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Volumn 42, Issue 2, 2014, Pages 420-432

Macrolides and mortality in critically Ill patients with community-acquired pneumonia: A systematic review and meta-analysis

Author keywords

Community Acquired Pneumonia; Critical Care; Intensive Care; Macrolide; Mortality; Systematic Review

Indexed keywords

ANTIINFECTIVE AGENT; MACROLIDE;

EID: 84893313755     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182a66b9b     Document Type: Article
Times cited : (142)

References (54)
  • 1
    • 77950344427 scopus 로고    scopus 로고
    • Burden of community-acquired pneumonia in North American adults
    • File TM Jr, Marrie TJ: Burden of community-acquired pneumonia in North American adults. Postgrad Med 2010; 122:130-141
    • (2010) Postgrad Med , vol.122 , pp. 130-141
    • File Jr., T.M.1    Marrie, T.J.2
  • 3
    • 0031693610 scopus 로고    scopus 로고
    • The cost of treating community-acquired pneumonia
    • Niederman MS, McCombs JS, Unger AN, et al: The cost of treating community-acquired pneumonia. Clin Ther 1998; 20:820-837
    • (1998) Clin Ther , vol.20 , pp. 820-837
    • Niederman, M.S.1    McCombs, J.S.2    Unger, A.N.3
  • 4
    • 0343092060 scopus 로고    scopus 로고
    • Epidemiology of community-acquired pneumonia in adults: A population-based study
    • Almirall J, Bolíbar I, Vidal J, et al: Epidemiology of community-acquired pneumonia in adults: A population-based study. Eur Respir J 2000; 15:757-763
    • (2000) Eur Respir J , vol.15 , pp. 757-763
    • Almirall, J.1    Bolíbar, I.2    Vidal, J.3
  • 5
    • 84879996414 scopus 로고    scopus 로고
    • Severe community-acquired pneumonia
    • Sligl WI, Marrie TJ: Severe community-acquired pneumonia. Crit Care Clin 2013; 29:563-601
    • (2013) Crit Care Clin , vol.29 , pp. 563-601
    • Sligl, W.I.1    Marrie, T.J.2
  • 6
    • 15044339741 scopus 로고    scopus 로고
    • Immunomodulatory effects of antimicrobials in the therapy of respiratory tract infections
    • Parnham MJ: Immunomodulatory effects of antimicrobials in the therapy of respiratory tract infections. Curr Opin Infect Dis 2005; 18:125-131
    • (2005) Curr Opin Infect Dis , vol.18 , pp. 125-131
    • Parnham, M.J.1
  • 7
    • 53849142125 scopus 로고    scopus 로고
    • Immunomodulatory therapies for sepsis: Unexpected effects with macrolides
    • Giamarellos-Bourboulis EJ: Immunomodulatory therapies for sepsis: Unexpected effects with macrolides. Int J Antimicrob Agents 2008; 32(Suppl 1):S39-S43
    • (2008) Int J Antimicrob Agents , vol.32 , Issue.SUPPL. 1 , pp. 39-43
    • Giamarellos-Bourboulis, E.J.1
  • 8
    • 38348998987 scopus 로고    scopus 로고
    • Clarithromycin targets neutrophilic airway inflammation in refractory asthma
    • Simpson JL, Powell H, Boyle MJ, et al: Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med 2008; 177:148-155
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 148-155
    • Simpson, J.L.1    Powell, H.2    Boyle, M.J.3
  • 9
    • 80052157895 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations of COPD
    • COPD Clinical Research Network
    • Albert RK, Connett J, Bailey WC, et al; COPD Clinical Research Network: Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011; 365:689-698
    • (2011) N Engl J Med , vol.365 , pp. 689-698
    • Albert, R.K.1    Connett, J.2    Bailey, W.C.3
  • 10
    • 3543117815 scopus 로고    scopus 로고
    • Macrolide activities beyond their antimicrobial effects: Macrolides in diffuse panbronchiolitis and cystic fibrosis
    • Schultz MJ: Macrolide activities beyond their antimicrobial effects: Macrolides in diffuse panbronchiolitis and cystic fibrosis. J Antimicrob Chemother 2004; 54:21-28
    • (2004) J Antimicrob Chemother , vol.54 , pp. 21-28
    • Schultz, M.J.1
