-
1
-
-
38349050413
-
Solubilizing mutations used to crystallize one CFTR domain attenuate the trafficking and channel defects caused by the major cystic fibrosis mutation
-
Pissarra LS, Farinha CM, Xu Z, Schmidt A, Thibodeau PH, et al. (2008) Solubilizing mutations used to crystallize one CFTR domain attenuate the trafficking and channel defects caused by the major cystic fibrosis mutation. Chem Biol 15: 62-69.
-
(2008)
Chem Biol
, vol.15
, pp. 62-69
-
-
Pissarra, L.S.1
Farinha, C.M.2
Xu, Z.3
Schmidt, A.4
Thibodeau, P.H.5
-
3
-
-
0028858161
-
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
-
Jensen TJ, Loo MA, Pind S, Williams DB, Goldberg AL, et al. (1995) Multiple proteolytic systems, including the proteasome, contribute to CFTR processing. Cell 83: 129-135.
-
(1995)
Cell
, vol.83
, pp. 129-135
-
-
Jensen, T.J.1
Loo, M.A.2
Pind, S.3
Williams, D.B.4
Goldberg, A.L.5
-
4
-
-
0035013543
-
The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells
-
Heda GD, Tanwani M, Marino CR, (2001) The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells. Am J Physiol, Cell Physiol 280: C166-174.
-
(2001)
Am J Physiol, Cell Physiol
, vol.280
-
-
Heda, G.D.1
Tanwani, M.2
Marino, C.R.3
-
5
-
-
0030667705
-
Evidence for phosphorylation of serine 753 in CFTR using a novel metal-ion affinity resin and matrix-assisted laser desorption mass spectrometry
-
Neville DC, Rozanas CR, Price EM, Gruis DB, Verkman AS, et al. (1997) Evidence for phosphorylation of serine 753 in CFTR using a novel metal-ion affinity resin and matrix-assisted laser desorption mass spectrometry. Protein Sci 6: 2436-2445.
-
(1997)
Protein Sci
, vol.6
, pp. 2436-2445
-
-
Neville, D.C.1
Rozanas, C.R.2
Price, E.M.3
Gruis, D.B.4
Verkman, A.S.5
-
6
-
-
20844457435
-
Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA
-
Csanády L, Seto-Young D, Chan KW, Cenciarelli C, Angel BB, et al. (2005) Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA. J Gen Physiol 125: 171-186.
-
(2005)
J Gen Physiol
, vol.125
, pp. 171-186
-
-
Csanády, L.1
Seto-Young, D.2
Chan, K.W.3
Cenciarelli, C.4
Angel, B.B.5
-
7
-
-
84555194937
-
Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications
-
McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, et al. (2012) Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel 25: 7-14.
-
(2012)
Protein Eng Des Sel
, vol.25
, pp. 7-14
-
-
McClure, M.1
DeLucas, L.J.2
Wilson, L.3
Ray, M.4
Rowe, S.M.5
-
8
-
-
0037107552
-
Protein kinase CK2: a challenge to canons
-
Pinna LA, (2002) Protein kinase CK2: a challenge to canons. J Cell Sci 115: 3873-3878.
-
(2002)
J Cell Sci
, vol.115
, pp. 3873-3878
-
-
Pinna, L.A.1
-
9
-
-
48249106644
-
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis
-
Pagano MA, Arrigoni G, Marin O, Sarno S, Meggio F, et al. (2008) Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis. Biochemistry 47: 7925-7936.
-
(2008)
Biochemistry
, vol.47
, pp. 7925-7936
-
-
Pagano, M.A.1
Arrigoni, G.2
Marin, O.3
Sarno, S.4
Meggio, F.5
-
10
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
-
Torres J, Pulido R, (2001) The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation. J Biol Chem 276: 993-998.
-
(2001)
J Biol Chem
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
11
-
-
0242298578
-
CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response
-
Kato T Jr, Delhase M, Hoffmann A, Karin M, (2003) CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response. Mol Cell 12: 829-839.
-
(2003)
Mol Cell
, vol.12
, pp. 829-839
-
-
Kato Jr., T.1
Delhase, M.2
Hoffmann, A.3
Karin, M.4
-
12
-
-
33746208870
-
A CK2-dependent mechanism for degradation of the PML tumor suppressor
-
Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ, et al. (2006) A CK2-dependent mechanism for degradation of the PML tumor suppressor. Cell 126: 269-283.
