-
1
-
-
84969325747
-
-
Available from:, Oct
-
WHO. World Malaria Report 2014; [cited 23Oct 2015]. Available from: http://www.who.int/malaria/publications/world_malaria_report_2014/en/
-
World Malaria Report 2014
-
-
-
2
-
-
84944195470
-
The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015
-
S.Bhatt, D.J.Weiss, E.Cameron, et al. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015;526:207–211.
-
(2015)
Nature
, vol.526
, pp. 207-211
-
-
Bhatt, S.1
Weiss, D.J.2
Cameron, E.3
-
4
-
-
84951079707
-
RTS, S: toward a first landmark on the Malaria Vaccine Technology Roadmap
-
pii: S0264-410X(15)01337-7
-
D.C.Kaslow, S.Biernaux RTS, S: toward a first landmark on the Malaria Vaccine Technology Roadmap. Vaccine. 2015 pii: S0264-410X(15)01337-7. doi:10.1016/j.vaccine.2015.09.061.
-
(2015)
Vaccine
-
-
Kaslow, D.C.1
Biernaux, S.2
-
5
-
-
84937422078
-
Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial
-
RTS,S Clinical Trials Partnership. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet. 2015;386:31–45.
-
(2015)
Lancet
, vol.386
, pp. 31-45
-
-
-
6
-
-
84951567221
-
Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial
-
pii: S1473-3099(15)00239-X
-
M.T.White, R.Verity, J.T.Griffin, et al. Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. Lancet Infect Dis. 2015 pii: S1473-3099(15)00239-X. doi:10.1016/S1473-3099(15)00239-X.
-
(2015)
Lancet Infect Dis
-
-
White, M.T.1
Verity, R.2
Griffin, J.T.3
-
7
-
-
33644871833
-
Immune effector mechanisms in malaria
-
K.Marsh, S.Kinyanjui. Immune effector mechanisms in malaria. Parasite Immunol. 2006;28:51–60.
-
(2006)
Parasite Immunol
, vol.28
, pp. 51-60
-
-
Marsh, K.1
Kinyanjui, S.2
-
8
-
-
8144224632
-
Gamma-globulin and acquired immunity to human malaria
-
S.Cohen, G.I.Mc, S.Carrington. Gamma-globulin and acquired immunity to human malaria. Nature. 1961;192:733–737.•• The first passive transfer study in human. The study has shown that antibody is the main player of protective immunity against blood-stage malaria.
-
(1961)
Nature
, vol.192
, pp. 733-737
-
-
Cohen, S.1
Mc, G.I.2
Carrington, S.3
-
9
-
-
0025953526
-
Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria
-
A.Sabchareon, T.Burnouf, D.Ouattara, et al. Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria. Am J Trop Med Hyg. 1991;45:297–308.• The second passive transfer study in human. The study has shown that antibodies from Africa can kill parasites in Thai.
-
(1991)
Am J Trop Med Hyg
, vol.45
, pp. 297-308
-
-
Sabchareon, A.1
Burnouf, T.2
Ouattara, D.3
-
11
-
-
84936948009
-
Developing vaccines to prevent malaria in pregnant women
-
N.Tuikue-Ndam, P.Deloron. Developing vaccines to prevent malaria in pregnant women. Expert Opin Biol Ther. 2015;15:1173–1182.
-
(2015)
Expert Opin Biol Ther
, vol.15
, pp. 1173-1182
-
-
Tuikue-Ndam, N.1
Deloron, P.2
-
12
-
-
84951155879
-
Development of vaccines for Plasmodium vivax malaria
-
pii: S0264-410X(15)01336-5
-
I.Mueller, A.R.Shakri, C.E.Chitnis. Development of vaccines for Plasmodium vivax malaria. Vaccine. 2015 pii: S0264-410X(15)01336-5. doi:10.1016/j.vaccine.2015.09.060.
-
(2015)
Vaccine
-
-
Mueller, I.1
Shakri, A.R.2
Chitnis, C.E.3
-
13
-
-
84965090753
-
Landmark green light for Mosquirix malaria vaccine
-
C.Morrison. Landmark green light for Mosquirix malaria vaccine. Nat Biotechnol. 2015;33:1015–1016.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 1015-1016
-
-
Morrison, C.1
-
14
-
-
77951078453
-
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
-
P.D.Crompton, M.A.Kayala, B.Traore, et al. A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray. Proc Natl Acad Sci U S A. 2010;107:6958–6963.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 6958-6963
-
-
Crompton, P.D.1
Kayala, M.A.2
Traore, B.3
-
15
-
-
56949090515
-
A phase 1 trial of PfCP2.9: an AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malaria
-
E.Malkin, J.Hu, Z.Li, et al. A phase 1 trial of PfCP2.9: an AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malaria. Vaccine. 2008;26:6864–6873.
-
(2008)
Vaccine
, vol.26
, pp. 6864-6873
-
-
Malkin, E.1
Hu, J.2
Li, Z.3
-
16
-
-
44849120805
-
Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults
-
J.Hu, Z.Chen, J.Gu, et al. Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults. PLoS One. 2008;3:e1952.
-
(2008)
PLoS One
, vol.3
, pp. e1952
-
-
Hu, J.1
Chen, Z.2
Gu, J.3
-
17
-
-
75749098881
-
The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: a systematic review and meta-analysis
-
F.J.Fowkes, J.S.Richards, J.A.Simpson, et al. The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: a systematic review and meta-analysis. PLoS Med. 2010;7:e1000218.• This meta-analysis study has clearly shown the interpretation of immune correlates of protection in epidemiological studies is complicated.
-
(2010)
PLoS Med
, vol.7
, pp. e1000218
-
-
Fowkes, F.J.1
Richards, J.S.2
Simpson, J.A.3
-
18
-
-
84863683912
-
Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?
-
C.J.Duncan, A.V.Hill. Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy? Hum Vaccin Immunother. 2012;8:706–714.
-
(2012)
Hum Vaccin Immunother
, vol.8
, pp. 706-714
-
-
Duncan, C.J.1
Hill, A.V.2
-
19
-
-
77957841696
-
Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia
-
J.S.Richards, D.I.Stanisic, F.J.Fowkes, et al. Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia. Clin Infect Dis. 2010;51:e50–60.
-
(2010)
Clin Infect Dis
, vol.51
, pp. e50-e60
-
-
Richards, J.S.1
Stanisic, D.I.2
Fowkes, F.J.3
-
20
-
-
84887908446
-
Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria
-
J.Rono, F.H.Osier, D.Olsson, et al. Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria. Clin Infect Dis. 2013;57:1409–1416.
-
(2013)
Clin Infect Dis
, vol.57
, pp. 1409-1416
-
-
Rono, J.1
Osier, F.H.2
Olsson, D.3
-
21
-
-
84857682112
-
Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development
-
D.K.Moss, E.J.Remarque, B.W.Faber, et al. Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development. Infect Immun. 2012;80:1280–1287.
-
(2012)
Infect Immun
, vol.80
, pp. 1280-1287
-
-
Moss, D.K.1
Remarque, E.J.2
Faber, B.W.3
-
22
-
-
33750576557
-
Critical evaluation of different methods for measuring the functional activity of antibodies against malaria blood stage antigens
-
E.S.Bergmann-Leitner, E.H.Duncan, G.E.Mullen, et al. Critical evaluation of different methods for measuring the functional activity of antibodies against malaria blood stage antigens. Am J Trop Med Hyg. 2006;75:437–442.
-
(2006)
Am J Trop Med Hyg
, vol.75
, pp. 437-442
-
-
Bergmann-Leitner, E.S.1
Duncan, E.H.2
Mullen, G.E.3
-
23
-
-
21144469605
-
Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria
-
E.M.Malkin, D.J.Diemert, J.H.McArthur, et al. Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria. Infect Immun. 2005;73:3677–3685.
