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1
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84873531706
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Guidelines and quality measures: do they improve outcomes of patients with community-acquired pneumonia?
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PID: 23398866
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Johnstone J, Mandell L. Guidelines and quality measures: do they improve outcomes of patients with community-acquired pneumonia? Infect Dis Clin North Am. 2013;27(1):71–86.
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(2013)
Infect Dis Clin North Am
, vol.27
, Issue.1
, pp. 71-86
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Johnstone, J.1
Mandell, L.2
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2
-
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84893609243
-
Clinical practice. Community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC2cXisFaktLc%3D, PID: 24499212, Major importance: It is an overview of CAP that help us to decide the antibiotic therapy, the extent of testing to determine the cause of pneumonia, and the appropriate location of treatment (home, inpatient floor, or ICU)
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Wunderink RG, Waterer GW. Clinical practice. Community-acquired pneumonia. N Engl J Med. 2014;370(6):543–51. Major importance: It is an overview of CAP that help us to decide the antibiotic therapy, the extent of testing to determine the cause of pneumonia, and the appropriate location of treatment (home, inpatient floor, or ICU).
-
(2014)
N Engl J Med
, vol.370
, Issue.6
, pp. 543-551
-
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Wunderink, R.G.1
Waterer, G.W.2
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3
-
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84879996414
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Severe community-acquired pneumonia
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PID: 23830654, This article show us the epidemiology of severe CAP. Up to 22 % of patients with CAP require ICU admission, with 44 to 83 % requiring mechanical ventilation and up to 50 % presenting with concomitant septic shock
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Sligl WI, Marrie TJ. Severe community-acquired pneumonia. Crit Care Clin. 2013;29(3):563–601. This article show us the epidemiology of severe CAP. Up to 22 % of patients with CAP require ICU admission, with 44 to 83 % requiring mechanical ventilation and up to 50 % presenting with concomitant septic shock.
-
(2013)
Crit Care Clin
, vol.29
, Issue.3
, pp. 563-601
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Sligl, W.I.1
Marrie, T.J.2
-
4
-
-
84904767954
-
Contrasting inflammatory responses in severe and non-severe community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC2cXhtFShtrzJ, PID: 24557760, Major importance: this study compared systemic and local cytokine profiles in patients with severe versus non-severe CAP. Results indicate that patients with severe CAP fail to mount a local pro-inflammatory response but exhibit instead a more substantial systemic inflammatory response
-
Fernandez-Botran R, Uriarte SM, Arnold FW, et al. Contrasting inflammatory responses in severe and non-severe community-acquired pneumonia. Inflammation. 2014;37(4):1158–66. Major importance: this study compared systemic and local cytokine profiles in patients with severe versus non-severe CAP. Results indicate that patients with severe CAP fail to mount a local pro-inflammatory response but exhibit instead a more substantial systemic inflammatory response.
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(2014)
Inflammation
, vol.37
, Issue.4
, pp. 1158-1166
-
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Fernandez-Botran, R.1
Uriarte, S.M.2
Arnold, F.W.3
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5
-
-
84862002394
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Cytokine activation patterns and biomarkers are influenced by microorganisms in community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC38XhtFSit7zK, PID: 22194589, Major importance: There is a different inflammatory patterns elicited by different microorganisms. Recognizing these patterns may facilitate a broader understanding of host inflammatory response to microorganisms
-
Menendez R, Sahuquillo-Arce JM, Reyes S, et al. Cytokine activation patterns and biomarkers are influenced by microorganisms in community-acquired pneumonia. Chest. 2012;141(6):1537–45. Major importance: There is a different inflammatory patterns elicited by different microorganisms. Recognizing these patterns may facilitate a broader understanding of host inflammatory response to microorganisms.
-
(2012)
Chest
, vol.141
, Issue.6
, pp. 1537-1545
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Menendez, R.1
Sahuquillo-Arce, J.M.2
Reyes, S.3
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6
-
-
84878803283
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Local and systemic cytokine profiles in nonsevere and severe community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC3sXhtV2murzN, PID: 23258791, Local and systemic cytokine profiles in nonsevere and severe community-acquired pneumonia
-
Paats MS, Bergen IM, Hanselaar WE, et al. Local and systemic cytokine profiles in nonsevere and severe community-acquired pneumonia. Eur Respir J. 2013;41(6):1378–85. Local and systemic cytokine profiles in nonsevere and severe community-acquired pneumonia.