-
(2006)
Cell
, vol.126
, pp. 269-283
-
-
Scaglioni, P.P.1
Yung, T.M.2
Cai, L.F.3
Erdjument-Bromage, H.4
Kaufman, A.J.5
-
13
-
-
83255187903
-
Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity
-
Luz S, Kongsuphol P, Mendes AI, Romeiras F, Sousa M, et al. (2011) Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Mol Cell Biol 31: 4392-4404.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4392-4404
-
-
Luz, S.1
Kongsuphol, P.2
Mendes, A.I.3
Romeiras, F.4
Sousa, M.5
-
14
-
-
84870934566
-
CFTR mutations altering CFTR fragmentation
-
Tosoni K, Stobbart M, Cassidy DM, Venerando A, Pagano MA, et al. (2013) CFTR mutations altering CFTR fragmentation. Biochem J 449: 295-305.
-
(2013)
Biochem J
, vol.449
, pp. 295-305
-
-
Tosoni, K.1
Stobbart, M.2
Cassidy, D.M.3
Venerando, A.4
Pagano, M.A.5
-
15
-
-
0032957204
-
Biosynthesis and Degradation of CFTR
-
Kopito RR, (1999) Biosynthesis and Degradation of CFTR. Physiol Rev 79: S167-S173.
-
(1999)
Physiol Rev
, vol.79
-
-
Kopito, R.R.1
-
16
-
-
0033559258
-
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
-
Meacham GC, Lu Z, King S, Sorscher E, Tousson A, et al. (1999) The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis. EMBO J 18: 1492-1505.
-
(1999)
EMBO J
, vol.18
, pp. 1492-1505
-
-
Meacham, G.C.1
Lu, Z.2
King, S.3
Sorscher, E.4
Tousson, A.5
-
17
-
-
20344378216
-
Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin
-
Farinha CM, Amaral MD, (2005) Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin. Mol Cell Biol 25: 5242-5252.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5242-5252
-
-
Farinha, C.M.1
Amaral, M.D.2
-
18
-
-
2542480784
-
Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator
-
Gentzsch M, Chang X-B, Cui L, Wu Y, Ozols VV, et al. (2004) Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. Mol Biol Cell 15: 2684-2696.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2684-2696
-
-
Gentzsch, M.1
Chang, X.-B.2
Cui, L.3
Wu, Y.4
Ozols, V.V.5
-
19
-
-
0035185231
-
Role of snare proteins in CFTR and ENaC trafficking
-
Peters KW, Qi J, Johnson JP, Watkins SC, Frizzell RA, (2001) Role of snare proteins in CFTR and ENaC trafficking. Pflugers Arch 443Suppl 1: S65-69.
-
(2001)
Pflugers Arch
, vol.443
-
-
Peters, K.W.1
Qi, J.2
Johnson, J.P.3
Watkins, S.C.4
Frizzell, R.A.5
-
20
-
-
84863767664
-
Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae
-
O'Ryan L, Rimington T, Cant N, Ford RC, (2012) Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae. J Vis Exp. 61: e3860.
-
(2012)
J Vis Exp
, vol.61
-
-
O'Ryan, L.1
Rimington, T.2
Cant, N.3
Ford, R.C.4
-
21
-
-
77950601544
-
Isoform specific phosphorylation of p53 by protein kinase CK1
-
Venerando A, Marin O, Cozza G, Bustos VH, Sarno S, et al. (2010) Isoform specific phosphorylation of p53 by protein kinase CK1. Cell Mol Life Sci 67: 1105-1118.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1105-1118
-
-
Venerando, A.1
Marin, O.2
Cozza, G.3
Bustos, V.H.4
Sarno, S.5
-
22
-
-
84856507495
-
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants
-
Salvi M, Trashi E, Marin O, Negro A, Sarno S, et al. (2012) Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. Biochem Biophys Res Commun 418: 156-160.
-
(2012)
Biochem Biophys Res Commun
, vol.418
, pp. 156-160
-
-
Salvi, M.1
Trashi, E.2
Marin, O.3
Negro, A.4
Sarno, S.5
-
23
-
-
0035958465
-
The solid state and solution structure of HAPyU
-
Carpino LA, Henklein P, Foxman BM, Abdelmoty I, Costisella B, et al. (2001) The solid state and solution structure of HAPyU. J Org Chem 66: 5245-5247.
-
(2001)
J Org Chem
, vol.66
, pp. 5245-5247
-
-
Carpino, L.A.1
Henklein, P.2
Foxman, B.M.3
Abdelmoty, I.4
Costisella, B.5
-
24
-
-
34248640261
-
Highly selective enrichment of phosphorylated peptides using titanium dioxide
-
Thingholm TE, Jørgensen TJD, Jensen ON, Larsen MR, (2006) Highly selective enrichment of phosphorylated peptides using titanium dioxide. Nat Protoc 1: 1929-1935.