-
(2005)
Infect Immun
, vol.73
, pp. 3677-3685
-
-
Malkin, E.M.1
Diemert, D.J.2
McArthur, J.H.3
-
24
-
-
34247355050
-
Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research
-
M.E.Polhemus, A.J.Magill, J.F.Cummings, et al. Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research. Vaccine. 2007;25:4203–4212.
-
(2007)
Vaccine
, vol.25
, pp. 4203-4212
-
-
Polhemus, M.E.1
Magill, A.J.2
Cummings, J.F.3
-
25
-
-
58049090288
-
Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02
-
M.Roestenberg, E.Remarque, E.De Jonge, et al. Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02. PLoS One. 2008;3:e3960.
-
(2008)
PLoS One
, vol.3
, pp. e3960
-
-
Roestenberg, M.1
Remarque, E.2
De Jonge, E.3
-
26
-
-
77749319159
-
Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naive adults
-
R.D.Ellis, L.B.Martin, D.Shaffer, et al. Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naive adults. PLoS One. 2010;5:e8787.
-
(2010)
PLoS One
, vol.5
, pp. e8787
-
-
Ellis, R.D.1
Martin, L.B.2
Shaffer, D.3
-
27
-
-
77957872219
-
Safety and immunogenicity of a recombinant nonglycosylated erythrocyte binding antigen 175 Region II malaria vaccine in healthy adults living in an area where malaria is not endemic
-
H.M.El Sahly, S.M.Patel, R.L.Atmar, et al. Safety and immunogenicity of a recombinant nonglycosylated erythrocyte binding antigen 175 Region II malaria vaccine in healthy adults living in an area where malaria is not endemic. Clin Vaccine Immunol. 2010;17:1552–1559.
-
(2010)
Clin Vaccine Immunol
, vol.17
, pp. 1552-1559
-
-
El Sahly, H.M.1
Patel, S.M.2
Atmar, R.L.3
-
28
-
-
40449105608
-
Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians
-
A.Dicko, D.J.Diemert, I.Sagara, et al. Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians. PLoS One. 2007;2:e1045.
-
(2007)
PLoS One
, vol.2
, pp. e1045
-
-
Dicko, A.1
Diemert, D.J.2
Sagara, I.3
-
29
-
-
44849126049
-
Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial
-
M.A.Thera, O.K.Doumbo, D.Coulibaly, et al. Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial. PLoS One. 2008;3:e1465.
-
(2008)
PLoS One
, vol.3
, pp. e1465
-
-
Thera, M.A.1
Doumbo, O.K.2
Coulibaly, D.3
-
30
-
-
79951810036
-
Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized
-
K.Miura, H.Zhou, A.Diouf, et al. Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized. Vaccine. 2011;29:2255–2261.
-
(2011)
Vaccine
, vol.29
, pp. 2255-2261
-
-
Miura, K.1
Zhou, H.2
Diouf, A.3
-
31
-
-
79958714529
-
Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay
-
K.Miura, S.Perera, S.Brockley, et al. Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay. PLoS One. 2011;6:e20947.
-
(2011)
PLoS One
, vol.6
, pp. e20947
-
-
Miura, K.1
Perera, S.2
Brockley, S.3
-
32
-
-
58849117152
-
Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination
-
K.Miura, H.Zhou, S.E.Moretz, et al. Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination. J Immunol. 2008;181:8776–8783.
-
(2008)
J Immunol
, vol.181
, pp. 8776-8783
-
-
Miura, K.1
Zhou, H.2
Moretz, S.E.3
-
33
-
-
79960671082
-
Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909
-
C.J.Duncan, S.H.Sheehy, K.J.Ewer, et al. Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909. PLoS One. 2011;6:e22271.
-
(2011)
PLoS One
, vol.6
, pp. e22271
-
-
Duncan, C.J.1
Sheehy, S.H.2
Ewer, K.J.3
-
34
-
-
74949118446
-
High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model
-
S.Dutta, J.S.Sullivan, K.K.Grady, et al. High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model. PLoS One. 2009;4:e8138.
-
(2009)
PLoS One
, vol.4
, pp. e8138
-
-
Dutta, S.1
Sullivan, J.S.2
Grady, K.K.3
-
35
-
-
33746645179
-
Immunity to recombinant Plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity
-
S.Singh, K.Miura, H.Zhou, et al. Immunity to recombinant Plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity. Infect Immun. 2006;74:4573–4580.
-
(2006)
Infect Immun
, vol.74
, pp. 4573-4580
-
-
Singh, S.1
Miura, K.2
Zhou, H.3
-
36
-
-
84925004026
-
Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria
-
M.J.Boyle, L.Reiling, G.Feng, et al. Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria. Immunity. 2015;42:580–590.
-
(2015)
Immunity
, vol.42
, pp. 580-590
-
-
Boyle, M.J.1
Reiling, L.2
Feng, G.3
-
37
-
-
77956274903
-
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
-
M.J.Boyle, D.W.Wilson, J.S.Richards, et al. Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development. Proc Natl Acad Sci U S A. 2010;107:14378–14383.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14378-14383
-
-
Boyle, M.J.1
Wilson, D.W.2
Richards, J.S.3
-
38
-
-
0029098383
-
Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages
-
H.Bouharoun-Tayoun, C.Oeuvray, F.Lunel, et al. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J Exp Biol. 1995;182:409–418.
-
(1995)
J Exp Biol
, vol.182
, pp. 409-418
-
-
Bouharoun-Tayoun, H.1
Oeuvray, C.2
Lunel, F.3
-
39
-
-
0025606095
-
Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes
-
H.Bouharoun-Tayoun, P.Attanath, A.Sabchareon, et al. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J Exp Med. 1990;172:1633–1641.
-
(1990)
J Exp Med
, vol.172
, pp. 1633-1641
-
-
Bouharoun-Tayoun, H.1
Attanath, P.2
Sabchareon, A.3
-
40
-
-
80052882697
-
A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide ISA 720
-
J.S.McCarthy, J.Marjason, S.Elliott, et al. A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide ISA 720. PLoS One. 2011;6:e24413.
-
(2011)
PLoS One
, vol.6
, pp. e24413
-
-
McCarthy, J.S.1
Marjason, J.2
Elliott, S.3
-
41
-
-
28444486411
-
A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum
-
P.Druilhe, F.Spertini, D.Soesoe, et al. A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum. PLoS Med. 2005;2:e344.
-
(2005)
PLoS Med
, vol.2
, pp. e344
-
-
Druilhe, P.1
Spertini, F.2
Soesoe, D.3
-
42
-
-
33947107414
-
Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial
-
C.C.Hermsen, D.F.Verhage, D.S.Telgt, et al. Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial. Vaccine. 2007;25:2930–2940.
-
(2007)
Vaccine
, vol.25
, pp. 2930-2940
-
-
Hermsen, C.C.1
Verhage, D.F.2
Telgt, D.S.3
-
43
-
-
84902323912
-
Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences
-
M.Yagi, G.Bang, T.Tougan, et al. Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences. PLoS One. 2014;9:e98460.
-
(2014)
PLoS One
, vol.9
, pp. e98460
-
-
Yagi, M.1
Bang, G.2
Tougan, T.3
-
44
-
-
73449144152
-
A distinct peripheral blood monocyte phenotype is associated with parasite inhibitory activity in acute uncomplicated Plasmodium falciparum malaria
-
P.Chimma, C.Roussilhon, P.Sratongno, et al. A distinct peripheral blood monocyte phenotype is associated with parasite inhibitory activity in acute uncomplicated Plasmodium falciparum malaria. PLoS Pathog. 2009;5:e1000631.
-
(2009)
PLoS Pathog
, vol.5
, pp. e1000631
-
-
Chimma, P.1
Roussilhon, C.2
Sratongno, P.3
-
45
-
-
0345040646
-
Differential effect and interaction of monocytes, hyperimmune sera, and immunoglobulin G on the growth of asexual stage Plasmodium falciparum parasites
-
Y.P.Shi, V.Udhayakumar, A.J.Oloo, et al. Differential effect and interaction of monocytes, hyperimmune sera, and immunoglobulin G on the growth of asexual stage Plasmodium falciparum parasites. Am J Trop Med Hyg. 1999;60:135–141.
