-
1
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson, S.P. and Bartek, J. (2009) The DNA-damage response in human biology and disease. Nature, 461, 1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
2
-
-
78649450619
-
Assembly and function of DNA double-strand break repair foci in mammalian cells
-
Bekker-Jensen, S. and Mailand, N. (2010) Assembly and function of DNA double-strand break repair foci in mammalian cells. DNA Rep., 9, 1219-1228.
-
(2010)
DNA Rep
, vol.9
, pp. 1219-1228
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
3
-
-
80052146061
-
Chromatin and the DNA damage response: The cancer connection
-
Luijsterburg, M.S. and van Attikum, H. (2011) Chromatin and the DNA damage response: the cancer connection. Mol. Oncol., 5, 349-367.
-
(2011)
Mol. Oncol
, vol.5
, pp. 349-367
-
-
Luijsterburg, M.S.1
Van Attikum, H.2
-
4
-
-
75949124023
-
Assembly of checkpoint and repair machineries at DNA damage sites
-
Huen, M.S. and Chen, J. (2010) Assembly of checkpoint and repair machineries at DNA damage sites. Trends Biochem. Sci., 35, 101-108.
-
(2010)
Trends Biochem. Sci
, vol.35
, pp. 101-108
-
-
Huen, M.S.1
Chen, J.2
-
5
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
Polo, S.E. and Jackson, S.P. (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev., 25, 409-433.
-
(2011)
Genes Dev
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
6
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki, M., Clapperton, J.A., Mohammad, D., Yaffe, M.B., Smerdon, S.J. and Jackson, S.P. (2005) MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell, 123, 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
7
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil, C., Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D.H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J. et al. (2009) RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell, 136, 435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
-
8
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart, G.S., Panier, S., Townsend, K., Al-Hakim, A.K., Kolas, N.K., Miller, E.S., Nakada, S., Ylanko, J., Olivarius, S., Mendez, M. et al. (2009) The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell, 136, 420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
-
9
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli, F., Vissers, J.H., van Dijk, W.J., Ikpa, P., Citterio, E., Vermeulen, W., Marteijn, J.A. and Sixma, T.K. (2012) RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell, 150, 1182-1195.
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
Vissers, J.H.2
Van Dijk, W.J.3
Ikpa, P.4
Citterio, E.5
Vermeulen, W.6
Marteijn, J.A.7
Sixma, T.K.8
-
10
-
-
67649404816
-
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
-
Pinato, S., Scandiuzzi, C., Arnaudo, N., Citterio, E., Gaudino, G. and Penengo, L. (2009) RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX. BMC Mol. Biol., 10, 55-69.
-
(2009)
BMC Mol. Biol
, vol.10
, pp. 55-69
-
-
Pinato, S.1
Scandiuzzi, C.2
Arnaudo, N.3
Citterio, E.4
Gaudino, G.5
Penengo, L.6
-
11
-
-
84879888213
-
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
-
Fradet-Turcotte, A., Canny, M.D., Escribano-Diaz, C., Orthwein, A., Leung, C.C., Huang, H., Landry, M.C., Kitevski-LeBlanc, J., Noordermeer, S.M., Sicheri, F. et al. (2013) 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature, 499, 50-54.
-
(2013)
Nature
, vol.499
, pp. 50-54
-
-
Fradet-Turcotte, A.1
Canny, M.D.2
Escribano-Diaz, C.3
Orthwein, A.4
Leung, C.C.5
Huang, H.6
Landry, M.C.7
Kitevski-LeBlanc, J.8
Noordermeer, S.M.9
Sicheri, F.10
-
12
-
-
67349168142
-
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
-
Huang, J., Huen, M.S., Kim, H., Leung, C.C., Glover, J.N., Yu, X. and Chen, J. (2009) RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat. Cell Biol., 11, 592-603.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 592-603
-
-
Huang, J.1
Huen, M.S.2
Kim, H.3
Leung, C.C.4
Glover, J.N.5
Yu, X.6
Chen, J.7
-
13
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen, M.S., Grant, R., Manke, I., Minn, K., Yu, X., Yaffe, M.B. and Chen, J. (2007) RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell, 131, 901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
14
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas, N.K., Chapman, J.R., Nakada, S., Ylanko, J., Chahwan, R., Sweeney, F.D., Panier, S., Mendez, M., Wildenhain, J., Thomson, T.M. et al. (2007) Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science, 318, 1637-1640.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
-
15
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand, N., Bekker-Jensen, S., Faustrup, H., Melander, F., Bartek, J., Lukas, C. and Lukas, J. (2007) RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell, 131, 887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
16
-
-
36749025467
-
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
Wang, B. and Elledge, S.J. (2007) Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc. Natl. Acad. Sci. U.S.A., 104, 20759-20763.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
Elledge, S.J.2
-
17
-
-
77956379478
-
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage
-
Larsen, D.H., Poinsignon, C., Gudjonsson, T., Dinant, C., Payne, M.R., Hari, F.J., Rendtlew Danielsen, J.M., Menard, P., Sand, J.C., Stucki, M. et al. (2010) The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. J. Cell Biol., 190, 731-740.
-
(2010)
J. Cell Biol
, vol.190
, pp. 731-740
-
-
Larsen, D.H.1
Poinsignon, C.2
Gudjonsson, T.3
Dinant, C.4
Payne, M.R.5
Hari, F.J.6
Rendtlew Danielsen, J.M.7
Menard, P.8
Sand, J.C.9
Stucki, M.10
-
18
-
-
84861895067
-
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
-
Luijsterburg, M.S., Acs, K., Ackermann, L., Wiegant, W.W., Bekker-Jensen, S., Larsen, D.H., Khanna, K.K., van Attikum, H., Mailand, N. and Dantuma, N.P. (2012) A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO J., 31, 2511-2527.
-
(2012)
EMBO J
, vol.31
, pp. 2511-2527
-
-
Luijsterburg, M.S.1
Acs, K.2
Ackermann, L.3
Wiegant, W.W.4
Bekker-Jensen, S.5
Larsen, D.H.6
Khanna, K.K.7
Van Attikum, H.8
Mailand, N.9
Dantuma, N.P.10
-
19
-
-
84876328368
-
Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling
-
Smeenk, G., Wiegant, W.W., Marteijn, J.A., Luijsterburg, M.S., Sroczynski, N., Costelloe, T., Romeijn, R.J., Pastink, A., Mailand, N., Vermeulen, W. et al. (2013) Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling. J. Cell Sci., 126, 889-903.
-
(2013)
J. Cell Sci
, vol.126
, pp. 889-903
-
-
Smeenk, G.1
Wiegant, W.W.2
Marteijn, J.A.3
Luijsterburg, M.S.4
Sroczynski, N.5
Costelloe, T.6
Romeijn, R.J.7
Pastink, A.8
Mailand, N.9
Vermeulen, W.10
-
20
-
-
84865232294
-
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
-
Gudjonsson, T., Altmeyer, M., Savic, V., Toledo, L., Dinant, C., Grofte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, S. et al. (2012) TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell, 150, 697-709.
-
(2012)
Cell
, vol.150
, pp. 697-709
-
-
Gudjonsson, T.1
Altmeyer, M.2
Savic, V.3
Toledo, L.4
Dinant, C.5
Grofte, M.6
Bartkova, J.7
Poulsen, M.8
Oka, Y.9
Bekker-Jensen, S.10
-
21
-
-
84878758649
-
The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
-
Mosbech, A., Lukas, C., Bekker-Jensen, S. and Mailand, N. (2013) The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases. J. Biol. Chem., 288, 16579-16587.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 16579-16587
-
-
Mosbech, A.1
Lukas, C.2
Bekker-Jensen, S.3
Mailand, N.4
-
22
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada, S., Tai, I., Panier, S., Al-Hakim, A., Iemura, S., Juang, Y.C., O'Donnell, L., Kumakubo, A., Munro, M., Sicheri, F. et al. (2010) Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature, 466, 941-946.
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
O'Donnell, L.7
Kumakubo, A.8
Munro, M.9
Sicheri, F.10
-
23
-
-
62549140202
-
The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks
-
Shao, G., Lilli, D.R., Patterson-Fortin, J., Coleman, K.A., Morrissey, D.E. and Greenberg, R.A. (2009) The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks. Proc. Natl. Acad. Sci. U.S.A., 106, 3166-3171.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 3166-3171
-
-
Shao, G.1
Lilli, D.R.2
Patterson-Fortin, J.3
Coleman, K.A.4
Morrissey, D.E.5
Greenberg, R.A.6
-
24
-
-
84922010371
-
Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
-
Nishi, R., Wijnhoven, P., le Sage, C., Tjeertes, J., Galanty, Y., Forment, J.V., Clague, M.J., Urbe, S. and Jackson, S.P. (2014) Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity. Nat. Cell Biol., 16, 1016-1026.
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 1016-1026
-
-
Nishi, R.1
Wijnhoven, P.2
Le Sage, C.3
Tjeertes, J.4
Galanty, Y.5
Forment, J.V.6
Clague, M.J.7
Urbe, S.8
Jackson, S.P.9
-
25
-
-
84894067659
-
Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice
-
Kato, K., Nakajima, K., Ui, A., Muto-Terao, Y., Ogiwara, H. and Nakada, S. (2014) Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice. Mol. Cell, 53, 617-630.
-
(2014)
Mol. Cell
, vol.53
, pp. 617-630
-
-
Kato, K.1
Nakajima, K.2
Ui, A.3
Muto-Terao, Y.4
Ogiwara, H.5
Nakada, S.6
-
26
-
-
84892562030
-
USP3 counteracts RNF168 via deubiquitinating H2A and gammaH2AX at lysine 13 and 15
-
Sharma, N., Zhu, Q., Wani, G., He, J., Wang, Q.E. and Wani, A.A. (2013) USP3 counteracts RNF168 via deubiquitinating H2A and gammaH2AX at lysine 13 and 15. Cell Cycle, 13, 106-114.
-
(2013)
Cell Cycle
, vol.13
, pp. 106-114
-
-
Sharma, N.1
Zhu, Q.2
Wani, G.3
He, J.4
Wang, Q.E.5
Wani, A.A.6
-
27
-
-
84862777619
-
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
-
Feng, L. and Chen, J. (2012) The E3 ligase RNF8 regulates KU80 removal and NHEJ repair. Nat. Struct. Mol. Biol., 19, 201-206.
-
(2012)
Nat. Struct. Mol. Biol
, vol.19
, pp. 201-206
-
-
Feng, L.1
Chen, J.2
-
28
-
-
33646196532
-
Regulation of DNA repair by ubiquitylation
-
Huang, T.T. and D'Andrea, A.D. (2006) Regulation of DNA repair by ubiquitylation. Nat. Rev. Mol. Cell Biol., 7, 323-334.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 323-334
-
-
Huang, T.T.1
D'Andrea, A.D.2
-
29
-
-
75949122330
-
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
-
Noon, A.T., Shibata, A., Rief, N., Lobrich, M., Stewart, G.S., Jeggo, P.A. and Goodarzi, A.A. (2010) 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol., 12, 177-184.
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 177-184
-
-
Noon, A.T.1
Shibata, A.2
Rief, N.3
Lobrich, M.4
Stewart, G.S.5
Jeggo, P.A.6
Goodarzi, A.A.7
-
30
-
-
84871566041
-
MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination
-
Zhang, F., Bick, G., Park, J.Y. and Andreassen, P.R. (2012) MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination. J. Cell Sci., 125, 6049-6057.
-
(2012)
J. Cell Sci
, vol.125
, pp. 6049-6057
-
-
Zhang, F.1
Bick, G.2
Park, J.Y.3
Andreassen, P.R.4
-
31
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNA-damage response
-
Zhang, F., Ma, J., Wu, J., Ye, L., Cai, H., Xia, B. and Yu, X. (2009) PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr. Biol., 19, 524-529.
-
(2009)
Curr. Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
Ma, J.2
Wu, J.3
Ye, L.4
Cai, H.5
Xia, B.6
Yu, X.7
-
32
-
-
67651166786
-
PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2
-
Zhang, F., Fan, Q., Ren, K. and Andreassen, P.R. (2009) PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. Mol. Cancer Res., 7, 1110-1118.
-
(2009)
Mol. Cancer Res
, vol.7
, pp. 1110-1118
-
-
Zhang, F.1
Fan, Q.2
Ren, K.3
Andreassen, P.R.4
-
33
-
-
66349096607
-
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
-
Sy, S.M., Huen, M.S. and Chen, J. (2009) PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc. Natl. Acad. Sci. U.S.A., 106, 7155-7160.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 7155-7160
-
-
Sy, S.M.1
Huen, M.S.2
Chen, J.3
-
34
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen, M.S., Sy, S.M. and Chen, J. (2010) BRCA1 and its toolbox for the maintenance of genome integrity. Nat. Rev. Mol. Cell Biol., 11, 138-148.
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
35
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim, H., Chen, J. and Yu, X. (2007) Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science, 316, 1202-1205.
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
36
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian, B., Shao, G., Lilli, D.R., Culhane, A.C., Moreau, L.A., Xia, B., Livingston, D.M. and Greenberg, R.A. (2007) RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science, 316, 1198-1202.
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
Culhane, A.C.4
Moreau, L.A.5
Xia, B.6
Livingston, D.M.7
Greenberg, R.A.8
-
37
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang, B., Matsuoka, S., Ballif, B.A., Zhang, D., Smogorzewska, A., Gygi, S.P. and Elledge, S.J. (2007) Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science, 316, 1194-1198.
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
38
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu, Y., Scully, R., Sobhian, B., Xie, A., Shestakova, E. and Livingston, D.M. (2011) RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev., 25, 685-700.
-
(2011)
Genes Dev
, vol.25
, pp. 685-700
-
-
Hu, Y.1
Scully, R.2
Sobhian, B.3
Xie, A.4
Shestakova, E.5
Livingston, D.M.6
-
39
-
-
84890324730
-
Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
-
Kakarougkas, A., Ismail, A., Katsuki, Y., Freire, R., Shibata, A. and Jeggo, P.A. (2013) Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection. Nucleic Acids Res., 41, 10298-10311.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 10298-10311
-
-
Kakarougkas, A.1
Ismail, A.2
Katsuki, Y.3
Freire, R.4
Shibata, A.5
Jeggo, P.A.6
-
40
-
-
79953869356
-
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
-
Coleman, K.A. and Greenberg, R.A. (2011) The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J. Biol. Chem., 286, 13669-13680.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 13669-13680
-
-
Coleman, K.A.1
Greenberg, R.A.2
-
41
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag, N.M., Rafalska-Metcalf, I.U., Balane-Bolivar, C., Janicki, S.M. and Greenberg, R.A. (2010) ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell, 141, 970-981.
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
42
-
-
84875224166
-
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
-
Tang, J., Cho, N.W., Cui, G., Manion, E.M., Shanbhag, N.M., Botuyan, M.V., Mer, G. and Greenberg, R.A. (2013) Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat. Struct. Mol. Biol., 20, 317-325.
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 317-325
-
-
Tang, J.1
Cho, N.W.2
Cui, G.3
Manion, E.M.4
Shanbhag, N.M.5
Botuyan, M.V.6
Mer, G.7
Greenberg, R.A.8
-
43
-
-
38849199681
-
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
-
Sakaue-Sawano, A., Kurokawa, H., Morimura, T., Hanyu, A., Hama, H., Osawa, H., Kashiwagi, S., Fukami, K., Miyata, T., Miyoshi, H. et al. (2008) Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell, 132, 487-498.
-
(2008)
Cell
, vol.132
, pp. 487-498
-
-
Sakaue-Sawano, A.1
Kurokawa, H.2
Morimura, T.3
Hanyu, A.4
Hama, H.5
Osawa, H.6
Kashiwagi, S.7
Fukami, K.8
Miyata, T.9
Miyoshi, H.10
-
44
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa, M.E., Bennett, E.J., Gygi, S.P. and Harper, J.W. (2009) Defining the human deubiquitinating enzyme interaction landscape. Cell, 138, 389-403.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
45
-
-
82955233157
-
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
-
Acs, K., Luijsterburg, M.S., Ackermann, L., Salomons, F.A., Hoppe, T. and Dantuma, N.P. (2011) The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat. Struct. Mol. Biol., 18, 1345-1350.
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 1345-1350
-
-
Acs, K.1
Luijsterburg, M.S.2
Ackermann, L.3
Salomons, F.A.4
Hoppe, T.5
Dantuma, N.P.6
-
46
-
-
84884897397
-
Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining
-
Helfricht, A., Wiegant, W.W., Thijssen, P.E., Vertegaal, A.C., Luijsterburg, M.S. and van Attikum, H. (2013) Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining. Cell Cycle, 12, 3070-3082.
-
(2013)
Cell Cycle
, vol.12
, pp. 3070-3082
-
-
Helfricht, A.1
Wiegant, W.W.2
Thijssen, P.E.3
Vertegaal, A.C.4
Luijsterburg, M.S.5
Van Attikum, H.6
-
47
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce, A.J., Johnson, R.D., Thompson, L.H. and Jasin, M. (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13, 2633-2638.
-
(1999)
Genes Dev
, vol.13
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
Jasin, M.4
-
48
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo, N., Cheng, A., Huang, N. and Stark, J.M. (2008) Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet., 4, e1000110.
-
(2008)
PLoS Genet
, vol.4
, pp. e1000110
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
49
-
-
79958030960
-
The USP1/UAF1 complex promotes double-strand break repair through homologous recombination
-
Murai, J., Yang, K., Dejsuphong, D., Hirota, K., Takeda, S. and D'Andrea, A.D. (2011) The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Mol. Cell. Biol., 31, 2462-2469.
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 2462-2469
-
-
Murai, J.1
Yang, K.2
Dejsuphong, D.3
Hirota, K.4
Takeda, S.5
D'Andrea, A.D.6
-
50
-
-
84891912266
-
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
-
Yu, H., Pak, H., Hammond-Martel, I., Ghram, M., Rodrigue, A., Daou, S., Barbour, H., Corbeil, L., Hebert, J., Drobetsky, E. et al. (2013) Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc. Natl. Acad. Sci. U.S.A., 111, 285-290.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 285-290
-
-
Yu, H.1
Pak, H.2
Hammond-Martel, I.3
Ghram, M.4
Rodrigue, A.5
Daou, S.6
Barbour, H.7
Corbeil, L.8
Hebert, J.9
Drobetsky, E.10
-
51
-
-
84864919890
-
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks
-
Panier, S., Ichijima, Y., Fradet-Turcotte, A., Leung, C.C., Kaustov, L., Arrowsmith, C.H. and Durocher, D. (2012) Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol. Cell, 47, 383-395.
-
(2012)
Mol. Cell
, vol.47
, pp. 383-395
-
-
Panier, S.1
Ichijima, Y.2
Fradet-Turcotte, A.3
Leung, C.C.4
Kaustov, L.5
Arrowsmith, C.H.6
Durocher, D.7
-
52
-
-
84863793933
-
A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
-
Gatti, M., Pinato, S., Maspero, E., Soffientini, P., Polo, S. and Penengo, L. (2012) A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase. Cell Cycle, 11, 2538-2544.
-
(2012)
Cell Cycle
, vol.11
, pp. 2538-2544
-
-
Gatti, M.1
Pinato, S.2
Maspero, E.3
Soffientini, P.4
Polo, S.5
Penengo, L.6
-
53
-
-
33748065304
-
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
-
McCabe, N., Turner, N.C., Lord, C.J., Kluzek, K., Bialkowska, A., Swift, S., Giavara, S., O'Connor, M.J., Tutt, A.N., Zdzienicka, M.Z. et al. (2006) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res., 66, 8109-8115.
-
(2006)
Cancer Res
, vol.66
, pp. 8109-8115
-
-
McCabe, N.1
Turner, N.C.2
Lord, C.J.3
Kluzek, K.4
Bialkowska, A.5
Swift, S.6
Giavara, S.7
O'Connor, M.J.8
Tutt, A.N.9
Zdzienicka, M.Z.10
-
54
-
-
63049083118
-
MERIT40 facilitates BRCA1 localization and DNA damage repair
-
Feng, L., Huang, J. and Chen, J. (2009) MERIT40 facilitates BRCA1 localization and DNA damage repair. Genes Dev., 23, 719-728.
-
(2009)
Genes Dev
, vol.23
, pp. 719-728
-
-
Feng, L.1
Huang, J.2
Chen, J.3
-
55
-
-
84871559319
-
The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination
-
Lu, C.S., Truong, L.N., Aslanian, A., Shi, L.Z., Li, Y., Hwang, P.Y., Koh, K.H., Hunter, T., Yates, J.R. 3rd, Berns, M.W. et al. (2012) The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. J. Biol. Chem., 287, 43984-43994.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 43984-43994
-
-
Lu, C.S.1
Truong, L.N.2
Aslanian, A.3
Shi, L.Z.4
Li, Y.5
Hwang, P.Y.6
Koh, K.H.7
Hunter, T.8
Yates, R.J.9
Berns, M.W.10
-
56
-
-
84867115508
-
RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1
-
Nakada, S., Yonamine, R.M. and Matsuo, K. (2012) RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1. Cancer Res., 72, 4974-4983.
-
(2012)
Cancer Res
, vol.72
, pp. 4974-4983
-
-
Nakada, S.1
Yonamine, R.M.2
Matsuo, K.3
-
57
-
-
79959326643
-
Critical roles of ring finger protein RNF8 in replication stress responses
-
Sy, S.M., Jiang, J., Dong, S.S., Lok, G.T., Wu, J., Cai, H., Yeung, E.S., Huang, J., Chen, J., Deng, Y. et al. (2011) Critical roles of ring finger protein RNF8 in replication stress responses. J. Biol. Chem., 286, 22355-22361.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 22355-22361
-
-
Sy, S.M.1
Jiang, J.2
Dong, S.S.3
Lok, G.T.4
Wu, J.5
Cai, H.6
Yeung, E.S.7
Huang, J.8
Chen, J.9
Deng, Y.10
-
58
-
-
80455145246
-
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
-
Meerang, M., Ritz, D., Paliwal, S., Garajova, Z., Bosshard, M., Mailand, N., Janscak, P., Hubscher, U., Meyer, H. and Ramadan, K. (2011) The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat. Cell Biol., 13, 1376-1382.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1376-1382
-
-
Meerang, M.1
Ritz, D.2
Paliwal, S.3
Garajova, Z.4
Bosshard, M.5
Mailand, N.6
Janscak, P.7
Hubscher, U.8
Meyer, H.9
Ramadan, K.10
-
59
-
-
84869996067
-
RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1
-
Munoz, M.C., Laulier, C., Gunn, A., Cheng, A., Robbiani, D.F., Nussenzweig, A. and Stark, J.M. (2012) RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1. J. Biol. Chem., 287, 40618-40628.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 40618-40628
-
-
Munoz, M.C.1
Laulier, C.2
Gunn, A.3
Cheng, A.4
Robbiani, D.F.5
Nussenzweig, A.6
Stark, J.M.7
-
60
-
-
84876877091
-
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
-
Escribano-Diaz, C., Orthwein, A., Fradet-Turcotte, A., Xing, M., Young, J.T., Tkac, J., Cook, M.A., Rosebrock, A.P., Munro, M., Canny, M.D. et al. (2013) A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol. Cell, 49, 872-883.
-
(2013)
Mol. Cell
, vol.49
, pp. 872-883
-
-
Escribano-Diaz, C.1
Orthwein, A.2
Fradet-Turcotte, A.3
Xing, M.4
Young, J.T.5
Tkac, J.6
Cook, M.A.7
Rosebrock, A.P.8
Munro, M.9
Canny, M.D.10
-
61
-
-
84891353801
-
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
-
Bohgaki, M., Bohgaki, T., El Ghamrasni, S., Srikumar, T., Maire, G., Panier, S., Fradet-Turcotte, A., Stewart, G.S., Raught, B., Hakem, A. et al. (2013) RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks. Proc. Natl. Acad. Sci. U.S.A., 110, 20982-20987.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 20982-20987
-
-
Bohgaki, M.1
Bohgaki, T.2
El Ghamrasni, S.3
Srikumar, T.4
Maire, G.5
Panier, S.6
Fradet-Turcotte, A.7
Stewart, G.S.8
Raught, B.9
Hakem, A.10
-
62
-
-
84905995383
-
Germline mutations in BAP1 impair its function in DNA double-strand break repair
-
Ismail, I.H., Davidson, R., Gagne, J.P., Xu, Z.Z., Poirier, G.G. and Hendzel, M.J. (2014) Germline mutations in BAP1 impair its function in DNA double-strand break repair. Cancer Res., 74, 4282-4294.
-
(2014)
Cancer Res
, vol.74
, pp. 4282-4294
-
-
Ismail, I.H.1
Davidson, R.2
Gagne, J.P.3
Xu, Z.Z.4
Poirier, G.G.5
Hendzel, M.J.6
-
63
-
-
36049036216
-
Human USP3 is a chromatin modifier required for S phase progression and genome stability
-
Nicassio, F., Corrado, N., Vissers, J.H., Areces, L.B., Bergink, S., Marteijn, J.A., Geverts, B., Houtsmuller, A.B., Vermeulen, W., Di Fiore, P.P. et al. (2007) Human USP3 is a chromatin modifier required for S phase progression and genome stability. Curr. Biol., 17, 1972-1977.
-
(2007)
Curr. Biol
, vol.17
, pp. 1972-1977
-
-
Nicassio, F.1
Corrado, N.2
Vissers, J.H.3
Areces, L.B.4
Bergink, S.5
Marteijn, J.A.6
Geverts, B.7
Houtsmuller, A.B.8
Vermeulen, W.9
Di Fiore, P.P.10
-
64
-
-
84901599553
-
A draft map of the human proteome
-
Kim, M.S., Pinto, S.M., Getnet, D., Nirujogi, R.S., Manda, S.S., Chaerkady, R., Madugundu, A.K., Kelkar, D.S., Isserlin, R., Jain, S. et al. (2014) A draft map of the human proteome. Nature, 509, 575-581.
-
(2014)
Nature
, vol.509
, pp. 575-581
-
-
Kim, M.S.1
Pinto, S.M.2
Getnet, D.3
Nirujogi, R.S.4
Manda, S.S.5
Chaerkady, R.6
Madugundu, A.K.7
Kelkar, D.S.8
Isserlin, R.9
Jain, S.10
-
65
-
-
84901611036
-
Mass-spectrometry-based draft of the human proteome
-
Wilhelm, M., Schlegl, J., Hahne, H., Moghaddas Gholami, A., Lieberenz, M., Savitski, M.M., Ziegler, E., Butzmann, L., Gessulat, S., Marx, H. et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature, 509, 582-587.
-
(2014)
Nature
, vol.509
, pp. 582-587
-
-
Wilhelm, M.1
Schlegl, J.2
Hahne, H.3
Moghaddas Gholami, A.4
Lieberenz, M.5
Savitski, M.M.6
Ziegler, E.7
Butzmann, L.8
Gessulat, S.9
Marx, H.10
|