  • 11
    • 4544244010 scopus 로고    scopus 로고
    • Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia
    • International Pneumococcal Study Group
    • Baddour LM, Yu VL, Klugman KP, et al; International Pneumococcal Study Group: Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia. Am J Respir Crit Care Med 2004; 170:440-444
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 440-444
    • Baddour, L.M.1    Yu, V.L.2    Kp, K.3
  • 12
    • 77951209165 scopus 로고    scopus 로고
    • Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia
    • Martin-Loeches I, Lisboa T, Rodriguez A, et al: Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia. Intensive Care Med 2010; 36:612-620
    • (2010) Intensive Care Med , vol.36 , pp. 612-620
    • Martin-Loeches, I.1    Lisboa, T.2    Rodriguez, A.3
  • 13
    • 58849166805 scopus 로고    scopus 로고
    • Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia
    • Restrepo MI, Mortensen EM, Waterer GW, et al: Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia. Eur Respir J 2009; 33:153-159
    • (2009) Eur Respir J , vol.33 , pp. 153-159
    • Restrepo, M.I.1    Mortensen, E.M.2    Waterer, G.W.3
  • 14
    • 34249304464 scopus 로고    scopus 로고
    • Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
    • CAPUCI Study Group
    • Rodríguez A, Mendia A, Sirvent JM, et al; CAPUCI Study Group: Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock. Crit Care Med 2007; 35:1493-1498
    • (2007) Crit Care Med , vol.35 , pp. 1493-1498
    • Rodríguez, A.1    Mendia, A.2    Sirvent, J.M.3
  • 15
    • 42549119145 scopus 로고    scopus 로고
    • Effect of clarithromycin in patients with sepsis and ventilator- associated pneumonia
    • Giamarellos-Bourboulis EJ, Pechère JC, Routsi C, et al: Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia. Clin Infect Dis 2008; 46:1157-1164
    • (2008) Clin Infect Dis , vol.46 , pp. 1157-1164
    • Giamarellos-Bourboulis, E.J.1    Pechère, J.C.2    Routsi, C.3
  • 16
    • 84863933351 scopus 로고    scopus 로고
    • Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: A systematic review and meta-analysis
    • Asadi L, Sligl WI, Eurich DT, et al: Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: A systematic review and meta-analysis. Clin Infect Dis 2012; 55:371-380
    • (2012) Clin Infect Dis , vol.55 , pp. 371-380
    • Asadi, L.1    Sligl, W.I.2    Eurich, D.T.3
  • 17
    • 84861076083 scopus 로고    scopus 로고
    • Azithromycin and the risk of cardiovascular death
    • Ray WA, Murray KT, Hall K, et al: Azithromycin and the risk of cardiovascular death. N Engl J Med 2012; 366:1881-1890
    • (2012) N Engl J Med , vol.366 , pp. 1881-1890
    • Ray, W.A.1    Murray, K.T.2    Hall, K.3
  • 18
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: A proposal for reporting
    • Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group
    • Stroup DF, Berlin JA, Morton SC, et al: Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000; 283:2008-2012
    • (2000) JAMA , vol.283 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3
  • 19
    • 33646253414 scopus 로고    scopus 로고
    • How to identify randomized controlled trials in medline: Ten years on
    • Glanville JM, Lefebvre C, Miles JN, et al: How to identify randomized controlled trials in MEDLINE: Ten years on. J Med Libr Assoc 2006; 94:130-136
    • (2006) J Med Libr Assoc , vol.94 , pp. 130-136
    • Glanville, J.M.1    Lefebvre, C.2    Miles, J.N.3
  • 22
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, et al: Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-634
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3
  • 23
    • 33847155159 scopus 로고    scopus 로고
    • Infectious diseases society of america/american thoracic society consensus guidelines on the management of community-acquired pneumonia in adults
