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Volumn 10, Issue , 2011, Pages

Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT and Montanide ISA 51 in rhesus macaques

Author keywords

[No Author keywords available]

Indexed keywords

APICAL MEMBRANE ANTIGEN 1; COVACCINE HTTM; DIVERSITY COVERING VACCINE; HYBRID PROTEIN; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; MALARIA VACCINE; MONTANIDE ISA 51; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VACCINE; APICAL MEMBRANE ANTIGEN I, PLASMODIUM; DRUG DERIVATIVE; MANNITOL; MEMBRANE PROTEIN; OLEIC ACID; PARASITE ANTIGEN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; SUBUNIT VACCINE;

EID: 79959776666     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-10-182     Document Type: Article
Times cited : (35)

References (56)
  • 1
    • 0031804948 scopus 로고    scopus 로고
    • Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum
    • 9584096
    • Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. AA Escalante AA Lal FJ Ayala, Genetics 1998 149 189 202 9584096
    • (1998) Genetics , vol.149 , pp. 189-202
    • Escalante, A.A.1    Lal, A.A.2    Ayala, F.J.3
  • 2
    • 0034849136 scopus 로고    scopus 로고
    • Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene
    • Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene. SD Polley DJ Conway, Genetics 2001 158 1505 1512 11514442 (Pubitemid 32783136)
    • (2001) Genetics , vol.158 , Issue.4 , pp. 1505-1512
    • Policy, S.D.1    Conway, D.J.2
  • 4
    • 0025131748 scopus 로고
    • Analysis of variation in PF83, an erythrocytic merozoite vaccine candidate antigen of Plasmodium falciparum
    • DOI 10.1016/0166-6851(90)90172-I
    • Analysis of variation in PF83, an erythrocytic merozoite vaccine candidate antigen of Plasmodium falciparum. AW Thomas AP Waters D Carr, Mol Biochem Parasitol 1990 42 285 287 10.1016/0166-6851(90)90172-I 2270110 (Pubitemid 20283955)
    • (1990) Molecular and Biochemical Parasitology , vol.42 , Issue.2 , pp. 285-287
    • Thomas, A.W.1    Waters, A.P.2    Carr, D.3
  • 5
    • 0028145547 scopus 로고
    • Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites
    • DOI 10.1016/0166-6851(94)90096-5
    • Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites. DL Narum AW Thomas, Mol Biochem Parasitol 1994 67 59 68 10.1016/0166-6851(94)90096- 5 7838184 (Pubitemid 24287311)
    • (1994) Molecular and Biochemical Parasitology , vol.67 , Issue.1 , pp. 59-68
    • Narum, D.L.1    Thomas, A.W.2
  • 6
    • 0141502116 scopus 로고    scopus 로고
    • Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development
    • DOI 10.1242/jcs.00665
    • Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. LH Bannister JM Hopkins AR Dluzewski G Margos IT Williams MJ Blackman CH Kocken AW Thomas GH Mitchell, J Cell Sci 2003 116 3825 3834 10.1242/jcs.00665 12902400 (Pubitemid 37185311)
    • (2003) Journal of Cell Science , vol.116 , Issue.18 , pp. 3825-3834
    • Bannister, L.H.1    Hopkins, J.M.2    Dluzewski, A.R.3    Margos, G.4    Williams, I.T.5    Blackman, M.J.6    Kocken, C.H.7    Thomas, A.W.8    Mitchell, G.H.9
  • 7
    • 0036784706 scopus 로고    scopus 로고
    • Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites
    • 10.1128/IAI.70.10.5751-5758.2002. 12228305
    • Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites. J Healer S Crawford S Ralph G McFadden AF Cowman, Infect Immun 2002 70 5751 5758 10.1128/IAI.70.10.5751-5758.2002 12228305
    • (2002) Infect Immun , vol.70 , pp. 5751-5758
    • Healer, J.1    Crawford, S.2    Ralph, S.3    McFadden, G.4    Cowman, A.F.5
  • 8
    • 0346251040 scopus 로고    scopus 로고
