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Volumn 6, Issue 247, 2014, Pages

Malaria: New antigens for a multicomponent blood-stage malaria vaccine

Author keywords

[No Author keywords available]

Indexed keywords

AMA1 ANTIGEN; MALARIA VACCINE; MSP11 ANTIGEN; MSP2 ANTIGEN; MSP3 ANTIGEN; MSRP1 ANTIGEN; P41 ANTIGEN; PARASITE ANTIGEN; PF113 ANTIGEN; PF3D7 0606800 ANTIGEN; PF3D7 1136200 ANTIGEN; RHOPH3 ANTIGEN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MEROZOITE SURFACE PROTEIN 2, PLASMODIUM; MSP3 PROTEIN, PLASMODIUM FALCIPARUM (181-276); PEPTIDE FRAGMENT; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; RHOPTRY ASSOCIATED PROTEIN, PLASMODIUM;

EID: 84907968685     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3008705     Document Type: Article
Times cited : (133)

References (58)
  • 1
    • 45549097494 scopus 로고    scopus 로고
    • Immunity to malaria: More questions than answers
    • DOI 10.1038/ni.f.205, PII NI.F.205
    • J. Langhorne, F. M. Ndungu, A. M. Sponaas, K. Marsh, Immunity to malaria: More questions than answers. Nat. Immunol. 9, 725-732 (2008). (Pubitemid 351859155)
    • (2008) Nature Immunology , vol.9 , Issue.7 , pp. 725-732
    • Langhorne, J.1    Ndungu, F.M.2    Sponaas, A.-M.3    Marsh, K.4
  • 2
    • 8144224632 scopus 로고
    • Gamma-globulin and acquired immunity to human malaria
    • S. Cohen, I. McGregor, S. Carrington, Gamma-globulin and acquired immunity to human malaria. Nature 192, 733-737 (1961).
    • (1961) Nature , vol.192 , pp. 733-737
    • Cohen, S.1    McGregor, I.2    Carrington, S.3
  • 4
    • 75749098881 scopus 로고    scopus 로고
    • The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and metaanalysis
    • F. J. Fowkes, J. S. Richards, J. A. Simpson, J. G. Beeson, The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and metaanalysis. PLOS Med. 7, e1000218 (2010).
    • (2010) PLOS Med. , vol.7
    • Fowkes, F.J.1    Richards, J.S.2    Simpson, J.A.3    Beeson, J.G.4
  • 11
    • 0031986201 scopus 로고    scopus 로고
    • Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi
    • DOI 10.1016/S0264-410X(97)88331-4, PII S0264410X97001783
    • R. F. Anders, P. E. Crewther, S. Edwards, M. Margetts, M. L. Matthew, B. Pollock, D. Pye, Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine 16, 240-247 (1998). (Pubitemid 27521005)
    • (1998) Vaccine , vol.16 , Issue.2-3 , pp. 240-247
    • Anders, R.F.1    Crewther, P.E.2    Edwards, S.3    Margetts, M.4    Matthew, M.L.S.M.5    Pollock, B.6    Pye, D.7
  • 12
    • 84869114925 scopus 로고    scopus 로고
    • The cellular and molecular basis for malaria parasite invasion of the human red blood cell
    • A. F. Cowman, D. Berry, J. Baum, The cellular and molecular basis for malaria parasite invasion of the human red blood cell. J. Cell Biol. 198, 961-971 (2012).
    • (2012) J. Cell Biol. , vol.198 , pp. 961-971
    • Cowman, A.F.1    Berry, D.2    Baum, J.3
  • 13
  • 14
    • 33846156218 scopus 로고    scopus 로고
    • Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection
    • DOI 10.1086/509806
    • S. D. Polley, K. K. Tetteh, J. M. Lloyd, O. J. Akpogheneta, B. M. Greenwood, K. A. Bojang, D. J. Conway, Plasmodium falciparum merozoite surface protein 3 is a target of allelespecific immunity and alleles are maintained by natural selection. J. Infect. Dis. 195, 279-287 (2007). (Pubitemid 46080060)
    • (2007) Journal of Infectious Diseases , vol.195 , Issue.2 , pp. 279-287
    • Polley, S.D.1    Tetteh, K.K.A.2    Lloyd, J.M.3    Akpogheneta, O.J.4    Greenwood, B.M.5    Bojang, K.A.6    Conway, D.J.7
  • 15
    • 0028844321 scopus 로고
    • Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclass
    • R. R. Taylor, D. B. Smith, V. J. Robinson, J. S. McBride, E. M. Riley, Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclass. Infect. Immun. 63, 4382-4388 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 4382-4388