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(2013)
Eur Respir J
, vol.41
, Issue.6
, pp. 1378-1385
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Paats, M.S.1
Bergen, I.M.2
Hanselaar, W.E.3
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7
-
-
84907045288
-
Immunomodulatory adjuvant therapy in severe community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC2cXhsFejt7rK, PID: 24898699, Immunomodulatory adjuvant therapy in severe community-acquired pneumonia
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Morton B, Pennington SH, Gordon SB. Immunomodulatory adjuvant therapy in severe community-acquired pneumonia. Expert Rev Respir Med. 2014;8(5):587–96. Immunomodulatory adjuvant therapy in severe community-acquired pneumonia.
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(2014)
Expert Rev Respir Med
, vol.8
, Issue.5
, pp. 587-596
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Morton, B.1
Pennington, S.H.2
Gordon, S.B.3
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8
-
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84901468713
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Community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC2cXitVSlurzN, PID: 25337751, This is a Major importance article; it is a review of CAP, since the epidemiology data to diagnostic methods and treatment
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Musher DM, Thorner AR. Community-acquired pneumonia. N Engl J Med. 2014;371(17):1619–28. This is a Major importance article; it is a review of CAP, since the epidemiology data to diagnostic methods and treatment.
-
(2014)
N Engl J Med
, vol.371
, Issue.17
, pp. 1619-1628
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Musher, D.M.1
Thorner, A.R.2
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9
-
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84938405426
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Community-acquired pneumonia requiring hospitalization among U.S. adults
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COI: 1:CAS:528:DC%2BC2MXhtlyktLvK, PID: 26172429, This is a very important article. It show that the incidence of community-acquired pneumonia requiring hospitalization was highest among the oldest adults. No pathogen was detected in the majority of patients and respiratory viruses were detected more frequently than bacteria
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Jain S, Self WH, Wunderink RG, et al. Community-acquired pneumonia requiring hospitalization among U.S. adults. N Engl J Med. 2015;373(5):415–27. This is a very important article. It show that the incidence of community-acquired pneumonia requiring hospitalization was highest among the oldest adults. No pathogen was detected in the majority of patients and respiratory viruses were detected more frequently than bacteria.
-
(2015)
N Engl J Med
, vol.373
, Issue.5
, pp. 415-427
-
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Jain, S.1
Self, W.H.2
Wunderink, R.G.3
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10
-
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84924066710
-
Viral etiology of community-acquired pneumonia among adolescents and adults with mild or moderate severity and its relation to age and severity
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PID: 25812108, Major importance, it is about recent epidemiological data of patients from Beijing, China, from 2010 to 2012
-
Qu JX, Gu L, Pu ZH, et al. Viral etiology of community-acquired pneumonia among adolescents and adults with mild or moderate severity and its relation to age and severity. BMC Infect Dis. 2015;15:89. Major importance, it is about recent epidemiological data of patients from Beijing, China, from 2010 to 2012.
-
(2015)
BMC Infect Dis
, vol.15
, pp. 89
-
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Qu, J.X.1
Gu, L.2
Pu, Z.H.3
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11
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84944152654
-
Community-acquired pneumonia: an overview
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PID: 26224210
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Mandell LA. Community-acquired pneumonia: an overview. Postgrad Med. 2015;127(6):607–15.
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(2015)
Postgrad Med
, vol.127
, Issue.6
, pp. 607-615
-
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Mandell, L.A.1
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12
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84873554933
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Clinical scoring tools: which is best to predict clinical response and long-term outcomes?
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PID: 23398864
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Wiemken T, Kelley R, Ramirez J. Clinical scoring tools: which is best to predict clinical response and long-term outcomes? Infect Dis Clin North Am. 2013;27(1):33–48.
-
(2013)
Infect Dis Clin North Am
, vol.27
, Issue.1
, pp. 33-48
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-
Wiemken, T.1
Kelley, R.2
Ramirez, J.3
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13
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33847155159
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Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
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COI: 1:CAS:528:DC%2BD2sXjtVWrs74%3D, PID: 17278083, It is a very important article, these are the last CAP guidelines from the IDSA/ATS
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Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44 Suppl 2:S27–72. It is a very important article, these are the last CAP guidelines from the IDSA/ATS.
-
(2007)
Clin Infect Dis
, vol.44
, pp. S27-S72
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Mandell, L.A.1
Wunderink, R.G.2
Anzueto, A.3
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14
-
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84873339299
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Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012
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PID: 23353941
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Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580–637.
-
(2013)
Crit Care Med
, vol.41
, Issue.2
, pp. 580-637
-
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Dellinger, R.P.1
Levy, M.M.2
Rhodes, A.3
-
15
-
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84873538809
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What is the role of antimicrobial stewardship in improving outcomes of patients with CAP?
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PID: 23398876
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Nussenblatt V, Avdic E, Cosgrove S. What is the role of antimicrobial stewardship in improving outcomes of patients with CAP? Infect Dis Clin North Am. 2013;27(1):211–28.