    • Infectious Diseases Society of America; American Thoracic Society
    • Mandell LA, Wunderink RG, Anzueto A, et al; Infectious Diseases Society of America; American Thoracic Society: Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007; 44(Suppl 2):S27-S72
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2 , pp. 27-72
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 24
    • 84879207411 scopus 로고    scopus 로고
    • Comparative safety and effectiveness of metformin in patients with diabetes mellitus and heart failure: Systematic review of observational studies involving 34,000 patients
    • Eurich DT, Weir DL, Majumdar SR, et al: Comparative safety and effectiveness of metformin in patients with diabetes mellitus and heart failure: Systematic review of observational studies involving 34,000 patients. Circ Heart Fail 2013; 6:395-402
    • (2013) Circ Heart Fail , vol.6 , pp. 395-402
    • Eurich, D.T.1    Weir, D.L.2    Majumdar, S.R.3
  • 25
    • 33751039945 scopus 로고    scopus 로고
    • Impact of initial antibiotic choice on mortality from pneumococcal pneumonia
    • Pneumococcal Pneumonia in Spain Study Group
    • Aspa J, Rajas O, Rodriguez De Castro F, et al; Pneumococcal Pneumonia in Spain Study Group: Impact of initial antibiotic choice on mortality from pneumococcal pneumonia. Eur Respir J 2006; 27:1010-1019
    • (2006) Eur Respir J , vol.27 , pp. 1010-1019
    • Aspa, J.1    Rajas, O.2    Rodriguez De Castro, F.3
  • 26
    • 58149260516 scopus 로고    scopus 로고
    • Initial antibiotic selection and patient outcomes: Observations from the national pneumonia project
    • Bratzler DW, Ma A, Nsa W: Initial antibiotic selection and patient outcomes: Observations from the National Pneumonia Project. Clin Infect Dis 2008; 47(Suppl 3):S193-S201
    • (2008) Clin Infect Dis , vol.47 , Issue.SUPPL. 3 , pp. 193-201
    • Bratzler, D.W.1    Ma, A.2    Nsa, W.3
  • 27
    • 33745901636 scopus 로고    scopus 로고
    • Evaluation of clinical practice in patients admitted with community-acquired pneumonia over a 4-year period
    • Capelastegui A, España PP, Quintana JM, et al: [Evaluation of clinical practice in patients admitted with community-acquired pneumonia over a 4-year period]. Arch Bronconeumol 2006; 42:283-289
    • (2006) Arch Bronconeumol , vol.42 , pp. 283-289
    • Capelastegui, A.1    España, P.P.2    Quintana, J.M.3
  • 28
    • 43249097833 scopus 로고    scopus 로고
    • The etiology of community-acquired pneumonia in australia: Why penicillin plus doxycycline or a macrolide is the most appropriate therapy
    • Australian CAP Study Collaboration
    • Charles PG, Whitby M, Fuller AJ, et al; Australian CAP Study Collaboration: The etiology of community-acquired pneumonia in Australia: Why penicillin plus doxycycline or a macrolide is the most appropriate therapy. Clin Infect Dis 2008; 46:1513-1521
    • (2008) Clin Infect Dis , vol.46 , pp. 1513-1521
    • Charles, P.G.1    Whitby, M.2    Fuller, A.J.3
  • 29
    • 80052646910 scopus 로고    scopus 로고
    • Community-acquired polymicrobial pneumonia in the intensive care unit: Aetiology and prognosis
    • Cillóniz C, Ewig S, Ferrer M, et al: Community-acquired polymicrobial pneumonia in the intensive care unit: Aetiology and prognosis. Crit Care 2011; 15:R209
    • (2011) Crit Care , vol.15 , pp. 209
    • Cillóniz, C.1    Ewig, S.2    Ferrer, M.3
  • 30
    • 58849141687 scopus 로고    scopus 로고
    • Adherence to guidelines empirical antibiotic recommendations and community-acquired pneumonia outcome
    • Dambrava PG, Torres A, Vallès X, et al: Adherence to guidelines empirical antibiotic recommendations and community-acquired pneumonia outcome. Eur Respir J 2008; 32:892-901