    • Apical Membrane Antigen 1, a Major Malaria Vaccine Candidate, Mediates the Close Attachment of Invasive Merozoites to Host Red Blood Cells
    • DOI 10.1128/IAI.72.1.154-158.2004
    • Apical membrane antigen 1, a major malaria vaccine candidate, mediates the close attachment of invasive merozoites to host red blood cells. GH Mitchell AW Thomas G Margos AR Dluzewski LH Bannister, Infect Immun 2004 72 154 158 10.1128/IAI.72.1.154-158.2004 14688092 (Pubitemid 38018172)
    • (2004) Infection and Immunity , vol.72 , Issue.1 , pp. 154-158
    • Mitchell, G.H.1    Thomas, A.W.2    Margos, G.3    Dluzewski, A.R.4    Bannister, L.H.5
  • 9
    • 0033636201 scopus 로고    scopus 로고
    • Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species
    • 10.1046/j.1365-2958.2000.02175.x. 11115107
    • Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species. T Triglia J Healer SR Caruana AN Hodder RF Anders BS Crabb AF Cowman, Mol Microbiol 2000 38 706 718 10.1046/j.1365-2958.2000.02175.x 11115107
    • (2000) Mol Microbiol , vol.38 , pp. 706-718
    • Triglia, T.1    Healer, J.2    Caruana, S.R.3    Hodder, A.N.4    Anders, R.F.5    Crabb, B.S.6    Cowman, A.F.7
  • 10
    • 0035903097 scopus 로고    scopus 로고
    • Proteolytic Processing and Primary Structure of Plasmodium falciparum Apical Membrane Antigen-1
    • DOI 10.1074/jbc.M103076200
    • Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. SA Howell C Withers-Martinez CH Kocken AW Thomas MJ Blackman, J Biol Chem 2001 276 31311 31320 10.1074/jbc.M103076200 11399764 (Pubitemid 37385002)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.33 , pp. 31311-31320
    • Howell, S.A.1    Withers-Martinez, C.2    Kocken, C.H.M.3    Thomas, A.W.4    Blackman, M.J.5
  • 13
    • 0033958230 scopus 로고    scopus 로고
    • 19 across distantly related Plasmodium species
    • DOI 10.1038/71595
    • 19across distantly related Plasmodium species. RA O'Donnell A Saul AF Cowman BS Crabb, Nat Med 2000 6 91 95 10.1038/71595 10613831 (Pubitemid 30048533)
    • (2000) Nature Medicine , vol.6 , Issue.1 , pp. 91-95
    • O'Donnell, R.A.1    Saul, A.2    Cowman, A.F.3    Crabb, B.S.4
  • 14
    • 0032078828 scopus 로고    scopus 로고
    • Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen
    • 10.1016/S0166-6851(98)00010-3. 9657329
    • Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. SH Qari YP Shi IF Goldman BL Nahlen M Tibayrenc AA Lal, Mol Biochem Parasitol 1998 92 241 252 10.1016/S0166-6851(98)00010-3 9657329
    • (1998) Mol Biochem Parasitol , vol.92 , pp. 241-252
    • Qari, S.H.1    Shi, Y.P.2    Goldman, I.F.3    Nahlen, B.L.4    Tibayrenc, M.5    Lal, A.A.6
  • 15
    • 0029130016 scopus 로고
    • Plasmodium falciparum: Variations within the C-terminal region of merozoite surface antigen-1
    • 10.1006/expr.1995.1091. 7628566
    • Plasmodium falciparum: variations within the C-terminal region of merozoite surface antigen-1. R Tolle H Bujard JA Cooper, Exp Parasitol 1995 81 47 54 10.1006/expr.1995.1091 7628566
    • (1995) Exp Parasitol , vol.81 , pp. 47-54
    • Tolle, R.1    Bujard, H.2    Cooper, J.A.3
  • 17
    • 0026010023 scopus 로고
    • Processing of the Plasmodium falciparum major merozoite surface protein-1: Identification of a 33-kilodalton secondary processing product which is shed prior to erythrocyte invasion
    • 10.1016/0166-6851(91)90128-S. 1723148
    • Processing of the Plasmodium falciparum major merozoite surface protein-1: identification of a 33-kilodalton secondary processing product which is shed prior to erythrocyte invasion. MJ Blackman H Whittle AA Holder, Mol Biochem Parasitol 1991 49 35 44 10.1016/0166-6851(91)90128-S 1723148