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(2013)
Infect Dis Clin North Am
, vol.27
, Issue.1
, pp. 211-228
-
-
Nussenblatt, V.1
Avdic, E.2
Cosgrove, S.3
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16
-
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84921988670
-
Antibiotics for community-acquired pneumonia in adult outpatients
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PID: 25300166
-
Pakhale S, Mulpuru S, Verheij TJ, Kochen MM, Rohde GG, Bjerre LM. Antibiotics for community-acquired pneumonia in adult outpatients. Cochrane Database Syst Rev. 2014;10:CD002109.
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(2014)
Cochrane Database Syst Rev
, vol.10
, pp. CD002109
-
-
Pakhale, S.1
Mulpuru, S.2
Verheij, T.J.3
Kochen, M.M.4
Rohde, G.G.5
Bjerre, L.M.6
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17
-
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84873534405
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Does empirical therapy with a fluoroquinolone or the combination of a beta-lactam plus a macrolide result in better outcomes for patients admitted to the general ward?
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PID: 23398869
-
Ruhe J, Mildvan D. Does empirical therapy with a fluoroquinolone or the combination of a beta-lactam plus a macrolide result in better outcomes for patients admitted to the general ward? Infect Dis Clin North Am. 2013;27(1):115–32.
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(2013)
Infect Dis Clin North Am
, vol.27
, Issue.1
, pp. 115-132
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Ruhe, J.1
Mildvan, D.2
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18
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84943819492
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The association between the Th-17 immune response and pulmonary complications in a trauma ICU population
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COI: 1:CAS:528:DC%2BC2MXhsV2lsL%2FN, PID: 26364992
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Holloway TL, Rani M, Cap AP, Stewart RM, Schwacha MG. The association between the Th-17 immune response and pulmonary complications in a trauma ICU population. Cytokine. 2015;76(2):328–33.
-
(2015)
Cytokine
, vol.76
, Issue.2
, pp. 328-333
-
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Holloway, T.L.1
Rani, M.2
Cap, A.P.3
Stewart, R.M.4
Schwacha, M.G.5
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19
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84937520595
-
-
Hsieh YC, Chi H, Chang KY, et al. Increase in fitness of Streptococcus pneumoniae is associated with the severity of necrotizing pneumonia. Pediatr Infect Dis J. 2015;34(5):499–505. Major Importance: a pediatric population study demonstrated that IL-8 was associated with the severity of lung necrosis in CAP due to S. pneumoniae
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Hsieh YC, Chi H, Chang KY, et al. Increase in fitness of Streptococcus pneumoniae is associated with the severity of necrotizing pneumonia. Pediatr Infect Dis J. 2015;34(5):499–505. Major Importance: a pediatric population study demonstrated that IL-8 was associated with the severity of lung necrosis in CAP due toS. pneumoniae.
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-
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20
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84929991972
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IL-6 and TNF-alpha serum levels are associated with early death in community-acquired pneumonia patients
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COI: 1:CAS:528:DC%2BC2MXhsFKmtrvK, PID: 25714883, It is very important article because in a Brazilian population with CAP, the IL-6 levels showed a good association with severity scores, such as APACHE II and CURB-65
-
Bacci MR, Leme RC, Zing NP, et al. IL-6 and TNF-alpha serum levels are associated with early death in community-acquired pneumonia patients. Braz J Med Biol Res. 2015;48(5):427–32. It is very important article because in a Brazilian population with CAP, the IL-6 levels showed a good association with severity scores, such as APACHE II and CURB-65.
-
(2015)
Braz J Med Biol Res
, vol.48
, Issue.5
, pp. 427-432
-
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Bacci, M.R.1
Leme, R.C.2
Zing, N.P.3
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21
-
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84925050187
-
Predicting treatment failure in patients with community acquired pneumonia: a case–control study
-
PID: 24996572
-
Martin-Loeches I, Valles X, Menendez R, et al. Predicting treatment failure in patients with community acquired pneumonia: a case–control study. Respir Res. 2014;15:75.
-
(2014)
Respir Res
, vol.15
, pp. 75
-
-
Martin-Loeches, I.1
Valles, X.2
Menendez, R.3
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22
-
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84897849284
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IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC2cXmtVajt7w%3D, PID: 24725540, The findings of this article may indicate that CAP susceptibility is a multifactorial disease and other molecules or genes may be involved
-
Zidan HE, Elbehedy RM, Azab SF. IL6-174 G/C gene polymorphism and its relation to serum IL6 in Egyptian children with community-acquired pneumonia. Cytokine. 2014;67(2):60–4. The findings of this article may indicate that CAP susceptibility is a multifactorial disease and other molecules or genes may be involved.