    • (2008) Eur Respir J , vol.32 , pp. 892-901
    • Dambrava, P.G.1    Torres, A.2    Vallès, X.3
  • 31
    • 79958810134 scopus 로고    scopus 로고
    • Impact of guideline-consistent therapy on outcome of patients with healthcare-associated and community-acquired pneumonia
    • Grenier C, Pépin J, Nault V, et al: Impact of guideline-consistent therapy on outcome of patients with healthcare-associated and community-acquired pneumonia. J Antimicrob Chemother 2011; 66:1617-1624
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1617-1624
    • Grenier, C.1    Pépin, J.2    Nault, V.3
  • 32
    • 70349168472 scopus 로고    scopus 로고
    • Validation of the infectious diseases society of america/american thoracic society criteria to predict severe community-acquired pneumonia caused by Streptococcus pneumoniae
    • Kontou P, Kuti JL, Nicolau DP: Validation of the Infectious Diseases Society of America/American Thoracic Society criteria to predict severe community-acquired pneumonia caused by Streptococcus pneumoniae. Am J Emerg Med 2009; 27:968-974
    • (2009) Am J Emerg Med , vol.27 , pp. 968-974
    • Kontou, P.1    Kuti, J.L.2    Nicolau, D.P.3
  • 33
    • 84861806287 scopus 로고    scopus 로고
    • Antibiotic strategy in severe community-acquired pneumococcal pneumonia
    • Le Bris-Tomczak A, Bedos JP, Billon C, et al: Antibiotic strategy in severe community-acquired pneumococcal pneumonia. Med Mal Infect 2012; 42:226-234
    • (2012) Med Mal Infect , vol.42 , pp. 226-234
    • Le Bris-Tomczak, A.1    Bedos, J.P.2    Billon, C.3
  • 34
    • 1942475175 scopus 로고    scopus 로고
    • Inpatient care of communityacquired pneumonia: The effect of antimicrobial guidelines on clinical outcomes and drug costs in Canadian teaching hospitals
    • Marras TK, Jamieson L, Chan CK: Inpatient care of communityacquired pneumonia: The effect of antimicrobial guidelines on clinical outcomes and drug costs in Canadian teaching hospitals. Can Respir J 2004; 11:131-137
    • (2004) Can Respir J , vol.11 , pp. 131-137
    • Marras, T.K.1    Jamieson, L.2    Chan, C.K.3
  • 35
    • 84855410035 scopus 로고    scopus 로고
    • Initial management of pneumonia and sepsis: Factors associated with improved outcome
    • Menéndez R, Torres A, Reyes S, et al: Initial management of pneumonia and sepsis: Factors associated with improved outcome. Eur Respir J 2012; 39:156-162
    • (2012) Eur Respir J , vol.39 , pp. 156-162
    • Menéndez, R.1    Torres, A.2    Reyes, S.3
  • 36
    • 0033994215 scopus 로고    scopus 로고
    • Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation
    • Pascual FE, Matthay MA, Bacchetti P, et al: Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation. Chest 2000; 117:503-512
    • (2000) Chest , vol.117 , pp. 503-512
    • Pascual, F.E.1    Matthay, M.A.2    Bacchetti, P.3
  • 37
    • 0036366750 scopus 로고    scopus 로고
    • Associations between empirical antimicrobial therapy at the hospital and mortality in patients with severe community-acquired pneumonia
    • Rello J, Catalán M, Díaz E, et al: Associations between empirical antimicrobial therapy at the hospital and mortality in patients with severe community-acquired pneumonia. Intensive Care Med 2002; 28:1030-1035
    • (2002) Intensive Care Med , vol.28 , pp. 1030-1035
    • Rello, J.1    Catalán, M.2    Díaz, E.3
  • 38
    • 1542347642 scopus 로고    scopus 로고
    • Causes and factors associated with early failure in hospitalized patients with communityacquired pneumonia
    • Rosón B, Carratalà J, Fernández-Sabé N, et al: Causes and factors associated with early failure in hospitalized patients with communityacquired pneumonia. Arch Intern Med 2004; 164:502-508
    • (2004) Arch Intern Med , vol.164 , pp. 502-508
    • Rosón, B.1    Carratalà, J.2    Fernández-Sabé, N.3
