메뉴 건너뛰기




Volumn 6, Issue 5, 2011, Pages

Modulation of the CD95-induced apoptosis: The role of CD95 N-glycosylation

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; FAS ANTIGEN; GLYCOSYLATED PROTEIN; PROCASPASE 8; SIALIDASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; CASPASE 8; TNFSF10 PROTEIN, HUMAN;

EID: 79956220755     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019927     Document Type: Article
Times cited : (53)

References (57)
  • 3
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takahashi T, Golstein P, Nagata S, (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75: 1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 4
    • 0024347970 scopus 로고
    • Monoclonal antibody-mediated tumor regression by induction of apoptosis
    • Trauth BC, Klas C, Peters AM, Matzku S, Moller P, et al. (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245: 301-305.
    • (1989) Science , vol.245 , pp. 301-305
    • Trauth, B.C.1    Klas, C.2    Peters, A.M.3    Matzku, S.4    Moller, P.5
  • 5
    • 34250346095 scopus 로고    scopus 로고
    • Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling
    • Lavrik IN, Golks A, Riess D, Bentele M, Eils R, et al. (2007) Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling. J Biol Chem 282: 13664-13671.
    • (2007) J Biol Chem , vol.282 , pp. 13664-13671
    • Lavrik, I.N.1    Golks, A.2    Riess, D.3    Bentele, M.4    Eils, R.5
  • 7
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, et al. (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 14: 5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5
  • 9
    • 0037009370 scopus 로고    scopus 로고
    • Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
    • Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, et al. (2002) Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. EMBO J 21: 4520-4530.
    • (2002) EMBO J , vol.21 , pp. 4520-4530
    • Sprick, M.R.1    Rieser, E.2    Stahl, H.3    Grosse-Wilde, A.4    Weigand, M.A.5
  • 10
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, et al. (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85: 817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3    O'Rourke, K.4    Shevchenko, A.5
  • 11
    • 0030826338 scopus 로고    scopus 로고
    • FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b
    • Scaffidi C, Medema JP, Krammer PH, Peter ME, (1997) FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J Biol Chem 272: 26953-26958.
    • (1997) J Biol Chem , vol.272 , pp. 26953-26958
    • Scaffidi, C.1    Medema, J.P.2    Krammer, P.H.3    Peter, M.E.4
  • 13
    • 0034733584 scopus 로고    scopus 로고
    • Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
    • Siegel RM, Frederiksen JK, Zacharias DA, Chan FK, Johnson M, et al. (2000) Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science 288: 2354-2357.
    • (2000) Science , vol.288 , pp. 2354-2357
    • Siegel, R.M.1    Frederiksen, J.K.2    Zacharias, D.A.3    Chan, F.K.4    Johnson, M.5
  • 14
    • 77957794023 scopus 로고    scopus 로고
    • Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus
    • Esposito D, Sankar A, Morgner N, Robinson CV, Rittinger K, et al. (2010) Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus. Structure 18: 1378-1390.
    • (2010) Structure , vol.18 , pp. 1378-1390
    • Esposito, D.1    Sankar, A.2    Morgner, N.3    Robinson, C.V.4    Rittinger, K.5
  • 15
    • 78549236456 scopus 로고    scopus 로고
    • The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations
    • Wang L, Yang JK, Kabaleeswaran V, Rice AJ, Cruz AC, et al. (2010) The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nat Struct Mol Biol 17: 1324-1329.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 1324-1329
    • Wang, L.1    Yang, J.K.2    Kabaleeswaran, V.3    Rice, A.J.4    Cruz, A.C.5
  • 16
    • 60549106191 scopus 로고    scopus 로고
    • The Fas-FADD death domain complex structure unravels signalling by receptor clustering
    • Scott FL, Stec B, Pop C, Dobaczewska MK, Lee JJ, et al. (2009) The Fas-FADD death domain complex structure unravels signalling by receptor clustering. Nature 457: 1019-1022.
    • (2009) Nature , vol.457 , pp. 1019-1022
    • Scott, F.L.1    Stec, B.2    Pop, C.3    Dobaczewska, M.K.4    Lee, J.J.5
  • 18
    • 0028835330 scopus 로고
    • Cell surface sialylation plays a role in modulating sensitivity towards APO-1-mediated apoptotic cell death
    • Peter ME, Hellbardt S, Schwartz-Albiez R, Westendorp MO, Walczak H, et al. (1995) Cell surface sialylation plays a role in modulating sensitivity towards APO-1-mediated apoptotic cell death. Cell Death Differ 2: 163-171.
