Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation

Free Radical Biology and Medicine

Volumn 93, Issue , 2016, Pages 190-203

  Awasthi, Deepika ^a   Nagarkoti, Sheela ^a   Kumar, Amit ^a   Dubey, Megha ^a   Singh, Abhishek Kumar ^a   Pathak, Priya ^a   Chandra, Tulika ^b   Barthwal, Manoj Kumar ^a   Dikshit, Madhu ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

NADPHoxidase; Neutrophilextracellulartraps; Oxidized lowdensitylipoprotein; Oxidized phospholipids; Systemicinflammatory responsesyndrome

Indexed keywords

1 PALMITOYL 2 ARACHIDONYLGLYCERO 3 PHOSPHORYLCHOLINE; 4 HYDROXYNONENAL; DNA; FREE RADICAL; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; LEUKOCYTE ELASTASE; LYSOPHOSPHATIDYLCHOLINE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDOREDUCTASE INHIBITOR; OXYSTEROL; PHOSPHOLIPID; PROTEIN KINASE C; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE; LOW DENSITY LIPOPROTEIN; TLR2 PROTEIN, HUMAN;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR TRAP; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY BURST; SIGNAL TRANSDUCTION; DRUG EFFECTS; GENETICS; METABOLISM; NEUTROPHIL; OXIDATION REDUCTION REACTION; PATHOLOGY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ALDEHYDES; EXTRACELLULAR TRAPS; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPROTEINS, LDL; MALONDIALDEHYDE; NADPH OXIDASE; NEUTROPHILS; OXIDATION-REDUCTION; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TOLL-LIKE RECEPTOR 2;

EID: 84958178657     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.01.004     Document Type: Article

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