-
(2014)
Cytokine
, vol.67
, Issue.2
, pp. 60-64
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Zidan, H.E.1
Elbehedy, R.M.2
Azab, S.F.3
-
23
-
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84876284684
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T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia
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PID: 23315492, Important article. Reported that patients with CAP showed high levels of Th17 subset, IL-17A and IL-22 cells in BAL and peripheral blood, which suggests a protective role
-
Paats MS, Bergen IM, Hanselaar WE, et al. T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia. Thorax. 2013;68(5):468–74. Important article. Reported that patients with CAP showed high levels of Th17 subset, IL-17A and IL-22 cells in BAL and peripheral blood, which suggests a protective role.
-
(2013)
Thorax
, vol.68
, Issue.5
, pp. 468-474
-
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Paats, M.S.1
Bergen, I.M.2
Hanselaar, W.E.3
-
24
-
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58149296036
-
Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens
-
COI: 1:CAS:528:DC%2BD1MXhsVCitr4%3D, PID: 19125888
-
Curtis MM, Way SS. Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology. 2009;126(2):177–85.
-
(2009)
Immunology
, vol.126
, Issue.2
, pp. 177-185
-
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Curtis, M.M.1
Way, S.S.2
-
25
-
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84898631378
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Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV
-
COI: 1:CAS:528:DC%2BC2cXmtVCnu7c%3D, PID: 24721575
-
Stacey MA, Marsden M, Pham NT, et al. Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV. Cell Host Microbe. 2014;15(4):471–83.
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(2014)
Cell Host Microbe
, vol.15
, Issue.4
, pp. 471-483
-
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Stacey, M.A.1
Marsden, M.2
Pham, N.T.3
-
26
-
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84917671792
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The effect of age on the systemic inflammatory response in patients with community-acquired pneumonia
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PID: 24930498, Important article. The results of this study suggest that elderly patients show a reduction in their systemic inflammatory response on admission for CAP
-
van Vught LA, Endeman H, Meijvis SC, et al. The effect of age on the systemic inflammatory response in patients with community-acquired pneumonia. Clin Microbiol Infect. 2014;20(11):1183–8. Important article. The results of this study suggest that elderly patients show a reduction in their systemic inflammatory response on admission for CAP.
-
(2014)
Clin Microbiol Infect
, vol.20
, Issue.11
, pp. 1183-1188
-
-
van Vught, L.A.1
Endeman, H.2
Meijvis, S.C.3
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28
-
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34250165460
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Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury
-
COI: 1:CAS:528:DC%2BD2sXmtVKnsbk%3D, PID: 17548653
-
Petty JM, Sueblinvong V, Lenox CC, et al. Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury. J Immunol. 2007;178(12):8148–57.
-
(2007)
J Immunol
, vol.178
, Issue.12
, pp. 8148-8157
-
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Petty, J.M.1
Sueblinvong, V.2
Lenox, C.C.3
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29
-
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84900528114
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Diverse macrophage populations mediate acute lung inflammation and resolution
-
COI: 1:CAS:528:DC%2BC2cXns1Gktbo%3D, PID: 24508730
-
Aggarwal NR, King LS, D’Alessio FR. Diverse macrophage populations mediate acute lung inflammation and resolution. Am J Physiol Lung Cell Mol Physiol. 2014;306(8):L709–25.
-
(2014)
Am J Physiol Lung Cell Mol Physiol
, vol.306
, Issue.8
, pp. L709-L725
-
-
Aggarwal, N.R.1
King, L.S.2
D’Alessio, F.R.3
-
30
-
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84908374828
-
Elevated plasma stromal-cell-derived factor-1 protein levels correlate with severity in patients with community-acquired pneumonia
-
PID: 25371597, Important reference. It showed that stromal-cell-derived factor-1 (SDF-1) has a positive correlation with CURB-65, APACHE II, and especially the PSI score in patients with CAP
-
Tsai PK, Hsieh MJ, Wang HL, Chou MC, Yang SF, Yeh CB. Elevated plasma stromal-cell-derived factor-1 protein levels correlate with severity in patients with community-acquired pneumonia. Dis Markers. 2014;2014:829706. Important reference. It showed that stromal-cell-derived factor-1 (SDF-1) has a positive correlation with CURB-65, APACHE II, and especially the PSI score in patients with CAP.
-
(2014)
Dis Markers
, vol.2014
, pp. 829706
-
-
Tsai, P.K.1
Hsieh, M.J.2
Wang, H.L.3
Chou, M.C.4
Yang, S.F.5
Yeh, C.B.6
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31
-
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84899002650
-
Matrix metalloproteinases in pneumonia
-
COI: 1:CAS:528:DC%2BC2cXovVKgs74%3D, PID: 24721641
-
Chiang TY, Tsao SM, Yeh CB, Yang SF. Matrix metalloproteinases in pneumonia. Clin Chim Acta. 2014;433:272–7.
