Phlebotomy, a bridge between laboratory and patient

Biochemia Medica

Volumn 26, Issue 1, 2016, Pages 17-33

  Ialongo, Cristiano ^a   Bernardini, Sergio ^a,b  

^a TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Evidence based medicine; Laboratory testing; Patient safety; Phlebotomy; Preanalytical phase; Preanalytical variability; Venipuncture

Indexed keywords

ANATOMY; CLINICAL LABORATORY; GREECE; HUMAN; MEDICAL PRACTICE; MEDICINE; PATIENT SAFETY; PERIPHERAL VEIN; PHLEBOTOMIST; PHLEBOTOMY; VEIN PUNCTURE; ANATOMY AND HISTOLOGY; DEVICES; DIAGNOSTIC ERROR; FOREARM; HEMATOLOGY; LABORATORY; PREVENTION AND CONTROL; PROCEDURES; QUALITY CONTROL; STANDARDS; VASCULARIZATION; VEIN;

DIAGNOSTIC ERRORS; FOREARM; HEMATOLOGY; HUMANS; LABORATORIES; PATIENT SAFETY; PHLEBOTOMY; QUALITY CONTROL; VEINS;

EID: 84957885302     PISSN: 13300962     EISSN: None     Source Type: Journal    
DOI: 10.11613/BM.2016.002     Document Type: Review

References (132)

