Structure of wild type and mutant F508del CFTR: A small-angle X-ray scattering study of the protein-detergent complexes

Journal of Structural Biology

Volumn 194, Issue 1, 2016, Pages 102-111

  Pollock, Naomi L ^a   Satriano, Letizia ^b   Zegarra Moran, Olga ^c   Ford, Robert C ^a   Moran, Oscar ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CNR   (Italy)

^c G GASLINI INSTITUTE   (Italy)

Author keywords

CFTR; Contrast variation; Cystic fibrosis; Detergent protein complex; F508del; SAXS

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DETERGENT; MUTANT PROTEIN; CFTR PROTEIN, HUMAN;

ARTICLE; COMPLEX FORMATION; DENSITY; ELECTRON; MICELLE; MOLECULAR SIZE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERGENT COMPLEX; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; SURFACE AREA; VOLUME; X RAY CRYSTALLOGRAPHY; ALGORITHM; CHEMISTRY; CYSTIC FIBROSIS; GENETICS; HUMAN; KINETICS; METABOLISM; MUTATION; PROCEDURES; SMALL ANGLE SCATTERING; X RAY DIFFRACTION;

ALGORITHMS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DETERGENTS; HUMANS; KINETICS; MUTATION; PROTEIN CONFORMATION; SCATTERING, SMALL ANGLE; X-RAY DIFFRACTION;

EID: 84958140906     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2016.02.004     Document Type: Article

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