    • (1995) Cell Death Differ , vol.2 , pp. 163-171
    • Peter, M.E.1    Hellbardt, S.2    Schwartz-Albiez, R.3    Westendorp, M.O.4    Walczak, H.5
  • 19
    • 0033046601 scopus 로고    scopus 로고
    • Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus
    • Keppler OT, Peter ME, Hinderlich S, Moldenhauer G, Stehling P, et al. (1999) Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus. Glycobiology 9: 557-569.
    • (1999) Glycobiology , vol.9 , pp. 557-569
    • Keppler, O.T.1    Peter, M.E.2    Hinderlich, S.3    Moldenhauer, G.4    Stehling, P.5
  • 20
    • 34547098850 scopus 로고    scopus 로고
    • Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells
    • Li Y, Yang X, Nguyen AH, Brockhausen I, (2007) Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells. Int J Biochem Cell Biol 39: 1625-1636.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1625-1636
    • Li, Y.1    Yang, X.2    Nguyen, A.H.3    Brockhausen, I.4
  • 21
    • 34547929295 scopus 로고    scopus 로고
    • Diversity in cell surface sialic acid presentations: implications for biology and disease
    • Varki NM, Varki A, (2007) Diversity in cell surface sialic acid presentations: implications for biology and disease. Lab Invest 87: 851-857.
    • (2007) Lab Invest , vol.87 , pp. 851-857
    • Varki, N.M.1    Varki, A.2
  • 22
    • 48149090000 scopus 로고    scopus 로고
    • Sialic acids in human health and disease
    • Varki A, (2008) Sialic acids in human health and disease. Trends Mol Med 14: 351-360.
    • (2008) Trends Mol Med , vol.14 , pp. 351-360
    • Varki, A.1
  • 24
    • 34948894931 scopus 로고    scopus 로고
    • Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
    • Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, et al. (2007) Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 13: 1070-1077.
    • (2007) Nat Med , vol.13 , pp. 1070-1077
    • Wagner, K.W.1    Punnoose, E.A.2    Januario, T.3    Lawrence, D.A.4    Pitti, R.M.5
  • 26
    • 77949405660 scopus 로고    scopus 로고
    • Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
    • Neumann L, Pforr C, Beaudouin J, Pappa A, Fricker N, et al. (2010) Dynamics within the CD95 death-inducing signaling complex decide life and death of cells. Mol Syst Biol 6: 352.
    • (2010) Mol Syst Biol , vol.6 , pp. 352
    • Neumann, L.1    Pforr, C.2    Beaudouin, J.3    Pappa, A.4    Fricker, N.5
  • 27
    • 0033927710 scopus 로고    scopus 로고
    • Analysis of the CD95 (APO-1/Fas) death-inducing signaling complex by high-resolution two-dimensional gel electrophoresis
    • Scaffidi C, Kischkel FC, Krammer PH, Peter ME, (2000) Analysis of the CD95 (APO-1/Fas) death-inducing signaling complex by high-resolution two-dimensional gel electrophoresis. Methods Enzymol 322: 363-373.
    • (2000) Methods Enzymol , vol.322 , pp. 363-373
    • Scaffidi, C.1    Kischkel, F.C.2    Krammer, P.H.3    Peter, M.E.4
  • 28
    • 33846247103 scopus 로고    scopus 로고
    • Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
    • Feig C, Tchikov V, Schutze S, Peter ME, (2007) Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling. EMBO J 26: 221-231.
    • (2007) EMBO J , vol.26 , pp. 221-231
    • Feig, C.1    Tchikov, V.2    Schutze, S.3    Peter, M.E.4
  • 29
    • 0022883397 scopus 로고
    • Efficient routing of glucocerebrosidase to lysosomes requires complex oligosaccharide chain formation
    • Aerts JM, Brul S, Donker-Koopman WE, van Weely S, Murray GJ, et al. (1986) Efficient routing of glucocerebrosidase to lysosomes requires complex oligosaccharide chain formation. Biochem Biophys Res Commun 141: 452-458.