-
(1999)
Am J Trop Med Hyg
, vol.60
, pp. 135-141
-
-
Shi, Y.P.1
Udhayakumar, V.2
Oloo, A.J.3
-
46
-
-
84927677624
-
High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays
-
R.W.Tiendrebeogo, B.Adu, S.K.Singh, et al. High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays. Malar J. 2014;13:412.
-
(2014)
Malar J
, vol.13
, pp. 412
-
-
Tiendrebeogo, R.W.1
Adu, B.2
Singh, S.K.3
-
47
-
-
84883606588
-
Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria
-
D.L.Hill, E.M.Eriksson, C.S.Li Wai Suen, et al. Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria. PLoS One. 2013;8:e74627.
-
(2013)
PLoS One
, vol.8
, pp. e74627
-
-
Hill, D.L.1
Eriksson, E.M.2
Li Wai Suen, C.S.3
-
48
-
-
84904305506
-
Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria
-
F.H.Osier, G.Feng, M.J.Boyle, et al. Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria. BMC Med. 2014;12:108.
-
(2014)
BMC Med
, vol.12
, pp. 108
-
-
Osier, F.H.1
Feng, G.2
Boyle, M.J.3
-
49
-
-
79551633850
-
Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum
-
A.Ghumra, P.Khunrae, R.Ataide, et al. Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum. PLoS One. 2011;6:e16414.
-
(2011)
PLoS One
, vol.6
, pp. e16414
-
-
Ghumra, A.1
Khunrae, P.2
Ataide, R.3
-
50
-
-
84865963674
-
Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity
-
J.A.Chan, K.B.Howell, L.Reiling, et al. Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity. J Clin Invest. 2012;122:3227–3238.
-
(2012)
J Clin Invest
, vol.122
, pp. 3227-3238
-
-
Chan, J.A.1
Howell, K.B.2
Reiling, L.3
-
51
-
-
84935524608
-
CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so
-
J.Zhou, G.Feng, J.Beeson, et al. CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so. BMC Med. 2015;13:154.
-
(2015)
BMC Med
, vol.13
, pp. 154
-
-
Zhou, J.1
Feng, G.2
Beeson, J.3
-
52
-
-
0025909820
-
The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII
-
H.B.Fleit, C.D.Kobasiuk. The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII. J Leukoc Biol. 1991;49:556–565.
-
(1991)
J Leukoc Biol
, vol.49
, pp. 556-565
-
-
Fleit, H.B.1
Kobasiuk, C.D.2
-
53
-
-
57549095016
-
Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites
-
P.R.Gilson, B.S.Crabb. Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites. Int J Parasitol. 2009;39:91–96.
-
(2009)
Int J Parasitol
, vol.39
, pp. 91-96
-
-
Gilson, P.R.1
Crabb, B.S.2
-
54
-
-
77956274903
-
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
-
M.J.Boyle, D.W.Wilson, J.S.Richards, et al. Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development. Proc Natl Acad Sci USA. 2010;107:14378–14383.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14378-14383
-
-
Boyle, M.J.1
Wilson, D.W.2
Richards, J.S.3
-
55
-
-
84908656907
-
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
-
J.A.Chan, F.J.Fowkes, J.G.Beeson. Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates. Cell Mol Life Sci. 2014;71:3633–3657.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 3633-3657
-
-
Chan, J.A.1
Fowkes, F.J.2
Beeson, J.G.3
-
56
-
-
84871842977
-
A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies
-
A.Bengtsson, L.Joergensen, T.S.Rask, et al. A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies. J Immunol. 2013;190:240–249.
-
(2013)
J Immunol
, vol.190
, pp. 240-249
-
-
Bengtsson, A.1
Joergensen, L.2
Rask, T.S.3
-
57
-
-
84872676939
-
Analysis of antibody induction upon immunization with distinct NTS-DBL1alpha-domains of PfEMP1 from rosetting Plasmodium falciparum parasites
-
D.Angeletti, L.Albrecht, M.Wahlgren, et al. Analysis of antibody induction upon immunization with distinct NTS-DBL1alpha-domains of PfEMP1 from rosetting Plasmodium falciparum parasites. Malar J. 2013;12:32.
-
(2013)
Malar J
, vol.12
, pp. 32
-
-
Angeletti, D.1
Albrecht, L.2
Wahlgren, M.3
-
58
-
-
84941730216
-
Immunogenicity of the Plasmodium falciparum PfEMP1-VarO adhesin: induction of surface-reactive and rosette-disrupting antibodies to VarO infected erythrocytes
-
M.Guillotte, A.Juillerat, S.Igonet, et al. Immunogenicity of the Plasmodium falciparum PfEMP1-VarO adhesin: induction of surface-reactive and rosette-disrupting antibodies to VarO infected erythrocytes. PLoS One. 2015;10:e0134292.
-
(2015)
PLoS One
, vol.10
, pp. e0134292
-
-
Guillotte, M.1
Juillerat, A.2
Igonet, S.3
-
59
-
-
84928206210
-
PfEMP1 - a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
-
L.Hviid, A.T.Jensen. PfEMP1 - a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis. Adv Parasitol. 2015;88:51–84.
-
(2015)
Adv Parasitol
, vol.88
, pp. 51-84
-
-
Hviid, L.1
Jensen, A.T.2
-
60
-
-
77957784634
-
Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies
-
C.Joos, L.Marrama, H.E.Polson, et al. Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies. PLoS One. 2010;5:e9871.
-
(2010)
PLoS One
, vol.5
, pp. e9871
-
-
Joos, C.1
Marrama, L.2
Polson, H.E.3
-
61
-
-
84941770213
-
Standardization of the antibody-dependent respiratory burst assay with human neutrophils and Plasmodium falciparum malaria
-
D.Llewellyn, K.Miura, M.P.Fay, et al. Standardization of the antibody-dependent respiratory burst assay with human neutrophils and Plasmodium falciparum malaria. Sci Rep. 2015;5:14081.
-
(2015)
Sci Rep
, vol.5
, pp. 14081
-
-
Llewellyn, D.1
Miura, K.2
Fay, M.P.3
-
62
-
-
0042265108
-
DNA immunization with the cysteine-rich interdomain region 1 of the Plasmodium falciparum variant antigen elicits limited cross-reactive antibody responses
-
D.I.Baruch, B.Gamain, L.H.Miller. DNA immunization with the cysteine-rich interdomain region 1 of the Plasmodium falciparum variant antigen elicits limited cross-reactive antibody responses. Infect Immun. 2003;71:4536–4543.
-
(2003)
Infect Immun
, vol.71
, pp. 4536-4543
-
-
Baruch, D.I.1
Gamain, B.2
Miller, L.H.3
-
63
-
-
84876084796
-
Structure-function-immunogenicity studies of PfEMP1 domain DBL2betaPF11_0521, a malaria parasite ligand for ICAM-1
-
J.Gullingsrud, T.Saveria, E.Amos, et al. Structure-function-immunogenicity studies of PfEMP1 domain DBL2betaPF11_0521, a malaria parasite ligand for ICAM-1. PLoS One. 2013;8:e61323.
-
(2013)
PLoS One
, vol.8
, pp. e61323
-
-
Gullingsrud, J.1
Saveria, T.2
Amos, E.3
-
64
-
-
84944463301
-
Multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variants per genome can bind IgM via Fcμ
-
A.Jeppesen, S.B.Ditlev, V.Soroka, et al. Multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variants per genome can bind IgM via Fcμ. Infect Immun. 2015;83:3972–3981.
-
(2015)
Infect Immun
, vol.83
, pp. 3972-3981
-
-
Jeppesen, A.1
Ditlev, S.B.2
Soroka, V.3
-
65
-
-
84942465626
-
Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
-
F.Lennartz, A.Bengtsson, R.W.Olsen, et al. Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding. J Immunol. 2015;195:3273–3283.