    • (1991) Mol Biochem Parasitol , vol.49 , pp. 35-44
    • Blackman, M.J.1    Whittle, H.2    Holder, A.A.3
  • 18
    • 0023099227 scopus 로고
    • Processing of the precursor to the major merozoite surface antigens of Plasmodium falciparum
    • Processing of the precursor to the major merozoite surface antigens of Plasmodium falciparum. AA Holder JS Sandhu Y Hillman LS Davey SC Nicholls H Cooper MJ Lockyer, Parasitology 1987 94 Pt 2 199 208 3295686 (Pubitemid 17043460)
    • (1987) Parasitology , vol.94 , Issue.2 , pp. 199-208
    • Holder, A.A.1    Sandhu, J.S.2    Hillman, Y.3
  • 19
    • 0025310377 scopus 로고
    • A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies
    • DOI 10.1084/jem.172.1.379
    • A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies. MJ Blackman HG Heidrich S Donachie JS McBride AA Holder, J Exp Med 1990 172 379 382 10.1084/jem.172.1.379 1694225 (Pubitemid 20217284)
    • (1990) Journal of Experimental Medicine , vol.172 , Issue.1 , pp. 379-382
    • Blackman, M.J.1    Heidrich, H.-G.2    Donachie, S.3    McBride, J.S.4    Holder, A.A.5
  • 20
    • 0025989235 scopus 로고
    • Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains
    • 10.1016/0166-6851(91)90127-R. 1775158
    • Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains. MJ Blackman IT Ling SC Nicholls AA Holder, Mol Biochem Parasitol 1991 49 29 33 10.1016/0166-6851(91)90127-R 1775158
    • (1991) Mol Biochem Parasitol , vol.49 , pp. 29-33
    • Blackman, M.J.1    Ling, I.T.2    Nicholls, S.C.3    Holder, A.A.4
  • 21
    • 0031986201 scopus 로고    scopus 로고
    • Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi
    • DOI 10.1016/S0264-410X(97)88331-4, PII S0264410X97001783
    • Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. RF Anders PE Crewther S Edwards M Margetts ML Matthew B Pollock D Pye, Vaccine 1998 16 240 247 10.1016/S0264-410X(97)88331-4 9607037 (Pubitemid 27521005)
    • (1998) Vaccine , vol.16 , Issue.2-3 , pp. 240-247
    • Anders, R.F.1    Crewther, P.E.2    Edwards, S.3    Margetts, M.4    Matthew, M.L.S.M.5    Pollock, B.6    Pye, D.7
  • 23
    • 0035058431 scopus 로고    scopus 로고
    • Specificity of the protective antibody response to apical membrane antigen 1
    • DOI 10.1128/IAI.69.5.3286-3294.2001
    • Specificity of the protective antibody response to apical membrane antigen 1. AN Hodder PE Crewther RF Anders, Infect Immun 2001 69 3286 3294 10.1128/IAI.69.5.3286-3294.2001 11292751 (Pubitemid 32332227)
    • (2001) Infection and Immunity , vol.69 , Issue.5 , pp. 3286-3294
    • Hodder, A.N.1    Crewther, P.E.2    Anders, R.F.3
  • 25
    • 0034095455 scopus 로고    scopus 로고
    • Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection
    • DOI 10.1128/IAI.68.5.2899-2906.2000
    • Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection. DL Narum SA Ogun AW Thomas AA Holder, Infect Immun 2000 68 2899 2906 10.1128/IAI.68.5.2899-2906.2000 10768987 (Pubitemid 30253870)
    • (2000) Infection and Immunity , vol.68 , Issue.5 , pp. 2899-2906
    • Narum, D.L.1    Ogun, S.A.2    Thomas, A.W.3    Holder, A.A.4
  • 26
    • 33746645179 scopus 로고    scopus 로고
    • Immunity to recombinant Plasmodium falciparum merozoite surface protein 1 (MSP1): Protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity
    • DOI 10.1128/IAI.01679-05
    • Immunity to recombinant Plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity. S Singh K Miura H Zhou O Muratova B Keegan A Miles LB Martin AJ Saul LH Miller CA Long, Infect Immun 2006 74 4573 4580 10.1128/IAI.01679-05 16861644 (Pubitemid 44157244)
    • (2006) Infection and Immunity , vol.74 , Issue.8 , pp. 4573-4580