    • (1986) Biochem Biophys Res Commun , vol.141 , pp. 452-458
    • Aerts, J.M.1    Brul, S.2    Donker-Koopman, W.E.3    van Weely, S.4    Murray, G.J.5
  • 30
    • 4544246088 scopus 로고    scopus 로고
    • Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis
    • Bentele M, Lavrik I, Ulrich M, Stosser S, Heermann DW, et al. (2004) Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis. J Cell Biol 166: 839-851.
    • (2004) J Cell Biol , vol.166 , pp. 839-851
    • Bentele, M.1    Lavrik, I.2    Ulrich, M.3    Stosser, S.4    Heermann, D.W.5
  • 31
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer PH, (2000) CD95's deadly mission in the immune system. Nature 407: 789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 32
    • 2442684321 scopus 로고    scopus 로고
    • Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells
    • Strand S, Vollmer P, van den Abeelen L, Gottfried D, Alla V, et al. (2004) Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells. Oncogene 23: 3732-3736.
    • (2004) Oncogene , vol.23 , pp. 3732-3736
    • Strand, S.1    Vollmer, P.2    van den Abeelen, L.3    Gottfried, D.4    Alla, V.5
  • 33
    • 0020961416 scopus 로고
    • IgM and IgG secretion in human B-cell lines regulated by B-cell-inducing factors (BIF) and phorbol ester
    • Ralph P, Saiki O, Maurer DH, Welte K, (1983) IgM and IgG secretion in human B-cell lines regulated by B-cell-inducing factors (BIF) and phorbol ester. Immunol Lett 7: 17-23.
    • (1983) Immunol Lett , vol.7 , pp. 17-23
    • Ralph, P.1    Saiki, O.2    Maurer, D.H.3    Welte, K.4
  • 34
    • 0039870040 scopus 로고
    • Cytotoxic effector cells specific for B Cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis
    • Svedmyr E, Jondal M, (1975) Cytotoxic effector cells specific for B Cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis. Proc Natl Acad Sci USA 72: 1622-1626.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 1622-1626
    • Svedmyr, E.1    Jondal, M.2
  • 35
    • 0019787147 scopus 로고
    • Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor
    • Gootenberg JE, Ruscetti FW, Mier JW, Gazdar A, Gallo RC, (1981) Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor. J Exp Med 154: 1403-1418.
    • (1981) J Exp Med , vol.154 , pp. 1403-1418
    • Gootenberg, J.E.1    Ruscetti, F.W.2    Mier, J.W.3    Gazdar, A.4    Gallo, R.C.5
  • 36
    • 0001206491 scopus 로고
    • Continuous Culture of Human Lymphoblasts from Peripheral Blood of a Child with Acute Leukemia
    • Foley GE, Lazarus H, Farber S, Uzman BG, Boone BA, et al. (1965) Continuous Culture of Human Lymphoblasts from Peripheral Blood of a Child with Acute Leukemia. Cancer 18: 522-529.
    • (1965) Cancer , vol.18 , pp. 522-529
    • Foley, G.E.1    Lazarus, H.2    Farber, S.3    Uzman, B.G.4    Boone, B.A.5
  • 37
    • 0032505127 scopus 로고    scopus 로고
    • Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
    • Juo P, Kuo CJ, Yuan J, Blenis J, (1998) Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr Biol 8: 1001-1008.
    • (1998) Curr Biol , vol.8 , pp. 1001-1008
    • Juo, P.1    Kuo, C.J.2    Yuan, J.3    Blenis, J.4
  • 38
    • 0017632748 scopus 로고
    • Characterization of "T" and "non-T" cell lines established from children with acute lymphoblastic leukemia and non-Hodgkin lymphoma after leukemic transformation
    • Schneider U, Schwenk HU, (1977) Characterization of "T" and "non-T" cell lines established from children with acute lymphoblastic leukemia and non-Hodgkin lymphoma after leukemic transformation. Haematol Blood Transfus 20: 265-269.
    • (1977) Haematol Blood Transfus , vol.20 , pp. 265-269
    • Schneider, U.1    Schwenk, H.U.2
  • 39
    • 0036732036 scopus 로고    scopus 로고
    • Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death
    • Li-Weber M, Weigand MA, Giaisi M, Suss D, Treiber MK, et al. (2002) Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death. J Clin Invest 110: 681-690.
    • (2002) J Clin Invest , vol.110 , pp. 681-690
    • Li-Weber, M.1    Weigand, M.A.2    Giaisi, M.3    Suss, D.4    Treiber, M.K.5
  • 40
    • 85025402749 scopus 로고
    • Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix
    • Scherer WF, Syverton JT, Gey GO, (1953) Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix. J Exp Med 97: 695-710.