-
(2015)
J Immunol
, vol.195
, pp. 3273-3283
-
-
Lennartz, F.1
Bengtsson, A.2
Olsen, R.W.3
-
66
-
-
33644904970
-
Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine
-
C.F.Ockenhouse, E.Angov, K.E.Kester, et al. Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine. Vaccine. 2006;24:3009–3017.
-
(2006)
Vaccine
, vol.24
, pp. 3009-3017
-
-
Ockenhouse, C.F.1
Angov, E.2
Kester, K.E.3
-
67
-
-
68249135238
-
Humoral and cell-mediated immunity to MSP3 peptides in adults immunized with MSP3 in malaria endemic area, Burkina Faso
-
I.Nebie, A.Diarra, A.Ouedraogo, et al. Humoral and cell-mediated immunity to MSP3 peptides in adults immunized with MSP3 in malaria endemic area, Burkina Faso. Parasite Immunol. 2009;31:474–480.
-
(2009)
Parasite Immunol
, vol.31
, pp. 474-480
-
-
Nebie, I.1
Diarra, A.2
Ouedraogo, A.3
-
68
-
-
65449181983
-
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A
-
M.D.Spring, J.F.Cummings, C.F.Ockenhouse, et al. Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A. PLoS One. 2009;4:e5254.
-
(2009)
PLoS One
, vol.4
, pp. e5254
-
-
Spring, M.D.1
Cummings, J.F.2
Ockenhouse, C.F.3
-
69
-
-
84857399087
-
Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors
-
S.H.Sheehy, C.J.Duncan, S.C.Elias, et al. Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors. PLoS One. 2012;7:e31208.
-
(2012)
PLoS One
, vol.7
, pp. e31208
-
-
Sheehy, S.H.1
Duncan, C.J.2
Elias, S.C.3
-
70
-
-
84927173990
-
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1 - report on a phase Ia clinical trial
-
S.H.Hodgson, P.Choudhary, S.C.Elias, et al. Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1 - report on a phase Ia clinical trial. Mol Ther. 2014;22:2142–2154.
-
(2014)
Mol Ther
, vol.22
, pp. 2142-2154
-
-
Hodgson, S.H.1
Choudhary, P.2
Elias, S.C.3
-
71
-
-
0037167246
-
Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum
-
D.J.Pombo, G.Lawrence, C.Hirunpetcharat, et al. Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet. 2002;360:610–617.
-
(2002)
Lancet
, vol.360
, pp. 610-617
-
-
Pombo, D.J.1
Lawrence, G.2
Hirunpetcharat, C.3
-
72
-
-
25844497079
-
Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration
-
M.D.Edstein, B.M.Kotecka, K.L.Anderson, et al. Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration. Antimicrob Agents Chemother. 2005;49:4421–4422.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4421-4422
-
-
Edstein, M.D.1
Kotecka, B.M.2
Anderson, K.L.3
-
73
-
-
0034469316
-
Efficacy of vaccines containing rhoptry-associated proteins RAP1 and RAP2 of Plasmodium falciparum in Saimiri boliviensis monkeys
-
W.E.Collins, A.Walduck, J.S.Sullivan, et al. Efficacy of vaccines containing rhoptry-associated proteins RAP1 and RAP2 of Plasmodium falciparum in Saimiri boliviensis monkeys. Am J Trop Med Hyg. 2000;62:466–479.
-
(2000)
Am J Trop Med Hyg
, vol.62
, pp. 466-479
-
-
Collins, W.E.1
Walduck, A.2
Sullivan, J.S.3
-
74
-
-
0036893441
-
Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria
-
A.W.Stowers, M.C.Kennedy, B.P.Keegan, et al. Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria. Infect Immun. 2002;70:6961–6967.
-
(2002)
Infect Immun
, vol.70
, pp. 6961-6967
-
-
Stowers, A.W.1
Kennedy, M.C.2
Keegan, B.P.3
-
75
-
-
11144355858
-
Immunization of Saimiri sciureus monkeys with Plasmodium falciparum merozoite surface protein-3 and glutamate-rich protein suggests that protection is related to antibody levels
-
L.J.Carvalho, S.G.Oliveira, M.Theisen, et al. Immunization of Saimiri sciureus monkeys with Plasmodium falciparum merozoite surface protein-3 and glutamate-rich protein suggests that protection is related to antibody levels. Scand J Immunol. 2004;59:363–372.
-
(2004)
Scand J Immunol
, vol.59
, pp. 363-372
-
-
Carvalho, L.J.1
Oliveira, S.G.2
Theisen, M.3
-
76
-
-
84895512540
-
Using the PfEMP1 head structure binding motif to deal a blow at severe malaria
-
M.E.Patarroyo, M.P.Alba, H.Curtidor, et al. Using the PfEMP1 head structure binding motif to deal a blow at severe malaria. PLoS One. 2014;9:e88420.
-
(2014)
PLoS One
, vol.9
, pp. e88420
-
-
Patarroyo, M.E.1
Alba, M.P.2
Curtidor, H.3
-
77
-
-
84891084707
-
Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5
-
A.D.Douglas, A.R.Williams, E.Knuepfer, et al. Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5. J Immunol. 2014;192:245–258.
-
(2014)
J Immunol
, vol.192
, pp. 245-258
-
-
Douglas, A.D.1
Williams, A.R.2
Knuepfer, E.3
-
78
-
-
0035450174
-
Are trials in New World monkeys on the critical path for blood-stage malaria vaccine development?
-
A.W.Stowers, L.H.Miller. Are trials in New World monkeys on the critical path for blood-stage malaria vaccine development? Trends Parasitol. 2001;17:415–419.
-
(2001)
Trends Parasitol
, vol.17
, pp. 415-419
-
-
Stowers, A.W.1
Miller, L.H.2
-
79
-
-
0037021395
-
Aotus monkeys: their great value for anti-malaria vaccines and drug testing
-
S.Herrera, B.L.Perlaza, A.Bonelo, et al. Aotus monkeys: their great value for anti-malaria vaccines and drug testing. Int J Parasitol. 2002;32:1625–1635.
-
(2002)
Int J Parasitol
, vol.32
, pp. 1625-1635
-
-
Herrera, S.1
Perlaza, B.L.2
Bonelo, A.3
-
80
-
-
0028787999
-
Safety, immunogenicity, and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults
-
D.Sturchler, R.Berger, C.Rudin, et al. Safety, immunogenicity, and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults. Am J Trop Med Hyg. 1995;53:423–431.
-
(1995)
Am J Trop Med Hyg
, vol.53
, pp. 423-431
-
-
Sturchler, D.1
Berger, R.2
Rudin, C.3
-
81
-
-
17344363385
-
Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria
-
C.F.Ockenhouse, P.F.Sun, D.E.Lanar, et al. Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J Infect Dis. 1998;177:1664–1673.
-
(1998)
J Infect Dis
, vol.177
, pp. 1664-1673
-
-
Ockenhouse, C.F.1
Sun, P.F.2
Lanar, D.E.3
-
82
-
-
80053910021
-
Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults
-
M.Sedegah, C.Tamminga, S.McGrath, et al. Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults. PLoS One. 2011;6:e24586.
-
(2011)
PLoS One
, vol.6
, pp. e24586
-
-
Sedegah, M.1
Tamminga, C.2
McGrath, S.3
-
83
-
-
42949156106
-
Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial
-
F.M.Thompson, D.W.Porter, S.L.Okitsu, et al. Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial. PLoS One. 2008;3:e1493.
-
(2008)
PLoS One
, vol.3
, pp. e1493
-
-
Thompson, F.M.1
Porter, D.W.2
Okitsu, S.L.3
-
84
-
-
84879105006
-
Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection
-
C.Tamminga, M.Sedegah, S.Maiolatesi, et al. Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection. Hum Vaccin Immunother. 2013;9:2165–2177.