-
(2006)
Nat Protoc
, vol.1
, pp. 1929-1935
-
-
Thingholm, T.E.1
Jørgensen, T.J.D.2
Jensen, O.N.3
Larsen, M.R.4
-
25
-
-
82755182013
-
Universal and Confident Phosphorylation Site Localization Using phosphoRS
-
Taus T, Köcher T, Pichler P, Paschke C, Schmidt A, et al. (2011) Universal and Confident Phosphorylation Site Localization Using phosphoRS. J Proteome Res 10: 5354-5362.
-
(2011)
J Proteome Res
, vol.10
, pp. 5354-5362
-
-
Taus, T.1
Köcher, T.2
Pichler, P.3
Paschke, C.4
Schmidt, A.5
-
26
-
-
34248679167
-
Tricine-SDS-PAGE
-
Schägger H, (2006) Tricine-SDS-PAGE. Nat Protoc 1: 16-22.
-
(2006)
Nat Protoc
, vol.1
, pp. 16-22
-
-
Schägger, H.1
-
27
-
-
1642464839
-
Protein structure prediction using Rosetta
-
Rohl CA, Strauss CEM, Misura KMS, Baker D, (2004) Protein structure prediction using Rosetta. Meth Enzymol 383: 66-93.
-
(2004)
Meth Enzymol
, vol.383
, pp. 66-93
-
-
Rohl, C.A.1
Strauss, C.E.M.2
Misura, K.M.S.3
Baker, D.4
-
28
-
-
33749020839
-
PIPER: an FFT-based protein docking program with pairwise potentials
-
Kozakov D, Brenke R, Comeau SR, Vajda S, (2006) PIPER: an FFT-based protein docking program with pairwise potentials. Proteins 65: 392-406.
-
(2006)
Proteins
, vol.65
, pp. 392-406
-
-
Kozakov, D.1
Brenke, R.2
Comeau, S.R.3
Vajda, S.4
-
29
-
-
0038526303
-
ZDOCK: An initial-stage protein-docking algorithm
-
Chen R, Li L, Weng Z, (2003) ZDOCK: An initial-stage protein-docking algorithm. Proteins: Structure, Function, and Bioinformatics 52: 80-87.
-
(2003)
Proteins: Structure, Function, and Bioinformatics
, vol.52
, pp. 80-87
-
-
Chen, R.1
Li, L.2
Weng, Z.3
-
30
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
Phillips JC, Braun R, Wang W, Gumbart J, Tajkhorshid E, et al. (2005) Scalable molecular dynamics with NAMD. J Comput Chem 26: 1781-1802.
-
(2005)
J Comput Chem
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
-
31
-
-
0033933777
-
Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase
-
Hallows KR, Raghuram V, Kemp BE, Witters LA, Foskett JK, (2000) Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase. J Clin Invest 105: 1711-1721.
-
(2000)
J Clin Invest
, vol.105
, pp. 1711-1721
-
-
Hallows, K.R.1
Raghuram, V.2
Kemp, B.E.3
Witters, L.A.4
Foskett, J.K.5
-
32
-
-
0032584744
-
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton
-
Short DB, Trotter KW, Reczek D, Kreda SM, Bretscher A, et al. (1998) An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. J Biol Chem 273: 19797-19801.
-
(1998)
J Biol Chem
, vol.273
, pp. 19797-19801
-
-
Short, D.B.1
Trotter, K.W.2
Reczek, D.3
Kreda, S.M.4
Bretscher, A.5
-
33
-
-
0032080043
-
Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)
-
Wang S, Raab RW, Schatz PJ, Guggino WB, Li M, (1998) Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR). FEBS Lett 427: 103-108.
-
(1998)
FEBS Lett
, vol.427
, pp. 103-108
-
-
Wang, S.1
Raab, R.W.2
Schatz, P.J.3
Guggino, W.B.4
Li, M.5
-
34
-
-
0037452680
-
Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia
-
Ostedgaard LS, Randak C, Rokhlina T, Karp P, Vermeer D, et al. (2003) Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia. Proc Natl Acad Sci USA 100: 1937-1942.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1937-1942
-
-
Ostedgaard, L.S.1
Randak, C.2
Rokhlina, T.3
Karp, P.4
Vermeer, D.5
-
35
-
-
84861658918
-
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization
-
Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, et al. (2012) Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science 336: 1150-1153.