    • Singh, S.1    Miura, K.2    Zhou, H.3    Muratova, O.4    Keegan, B.5    Miles, A.6    Martin, L.B.7    Saul, A.J.8    Miller, L.H.9    Long, C.A.10
  • 27
    • 0036893441 scopus 로고    scopus 로고
    • Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria
    • DOI 10.1128/IAI.70.12.6961-6967.2002
    • Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria. AW Stowers MC Kennedy BP Keegan A Saul CA Long LH Miller, Infect Immun 2002 70 6961 6967 10.1128/IAI.70.12.6961-6967.2002 12438375 (Pubitemid 35387931)
    • (2002) Infection and Immunity , vol.70 , Issue.12 , pp. 6961-6967
    • Stowers, A.W.1    Kennedy, M.C.2    Keegan, B.P.3    Saul, A.4    Long, C.A.5    Miller, L.H.6
  • 28
    • 0028279254 scopus 로고
    • Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein
    • DOI 10.1084/jem.180.1.389
    • Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein. MJ Blackman TJ Scott-Finnigan S Shai AA Holder, J Exp Med 1994 180 389 393 10.1084/jem.180.1.389 7516416 (Pubitemid 24181090)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.1 , pp. 389-393
    • Blackman, M.J.1    Scott-Finnigan, T.J.2    Shai, S.3    Holder, A.A.4
  • 31
    • 0030017335 scopus 로고    scopus 로고
    • Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes
    • Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes. PE Crewther ML Matthew RH Flegg RF Anders, Infect Immun 1996 64 3310 3317 8757869 (Pubitemid 26256181)
    • (1996) Infection and Immunity , vol.64 , Issue.8 , pp. 3310-3317
    • Crewther, P.E.1    Matthew, M.L.S.M.2    Flegg, R.H.3    Anders, R.F.4
  • 32
    • 0036892213 scopus 로고    scopus 로고
    • In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): Production and activity of an AMA1 vaccine and generation of a multiallelic response
    • DOI 10.1128/IAI.70.12.6948-6960.2002
    • In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response. MC Kennedy J Wang Y Zhang AP Miles F Chitsaz A Saul CA Long LH Miller AW Stowers, Infect Immun 2002 70 6948 6960 10.1128/IAI.70.12. 6948-6960.2002 12438374 (Pubitemid 35387930)
    • (2002) Infection and Immunity , vol.70 , Issue.12 , pp. 6948-6960
    • Kennedy, M.C.1    Wang, J.2    Zhang, Y.3    Miles, A.P.4    Chitsaz, F.5    Saul, A.6    Long, C.A.7    Miller, L.H.8    Stowers, A.W.9
  • 33
    • 46249103583 scopus 로고    scopus 로고
    • A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits
    • 10.1128/IAI.00170-08. 18378635
    • A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits. EJ Remarque BW Faber CH Kocken AW Thomas, Infect Immun 2008 76 2660 2670 10.1128/IAI.00170-08 18378635
    • (2008) Infect Immun , vol.76 , pp. 2660-2670
    • Remarque, E.J.1    Faber, B.W.2    Kocken, C.H.3    Thomas, A.W.4
  • 34
    • 78149491347 scopus 로고    scopus 로고
    • Generation of humoral immune responses to multi-allele PfAMA1 vaccines; Effect of adjuvant and number of component alleles on the breadth of response
    • 10.1371/journal.pone.0015391. 21082025
    • Generation of humoral immune responses to multi-allele PfAMA1 vaccines; effect of adjuvant and number of component alleles on the breadth of response. KA Kusi BW Faber V Riasat AW Thomas CH Kocken EJ Remarque, PLoS ONE 2010 5 15391 10.1371/journal.pone.0015391 21082025
    • (2010) PLoS ONE , vol.5 , pp. 515391
    • Kusi, K.A.1    Faber, B.W.2    Riasat, V.3    Thomas, A.W.4    Kocken, C.H.5    Remarque, E.J.6
  • 35
    • 36749029317 scopus 로고    scopus 로고
    • Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein
    • DOI 10.1128/IAI.01804-06
    • Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1. BW Faber EJ Remarque WD Morgan CH Kocken AA Holder AW Thomas, Infect Immun 2007 75 5947 5955 10.1128/IAI.01804-06 17938224 (Pubitemid 350207835)