1. Parapia LA. History of bloodletting by phlebotomy. Br J Haematol 2008;143:490-5. http://dx.doi.org/10.1111/j.1365-2141.2008.07361.x.
2. Forsman RW. Why is the laboratory an afterthought for managed care organizations? Clin Chem 1996;42:813-6.
3. Kravetz RE. Hypodermic syringe. Am J Gastroenterol 2005;10:2614. http://dx.doi.org/10.1111/j.1572-0241.2005.00397.x.
4. Ernst DJ, Ernst C. Phlebotomy tools of the trade. Home healthc nurse 2002;20:151-3. http://dx.doi.org/10.1097/00004045-200203000-00005.
5. Fujii C. Clarification of the characteristics of needle-tip movement during vacuum venipuncture to improve safety. Vasc Health Risk Manag 2013;9:381-90. http://dx.doi.org/10.2147/VHRM.S47490.
6. Lippi G, Salvagno GL, Brocco G, Guidi GC. Preanalytical variability in laboratory testing:influence of the blood drawing technique. Clin Chem Lab Med 2005;43:319-25. http://dx.doi.org/10.1515/CCLM.2005.055.
7. Fujii C. Vacuum-venipuncture skills:time required and importance of tube order. Vasc Health Risk Manag 2013;9:457-64. http://dx.doi.org/10.2147/VHRM.S49702.
8. Gershon RR, Pearson JM, Sherman MF, Samar SM, Canton AN, Stone PW. The prevalence and risk factors for percutaneous injuries in registered nurses in the home health care sector. Am J Infect Control 2009;37:525-33. http://dx.doi.org/10.1016/j.ajic.2008.10.022.
9. European Council Directive 2010/32/EU. Available at: http://europeanbiosafetynetwork.eu/OJEU.pdf. Accessed: September 15, 2015
10. Bush V, Cohen R. The Evolution of Evacuated Blood Collection Tubes. Lab Medicine 2003;34:304-10. http://dx.doi.org/10.1309/JCQE33NBYGE0FFQR.
11. Simundic AM, Cornes MP, Grankvist K, Lippi G, Nybo M, Ceriotti F, et al. Colour coding for blood collection tube closures-a call for harmonisation. Clin Chem Lab Med 2015;53:371-6. http://dx.doi.org/10.1515/cclm-2014-0927.
12. McGuff J, Popovsky MA. Needlestick injuries in blood collection staff. A retrospective analysis. Transfusion 1989;29:693-5. http://dx.doi.org/10.1046/j.1537-2995.1989.29890020442.x.
13. Holton J, Prince M. Blood contamination during venepuncture and laboratory manipulations of specimen tubes. J Hosp Infect 1986;8:178-83. http://dx.doi.org/10.1016/0195-6701(86)90044-7.
14. On track for success for more than 50 years. Available at: https://www.sarstedt.com/en/the-company/about-us/history/Accessed: September 15, 2015
15. Lippi G, Bonelli P, Bonfanti L, Cervellin G. The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department. Biochem Med (Zagreb) 2015;25:69-72. http://dx.doi.org/10.11613/BM.2015.008.
16. Lippi G, Avanzini P, Musa R, Sandei F, Aloe R, Cervellin G. Evaluation of sample hemolysis in blood collected by SMonovette using vacuum or aspiration mode. Biochem Med (Zagreb) 2013;23:64-9. http://dx.doi.org/10.11613/BM.2013.008.
17. Goldman M, Roy G, Frechette N, Decary F, Massicotte L, Delage G. Evaluation of donor skin disinfection methods. Transfusion 1997;37:309-12. http://dx.doi.org/10.1046/j.1537-2995.1997.37397240214.x.
18. Ramirez-Arcos S, Goldman M. Skin disinfection methods:prospective evaluation and postimplementation results. Transfusion 2010;50:59-64. http://dx.doi.org/10.1111/j.1537-2995.2009.02434.x.
19. Evans CA, Mattern KL. The bacterial flora of the antecubital fossa:the efficacy of alcohol disinfection of this site, the palm and the forehead. J Invest Dermatol 1980;75:140-3. http://dx.doi.org/10.1111/1523-1747.ep12521658.
20. Muller FO, Hundt HK. Ethyl alcohol: contamination of blood specimens. S Afr Med J 1976;50:91.
21. Yigit O, Arslan S. Swabbing skin with alcohol could change the blood alcohol level significantly. J Emerg Med 2012;43:718-9. http://dx.doi.org/10.1016/j.jemermed.2011.07.025.
22. Caldeira D, David C, Sampaio C. Skin antiseptics in venous puncture-site disinfection for prevention of blood culture contamination:systematic review with meta-analysis. J Hosp Infect 2011;77:223-32. http://dx.doi.org/10.1016/j.jhin.2010.10.015.
23. McIvor RA, Cosbey SH. Effect of using alcoholic and nonalcoholic skin cleansing swabs when sampling blood for alcohol estimation using gas chromatography. Br J Clin Pract 1990;44:235-6.
24. Tucker A, Trethewy C. Lack of effect on blood alcohol level of swabbing venepuncture sites with 70% isopropyl alcohol. Emerg Med Australas 2010;22:9-12. http://dx.doi.org/10.1111/j.1742-6723.2009.01248.x.
25. Malingre M, Ververs T, Bos S, van Kesteren C, van Rijn H. Alcohol swabs and venipuncture in a routine hospital setting:no effect on blood ethanol measurement. Ther Drug Monit 2005;27:403-4. http://dx.doi.org/10.1097/01.ftd.0000158868.74618.dd.
26. Pendlington RU, Whittle E, Robinson JA, Howes D. Fate of ethanol topically applied to skin. Food Chem Toxicol 2001;39:169-74. http://dx.doi.org/10.1016/S0278-6915(00)00120-4.