-
(2012)
Science
, vol.336
, pp. 1150-1153
-
-
Tagliabracci, V.S.1
Engel, J.L.2
Wen, J.3
Wiley, S.E.4
Worby, C.A.5
-
36
-
-
84864713987
-
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight
-
Lolli G, Cozza G, Mazzorana M, Tibaldi E, Cesaro L, et al. (2012) Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight. Biochemistry 51: 6097-6107.
-
(2012)
Biochemistry
, vol.51
, pp. 6097-6107
-
-
Lolli, G.1
Cozza, G.2
Mazzorana, M.3
Tibaldi, E.4
Cesaro, L.5
-
37
-
-
84867668373
-
Investigation on PLK2 and PLK3 substrate recognition
-
Salvi M, Trashi E, Cozza G, Franchin C, Arrigoni G, et al. (2012) Investigation on PLK2 and PLK3 substrate recognition. Biochim Biophys Acta 1824: 1366-1373.
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 1366-1373
-
-
Salvi, M.1
Trashi, E.2
Cozza, G.3
Franchin, C.4
Arrigoni, G.5
-
38
-
-
34548058372
-
Pharmacological and Functional Comparison of the Polo-like Kinase Family: Insight into Inhibitor and Substrate Specificity
-
Johnson EF, Stewart KD, Woods KW, Giranda VL, Luo Y, (2007) Pharmacological and Functional Comparison of the Polo-like Kinase Family: Insight into Inhibitor and Substrate Specificity. Biochemistry 46: 9551-9563.
-
(2007)
Biochemistry
, vol.46
, pp. 9551-9563
-
-
Johnson, E.F.1
Stewart, K.D.2
Woods, K.W.3
Giranda, V.L.4
Luo, Y.5
-
39
-
-
0036479131
-
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
-
Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, et al. (2002) A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. J Biol Chem 277: 3520-3529.
-
(2002)
J Biol Chem
, vol.277
, pp. 3520-3529
-
-
Cheng, J.1
Moyer, B.D.2
Milewski, M.3
Loffing, J.4
Ikeda, M.5
-
40
-
-
84876938552
-
MAST205 Competes with Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-associated Ligand for Binding to CFTR to Regulate CFTR-mediated Fluid Transport
-
Ren A, Zhang W, Yarlagadda S, Sinha C, Arora K, et al. (2013) MAST205 Competes with Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-associated Ligand for Binding to CFTR to Regulate CFTR-mediated Fluid Transport. J Biol Chem 288: 12325-12334.
-
(2013)
J Biol Chem
, vol.288
, pp. 12325-12334
-
-
Ren, A.1
Zhang, W.2
Yarlagadda, S.3
Sinha, C.4
Arora, K.5
-
41
-
-
0037334895
-
One-thousand-and-one substrates of protein kinase CK2?
-
Meggio F, Pinna LA, (2003) One-thousand-and-one substrates of protein kinase CK2? FASEB J 17: 349-368.
-
(2003)
FASEB J
, vol.17
, pp. 349-368
-
-
Meggio, F.1
Pinna, L.A.2
-
42
-
-
18744377185
-
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator
-
Chen EY, Clarke DM, (2002) The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator. BMC Biochem 3: 29.
-
(2002)
BMC Biochem
, vol.3
, pp. 29
-
-
Chen, E.Y.1
Clarke, D.M.2
-
43
-
-
80053397576
-
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer
-
Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, et al. (2011) Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry 50: 8478-8488.
-
(2011)
Biochemistry
, vol.50
, pp. 8478-8488
-
-
Battistutta, R.1
Cozza, G.2
Pierre, F.3
Papinutto, E.4
Lolli, G.5
-
44
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
Wang X, Venable J, LaPointe P, Hutt DM, Koulov AV, et al. (2006) Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 127: 803-815.
-
(2006)
Cell
, vol.127
, pp. 803-815
-
-
Wang, X.1
Venable, J.2
LaPointe, P.3
Hutt, D.M.4
Koulov, A.V.5
-
45
-
-
84885854021
-
Subverted signalling by protein kinase CK2 in ΔF508 CFTR expressing cells. Poster presentation
-
Venerando A, Pagano MA, Cozza G, Arrigoni G, Mehta A, Pinna LA, (2011) Subverted signalling by protein kinase CK2 in ΔF508 CFTR expressing cells. Poster presentation. FEBS Journal 278: 387.
-
(2011)
FEBS Journal
, vol.278
, pp. 387
-
-
Venerando, A.1
Pagano, M.A.2
Cozza, G.3
Arrigoni, G.4
Mehta, A.5
Pinna, L.A.6
|