    • Taylor, R.R.1    Smith, D.B.2    Robinson, V.J.3    McBride, J.S.4    Riley, E.M.5
  • 17
    • 34447526390 scopus 로고    scopus 로고
    • Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3
    • DOI 10.1111/j.1365-3024.2007.00951.x
    • F. H. Osier, S. D. Polley, T. Mwangi, B. Lowe, D. J. Conway, K. Marsh, Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3. Parasite Immunol. 29, 387-394 (2007). (Pubitemid 47083924)
    • (2007) Parasite Immunology , vol.29 , Issue.8 , pp. 387-394
    • Osier, F.H.A.1    Polley, S.D.2    Mwangi, T.3    Lowe, B.4    Conway, D.J.5    Marsh, K.6
  • 19
    • 76749114386 scopus 로고    scopus 로고
    • Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria
    • F. H. Osier, L. M. Murungi, G. Fegan, J. Tuju, K. K. Tetteh, P. C. Bull, D. J. Conway, K. Marsh, Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria. Parasite Immunol. 32, 193-201 (2010).
    • (2010) Parasite Immunol. , vol.32 , pp. 193-201
    • Osier, F.H.1    Murungi, L.M.2    Fegan, G.3    Tuju, J.4    Tetteh, K.K.5    Bull, P.C.6    Conway, D.J.7    Marsh, K.8
  • 20
    • 33646144191 scopus 로고    scopus 로고
    • High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya
    • S. D. Polley, D. J. Conway, D. R. Cavanagh, J. S. McBride, B. S. Lowe, T. N. Williams, T. W. Mwangi, K. Marsh, High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya. Vaccine 24, 4233-4246 (2006).
    • (2006) Vaccine , vol.24 , pp. 4233-4246
    • Polley, S.D.1    Conway, D.J.2    Cavanagh, D.R.3    McBride, J.S.4    Lowe, B.S.5    Williams, T.N.6    Mwangi, T.W.7    Marsh, K.8
  • 21
    • 20844446443 scopus 로고    scopus 로고
    • Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria
    • DOI 10.1016/j.vaccine.2004.05.031, PII S0264410X04004438
    • S. D. Polley, T. Mwangi, C. H. Kocken, A. W. Thomas, S. Dutta, D. E. Lanar, E. Remarque, A. Ross, T. N. Williams, G. Mwambingu, B. Lowe, D. J. Conway, K. Marsh, Human antibodies to recombinant protein constructs of Plasmodium falciparum apical membrane antigen 1 (AMA1) and their associations with protection from malaria. Vaccine 23, 718-728 (2004). (Pubitemid 39473204)
    • (2004) Vaccine , vol.23 , Issue.5 , pp. 718-728
    • Polley, S.D.1    Mwangi, T.2    Kocken, C.H.M.3    Thomas, A.W.4    Dutta, S.5    Lanar, D.E.6    Remarque, E.7    Ross, A.8    Williams, T.N.9    Mwambingu, G.10    Lowe, B.11    Conway, D.J.12    Marsh, K.13
  • 22
    • 84884364582 scopus 로고    scopus 로고
    • Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity
    • K. K. Tetteh, F. H. Osier, A. Salanti, G. Kamuyu, L. Drought, M. Failly, C. Martin, K. Marsh, D. J. Conway, Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity. Infect. Immun. 81, 3835-3842 (2013).
    • (2013) Infect. Immun. , vol.81 , pp. 3835-3842
    • Tetteh, K.K.1    Osier, F.H.2    Salanti, A.3    Kamuyu, G.4    Drought, L.5    Failly, M.6    Martin, C.7    Marsh, K.8    Conway, D.J.9
  • 29
    • 84871375692 scopus 로고    scopus 로고
    • A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants
    • L. Y. Bustamante, S. J. Bartholdson, C. Crosnier, M. G. Campos, M. Wanaguru, C. Nguon, D. P. Kwiatkowski, G. J. Wright, J. C. Rayner, A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants. Vaccine 31, 373-379 (2013).
    • (2013) Vaccine , vol.31 , pp. 373-379
    • Bustamante, L.Y.1    Bartholdson, S.J.2    Crosnier, C.3    Campos, M.G.4    Wanaguru, M.5    Nguon, C.6    Kwiatkowski, D.P.7    Wright, G.J.8    Rayner, J.C.9
  • 33
    • 84881546402 scopus 로고    scopus 로고
    • A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria
    • L. M. Murungi, G. Kamuyu, B. Lowe, P. Bejon, M. Theisen, S. M. Kinyanjui, K. Marsh, F. H. Osier, A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria. Vaccine 31, 3936-3942 (2013).