-
(2014)
Clin Chim Acta
, vol.433
, pp. 272-277
-
-
Chiang, T.Y.1
Tsao, S.M.2
Yeh, C.B.3
Yang, S.F.4
-
32
-
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84929000067
-
Influenza virus-induced lung injury: pathogenesis and implications for treatment
-
COI: 1:CAS:528:DC%2BC2MXhtVGju7nL, PID: 25792631, Major importance: this article is an overview of influenza virus and potential molecular treatment
-
Herold S, Becker C, Ridge KM, Budinger GR. Influenza virus-induced lung injury: pathogenesis and implications for treatment. Eur Respir J. 2015;45(5):1463–78. Major importance: this article is an overview of influenza virus and potential molecular treatment.
-
(2015)
Eur Respir J
, vol.45
, Issue.5
, pp. 1463-1478
-
-
Herold, S.1
Becker, C.2
Ridge, K.M.3
Budinger, G.R.4
-
33
-
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84874538463
-
The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies
-
COI: 1:CAS:528:DC%2BC3sXjvV2gsrg%3D, PID: 23468921
-
Davey Jr RT, Lynfield R, Dwyer DE, et al. The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies. PLoS One. 2013;8(2):e57121.
-
(2013)
PLoS One
, vol.8
, Issue.2
, pp. e57121
-
-
Davey, R.T.1
Lynfield, R.2
Dwyer, D.E.3
-
34
-
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84857781518
-
IL-17 response mediates acute lung injury induced by the 2009 pandemic influenza A (H1N1) virus
-
COI: 1:CAS:528:DC%2BC38Xjt1Wjurs%3D, PID: 22025253, Important article: it showed the correlation between IL-17 and acute lung injury
-
Li C, Yang P, Sun Y, et al. IL-17 response mediates acute lung injury induced by the 2009 pandemic influenza A (H1N1) virus. Cell Res. 2012;22(3):528–38. Important article: it showed the correlation between IL-17 and acute lung injury.
-
(2012)
Cell Res
, vol.22
, Issue.3
, pp. 528-538
-
-
Li, C.1
Yang, P.2
Sun, Y.3
-
35
-
-
84920540951
-
CD206+ cell number differentiates influenza A (H1N1)pdm09 from seasonal influenza A virus in fatal cases
-
PID: 25614715, Important article: this study showed that the inflammatory cytokine storm is involved in the immunopathogenesis of influenza A pneumonia, and regulatory mechanisms were not enough to control the inflammatory response
-
Rodriguez-Ramirez HG, Salinas-Carmona MC, Barboza-Quintana O, et al. CD206+ cell number differentiates influenza A (H1N1)pdm09 from seasonal influenza A virus in fatal cases. Mediators Inflamm. 2014;2014:921054. Important article: this study showed that the inflammatory cytokine storm is involved in the immunopathogenesis of influenza A pneumonia, and regulatory mechanisms were not enough to control the inflammatory response.
-
(2014)
Mediators Inflamm
, vol.2014
, pp. 921054
-
-
Rodriguez-Ramirez, H.G.1
Salinas-Carmona, M.C.2
Barboza-Quintana, O.3
-
36
-
-
84896973126
-
TGF-beta activation and function in immunity
-
COI: 1:CAS:528:DC%2BC2cXovVemtrs%3D, PID: 24313777
-
Travis MA, Sheppard D. TGF-beta activation and function in immunity. Annu Rev Immunol. 2014;32:51–82.
-
(2014)
Annu Rev Immunol
, vol.32
, pp. 51-82
-
-
Travis, M.A.1
Sheppard, D.2
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37
-
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84930853841
-
TGF-beta blood levels distinguish between influenza A (H1N1)pdm09 virus sepsis and sepsis due to other forms of community-acquired pneumonia
-
COI: 1:CAS:528:DC%2BC2MXpsFOhsLc%3D, PID: 25923384, Important article: this study found a negative correlation between the best score (SOFA) to evaluate influenza and TGF-beta
-
Rendon-Ramirez EJ, Ortiz-Stern A, Martinez-Mejia C, et al. TGF-beta blood levels distinguish between influenza A (H1N1)pdm09 virus sepsis and sepsis due to other forms of community-acquired pneumonia. Viral Immunol. 2015;28(5):248–54. Important article: this study found a negative correlation between the best score (SOFA) to evaluate influenza and TGF-beta.