    • (2007) Infection and Immunity , vol.75 , Issue.12 , pp. 5947-5955
    • Faber, B.W.1    Remarque, E.J.2    Morgan, W.D.3    Kocken, C.H.M.4    Holder, A.A.5    Thomas, A.W.6
  • 36
    • 0037449076 scopus 로고    scopus 로고
    • Immunization against Plasmodium chabaudi malaria using combined formulations of apical membrane antigen-1 and merozoite surface protein-1
    • DOI 10.1016/S0264-410X(03)00026-4
    • Immunization against Plasmodium chabaudi malaria using combined formulations of apical membrane antigen-1 and merozoite surface protein-1. JM Burns jr PR Flaherty MM Romero WP Weidanz, Vaccine 2003 21 1843 1852 10.1016/S0264-410X(03)00026-4 12706668 (Pubitemid 36428774)
    • (2003) Vaccine , vol.21 , Issue.17-18 , pp. 1843-1852
    • Burns Jr., J.M.1    Flaherty, P.R.2    Romero, M.M.3    Weidanz, W.P.4
  • 38
    • 77949498908 scopus 로고    scopus 로고
    • Humoral immune response to mixed PfAMA1 alleles; Multivalent PfAMA1 vaccines induce broad specificity
    • 10.1371/journal.pone.0008110. 19956619
    • Humoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity. KA Kusi BW Faber AW Thomas EJ Remarque, PLoS ONE 2009 4 8110 10.1371/journal.pone.0008110 19956619
    • (2009) PLoS ONE , vol.4 , pp. 58110
    • Kusi, K.A.1    Faber, B.W.2    Thomas, A.W.3    Remarque, E.J.4
  • 39
    • 33846696164 scopus 로고    scopus 로고
    • A working group report chaired by Sir David Weatheall
    • The use of non-human primates in research. A working group report chaired by Sir David Weatheall, 2006 http://www.acmedsci.ac.uk/images/project/nhpdownl. pdf
    • (2006) The Use of Non-human Primates in Research
  • 40
    • 33344467685 scopus 로고    scopus 로고
    • Enhancement of functional antibody responses to AMA1-C1/Alhydrogel, a Plasmodium falciparum malaria vaccine, with CpG oligodeoxynucleotide
    • DOI 10.1016/j.vaccine.2005.12.034, PII S0264410X05012715
    • Enhancement of functional antibody responses to AMA1-C1/Alhydrogel, a Plasmodium falciparum malaria vaccine, with CpG oligodeoxynucleotide. GE Mullen BK Giersing O Ajose-Popoola HL Davis C Kothe H Zhou J Aebig G Dobrescu A Saul CA Long, Vaccine 2006 24 2497 2505 10.1016/j.vaccine.2005.12.034 16434128 (Pubitemid 43290379)
    • (2006) Vaccine , vol.24 , Issue.14 , pp. 2497-2505
    • Mullen, G.E.D.1    Giersing, B.K.2    Ajose-Popoola, O.3    Davis, H.L.4    Kothe, C.5    Zhou, H.6    Aebig, J.7    Dobrescu, G.8    Saul, A.9    Long, C.A.10
  • 44
    • 84905019120 scopus 로고    scopus 로고
    • Identifiers NCT00702221, NCT00895466, NCT01015703
    • Clinical trials registration database. http://www.clinicaltrials.gov Identifiers NCT00702221, NCT00895466, NCT01015703
    • Clinical Trials Registration Database
  • 45
    • 0037395150 scopus 로고    scopus 로고
    • Effects of the anaesthetic/tranquillizer treatments on selected plasma biochemical parameters in NZW rabbits
    • DOI 10.1258/00236770360563804
    • Effects of the anaesthetic/tranquillizer treatments on selected plasma biochemical parameters in NZW rabbits. A Gonzalez Gil JC Illera G Silvan M Illera, Laboratory Animals 2003 37 155 161 10.1258/00236770360563804 12689427 (Pubitemid 36470104)
    • (2003) Laboratory Animals , vol.37 , Issue.2 , pp. 155-161
    • Gonzalez Gil, A.1    Illera, J.C.2    Silvan, G.3    Illera, M.4
  • 46
    • 0024398050 scopus 로고
    • The effects of prolonged ketamine-xylazine intravenous infusion on arterial blood pH, blood gases, mean arterial blood pressure, heart and respiratory rates, rectal temperature and reflexes in the rabbit