    • (2013) Vaccine , vol.31 , pp. 3936-3942
    • Murungi, L.M.1    Kamuyu, G.2    Lowe, B.3    Bejon, P.4    Theisen, M.5    Kinyanjui, S.M.6    Marsh, K.7    Osier, F.H.8
  • 34
    • 84887908446 scopus 로고    scopus 로고
    • Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria
    • J. Rono, F. H. Osier, D. Olsson, S. Montgomery, L. Mhoja, I. Rooth, K. Marsh, A. Färnert, Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria. Clin. Infect. Dis. 57, 1409-1416 (2013).
    • (2013) Clin. Infect. Dis. , vol.57 , pp. 1409-1416
    • Rono, J.1    Osier, F.H.2    Olsson, D.3    Montgomery, S.4    Mhoja, L.5    Rooth, I.6    Marsh, K.7    Färnert, A.8
  • 35
    • 9644289645 scopus 로고    scopus 로고
    • Natural antibody response to Plasmodium falciparum Exp-1, MSP-3 and GLURP long synthetic peptides and association with protection
    • DOI 10.1111/j.0141-9838.2004.00705.x
    • V. Meraldi, I. Nebié, A. B. Tiono, D. Diallo, E. Sanogo, M. Theisen, P. Druilhe, G. Corradin, R. Moret, B. S. Sirima, Natural antibody response to Plasmodium falciparum Exp-1, MSP-3 and GLURP long synthetic peptides and association with protection. Parasite Immunol. 26, 265-272 (2004). (Pubitemid 39576327)
    • (2004) Parasite Immunology , vol.26 , Issue.6-7 , pp. 265-272
    • Meraldi, V.1    Nebie, I.2    Tiono, A.B.3    Diallo, D.4    Sanogo, E.5    Theisen, M.6    Druilhe, P.7    Corradin, G.8    Moret, R.9    Sirima, B.S.10
  • 37
    • 62449310796 scopus 로고    scopus 로고
    • Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness
    • D. I. Stanisic, J. S. Richards, F. J. McCallum, P. Michon, C. L. King, S. Schoepflin, P. R. Gilson, V. J. Murphy, R. F. Anders, I. Mueller, J. G. Beeson, Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness. Infect. Immun. 77, 1165-1174 (2009).
    • (2009) Infect. Immun. , vol.77 , pp. 1165-1174
    • Stanisic, D.I.1    Richards, J.S.2    McCallum, F.J.3    Michon, P.4    King, C.L.5    Schoepflin, S.6    Gilson, P.R.7    Murphy, V.J.8    Anders, R.F.9    Mueller, I.10    Beeson, J.G.11
  • 38
    • 47549116006 scopus 로고    scopus 로고
    • Vaccines: Correlates of vaccine-induced immunity
    • S. A. Plotkin, Vaccines: Correlates of vaccine-induced immunity. Clin. Infect. Dis. 47, 401-409 (2008).
    • (2008) Clin. Infect. Dis. , vol.47 , pp. 401-409
    • Plotkin, S.A.1
  • 39
    • 33644871833 scopus 로고    scopus 로고
    • Immune effector mechanisms in malaria
    • K. Marsh, S. Kinyanjui, Immune effector mechanisms in malaria. Parasite Immunol. 28, 51-60 (2006).
    • (2006) Parasite Immunol. , vol.28 , pp. 51-60
    • Marsh, K.1    Kinyanjui, S.2
  • 42
    • 42149180126 scopus 로고    scopus 로고
    • Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific
    • DOI 10.1128/IAI.01333-07
    • O. J. Akpogheneta, N. O. Duah, K. K. Tetteh, S. Dunyo, D. E. Lanar, M. Pinder, D. J. Conway, Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific. Infect. Immun. 76, 1748-1755 (2008). (Pubitemid 351562020)
    • (2008) Infection and Immunity , vol.76 , Issue.4 , pp. 1748-1755
    • Akpogheneta, O.J.1    Duah, N.O.2    Tetteh, K.K.A.3    Dunyo, S.4    Lanar, D.E.5    Pinder, M.6    Conway, D.J.7
  • 43
    • 34447529116 scopus 로고    scopus 로고
    • IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life
    • S. M. Kinyanjui, D. J. Conway, D. E. Lanar, K. Marsh, IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life. Malar. J. 6, 82 (2007).
    • (2007) Malar. J. , vol.6 , pp. 82
    • Kinyanjui, S.M.1    Conway, D.J.2    Lanar, D.E.3    Marsh, K.4
  • 44
    • 81855175965 scopus 로고    scopus 로고
    • Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria
    • M. B. McCarra, G. Ayodo, P. O. Sumba, J. W. Kazura, A. M. Moormann, D. L. Narum, C. C. John, Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria. Pediatr. Infect. Dis. J. 30, 1037-1042 (2011).