  • 39
    • 37549047144 scopus 로고    scopus 로고
    • Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in asian countries: A prospective study by the asian network for surveillance of resistant pathogens
    • Asian Network for Surveillance of Resistant Pathogens Study Group
    • Song JH, Oh WS, Kang CI, et al; Asian Network for Surveillance of Resistant Pathogens Study Group: Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: A prospective study by the Asian network for surveillance of resistant pathogens. Int J Antimicrob Agents 2008; 31:107-114
    • (2008) Int J Antimicrob Agents , vol.31 , pp. 107-114
    • Song, J.H.1    Oh, W.S.2    Kang, C.I.3
  • 40
    • 29244443967 scopus 로고    scopus 로고
    • Severe community-acquired pneumonia: An Australian perspective
    • Wilson PA, Ferguson J: Severe community-acquired pneumonia: An Australian perspective. Intern Med J 2005; 35:699-705
    • (2005) Intern Med J , vol.35 , pp. 699-705
    • Wilson, P.A.1    Ferguson, J.2
  • 41
    • 35748976854 scopus 로고    scopus 로고
    • Management of communityacquired pneumonia at a tertiary-care teaching hospital
    • Minhas R, Walter SAN, Rachlis A: Management of communityacquired pneumonia at a tertiary-care teaching hospital. Can J Hosp Pharm 2007; 60:245-256
    • (2007) Can J Hosp Pharm , vol.60 , pp. 245-256
    • Minhas, R.1    Walter, S.A.N.2    Rachlis, A.3
  • 42
    • 84895073571 scopus 로고    scopus 로고
    • Comparison of health outcomes among severe community-acquired pneumonia patients treated empirically with a beta-lactam plus a macrolide versus a betalactam plus a fluoroquinolone
    • Frei CR, Restrepo MI, Mortensen EM, et al: Comparison of health outcomes among severe community-acquired pneumonia patients treated empirically with a beta-lactam plus a macrolide versus a betalactam plus a fluoroquinolone. Value Health 2006; 9:A159
    • (2006) Value Health , vol.9 , pp. 159
    • Frei, C.R.1    Restrepo, M.I.2    Mortensen, E.M.3
  • 43
    • 84878769015 scopus 로고    scopus 로고
    • Azithromycin and survival in Streptococcus pneumoniae pneumonia: A retrospective study
    • Shorr AF, Zilberberg MD, Kan J, et al: Azithromycin and survival in Streptococcus pneumoniae pneumonia: A retrospective study. BMJ Open 2013; 3:pii: E002898
    • (2013) BMJ Open , vol.3
    • Shorr, A.F.1    Zilberberg, M.D.2    Kan, J.3
  • 44
    • 84895076814 scopus 로고    scopus 로고
    • Macrolide use in the treatment of critically ill patients with pneumonia: Incidence, correlates, timing, and outcomes
    • in press)
    • Sligl WI, Hoang H, Eurich DT, et al: Macrolide use in the treatment of critically ill patients with pneumonia: Incidence, correlates, timing, and outcomes. Can J Infect Dis Med Microbiol (in press)
    • Can J Infect Dis Med Microbiol
    • Sligl, W.I.1    Hoang, H.2    Eurich, D.T.3
  • 45
    • 84864278373 scopus 로고    scopus 로고
    • Comparison of two guideline-concordant antimicrobial combinations in elderly patients hospitalized with severe community-acquired pneumonia
    • Wilson BZ, Anzueto A, Restrepo MI, et al: Comparison of two guideline-concordant antimicrobial combinations in elderly patients hospitalized with severe community-acquired pneumonia. Crit Care Med 2012; 40:2310-2314
    • (2012) Crit Care Med , vol.40 , pp. 2310-2314
    • Wilson, B.Z.1    Anzueto, A.2    Restrepo, M.I.3
  • 46
    • 84864945655 scopus 로고    scopus 로고
    • Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit: A multicenter study
    • Mongardon N, Max A, Bouglé A, et al: Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit: A multicenter study. Crit Care 2012; 16:R155
    • (2012) Crit Care , vol.16 , pp. 155
    • Mongardon, N.1    Max, A.2    Bouglé, A.3
  • 47
    • 84876289809 scopus 로고    scopus 로고