-
(2015)
Viral Immunol
, vol.28
, Issue.5
, pp. 248-254
-
-
Rendon-Ramirez, E.J.1
Ortiz-Stern, A.2
Martinez-Mejia, C.3
-
38
-
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84929460224
-
Host response to respiratory syncytial virus infection
-
PID: 25887611
-
Arruvito L, Raiden S, Geffner J. Host response to respiratory syncytial virus infection. Curr Opin Infect Dis. 2015;28(3):259–66.
-
(2015)
Curr Opin Infect Dis
, vol.28
, Issue.3
, pp. 259-266
-
-
Arruvito, L.1
Raiden, S.2
Geffner, J.3
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39
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84863538415
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Respiratory syncytial virus infection and immunity
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COI: 1:CAS:528:DC%2BC38XpvVehtb0%3D, PID: 22290692
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Gonzalez PA, Bueno SM, Carreno LJ, Riedel CA, Kalergis AM. Respiratory syncytial virus infection and immunity. Rev Med Virol. 2012;22(4):230–44.
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(2012)
Rev Med Virol
, vol.22
, Issue.4
, pp. 230-244
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Gonzalez, P.A.1
Bueno, S.M.2
Carreno, L.J.3
Riedel, C.A.4
Kalergis, A.M.5
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40
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84919875844
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Epidemiological characteristics and immune status of children with respiratory syncytial virus
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COI: 1:CAS:528:DC%2BC2cXitFWlsL%2FP, PID: 25123681
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Ye Q, Shao WX, Shang SQ, Pan YX, Shen HQ, Chen XJ. Epidemiological characteristics and immune status of children with respiratory syncytial virus. J Med Virol. 2015;87(2):323–9.
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(2015)
J Med Virol
, vol.87
, Issue.2
, pp. 323-329
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Ye, Q.1
Shao, W.X.2
Shang, S.Q.3
Pan, Y.X.4
Shen, H.Q.5
Chen, X.J.6
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41
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84898704244
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Prediction of prognosis by markers in community-acquired pneumonia
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COI: 1:CAS:528:DC%2BC3sXhsVyrurzM, PID: 24053273, Important article. It talks about several nonspecific non-cytokines biomarkers that we can use together with the severity pneumoniae scores
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Viasus D, Simonetti A, Garcia-Vidal C, Carratala J. Prediction of prognosis by markers in community-acquired pneumonia. Expert Rev Anti Infect Ther. 2013;11(9):917–29. Important article. It talks about several nonspecific non-cytokines biomarkers that we can use together with the severity pneumoniae scores.
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(2013)
Expert Rev Anti Infect Ther
, vol.11
, Issue.9
, pp. 917-929
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Viasus, D.1
Simonetti, A.2
Garcia-Vidal, C.3
Carratala, J.4
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42
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84958547726
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Procalcitonin kinetics in the first 72 hours predicts 30-day mortality in severely ill septic patients admitted to an intermediate care unit
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PID: 26251686
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Pieralli F, Vannucchi V, Mancini A, et al. Procalcitonin kinetics in the first 72 hours predicts 30-day mortality in severely ill septic patients admitted to an intermediate care unit. J Clin Med Res. 2015;7(9):706–13.
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(2015)
J Clin Med Res
, vol.7
, Issue.9
, pp. 706-713
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Pieralli, F.1
Vannucchi, V.2
Mancini, A.3
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43
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84898735972
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Predictive values of semi-quantitative procalcitonin test and common biomarkers for the clinical outcomes of community-acquired pneumonia
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PID: 24170911
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Ugajin M, Yamaki K, Hirasawa N, Yagi T. Predictive values of semi-quantitative procalcitonin test and common biomarkers for the clinical outcomes of community-acquired pneumonia. Respir Care. 2014;59(4):564–73.
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(2014)
Respir Care
, vol.59
, Issue.4
, pp. 564-573
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Ugajin, M.1
Yamaki, K.2
Hirasawa, N.3
Yagi, T.4
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44
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84942895101
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Soluble forms and ligands of the receptor for advanced glycation end-products in patients with acute respiratory distress syndrome: an observational prospective study
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PID: 26274928
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Jabaudon M, Blondonnet R, Roszyk L, et al. Soluble forms and ligands of the receptor for advanced glycation end-products in patients with acute respiratory distress syndrome: an observational prospective study. PLoS One. 2015;10(8):e0135857.
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(2015)
PLoS One
, vol.10
, Issue.8
, pp. e0135857
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Jabaudon, M.1
Blondonnet, R.2
Roszyk, L.3
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45
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84855998850
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Soluble RAGE as a severity marker in community acquired pneumonia associated sepsis
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PID: 22264245, Important article: an association between elevated sRAGE and fatal outcomes suggests that it may have an independent causal effect in CAP
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Narvaez-Rivera RM, Rendon A, Salinas-Carmona MC, Rosas-Taraco AG. Soluble RAGE as a severity marker in community acquired pneumonia associated sepsis. BMC Infect Dis. 2012;12:15. Important article: an association between elevated sRAGE and fatal outcomes suggests that it may have an independent causal effect in CAP.