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 2165-2177
-
-
Tamminga, C.1
Sedegah, M.2
Maiolatesi, S.3
-
85
-
-
84870602529
-
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans
-
S.H.Sheehy, C.J.Duncan, S.C.Elias, et al. ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. Mol Ther. 2012;20:2355–2368.
-
(2012)
Mol Ther
, vol.20
, pp. 2355-2368
-
-
Sheehy, S.H.1
Duncan, C.J.2
Elias, S.C.3
-
86
-
-
0034001440
-
Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers
-
G.Lawrence, Q.Q.Cheng, C.Reed, et al. Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers. Vaccine. 2000;18:1925–1931.
-
(2000)
Vaccine
, vol.18
, pp. 1925-1931
-
-
Lawrence, G.1
Cheng, Q.Q.2
Reed, C.3
-
87
-
-
78650598833
-
Experimental human challenge infections can accelerate clinical malaria vaccine development
-
R.W.Sauerwein, M.Roestenberg, V.S.Moorthy. Experimental human challenge infections can accelerate clinical malaria vaccine development. Nat Rev Immunol. 2010;11:57–64.
-
(2010)
Nat Rev Immunol
, vol.11
, pp. 57-64
-
-
Sauerwein, R.W.1
Roestenberg, M.2
Moorthy, V.S.3
-
88
-
-
84867860814
-
Experimentally induced blood stage malaria infection as a tool for clinical research
-
C.R.Engwerda, G.Minigo, F.H.Amante, et al. Experimentally induced blood stage malaria infection as a tool for clinical research. Trends Parasitol. 2012;28:515–521.
-
(2012)
Trends Parasitol
, vol.28
, pp. 515-521
-
-
Engwerda, C.R.1
Minigo, G.2
Amante, F.H.3
-
89
-
-
84884602417
-
Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccines
-
S.H.Sheehy, A.D.Douglas, S.J.Draper. Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccines. Hum Vaccin Immunother. 2013;9:1831–1840.
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 1831-1840
-
-
Sheehy, S.H.1
Douglas, A.D.2
Draper, S.J.3
-
90
-
-
84876079850
-
NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections
-
A.C.Teirlinck, M.Roestenberg, M.Van De Vegte-Bolmer, et al. NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections. J Infect Dis. 2012;207:656–660.
-
(2012)
J Infect Dis
, vol.207
, pp. 656-660
-
-
Teirlinck, A.C.1
Roestenberg, M.2
Van De Vegte-Bolmer, M.3
-
91
-
-
84927924779
-
Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines
-
D.I.Stanisic, X.Q.Liu, S.L.De, et al. Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines. Malar J. 2015;14:143.
-
(2015)
Malar J
, vol.14
, pp. 143
-
-
Stanisic, D.I.1
Liu, X.Q.2
De, S.L.3
-
92
-
-
84927909866
-
Modeling malaria in humanized mice: opportunities and challenges
-
E.Siu, A.Ploss. Modeling malaria in humanized mice: opportunities and challenges. Ann N Y Acad Sci. 2015;1342:29–36.
-
(2015)
Ann N Y Acad Sci
, vol.1342
, pp. 29-36
-
-
Siu, E.1
Ploss, A.2
-
93
-
-
84893342036
-
Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells
-
Q.Chen, A.Amaladoss, W.Ye, et al. Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells. Proc Natl Acad Sci U S A. 2014;111:1479–1484.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 1479-1484
-
-
Chen, Q.1
Amaladoss, A.2
Ye, W.3
-
94
-
-
84908113366
-
Humanized HLA-DR4.RagKO.IL2RgammacKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria
-
W.Wijayalath, S.Majji, E.F.Villasante, et al. Humanized HLA-DR4.RagKO.IL2RgammacKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria. Malar J. 2014;13:386.
-
(2014)
Malar J
, vol.13
, pp. 386
-
-
Wijayalath, W.1
Majji, S.2
Villasante, E.F.3
-
95
-
-
84952637954
-
Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria
-
pii: S0022-1759(15)30047-8
-
J.Huang, X.Li, J.G.Coelho-Dos-Reis, et al. Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria. J Immunol Methods. 2015 pii: S0022-1759(15)30047-8. doi:10.1016/j.jim.2015.09.005.
-
(2015)
J Immunol Methods
-
-
Huang, J.1
Li, X.2
Coelho-Dos-Reis, J.G.3
-
96
-
-
0037086437
-
A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea
-
B.Genton, I.Betuela, I.Felger, et al. A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea. J Infect Dis. 2002;185:820–827.•• The first phase II blood-stage vaccine trial which showed a strain-specific efficacy in the field.
-
(2002)
J Infect Dis
, vol.185
, pp. 820-827
-
-
Genton, B.1
Betuela, I.2
Felger, I.3
-
97
-
-
80052857926
-
A field trial to assess a blood-stage malaria vaccine
-
M.A.Thera, O.K.Doumbo, D.Coulibaly, et al. A field trial to assess a blood-stage malaria vaccine. N Engl J Med. 2011;365:1004–1013.•• The phase II blood-stage vaccine trial which showed a strain-specific protective efficacy in the field.
-
(2011)
N Engl J Med
, vol.365
, pp. 1004-1013
-
-
Thera, M.A.1
Doumbo, O.K.2
Coulibaly, D.3
-
98
-
-
80052844191
-
Protection against malaria by MSP3 candidate vaccine
-
S.B.Sirima, S.Cousens, P.Druilhe. Protection against malaria by MSP3 candidate vaccine. N Engl J Med. 2011;365:1062–1064.• A phase I blood-stage vaccine trial which showed a significant efficacy in the field.
-
(2011)
N Engl J Med
, vol.365
, pp. 1062-1064
-
-
Sirima, S.B.1
Cousens, S.2
Druilhe, P.3
-
99
-
-
84878407002
-
Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36
-
N.M.Palacpac, E.Ntege, A.Yeka, et al. Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36. PLoS One. 2013;8:e64073.• A phase I blood-stage vaccine trial which showed a significant efficacy in the field.
-
(2013)
PLoS One
, vol.8
, pp. e64073
-
-
Palacpac, N.M.1
Ntege, E.2
Yeka, A.3
-
100
-
-
84975144725
-
-
Available from:, Oct
-
WHO. Malaria rainbow tables; [cited 2015 Oct23]. Available from: http://www.who.int/immunization/research/development/Rainbow_tables/en/
-
Malaria rainbow tables
-
-
-
101
-
-
84878653016
-
-
Available from:, Oct
-
ClinicalTrial.gov; [cited 2015 Oct23]. Available from: https://clinicaltrials.gov/
-
ClinicalTrial.gov
-
-
-
102
-
-
84894187377
-
Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in Malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial
-
M.B.Laurens, M.A.Thera, D.Coulibaly, et al. Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in Malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial. PLoS One. 2013;8:e79323.
-
(2013)
PLoS One
, vol.8
, pp. e79323
-
-
Laurens, M.B.1
Thera, M.A.2
Coulibaly, D.3
-
103
-
-
67349273039
-
A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali
-
I.Sagara, A.Dicko, R.D.Ellis, et al. A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali. Vaccine. 2009;27:3090–3098.
-
(2009)
Vaccine
, vol.27
, pp. 3090-3098
-
-
Sagara, I.1
Dicko, A.2
Ellis, R.D.3
-
104
-
-
77953673075
-
Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine
-
A.Ouattara, J.Mu, S.Takala-Harrison, et al. Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine. Malar J. 2010;9:175.
-
(2010)
Malar J
, vol.9
, pp. 175
-
-
Ouattara, A.1
Mu, J.2
Takala-Harrison, S.3
-
105
-
-
51449101218
-
Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria
-
G.E.Mullen, R.D.Ellis, K.Miura, et al. Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria. PLoS One. 2008;3:e2940.