    • The effects of prolonged ketamine-xylazine intravenous infusion on arterial blood pH, blood gases, mean arterial blood pressure, heart and respiratory rates, rectal temperature and reflexes in the rabbit. JD Wyatt RA Scott ME Richardson, Lab Anim Sci 1989 39 411 416 2530398 (Pubitemid 19225974)
    • (1989) Laboratory Animal Science , vol.39 , Issue.5 , pp. 411-416
    • Wyatt, J.D.1    Scott, R.A.W.2    Richardson, M.E.3
  • 50
    • 35348850079 scopus 로고    scopus 로고
    • Safety, antigenicity, and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus macaques (Macaca fascicularis)
    • DOI 10.1196/annals.1406.042, Coccidioidomycosis Sixth International Symposium
    • Safety, antigenicity, and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus macaques (Macaca fascicularis). SM Johnson NW Lerche D Pappagianis JL Yee JN Galgiani RF Hector, Ann N Y Acad Sci 2007 1111 290 300 10.1196/annals.1406.042 17347333 (Pubitemid 47573038)
    • (2007) Annals of the New York Academy of Sciences , vol.1111 , pp. 290-300
    • Johnson, S.M.1    Lerche, N.W.2    Pappagianis, D.3    Yee, J.L.4    Galgiani, J.N.5    Hector, R.F.6
  • 51
    • 77950628629 scopus 로고    scopus 로고
    • Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates
    • 10.1016/j.vaccine.2010.02.069. 20197134
    • Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates. Y Morera M Bequet-Romero M Ayala JC Velazco PP Perez JS Alba J Ancizar M Rodriguez K Cosme JV Gavilondo, Vaccine 2010 28 3453 3461 10.1016/j.vaccine.2010.02.069 20197134
    • (2010) Vaccine , vol.28 , pp. 3453-3461
    • Morera, Y.1    Bequet-Romero, M.2    Ayala, M.3    Velazco, J.C.4    Perez, P.P.5    Alba, J.S.6    Ancizar, J.7    Rodriguez, M.8    Cosme, K.9    Gavilondo, J.V.10
  • 52
    • 79952468617 scopus 로고    scopus 로고
    • Phase i safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51
    • 10.4269/ajtmh.2011.09-0516. 21292873
    • Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51. S Herrera OL Fernandez O Vera W Cardenas O Ramirez R Palacios M Chen-Mok G Corradin M Arevalo-Herrera, Am J Trop Med Hyg 2011 84 12 20 10.4269/ajtmh.2011. 09-0516 21292873
    • (2011) Am J Trop Med Hyg , vol.84 , pp. 12-20
    • Herrera, S.1    Fernandez, O.L.2    Vera, O.3    Cardenas, W.4    Ramirez, O.5    Palacios, R.6    Chen-Mok, M.7    Corradin, G.8    Arevalo-Herrera, M.9
  • 53
    • 2442626574 scopus 로고    scopus 로고
    • Fusion of Two Malaria Vaccine Candidate Antigens Enhances Product Yield, Immunogenicity, and Antibody-Mediated Inhibition of Parasite Growth in Vitro
    • Fusion of two malaria vaccine candidate antigens enhances product yield, immunogenicity, and antibody-mediated inhibition of parasite growth in vitro. W Pan D Huang Q Zhang L Qu D Zhang X Zhang X Xue F Qian, J Immunol 2004 172 6167 6174 15128804 (Pubitemid 38621222)
    • (2004) Journal of Immunology , vol.172 , Issue.10 , pp. 6167-6174
    • Pan, W.1    Huang, D.2    Zhang, Q.3    Qu, L.4    Zhang, D.5    Zhang, X.6    Xue, X.7    Qian, F.8
  • 56
    • 0034455753 scopus 로고    scopus 로고
    • Repeated infection of Aotus monkeys with Plasmodium falciparum induces protection against subsequent challenge with homologous and heterologous strains of parasite
    • Repeated infection of Aotus monkeys with Plasmodium falciparum induces protection against subsequent challenge with homologous and heterologous strains of parasite. TR Jones N Obaldia RA Gramzinski SL Hoffman, Am J Trop Med Hyg 2000 62 675 680 11304053 (Pubitemid 32281484)
    • (2000) American Journal of Tropical Medicine and Hygiene , vol.62 , Issue.6 , pp. 675-680
    • Jones, T.R.1    Obaldia III, N.2    Gramzinski, R.A.3    Hoffman, S.L.4


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