872-31881
    • Clayton, C.C.1    Xu, M.2    Chavkin, C.3
  • 16
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
    • Daaka Y, Luttrell LM, Lefkowitz RJ (1997) Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 390:88-91
    • (1997) Nature , vol.390 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 17
    • 84857476249 scopus 로고    scopus 로고
    • Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons
    • Dang VC, Christie MJ (2012) Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons. Br J Pharmacol 165:1704-1716
    • (2012) Br J Pharmacol , vol.165 , pp. 1704-1716
    • Dang, V.C.1    Christie, M.J.2
  • 19
    • 73949084919 scopus 로고    scopus 로고
    • A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation
    • 1ra1
    • Gesty P. D, Flannery P, Yuan L, Corsino L, Spurney R, Lefkowitz RJ, Luttrell LM (2009) A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med 1:1ra1
    • (2009) Sci Transl Med , pp. 1
    • Gesty, P.D.1    Flannery, P.2    Yuan, L.3    Corsino, L.4    Spurney, R.5    Lefkowitz, R.J.6    Luttrell, L.M.7
  • 20
    • 0028879630 scopus 로고
    • Opioid receptors and the regulation of ion conductances
    • Grudt TJ, Williams JT (1995) Opioid receptors and the regulation of ion conductances. Rev Neurosci 6:279-286
    • (1995) Rev Neurosci , vol.6 , pp. 279-286
    • Grudt, T.J.1    Williams, J.T.2
  • 23
    • 0037031844 scopus 로고    scopus 로고
    • N-terminal tyrosine residues within the potassium channel Kir3 modulate GTPase activity of Galphai
    • Ippolito DL, Temkin PA, Rogalski SL, Chavkin C (2002) N-terminal tyrosine residues within the potassium channel Kir3 modulate GTPase activity of Galphai. J Biol Chem 277:32692-32696
    • (2002) J Biol Chem , vol.277 , pp. 32692-32696
    • Ippolito, D.L.1    Temkin, P.A.2    Rogalski, S.L.3    Chavkin, C.4
  • 24
    • 29244443656 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of K (ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress
    • Ippolito DL, Xu M, Bruchas MR, Wickman K, Chavkin C (2005) Tyrosine phosphorylation of K (ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress. J Biol Chem 280:41683-41693
    • (2005) J Biol Chem , vol.280 , pp. 41683-41693
    • Ippolito, D.L.1    Xu, M.2    Bruchas, M.R.3    Wickman, K.4    Chavkin, C.5
  • 25
    • 38349031157 scopus 로고    scopus 로고
    • The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system
    • Land BB, Bruchas MR, Lemos JC, Xu M, Melief EJ, Chavkin C (2008) The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system. J Neurosci 28:407-414
    • (2008) J Neurosci , vol.28 , pp. 407-414
    • Land, B.B.1    Bruchas, M.R.2    Lemos, J.C.3    Xu, M.4    Melief, E.J.5    Chavkin, C.6
  • 26
    • 84865739173 scopus 로고    scopus 로고
    • Repeated stress exposure dysregulates kappa opioid receptor signaling in the dorsal raphe through a p38? MAPK dependent mechanism
    • Lemos JC, Roth CA, Messinger DI, Gill HK, Phillips PEM, Chavkin C (2012) Repeated stress exposure dysregulates kappa opioid receptor signaling in the dorsal raphe through a p38? MAPK dependent mechanism. J Neurosci 32:12325-12336
    • (2012) J Neurosci , vol.32 , pp. 12325-12336
    • Lemos, J.C.1    Roth, C.A.2    Messinger, D.I.3    Gill, H.K.4    Phillips, P.E.M.5    Chavkin, C.6
  • 27
    • 0036140923 scopus 로고    scopus 로고
    • Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2- (1-pyrrolidiny)-cyclohexyl]benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells
    • Li J, Li JG, Chen C, Zhang F, Liu-Chen LY (2002) Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl] benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells. Mol Pharmacol 61:73-84
    • (2002) Mol Pharmacol , vol.61 , pp. 73-84
    • Li, J.1    Li, J.G.2    Chen, C.3    Zhang, F.4    Liu-Chen, L.Y.5
  • 30
    • 0141557543 scopus 로고    scopus 로고
    • Phosphorylation of a carboxy-terminal serine within the kappa opioid receptor produces desensitization and internalization
    • McLaughlin JP, Xu M, Mackie K, Chavkin C (2003) Phosphorylation of a carboxy-terminal serine within the kappa opioid receptor produces desensitization and internalization. J Biol Chem 278:34631-34640
    • (2003) J Biol Chem , vol.278 , pp. 34631-34640
    • McLaughlin, J.P.1    Xu, M.2    MacKie, K.3    Chavkin, C.4
  • 31
    • 33645027285 scopus 로고    scopus 로고
    • Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning
    • McLaughlin JP, Land BB, Li S, Pintar JE, Chavkin C (2006) Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning. Neuropsychopharmacology 31:787-794
    • (2006) Neuropsychopharmacology , vol.31 , pp. 787-794
    • McLaughlin, J.P.1    Land, B.B.2    Li, S.3    Pintar, J.E.4    Chavkin, C.5
  • 33
    • 77954923289 scopus 로고    scopus 로고
    • Ligand-directed Jun kinase activation disrupts opioid receptor signaling
    • Melief EJ, Miyatake M, Bruchas MR, Chavkin C (2010) Ligand-directed Jun kinase activation disrupts opioid receptor signaling. Proc Natl Acad Sci USA 107:11608-11613