-
(2008)
PLoS One
, vol.3
, pp. e2940
-
-
Mullen, G.E.1
Ellis, R.D.2
Miura, K.3
-
106
-
-
84870781832
-
Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria
-
D.R.Drew, A.N.Hodder, D.W.Wilson, et al. Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria. PLoS One. 2012;7:e51023.
-
(2012)
PLoS One
, vol.7
, pp. e51023
-
-
Drew, D.R.1
Hodder, A.N.2
Wilson, D.W.3
-
107
-
-
84892864301
-
Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1
-
S.Dutta, L.S.Dlugosz, D.R.Drew, et al. Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1. PLoS Pathog. 2013;9:e1003840.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003840
-
-
Dutta, S.1
Dlugosz, L.S.2
Drew, D.R.3
-
108
-
-
84877804342
-
Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1
-
K.Miura, R.Herrera, A.Diouf, et al. Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1. Infect Immun. 2013;81:1491–1501.
-
(2013)
Infect Immun
, vol.81
, pp. 1491-1501
-
-
Miura, K.1
Herrera, R.2
Diouf, A.3
-
109
-
-
79851516179
-
Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits
-
K.A.Kusi, B.W.Faber, M.Van Der Eijk, et al. Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits. Malar J. 2011;10:40.
-
(2011)
Malar J
, vol.10
, pp. 40
-
-
Kusi, K.A.1
Faber, B.W.2
Van Der Eijk, M.3
-
110
-
-
79959776666
-
Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HTTM and Montanide ISA 51 in rhesus macaques
-
K.A.Kusi, E.J.Remarque, V.Riasat, et al. Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HTTM and Montanide ISA 51 in rhesus macaques. Malar J. 2011;10:182.
-
(2011)
Malar J
, vol.10
, pp. 182
-
-
Kusi, K.A.1
Remarque, E.J.2
Riasat, V.3
-
111
-
-
84907959194
-
Use of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1
-
K.S.Harris, C.G.Adda, M.Khore, et al. Use of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1. Infect Immun. 2014;82:4707–4717.
-
(2014)
Infect Immun
, vol.82
, pp. 4707-4717
-
-
Harris, K.S.1
Adda, C.G.2
Khore, M.3
-
112
-
-
77952007992
-
Interaction between Plasmodium falciparum apical membrane antigen 1 and the Rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites
-
D.Richard, C.A.Macraild, D.T.Riglar, et al. Interaction between Plasmodium falciparum apical membrane antigen 1 and the Rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites. J Biol Chem. 2010;285:14815–14822.
-
(2010)
J Biol Chem
, vol.285
, pp. 14815-14822
-
-
Richard, D.1
Macraild, C.A.2
Riglar, D.T.3
-
113
-
-
84904288773
-
Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria
-
P.Srinivasan, E.Ekanem, A.Diouf, et al. Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria. Proc Natl Acad Sci U S A. 2014;111:10311–10316.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 10311-10316
-
-
Srinivasan, P.1
Ekanem, E.2
Diouf, A.3
-
114
-
-
58549088281
-
Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure
-
C.W.Tsai, P.F.Duggan, A.J.Jin, et al. Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure. Mol Biochem Parasitol. 2009;164:45–56.
-
(2009)
Mol Biochem Parasitol
, vol.164
, pp. 45-56
-
-
Tsai, C.W.1
Duggan, P.F.2
Jin, A.J.3
-
115
-
-
28444478057
-
Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen
-
R.Audran, M.Cachat, F.Lurati, et al. Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen. Infect Immun. 2005;73:8017–8026.
-
(2005)
Infect Immun
, vol.73
, pp. 8017-8026
-
-
Audran, R.1
Cachat, M.2
Lurati, F.3
-
116
-
-
84880225221
-
The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria-endemic and non-endemic areas
-
M.P.Jepsen, P.S.Jogdand, S.K.Singh, et al. The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria-endemic and non-endemic areas. J Infect Dis. 2013;208:479–488.
-
(2013)
J Infect Dis
, vol.208
, pp. 479-488
-
-
Jepsen, M.P.1
Jogdand, P.S.2
Singh, S.K.3
-
117
-
-
70350786394
-
Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate
-
M.Esen, P.G.Kremsner, R.Schleucher, et al. Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate. Vaccine. 2009;27:6862–6868.
-
(2009)
Vaccine
, vol.27
, pp. 6862-6868
-
-
Esen, M.1
Kremsner, P.G.2
Schleucher, R.3
-
118
-
-
77956481961
-
Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambarene, Gabon
-
B.Mordmuller, K.Szywon, B.Greutelaers, et al. Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambarene, Gabon. Vaccine. 2010;28:6698–6703.
-
(2010)
Vaccine
, vol.28
, pp. 6698-6703
-
-
Mordmuller, B.1
Szywon, K.2
Greutelaers, B.3
-
119
-
-
79960872123
-
A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children
-
S.Belard, S.Issifou, A.B.Hounkpatin, et al. A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children. PLoS One. 2011;6:e22525.
-
(2011)
PLoS One
, vol.6
, pp. e22525
-
-
Belard, S.1
Issifou, S.2
Hounkpatin, A.B.3
-
120
-
-
77955329010
-
Evidences of protection against blood-stage infection of Plasmodium falciparum by the novel protein vaccine SE36
-
T.Horii, H.Shirai, L.Jie, et al. Evidences of protection against blood-stage infection of Plasmodium falciparum by the novel protein vaccine SE36. Parasitol Int. 2010;59:380–386.
-
(2010)
Parasitol Int
, vol.59
, pp. 380-386
-
-
Horii, T.1
Shirai, H.2
Jie, L.3
-
121
-
-
19944369747
-
The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasites
-
C.A.Darko, E.Angov, W.E.Collins, et al. The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasites. Infect Immun. 2005;73:287–297.
-
(2005)
Infect Immun
, vol.73
, pp. 287-297
-
-
Darko, C.A.1
Angov, E.2
Collins, W.E.3
-
122
-
-
50949124044
-
Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses
-
J.A.Lyon, E.Angov, M.P.Fay, et al. Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses. PLoS One. 2008;3:e2830.
-
(2008)
PLoS One
, vol.3
, pp. e2830
-
-
Lyon, J.A.1
Angov, E.2
Fay, M.P.3
-
123
-
-
61849177531
-
Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya
-
B.R.Ogutu, O.J.Apollo, D.McKinney, et al. Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya. PLoS One. 2009;4:e4708.
-
(2009)
PLoS One
, vol.4
, pp. e4708
-
-
Ogutu, B.R.1
Apollo, O.J.2
McKinney, D.3
-
124
-
-
84883799054
-
Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum
-
J.Healer, J.K.Thompson, D.T.Riglar, et al. Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum. PLoS One. 2013;8:e72504.
-
(2013)
PLoS One
, vol.8
, pp. e72504
-
-
Healer, J.1
Thompson, J.K.2
Riglar, D.T.3
-
125
-
-
34047147102
-
Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania
-
A.K.Bei, C.D.Membi, J.C.Rayner, et al. Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania. Mol Biochem Parasitol. 2007;153:66–71.
-
(2007)
Mol Biochem Parasitol
, vol.153
, pp. 66-71
-
-
Bei, A.K.1
Membi, C.D.2
Rayner, J.C.3
-
126
-
-
39849106625
-
Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif
-
V.Villard, G.W.Agak, G.Frank, et al. Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif. PLoS One. 2007;2:e645.
-
(2007)
PLoS One
, vol.2
, pp. e645
-
-
Villard, V.1
Agak, G.W.2
Frank, G.3
-
127
-
-
84867303317
-
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1
-
C.Kulangara, S.Luedin, O.Dietz, et al. Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1. PLoS One. 2012;7:e46112.
-
(2012)
PLoS One
, vol.7
, pp. e46112
-
-
Kulangara, C.1
Luedin, S.2
Dietz, O.3
-
128
-
-
72449167895
-
Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage associated P. falciparum protein PFF0165c
-
S.Olugbile, C.Kulangara, G.Bang, et al. Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage associated P. falciparum protein PFF0165c. Infect Immun. 2009;77:5701–5709.