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(2012)
BMC Infect Dis
, vol.12
, pp. 15
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Narvaez-Rivera, R.M.1
Rendon, A.2
Salinas-Carmona, M.C.3
Rosas-Taraco, A.G.4
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46
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84886284120
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IgM levels in plasma predict outcome in severe pandemic influenza
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COI: 1:CAS:528:DC%2BC3sXhsFCitbvI, PID: 24076102
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Justel M, Socias L, Almansa R, et al. IgM levels in plasma predict outcome in severe pandemic influenza. J Clin Virol. 2013;58(3):564–7.
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(2013)
J Clin Virol
, vol.58
, Issue.3
, pp. 564-567
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Justel, M.1
Socias, L.2
Almansa, R.3
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47
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84923125114
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Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial
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COI: 1:CAS:528:DC%2BC2MXkt1Sitr8%3D, PID: 25688779, Major importance: systemic corticosteroids have anti-inflammatory effects that may attenuate the local and systemic inflammatory process observed in CAP. Corticosteroids reduced the risk of treatment failure, but in-hospital mortality was not different
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Torres A, Sibila O, Ferrer M, et al. Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial. JAMA. 2015;313(7):677–86. Major importance: systemic corticosteroids have anti-inflammatory effects that may attenuate the local and systemic inflammatory process observed in CAP. Corticosteroids reduced the risk of treatment failure, but in-hospital mortality was not different.
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(2015)
JAMA
, vol.313
, Issue.7
, pp. 677-686
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Torres, A.1
Sibila, O.2
Ferrer, M.3
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48
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84868087224
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Corticosteroids in the treatment of community-acquired pneumonia in adults: a meta-analysis
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COI: 1:CAS:528:DC%2BC38Xhs1KisLvN, PID: 23112872, Major importance: this is a meta-analysis that did not find a benefit with the inclusion of corticosteroids in the treatment of CAP in adults, but it was very heterogeneous and not restricted to severe CAP
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Nie W, Zhang Y, Cheng J, Xiu Q. Corticosteroids in the treatment of community-acquired pneumonia in adults: a meta-analysis. PLoS One. 2012;7(10):e47926. Major importance: this is a meta-analysis that did not find a benefit with the inclusion of corticosteroids in the treatment of CAP in adults, but it was very heterogeneous and not restricted to severe CAP.
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(2012)
PLoS One
, vol.7
, Issue.10
, pp. e47926
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Nie, W.1
Zhang, Y.2
Cheng, J.3
Xiu, Q.4
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49
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84928423838
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Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial
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COI: 1:CAS:528:DC%2BC2MXhtVOltbs%3D, PID: 25608756, Major importance: this randomized multicenter study compared seven days of prednisone with a placebo in adult patients hospitalized with CAP and concluded that prednisone shortens time to clinical stability without an increase in complications
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Blum CA, Nigro N, Briel M, et al. Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet. 2015;385(9977):1511–8. Major importance: this randomized multicenter study compared seven days of prednisone with a placebo in adult patients hospitalized with CAP and concluded that prednisone shortens time to clinical stability without an increase in complications.
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(2015)
Lancet
, vol.385
, Issue.9977
, pp. 1511-1518
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Blum, C.A.1
Nigro, N.2
Briel, M.3
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50
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84904541031
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Inhaled corticosteroids and systemic inflammatory response in community-acquired pneumonia: a prospective clinical study
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PID: 24909304
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Ferrer M, Torres A, Martinez R, et al. Inhaled corticosteroids and systemic inflammatory response in community-acquired pneumonia: a prospective clinical study. Respirology. 2014;19(6):929–35.
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(2014)
Respirology
, vol.19
, Issue.6
, pp. 929-935
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Ferrer, M.1
Torres, A.2
Martinez, R.3
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51
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84856960076
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Immunomodulatory effects of macrolides during community-acquired pneumonia: a literature review
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COI: 1:CAS:528:DC%2BC38Xit1Ogtrc%3D, PID: 22190609
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Kovaleva A, Remmelts HH, Rijkers GT, Hoepelman AI, Biesma DH, Oosterheert JJ. Immunomodulatory effects of macrolides during community-acquired pneumonia: a literature review. J Antimicrob Chemother. 2012;67(3):530–40.
