αDefensins induce a post-translational modification of low density lipoprotein (LDL) that promotes atherosclerosis at normal levels of plasma cholesterol

Journal of Biological Chemistry

Volumn 291, Issue 6, 2016, Pages 2777-2786

  Abu Fanne, Rami ^a   Maraga, Emad ^a   Abd Elrahman, Ihab ^b   Hankin, Aviel ^a   Blum, Galia ^b   Abdeen, Suhair ^a   Hijazi, Nuha ^a   Cines, Douglas B ^c   Higazi, Abd Al Roof ^a,c  

^a School of Pharmacy   (United States)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEPOSITION; DISEASES; LIPOPROTEINS; PATHOLOGY; PLANTS (BOTANY);

ENDOTHELIAL PERMEABILITY; HUMAN NEUTROPHIL; LOW DENSITY LIPOPROTEINS; PLASMA CHOLESTEROL; POLYMORPHONUCLEAR LEUKOCYTES; POST-TRANSLATIONAL MODIFICATIONS; TRANSGENIC MICE; VASCULAR PERMEABILITY;

MAMMALS;

ALPHA DEFENSIN; CATHEPSIN; CHOLESTEROL; COLCHICINE; LOW DENSITY LIPOPROTEIN; MULTIPROTEIN COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD VESSEL PERMEABILITY; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; CHOLESTEROL BLOOD LEVEL; COMPLEX FORMATION; CONTROLLED STUDY; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TRANSPORT; ANIMAL; BLOOD; ENDOTHELIUM CELL; GENETICS; HUMAN; INFLAMMATION; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ALPHA-DEFENSINS; ANIMALS; ATHEROSCLEROSIS; CATHEPSINS; CHOLESTEROL; COLCHICINE; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIPOPROTEINS, LDL; MALE; MICE; MICE, TRANSGENIC; MULTIPROTEIN COMPLEXES; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84958214666     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.669812     Document Type: Article

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