-
(2009)
Infect Immun
, vol.77
, pp. 5701-5709
-
-
Olugbile, S.1
Kulangara, C.2
Bang, G.3
-
129
-
-
84455194899
-
The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody
-
A.D.Douglas, A.R.Williams, J.J.Illingworth, et al. The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody. Nat Commun. 2011;2:601.
-
(2011)
Nat Commun
, vol.2
, pp. 601
-
-
Douglas, A.D.1
Williams, A.R.2
Illingworth, J.J.3
-
130
-
-
84894289219
-
Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria
-
T.M.Tran, A.Ongoiba, J.Coursen, et al. Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria. J Infect Dis. 2014;209:789–798.
-
(2014)
J Infect Dis
, vol.209
, pp. 789-798
-
-
Tran, T.M.1
Ongoiba, A.2
Coursen, J.3
-
131
-
-
84888604265
-
Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans
-
S.D.Patel, A.D.Ahouidi, A.K.Bei, et al. Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans. J Infect Dis. 2013;208:1679–1687.
-
(2013)
J Infect Dis
, vol.208
, pp. 1679-1687
-
-
Patel, S.D.1
Ahouidi, A.D.2
Bei, A.K.3
-
132
-
-
84871375692
-
A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants
-
L.Y.Bustamante, S.J.Bartholdson, C.Crosnier, et al. A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants. Vaccine. 2013;31:373–379.
-
(2013)
Vaccine
, vol.31
, pp. 373-379
-
-
Bustamante, L.Y.1
Bartholdson, S.J.2
Crosnier, C.3
-
133
-
-
84920932154
-
A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in Aotus monkeys
-
A.D.Douglas, G.C.Baldeviano, C.M.Lucas, et al. A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in Aotus monkeys. Cell Host Microbe. 2015;17:130–139.
-
(2015)
Cell Host Microbe
, vol.17
, pp. 130-139
-
-
Douglas, A.D.1
Baldeviano, G.C.2
Lucas, C.M.3
-
134
-
-
80053440948
-
An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum
-
L.Chen, S.Lopaticki, D.T.Riglar, et al. An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum. PLoS Pathog. 2011;7:e1002199.
-
(2011)
PLoS Pathog
, vol.7
, pp. e1002199
-
-
Chen, L.1
Lopaticki, S.2
Riglar, D.T.3
-
135
-
-
84921782696
-
Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion
-
K.S.Reddy, E.Amlabu, A.K.Pandey, et al. Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion. Proc Natl Acad Sci U S A. 2015;112:1179–1184.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 1179-1184
-
-
Reddy, K.S.1
Amlabu, E.2
Pandey, A.K.3
-
136
-
-
84870778753
-
Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens
-
A.R.Williams, A.D.Douglas, K.Miura, et al. Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens. PLoS Pathog. 2012;8:e1002991.
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002991
-
-
Williams, A.R.1
Douglas, A.D.2
Miura, K.3
-
137
-
-
84890825277
-
Bacterially expressed full-length recombinant Plasmodium falciparum RH5 protein binds erythrocytes and elicits potent strain-transcending parasite-neutralizing antibodies
-
K.S.Reddy, A.K.Pandey, H.Singh, et al. Bacterially expressed full-length recombinant Plasmodium falciparum RH5 protein binds erythrocytes and elicits potent strain-transcending parasite-neutralizing antibodies. Infect Immun. 2014;82:152–164.
-
(2014)
Infect Immun
, vol.82
, pp. 152-164
-
-
Reddy, K.S.1
Pandey, A.K.2
Singh, H.3
-
138
-
-
84880106192
-
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development
-
J.S.Richards, T.U.Arumugam, L.Reiling, et al. Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development. J Immunol. 2013;191:795–809.
-
(2013)
J Immunol
, vol.191
, pp. 795-809
-
-
Richards, J.S.1
Arumugam, T.U.2
Reiling, L.3
-
139
-
-
84907968685
-
New antigens for a multicomponent blood-stage malaria vaccine
-
F.H.Osier, M.J.Mackinnon, C.Crosnier, et al. New antigens for a multicomponent blood-stage malaria vaccine. Sci Transl Med. 2014;6:247ra102.
-
(2014)
Sci Transl Med
, vol.6
, pp. 247ra102
-
-
Osier, F.H.1
Mackinnon, M.J.2
Crosnier, C.3
-
140
-
-
84901217934
-
Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection
-
D.K.Raj, C.P.Nixon, C.E.Nixon, et al. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection. Science. 2014;344:871–877.
-
(2014)
Science
, vol.344
, pp. 871-877
-
-
Raj, D.K.1
Nixon, C.P.2
Nixon, C.E.3
-
141
-
-
0029894462
-
Plasmodium falciparum: differential parasite growth inhibition mediated by antibodies to the antigens Pf332 and Pf155/RESA
-
N.Ahlborg, J.Iqbal, L.Bjork, et al. Plasmodium falciparum: differential parasite growth inhibition mediated by antibodies to the antigens Pf332 and Pf155/RESA. Exp Parasitol. 1996;82:155–163.
-
(1996)
Exp Parasitol
, vol.82
, pp. 155-163
-
-
Ahlborg, N.1
Iqbal, J.2
Bjork, L.3
-
142
-
-
84858597727
-
Pf332-C231-reactive antibodies affect growth and development of intra-erythrocytic Plasmodium falciparum parasites
-
H.A.Balogun, N.W.Awah, S.E.Farouk, et al. Pf332-C231-reactive antibodies affect growth and development of intra-erythrocytic Plasmodium falciparum parasites. Vaccine. 2011;30:21–28.
-
(2011)
Vaccine
, vol.30
, pp. 21-28
-
-
Balogun, H.A.1
Awah, N.W.2
Farouk, S.E.3
-
143
-
-
80052833040
-
The antibody response to Plasmodium falciparum merozoite surface protein 4: comparative assessment of specificity and growth inhibitory antibody activity to infection-acquired and immunization-induced epitopes
-
H.D.De Silva, S.Saleh, S.Kovacevic, et al. The antibody response to Plasmodium falciparum merozoite surface protein 4: comparative assessment of specificity and growth inhibitory antibody activity to infection-acquired and immunization-induced epitopes. Malar J. 2011;10:266.
-
(2011)
Malar J
, vol.10
, pp. 266
-
-
De Silva, H.D.1
Saleh, S.2
Kovacevic, S.3
-
144
-
-
84928781792
-
PfRON3 is an erythrocyte-binding protein and a potential blood-stage vaccine candidate antigen
-
X.Zhao, Z.Chang, Z.Tu, et al. PfRON3 is an erythrocyte-binding protein and a potential blood-stage vaccine candidate antigen. Malar J. 2014;13:490.
-
(2014)
Malar J
, vol.13
, pp. 490
-
-
Zhao, X.1
Chang, Z.2
Tu, Z.3
-
145
-
-
80855140147
-
Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen
-
T.U.Arumugam, S.Takeo, T.Yamasaki, et al. Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen. Infect Immun. 2011;79:4523–4532.
-
(2011)
Infect Immun
, vol.79
, pp. 4523-4532
-
-
Arumugam, T.U.1
Takeo, S.2
Yamasaki, T.3
-
146
-
-
84862807387
-
Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells
-
X.Li, M.Marinkovic, C.Russo, et al. Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells. Mol Biochem Parasitol. 2012;183:23–31.
-
(2012)
Mol Biochem Parasitol
, vol.183
, pp. 23-31
-
-
Li, X.1
Marinkovic, M.2
Russo, C.3
-
147
-
-
84857196017
-
Antibodies against a Plasmodium falciparum antigen PfMSPDBL1 inhibit merozoite invasion into human erythrocytes
-
H.Sakamoto, S.Takeo, A.G.Maier, et al. Antibodies against a Plasmodium falciparum antigen PfMSPDBL1 inhibit merozoite invasion into human erythrocytes. Vaccine. 2012;30:1972–1980.