    • (1953) J Exp Med , vol.97 , pp. 695-710
    • Scherer, W.F.1    Syverton, J.T.2    Gey, G.O.3
  • 41
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • Graham FL, Smiley J, Russell WC, Nairn R, (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36: 59-74.
    • (1977) J Gen Virol , vol.36 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 42
    • 0034142374 scopus 로고    scopus 로고
    • Phosphorylation of FADD/MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase
    • Scaffidi C, Volkland J, Blomberg I, Hoffmann I, Krammer PH, et al. (2000) Phosphorylation of FADD/MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase. J Immunol 164: 1236-1242.
    • (2000) J Immunol , vol.164 , pp. 1236-1242
    • Scaffidi, C.1    Volkland, J.2    Blomberg, I.3    Hoffmann, I.4    Krammer, P.H.5
  • 43
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C, Schmitz I, Krammer PH, Peter ME, (1999) The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 274: 1541-1548.
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 44
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5: 157-163.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3    Gliniak, B.4    Griffith, T.S.5
  • 45
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
    • Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, et al. (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J Biol Chem 267: 10709-10715.
    • (1992) J Biol Chem , vol.267 , pp. 10709-10715
    • Oehm, A.1    Behrmann, I.2    Falk, W.3    Pawlita, M.4    Maier, G.5
  • 46
    • 37749004229 scopus 로고    scopus 로고
    • Structure-function relationships of Toll-like receptor domains through homology modelling and molecular dynamics
    • Kubarenko A, Frank M, Weber AN, (2007) Structure-function relationships of Toll-like receptor domains through homology modelling and molecular dynamics. Biochem Soc Trans 35: 1515-1518.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1515-1518
    • Kubarenko, A.1    Frank, M.2    Weber, A.N.3
  • 47
    • 77249096457 scopus 로고    scopus 로고
    • Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains
    • Kubarenko A, Ranjan S, Colak E, George J, Frank M, et al. (2009) Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains. Protein Sci 19: 558-569.
    • (2009) Protein Sci , vol.19 , pp. 558-569
    • Kubarenko, A.1    Ranjan, S.2    Colak, E.3    George, J.4    Frank, M.5
  • 48
    • 0028051828 scopus 로고
    • Derivation of rules for comparative protein modeling from a database of protein structure alignments
    • Sali A, Overington JP, (1994) Derivation of rules for comparative protein modeling from a database of protein structure alignments. Protein Sci 3: 1582-1596.
    • (1994) Protein Sci , vol.3 , pp. 1582-1596
    • Sali, A.1    Overington, J.P.2
  • 49
    • 0029069758 scopus 로고
    • Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor
    • Naismith JH, Devine TQ, Brandhuber BJ, Sprang SR, (1995) Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J Biol Chem 270: 13303-13307.
    • (1995) J Biol Chem , vol.270 , pp. 13303-13307
    • Naismith, J.H.1    Devine, T.Q.2    Brandhuber, B.J.3    Sprang, S.R.4
  • 50
    • 0027211704 scopus 로고
    • Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation
    • Banner DW, D'Arcy A, Janes W, Gentz R, Schoenfeld HJ, et al. (1993) Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 73: 431-445.
    • (1993) Cell , vol.73 , pp. 431-445
    • Banner, D.W.1    D'Arcy, A.2    Janes, W.3    Gentz, R.4    Schoenfeld, H.J.5
  • 52
    • 0033212968 scopus 로고    scopus 로고
    • Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5
    • Hymowitz SG, Christinger HW, Fuh G, Ultsch M, O'Connell M, et al. (1999) Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol Cell 4: 563-571.
    • (1999) Mol Cell , vol.4 , pp. 563-571
    • Hymowitz, S.G.1    Christinger, H.W.2    Fuh, G.3    Ultsch, M.4    O'Connell, M.5
  • 56
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling
    • Guex N, Peitsch MC, (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18: 2714-2723.
    • (1997) Electrophoresis , vol.18 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 57
    • 77249096457 scopus 로고    scopus 로고
    • Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains
    • Kubarenko AV, Ranjan S, Colak E, George J, Frank M, et al. (2010) Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains. Protein Sci.
    • (2010) Protein Sci
    • Kubarenko, A.V.1    Ranjan, S.2    Colak, E.3    George, J.4    Frank, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.