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(2012)
J Antimicrob Chemother
, vol.67
, Issue.3
, pp. 530-540
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Kovaleva, A.1
Remmelts, H.H.2
Rijkers, G.T.3
Hoepelman, A.I.4
Biesma, D.H.5
Oosterheert, J.J.6
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52
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84940446806
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Fluoroquinolones or macrolides alone versus combined with beta-lactams for adults with community-acquired pneumonia: systematic review and meta-analysis
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COI: 1:CAS:528:DC%2BC2MXhtVWgt77L, PID: 26092096
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Raz-Pasteur A, Shasha D, Paul M. Fluoroquinolones or macrolides alone versus combined with beta-lactams for adults with community-acquired pneumonia: systematic review and meta-analysis. Int J Antimicrob Agents. 2015;46(3):242–8.
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(2015)
Int J Antimicrob Agents
, vol.46
, Issue.3
, pp. 242-248
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Raz-Pasteur, A.1
Shasha, D.2
Paul, M.3
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53
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84893313755
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Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis
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COI: 1:CAS:528:DC%2BC2cXhtFyhtLc%3D, PID: 24158175, Important article: this is a systematic review and meta-analysis that evaluated macrolide use and mortality and found a statistically significant lower risk of mortality compared with non-macrolide but the heterogeneity among the studies was substantial
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Sligl WI, Asadi L, Eurich DT, Tjosvold L, Marrie TJ, Majumdar SR. Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis. Crit Care Med. 2014;42(2):420–32. Important article: this is a systematic review and meta-analysis that evaluated macrolide use and mortality and found a statistically significant lower risk of mortality compared with non-macrolide but the heterogeneity among the studies was substantial.
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(2014)
Crit Care Med
, vol.42
, Issue.2
, pp. 420-432
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Sligl, W.I.1
Asadi, L.2
Eurich, D.T.3
Tjosvold, L.4
Marrie, T.J.5
Majumdar, S.R.6
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54
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84898422647
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Efficacy of combination therapy with oseltamivir phosphate and azithromycin for influenza: a multicenter, open-label, randomized study
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PID: 24632748
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Kakeya H, Seki M, Izumikawa K, et al. Efficacy of combination therapy with oseltamivir phosphate and azithromycin for influenza: a multicenter, open-label, randomized study. PLoS One. 2014;9(3):e91293.
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(2014)
PLoS One
, vol.9
, Issue.3
, pp. e91293
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Kakeya, H.1
Seki, M.2
Izumikawa, K.3
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55
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84906790072
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Statins role in the prevention and treatment of sepsis
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COI: 1:CAS:528:DC%2BC2cXosFantbg%3D, PID: 24794878
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Dobesh PP, Olsen KM. Statins role in the prevention and treatment of sepsis. Pharmacol Res. 2014;88:31–40.
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(2014)
Pharmacol Res
, vol.88
, pp. 31-40
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Dobesh, P.P.1
Olsen, K.M.2
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56
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84872253001
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The role of statins in prevention and treatment of community acquired pneumonia: a systematic review and meta-analysis
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COI: 1:CAS:528:DC%2BC3sXhtFamtrw%3D, PID: 23349694
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Khan AR, Riaz M, Bin Abdulhak AA, et al. The role of statins in prevention and treatment of community acquired pneumonia: a systematic review and meta-analysis. PLoS One. 2013;8(1):e52929.
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(2013)
PLoS One
, vol.8
, Issue.1
, pp. e52929
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Khan, A.R.1
Riaz, M.2
Bin Abdulhak, A.A.3
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57
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84901759539
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Rosuvastatin for sepsis-associated acute respiratory distress syndrome
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Important article: this randomized study showed no mortality benefit and higher degree of hepatic and renal dysfunction
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National Heart L, Blood Institute ACTN, Truwit JD, et al. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med. 2014;370(23):2191–200. Important article: this randomized study showed no mortality benefit and higher degree of hepatic and renal dysfunction.
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(2014)
N Engl J Med
, vol.370
, Issue.23
, pp. 2191-2200
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National Heart, L.1
Blood Institute, A.C.T.N.2
Truwit, J.D.3
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58
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84961289143
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Linezolid has unique immunomodulatory effects in post-influenza community acquired MRSA pneumonia
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PID: 25635685
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Bhan U, Podsiad AB, Kovach MA, Ballinger MN, Keshamouni V, Standiford TJ. Linezolid has unique immunomodulatory effects in post-influenza community acquired MRSA pneumonia. PLoS One. 2015;10(1):e0114574.
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(2015)
PLoS One
, vol.10
, Issue.1
, pp. e0114574
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Bhan, U.1
Podsiad, A.B.2
Kovach, M.A.3
Ballinger, M.N.4
Keshamouni, V.5
Standiford, T.J.6
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