-
(2012)
Vaccine
, vol.30
, pp. 1972-1980
-
-
Sakamoto, H.1
Takeo, S.2
Maier, A.G.3
-
148
-
-
84939477452
-
Antibodies to the Plasmodium falciparum proteins MSPDBL1 and MSPDBL2 opsonise merozoites, inhibit parasite growth and predict protection from clinical malaria
-
C.Y.Chiu, A.N.Hodder, C.S.Lin, et al. Antibodies to the Plasmodium falciparum proteins MSPDBL1 and MSPDBL2 opsonise merozoites, inhibit parasite growth and predict protection from clinical malaria. J Infect Dis. 2015;212:406–415.
-
(2015)
J Infect Dis
, vol.212
, pp. 406-415
-
-
Chiu, C.Y.1
Hodder, A.N.2
Lin, C.S.3
-
149
-
-
84886780001
-
RALP1 is a rhoptry-neck erythrocyte-binding protein of Plasmodium falciparum merozoite and a potential blood-stage vaccine candidate antigen
-
D.Ito, T.Hasegawa, K.Miura, et al. RALP1 is a rhoptry-neck erythrocyte-binding protein of Plasmodium falciparum merozoite and a potential blood-stage vaccine candidate antigen. Infect Immun. 2013;81:4290–4298.
-
(2013)
Infect Immun
, vol.81
, pp. 4290-4298
-
-
Ito, D.1
Hasegawa, T.2
Miura, K.3
-
150
-
-
84867134168
-
Phase 1 study in malaria naive adults of BSAM2/Alhydrogel(R)+CPG 7909, a blood stage vaccine against P. falciparum malaria
-
R.D.Ellis, Y.Wu, L.B.Martin, et al. Phase 1 study in malaria naive adults of BSAM2/Alhydrogel(R)+CPG 7909, a blood stage vaccine against P. falciparum malaria. PLoS One. 2012;7:e46094.
-
(2012)
PLoS One
, vol.7
, pp. e46094
-
-
Ellis, R.D.1
Wu, Y.2
Martin, L.B.3
-
151
-
-
84928721604
-
Phase I clinical trial of a recombinant blood stage vaccine candidate for Plasmodium falciparum malaria based on MSP1 and EBA175
-
C.E.Chitnis, P.Mukherjee, S.Mehta, et al. Phase I clinical trial of a recombinant blood stage vaccine candidate for Plasmodium falciparum malaria based on MSP1 and EBA175. PLoS One. 2015;10:e0117820.
-
(2015)
PLoS One
, vol.10
, pp. e0117820
-
-
Chitnis, C.E.1
Mukherjee, P.2
Mehta, S.3
-
152
-
-
79960668000
-
Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune adults & children
-
P.G.Cech, T.Aebi, M.S.Abdallah, et al. Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune adults & children. PLoS One. 2011;6:e22273.
-
(2011)
PLoS One
, vol.6
, pp. e22273
-
-
Cech, P.G.1
Aebi, T.2
Abdallah, M.S.3
-
153
-
-
84898539923
-
A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages
-
M.Theisen, W.Roeffen, S.K.Singh, et al. A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages. Vaccine. 2014;32:2623–2630.
-
(2014)
Vaccine
, vol.32
, pp. 2623-2630
-
-
Theisen, M.1
Roeffen, W.2
Singh, S.K.3
-
154
-
-
84940434878
-
Analysis of a multi-component multi-stage malaria vaccine candidate-tackling the cocktail challenge
-
A.Boes, H.Spiegel, N.Voepel, et al. Analysis of a multi-component multi-stage malaria vaccine candidate-tackling the cocktail challenge. PLoS One. 2015;10:e0131456.
-
(2015)
PLoS One
, vol.10
, pp. e0131456
-
-
Boes, A.1
Spiegel, H.2
Voepel, N.3
-
155
-
-
84943365709
-
The stage-specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi-stage vaccines
-
H.Spiegel, A.Boes, R.Kastilan, et al. The stage-specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi-stage vaccines. Biotechnol J. 2015;10:1651–1659.
-
(2015)
Biotechnol J
, vol.10
, pp. 1651-1659
-
-
Spiegel, H.1
Boes, A.2
Kastilan, R.3
-
156
-
-
84881245385
-
Cross-species malaria immunity induced by chemically attenuated parasites
-
M.F.Good, J.M.Reiman, I.B.Rodriguez, et al. Cross-species malaria immunity induced by chemically attenuated parasites. J Clin Invest. 2013;123:3353–3362.
-
(2013)
J Clin Invest
, vol.123
, pp. 3353-3362
-
-
Good, M.F.1
Reiman, J.M.2
Rodriguez, I.B.3
-
157
-
-
84884671436
-
Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine
-
R.A.Seder, L.-J.Chang, M.E.Enama, et al. Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine. Science. 2013;341:1359–1365.
-
(2013)
Science
, vol.341
, pp. 1359-1365
-
-
Seder, R.A.1
Chang, L.-J.2
Enama, M.E.3
-
158
-
-
70349485373
-
Five year safety and immunogenicity of GlaxoSmithKline’s candidate malaria vaccine RTS,S/AS02 following administration to semi-immune adult men living in a malaria-endemic region of The Gambia
-
K.Bojang, P.Milligan, M.Pinder, et al. Five year safety and immunogenicity of GlaxoSmithKline’s candidate malaria vaccine RTS,S/AS02 following administration to semi-immune adult men living in a malaria-endemic region of The Gambia. Hum Vaccin. 2009;5(4):242–247.
-
(2009)
Hum Vaccin
, vol.5
, Issue.4
, pp. 242-247
-
-
Bojang, K.1
Milligan, P.2
Pinder, M.3
-
159
-
-
67650699591
-
Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection
-
K.E.Kester, J.F.Cummings, O.Ofori-Anyinam, et al. Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection. J Infect Dis. 2009;200:337–346.
-
(2009)
J Infect Dis
, vol.200
, pp. 337-346
-
-
Kester, K.E.1
Cummings, J.F.2
Ofori-Anyinam, O.3
-
160
-
-
77049125460
-
Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults
-
M.A.Pierce, R.D.Ellis, L.B.Martin, et al. Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults. Vaccine. 2010;28:2236–2242.
-
(2010)
Vaccine
, vol.28
, pp. 2236-2242
-
-
Pierce, M.A.1
Ellis, R.D.2
Martin, L.B.3
-
161
-
-
34547647830
-
Structural basis of antigenic escape of a malaria vaccine candidate
-
S.Dutta, S.Y.Lee, A.H.Batchelor, et al. Structural basis of antigenic escape of a malaria vaccine candidate. Proc Natl Acad Sci U S A. 2007;104:12488–12493.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12488-12493
-
-
Dutta, S.1
Lee, S.Y.2
Batchelor, A.H.3
-
162
-
-
84911497016
-
Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies
-
K.E.Wright, K.A.Hjerrild, J.Bartlett, et al. Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature. 2014;515:427–430.
-
(2014)
Nature
, vol.515
, pp. 427-430
-
-
Wright, K.E.1
Hjerrild, K.A.2
Bartlett, J.3
-
163
-
-
84906933352
-
A malaria vaccine candidate based on an epitope of the Plasmodium falciparum RH5 protein
-
R.L.Ord, J.C.Caldeira, M.Rodriguez, et al. A malaria vaccine candidate based on an epitope of the Plasmodium falciparum RH5 protein. Malar J. 2014;13:326.
-
(2014)
Malar J
, vol.13
, pp. 326
-
-
Ord, R.L.1
Caldeira, J.C.2
Rodriguez, M.3
-
164
-
-
84941811406
-
Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model
-
S.Dunachie, T.Berthoud, A.V.Hill, et al. Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model. Vaccine. 2015;33:5321–5331.
-
(2015)
Vaccine
, vol.33
, pp. 5321-5331
-
-
Dunachie, S.1
Berthoud, T.2
Hill, A.V.3
|