    • Severe communityacquired pneumonia treated with -lactam-respiratory quinolone vs. -lactam-macrolide combination
    • Karhu J, Ala-Kokko TI, Ohtonen P, et al: Severe communityacquired pneumonia treated with -lactam-respiratory quinolone vs. -lactam-macrolide combination. Acta Anaesthesiol Scand 2013; 57:587-593
    • (2013) Acta Anaesthesiol Scand , vol.57 , pp. 587-593
    • Karhu, J.1    Ala-Kokko, T.I.2    Ohtonen, P.3
  • 48
    • 84878916887 scopus 로고    scopus 로고
    • Mortality differences among hospitalized patients with community-acquired pneumonia in three world regions: Results from the community-acquired pneumonia organization (capo) international cohort study
    • CAPO authors
    • Arnold FW, Wiemken TL, Peyrani P, et al; CAPO authors: Mortality differences among hospitalized patients with community-acquired pneumonia in three world regions: Results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort Study. Respir Med 2013; 107:1101-1111
    • (2013) Respir Med , vol.107 , pp. 1101-1111
    • Arnold, F.W.1    Wiemken, T.L.2    Peyrani, P.3
  • 49
    • 84876204283 scopus 로고    scopus 로고
    • Single versus combination antibiotic therapy in adults hospitalised with community acquired pneumonia
    • British Thoracic Society
    • Rodrigo C, Mckeever TM, Woodhead M, et al; British Thoracic Society: Single versus combination antibiotic therapy in adults hospitalised with community acquired pneumonia. Thorax 2013; 68:493-495
    • (2013) Thorax , vol.68 , pp. 493-495
    • Rodrigo, C.1    McKeever, T.M.2    Woodhead, M.3
  • 50
    • 70349264521 scopus 로고    scopus 로고
    • Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-acquired pneumonia organization international cohort study results
    • Community-Acquired Pneumonia Organization (CAPO) Investigators
    • Arnold FW, LaJoie AS, Brock GN, et al; Community-Acquired Pneumonia Organization (CAPO) Investigators: Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization International cohort study results. Arch Intern Med 2009; 169:1515-1524
    • (2009) Arch Intern Med , vol.169 , pp. 1515-1524
    • Arnold, F.W.1    Lajoie, A.S.2    Brock, G.N.3
  • 51
    • 33846942281 scopus 로고    scopus 로고
    • Macrolide immunomodulation of chronic respiratory diseases
    • Healy DP: Macrolide immunomodulation of chronic respiratory diseases. Curr Infect Dis Rep 2007; 9:7-13
    • (2007) Curr Infect Dis Rep , vol.9 , pp. 7-13
    • Healy, D.P.1
  • 52
    • 33751250175 scopus 로고    scopus 로고
    • The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression
    • ODwyer MJ, Mankan AK, Stordeur P, et al: The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression. Shock 2006; 26:544-550
    • (2006) Shock , vol.26 , pp. 544-550
    • Odwyer, M.J.1    Mankan, A.K.2    Stordeur, P.3
  • 53
    • 84862557241 scopus 로고    scopus 로고
    • Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by Gram-negative bacteria: Results from a randomized clinical study
    • Spyridaki A, Raftogiannis M, Antonopoulou A, et al: Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by Gram-negative bacteria: Results from a randomized clinical study. Antimicrob Agents Chemother 2012; 56:3819-3825
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3819-3825
    • Spyridaki, A.1    Raftogiannis, M.2    Antonopoulou, A.3
  • 54
    • 37149051175 scopus 로고    scopus 로고
    • The need for macrolides in hospitalised community-acquired pneumonia: Propensity analysis
    • Paul M, Nielsen AD, Gafter-Gvili A, et al: The need for macrolides in hospitalised community-acquired pneumonia: Propensity analysis. Eur Respir J 2007; 30:525-531
    • (2007) Eur Respir J , vol.30 , pp. 525-531
    • Paul, M.1    Nielsen, A.D.2    Gafter-Gvili, A.3


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