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11608-11613
    • Melief, E.J.1    Miyatake, M.2    Bruchas, M.R.3    Chavkin, C.4
  • 34
    • 0037821781 scopus 로고    scopus 로고
    • G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR
    • Miller WE, Houtz DA, Nelson CD, Kolattukudy PE, Lefkowitz RJ (2003) G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR. J Biol Chem 278:21663-21671
    • (2003) J Biol Chem , vol.278 , pp. 21663-21671
    • Miller, W.E.1    Houtz, D.A.2    Nelson, C.D.3    Kolattukudy, P.E.4    Lefkowitz, R.J.5
  • 37
    • 0022494591 scopus 로고
    • Psychotomimesis mediated by kappa opiate receptors
    • Pfeiffer A, Brantl V, Herz A, Emrich HM (1986) Psychotomimesis mediated by kappa opiate receptors. Science 233:774-776
    • (1986) Science , vol.233 , pp. 774-776
    • Pfeiffer, A.1    Brantl, V.2    Herz, A.3    Emrich, H.M.4
  • 38
    • 84864540082 scopus 로고    scopus 로고
    • 6'-Guanidinonaltrindole (6'-GNTI) is a G protein-biased opioid receptor agonist that inhibits arrestin recruitment
    • Rives ML, Rossillo M, Liu-Chen LY, Javitch JA (2012) 6'- Guanidinonaltrindole (6'-GNTI) is a G protein-biased opioid receptor agonist that inhibits arrestin recruitment. J Biol Chem 287:27050-27054
    • (2012) J Biol Chem , vol.287 , pp. 27050-27054
    • Rives, M.L.1    Rossillo, M.2    Liu-Chen, L.Y.3    Javitch, J.A.4
  • 39
    • 12144279565 scopus 로고    scopus 로고
    • A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: Evidence for distinct cellular mechanisms involved in transporter surface expression
    • Samuvel DJ, Jayanthi LD, Bhat NR, Ramamoorthy S (2005) A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression. J Neurosci 25:29-41
    • (2005) J Neurosci , vol.25 , pp. 29-41
    • Samuvel, D.J.1    Jayanthi, L.D.2    Bhat, N.R.3    Ramamoorthy, S.4
  • 42
    • 0022822520 scopus 로고
    • Differential effects of mu and kappa opioid systems on motivational processes
    • Shippenberg TS, Herz A (1986) Differential effects of mu and kappa opioid systems on motivational processes. NIDA Res Monogr 75:563-66
    • (1986) NIDA Res Monogr , vol.75 , pp. 563-566
    • Shippenberg, T.S.1    Herz, A.2
  • 43
    • 0030339216 scopus 로고    scopus 로고
    • Endogenous opioid regulation of hippocampal function
    • Simmons ML, Chavkin C (1996) Endogenous opioid regulation of hippocampal function. Int Rev Neurobiol 39:145-196
    • (1996) Int Rev Neurobiol , vol.39 , pp. 145-196
    • Simmons, M.L.1    Chavkin, C.2
  • 44
    • 0037147145 scopus 로고    scopus 로고
    • Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
    • Sun Y, Cheng Z, Ma L, Pei G (2002) Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem 277:49212-49219
    • (2002) J Biol Chem , vol.277 , pp. 49212-49219
    • Sun, Y.1    Cheng, Z.2    Ma, L.3    Pei, G.4
  • 48
    • 0021745419 scopus 로고
    • Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons
    • Werz MA, Macdonald RL (1984) Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons. Neuropeptides 5:253-256
    • (1984) Neuropeptides , vol.5 , pp. 253-256
    • Werz, M.A.1    MacDonald, R.L.2
  • 50
    • 33847795830 scopus 로고    scopus 로고
    • Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 Mitogen-Activated Protein Kinase
    • Xu M, Bruchas MR, Ippolito DL, Gendron L, Chavkin C (2007) Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 Mitogen-Activated Protein Kinase. J Neurosci 27:2570-2581
    • (2007) J Neurosci , vol.27 , pp. 2570-2581
    • Xu, M.1    Bruchas, M.R.2    Ippolito, D.L.3    Gendron, L.4    Chavkin, C.5
  • 51
    • 84865117109 scopus 로고    scopus 로고
    • Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways
    • Yang X, Zhou G, Ren T, Li H, Zhang Y, Yin D, Qian H, Li Q (2012) ?-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways. Apoptosis 17:1019-1026
    • (2012) Apoptosis , vol.17 , pp. 1019-1026
    • Yang, X.1    Zhou, G.2    Ren, T.3    Li, H.4    Zhang, Y.5    Yin, D.6    Qian, H.7    Li, Q.8
  • 52
    • 2442650231 scopus 로고    scopus 로고
    • Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation
    • Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD (2004) Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation. Mol Pharmacol 65:1462-1474
    • (2004) Mol Pharmacol , vol.65 , pp. 1462-1474
    • Zhu, C.B.1    Hewlett, W.A.2    Feoktistov, I.3    Biaggioni, I.4    Blakely, R.D.5
  • 53
    • 18144373742 scopus 로고    scopus 로고
    • P38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process
    • Zhu CB, Carneiro AM, Dostmann WR, Hewlett WA, Blakely RD (2005) p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process. J Biol Chem 280:15649-15658
    • (2005) J Biol Chem , vol.280 , pp. 15649-15658
    • Zhu, C.B.1    Carneiro, A.M.2    Dostmann, W.R.3    Hewlett, W.A.4    Blakely, R.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.