27. Brown CG. Comment on “Blood Alcohol Concentration Using Non-Alcohol- and Alcohol-Containing Skin Antiseptics”. Ann Emerg Med 1983;12:593-5. http://dx.doi.org/10.1016/S0196-0644(83)80326-6.
28. Maiwald M, Chan ES. The forgotten role of alcohol:a systematic review and meta-analysis of the clinical efficacy and perceived role of chlorhexidine in skin antisepsis. PLoS One 2012; 7:e44277. http://dx.doi.org/10.1371/journal.pone.0044277.
29. Calfee DP, Farr BM. Comparison of four antiseptic preparations for skin in the prevention of contamination of percutaneously drawn blood cultures:a randomized trial. J Clin Microbiol 2002;40:1660-5. http://dx.doi.org/10.1128/JCM.40.5.1660-1665.2002.
30. Kiyoyama T, Tokuda Y, Shiiki S, Hachiman T, Shimasaki T, Endo K. Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination. J Clin Microbiol 2009;47:54-8. http://dx.doi.org/10.1128/JCM.01425-08.
31. Qamruddin A, Khanna N, Orr D. Peripheral blood culture contamination in adults and venepuncture technique:prospective cohort study. J Clin Pathol 2008;61: 509-13. http://dx.doi.org/10.1136/jcp.2007.047647.
32. Kerstein RL, Fellowes C. Novel fit for purpose single use tourniquet:best of both worlds. J Med Eng Technol 2009;33:475-80. http://dx.doi.org/10.1080/03091900902952667.
33. Leitch A, McCormick I, Gunn I, Gillespie T. Reducing the potential for phlebotomy tourniquets to act as a reservoir for meticillin-resistant Staphylococcus aureus. J Hosp Infect 2006;63:428-31. http://dx.doi.org/10.1016/j.jhin.2006.03.006.
34. Gill HS, Prausnitz MR. Does needle size matter? J Diabetes Sci Technol 2007;1:725-9. http://dx.doi.org/10.1177/193229680700100517.
35. Arendt-Nielsen L, Egekvist H, Bjerring P. Pain following controlled cutaneous insertion of needles with different diameters. Somatosens Mot Res 2006;23:37-43. http://dx.doi.org/10.1080/08990220600700925.
36. Egekvist H, Bjerring P, Arendt-Nielsen L. Pain and mechanical injury of human skin following needle insertions. Eur J Pain 1999;3:41-9. http://dx.doi.org/10.1016/S1090-3801(99)90187-8.
37. Egekvist H, Bjerring P, Arendt Nielsen T. Regional variations in pain to controlled mechanical skin traumas from automatic needle insertions and relations to ultrasonography. Skin Res Technol 1999;5:247-54. http://dx.doi.org/10.1111/j.1600-0846.1999.tb00137.x.
38. Newman B, Siegfried B, Buchanan L. Are vasovagal reaction rates in blood donors related to the duration of the phlebotomy? Transfusion 2008;48:568-9. http://dx.doi.org/10.1111/j.1537-2995.2007.01638.x.
39. Newman BH. Management of young blood donors. Transfus Med Hemother 2014;41:284-95. http://dx.doi.org/10.1159/000364849.
40. Zempsky WT, Schmitz ML, Meyer JM. Safety and efficacy of needle-free powder lidocaine delivery system in adult patients undergoing venipuncture or peripheral venous cannulation:randomized, double-blind, placebo-controlled trial. Clin J Pain 2015; [Epub ahead of print]. http://dx.doi.org/10.1097/AJP.0000000000000257.
41. Zempsky WT, Bean-Lijewski J, Kauffman RE, Koh JL, Malviya SV, Rose JB, et al. Needle-free powder lidocaine delivery system provides rapid effective analgesia for venipuncture or cannulation pain in children:randomized, double-blind comparison of venipuncture and venous cannulation pain after fast-onset needle-free powder lidocaine or placebo treatment trial. Pediatrics 2008;121:979-87. http://dx.doi.org/10.1542/peds.2007-0814.
42. Patterson P, Hussa AA, Fedele KA, Vegh GL, Hackman CM. Comparison of 4 analgesic agents for venipuncture. AANA J 2000;68:43-51.
43. Brenner SM, Rupp V, Boucher J, Weaver K, Dusza SW, Bokovoy J. A randomized, controlled trial to evaluate topical anesthetic for 15 minutes before venipuncture in pediatrics. Am J Emerg Med 2013;31:20-5. http://dx.doi.org/10.1016/j.ajem.2012.05.003.
44. Schmitz ML, Zempsky WT, Meyer JM. Safety and efficacy of a needle-free powder lidocaine delivery system in pediatric patients undergoing venipuncture or peripheral venous cannulation:randomized bouble-blind COMFORT-004 trial. Clin Ther 2015;37:1761-72. http://dx.doi.org/10.1016/j.clinthera.2015.05.515.
45. Migdal M, Chudzynska-Pomianowska E, Vause E, Henry E, Lazar J. Rapid, needle-free delivery of lidocaine for reducing the pain of venipuncture among pediatric subjects. Pediatrics 2005;115:e393-8. http://dx.doi.org/10.1542/peds.2004-0656.
46. Patakfalvi L, Benohanian A. Needle-free anaesthesia, a promising option for the needle-phobic patient. Br J Dermatol 2014;170:1191-2. http://dx.doi.org/10.1111/bjd.12784.
47. Hogan ME, Smart S, Shah V, Taddio A. A systematic review of vapocoolants for reducing pain from venipuncture and venous cannulation in children and adults. J Emerg Med 2014;47:736-49. http://dx.doi.org/10.1016/j.jemermed.2014.06.028.
48. Braz J, Solorzano C, Wang X, Basbaum AI. Transmitting pain and itch messages:a contemporary view of the spinal cord circuits that generate gate control. Neuron 2014;82:522-36. http://dx.doi.org/10.1016/j.neuron.2014.01.018.
