Molecular imaging of Cathepsin B proteolytic enzyme activity reflects the Inflammatory component of atherosclerotic pathology and can quantitatively demonstrate the antiatherosclerotic therapeutic effects of atorvastatin and glucosamine

Molecular Imaging

Volumn 8, Issue 5, 2009, Pages 291-301

  Kim, Dong Eog ^a,b   Kim, Jeong Yeon ^a,b   Schellingerhout, Dawid ^a,b   Shon, Soo Min ^a,b   Jeong, Sang Wuk ^a,b   Kim, Eo Jin ^a,b   Kim, Woo Kyung ^a,b  

^a Dongguk University Ilsan Hospital   (South Korea)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; ATHEROSCLEROTIC PLAQUE; ATORVASTATIN; CATHEPSIN B; CEREBRAL ARTERIES; EX-VIVO; GLUCOSAMINES; HISTOLOGIC EVIDENCE; IMAGING AGENT; INTRAVENOUS INJECTIONS; KNOCKOUT MICE; MOLECULAR IMAGING; NEAR INFRARED; OPTICAL MOLECULAR IMAGING; PROTEASE ACTIVITIES; PROTEOLYTIC ENZYME; SIGNAL INTENSITIES; THERAPEUTIC EFFECTS; VISUAL INSPECTION;

ANIMALS; BIOLOGICAL RADIATION EFFECTS; ECOLOGY; ENZYME ACTIVITY; HISTOLOGY; MACROPHAGES; VISUAL COMMUNICATION;

NUTRITION;

APOLIPOPROTEIN E; ATORVASTATIN; CATHEPSIN B; GLUCOSAMINE; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE;

ANIMAL; ARTICLE; ATHEROSCLEROSIS; CHEMICALLY INDUCED DISORDER; DIAGNOSTIC IMAGING; FLUORESCENCE; GENETICS; METABOLISM; METHODOLOGY; MOUSE; MOUSE MUTANT; PATHOLOGY;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CATHEPSIN B; DIAGNOSTIC IMAGING; FLUORESCENCE; GLUCOSAMINE; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MICE; MICE, KNOCKOUT; PYRROLES;

EID: 70349662290     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2009.00027     Document Type: Article

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