    • (2011) Pediatr. Infect. Dis. J. , vol.30 , pp. 1037-1042
    • McCarra, M.B.1    Ayodo, G.2    Sumba, P.O.3    Kazura, J.W.4    Moormann, A.M.5    Narum, D.L.6    John, C.C.7
  • 46
    • 0037234392 scopus 로고    scopus 로고
    • Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations
    • DOI 10.1038/nm807
    • A. G. Maier, M. T. Duraisingh, J. C. Reeder, S. S. Patel, J. W. Kazura, P. A. Zimmerman, A. F. Cowman, Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations. Nat. Med. 9, 87-92 (2003). (Pubitemid 36098265)
    • (2003) Nature Medicine , vol.9 , Issue.1 , pp. 87-92
    • Maier, A.G.1    Duraisingh, M.T.2    Reeder, J.C.3    Patel, S.S.4    Kazura, J.W.5    Zimmerman, P.A.6    Cowman, A.F.7
  • 47
    • 0028122878 scopus 로고
    • Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum
    • B. K. Sim, C. E. Chitnis, K. Wasniowska, T. J. Hadley, L. H. Miller, Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum. Science 264, 1941-1944 (1994). (Pubitemid 24245642)
    • (1994) Science , vol.264 , Issue.5167 , pp. 1941-1944
    • Sim, B.K.L.1    Chitnis, C.E.2    Wasniowska, K.3    Hadley, T.J.4    Miller, L.H.5
  • 49
    • 84874064187 scopus 로고    scopus 로고
    • PfEMP1 as a target of human immunity and a vaccine candidate against malaria
    • J. G. Beeson, J. A. Chan, F. J. Fowkes, PfEMP1 as a target of human immunity and a vaccine candidate against malaria. Expert Rev. Vaccines 12, 105-108 (2013).
    • (2013) Expert Rev. Vaccines , vol.12 , pp. 105-108
    • Beeson, J.G.1    Chan, J.A.2    Fowkes, F.J.3
  • 52
    • 77957784634 scopus 로고    scopus 로고
    • Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies
    • C. Joos, L. Marrama, H. E. Polson, S. Corre, A. M. Diatta, B. Diouf, J. F. Trape, A. Tall, S. Longacre, R. Perraut, Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies. PLOS One 5, e9871 (2010).
    • (2010) PLOS One , vol.5
    • Joos, C.1    Marrama, L.2    Polson, H.E.3    Corre, S.4    Diatta, A.M.5    Diouf, B.6    Trape, J.F.7    Tall, A.8    Longacre, S.9    Perraut, R.10
  • 53
    • 65549143622 scopus 로고    scopus 로고
    • A conserved multigene family induces cross-reactive antibodies effective in defense against Plasmodium falciparum
    • S. Singh, S. Soe, S. Weisman, J. W. Barnwell, J. L. Pérignon, P. Druilhe, A conserved multigene family induces cross-reactive antibodies effective in defense against Plasmodium falciparum. PLOS One 4, e5410 (2009).
    • (2009) PLOS One , vol.4
    • Singh, S.1    Soe, S.2    Weisman, S.3    Barnwell, J.W.4    Pérignon, J.L.5    Druilhe, P.6
  • 54
    • 18944365782 scopus 로고    scopus 로고
    • Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya
    • DOI 10.1086/430006
    • T. W. Mwangi, A. Ross, R. W. Snow, K. Marsh, Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya. J. Infect. Dis. 191, 1932-1939 (2005). (Pubitemid 40705402)
    • (2005) Journal of Infectious Diseases , vol.191 , Issue.11 , pp. 1932-1939
    • Mwangi, T.W.1    Ross, A.2    Snow, R.W.3    Marsh, K.4
  • 57
    • 84855199947 scopus 로고    scopus 로고
    • R Development Core Team, R:, R Foundation for Statistical Computing, Vienna, Austria
    • R Development Core Team, R: A Language and Environment for Statistical Computing (R Foundation for Statistical Computing, Vienna, Austria, 2011).
    • (2011) A Language and Environment for Statistical Computing
  • 58
    • 1642420994 scopus 로고    scopus 로고
    • A Modified Poisson Regression Approach to Prospective Studies with Binary Data
    • DOI 10.1093/aje/kwh090
    • G. Zou, A modified Poisson regression approach to prospective studies with binary data. Am. J. Epidemiol. 159, 702-706 (2004). (Pubitemid 38405384)
    • (2004) American Journal of Epidemiology , vol.159 , Issue.7 , pp. 702-706
    • Zou, G.1


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