49. Mendell LM. Constructing and deconstructing the gate theory of pain. Pain 2014;155:210-6. http://dx.doi.org/10.1016/j.pain.2013.12.010.
50. Baxter AL, Leong T, Mathew B. External thermomechanical stimulation versus vapocoolant for adult venipuncture pain: pilot data on a novel device. Clin J Pain 2009;25:705-10. http://dx.doi.org/10.1097/AJP.0b013e3181af1236.
51. Baxter AL, Cohen LL, McElvery HL, Lawson ML, von Baeyer CL. An integration of vibration and cold relieves venipuncture pain in a pediatric emergency department. Pediatr Emerg Care 2011;27:1151-6. http://dx.doi.org/10.1097/PEC.0b013e318237ace4.
52. Schreiber S, Cozzi G, Rutigliano R, Assandro P, Tubaro M, Cortellazzo Wiel L, et al. Analgesia by cooling vibration during venipuncture in children with cognitive impairment. Acta Paediatr 2016;105:e12-6. http://dx.doi.org/10.1111/apa.13224.
53. Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Quality impact on diagnostic blood specimen collection using a new device to relieve venipuncture pain. Indian J Clin Biochem 2013;28:235-41. http://dx.doi.org/10.1007/s12291-013-0319-y.
54. Lima-Oliveira G, Lippi G, Salvagno GL, Campelo MD, Tajra KS, dos Santos Gomes F, et al. A new device to relieve venipuncture pain can affect haematology test results. Blood transfus 2014;12:S6-S10.
55. Baxter AL, Lawson ML. Concerns with the methodology, analysis and discussion of the Buzzy(R) and transillumination comparison article. Blood transfus 2014;12:S3-S5.
56. Deacon B, Abramowitz J. Fear of needles and vasovagal reactions among phlebotomy patients. J Anxiety Disord 2006;20:946-60. http://dx.doi.org/10.1016/j.janxdis.2006.01.004.
57. Ritz T, Meuret AE, Ayala ES. The psychophysiology of bloodinjection-injury phobia: looking beyond the diphasic responseparadigm. Int J Psychophysiol 2010;78:50-67. http://dx.doi.org/10.1016/j.ijpsycho.2010.05.007.
58. Newman BH, Graves S. A study of 178 consecutive vasovagal syncopal reactions from the perspective of safety. Transfusion 2001;41:1475-9. http://dx.doi.org/10.1046/j.1537-2995.2001.41121475.x.
59. Ditto B, Balegh S, Gilchrist PT, Holly CD. Relation between perceived blood loss and vasovagal symptoms in blood donors. Clin Auton Res 2012;22:113-6. http://dx.doi.org/10.1007/s10286-011-0147-1.
60. Babiloni C, Brancucci A, Capotosto P, Del Percio C, Romani GL, Arendt-Nielsen L, et al. Different modalities of painful somatosensory stimulations affect anticipatory cortical processes:a high-resolution EEG study. Brain Res Bull 2007;71:475-84. http://dx.doi.org/10.1016/j.brainresbull.2006.10.025.
61. Babiloni C, Brancucci A, Del Percio C, Capotosto P, Arendt-Nielsen L, Chen AC, et al. Anticipatory electroencephalography alpha rhythm predicts subjective perception of pain intensity. Pain 2006;7:709-17. http://dx.doi.org/10.1016/j.jpain.2006.03.005.
62. Holly CD, Torbit L, Ditto B. Applied tension and coping with blood donation:a randomized trial. Ann Behav Med 2012;43:173-80. http://dx.doi.org/10.1007/s12160-011-9315-8.
63. Ditto B, France CR, Lavoie P, Roussos M, Adler PS. Reducing reactions to blood donation with applied muscle tension:a randomized controlled trial. Transfusion 2003;43:1269-75. http://dx.doi.org/10.1046/j.1537-2995.2003.00488.x.
64. Usichenko TI, Pavlovic D, Foellner S, Wendt M. Reducing venipuncture pain by a cough trick:a randomized crossover volunteer study. Anesth Analg 2004;98:343-5. http://dx.doi.org/10.1213/01.ANE.0000094983.16741.AF.
65. Babiloni C, Brancucci A, Arendt-Nielsen L, Babiloni F, Capotosto P, Carducci F, et al. Attentional processes and cognitive performance during expectancy of painful galvanic stimulations:a high-resolution EEG study. Behav Brain Res 2004;152:137-47.
66. Del Percio C, Le Pera D, Arendt-Nielsen L, Babiloni C, Brancucci A, Chen AC, et al. Distraction affects frontal alpha rhythms related to expectancy of pain:an EEG study. Neuroimage 2006;31:1268-77. http://dx.doi.org/10.1016/j.neuroimage.2006.01.013.
67. MacLaren JE, Cohen LL. A comparison of distraction strategies for venipuncture distress in children. J Pediatr Psychol 2005;30:387-96. http://dx.doi.org/10.1093/jpepsy/jsi062
68. Bagnasco A, Pezzi E, Rosa F, Fornonil L, Sasso L. Distraction techniques in children during venipuncture:an Italian experience. J Prev Med Hyg 2012;53:44-8.
69. Szmuk P, Szmuk E, Ezri T. Use of needle-free injection systems to alleviate needle phobia and pain at injection. Expert Rev Pharmacoecon Outcomes Res 2005;5:467-77. http://dx.doi.org/10.1586/14737167.5.4.467
70. Galena HJ. Complications occurring from diagnostic venipuncture. J Fam Pract 1992;34:582-4.
71. Bhatti K, Ali S, Shamugan SK, Ward AS. True brachial artery aneurysm following blood donation:a case report of a rare complication. