Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor

Molecular Cell

Volumn 61, Issue 4, 2016, Pages 602-613

  Fu, Qingshan ^a   Fu, Tian Min ^a,b   Cruz, Anthony C ^c   Sengupta, Prabuddha ^d   Thomas, Stacy K ^c   Wang, Shuqing ^e   Siegel, Richard M ^c   Wu, Hao ^a,b   Chou, James J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR; FAS ANTIGEN; FAS LIGAND; PROLINE; TUMOR NECROSIS FACTOR RECEPTOR; FAS PROTEIN, HUMAN; FAS PROTEIN, MOUSE; LIPID BILAYER;

APOPTOSIS; ARTICLE; CONFORMATION; CONTROLLED STUDY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIPID BILAYER; MOUSE; MUTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ANIMAL; CHEMISTRY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; HEK293 CELLS; HELA CELLS; HUMANS; LIPID BILAYERS; MAGNETIC RESONANCE IMAGING; MICE; MODELS, MOLECULAR; MUTATION; PROLINE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 84958106353     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.01.009     Document Type: Article

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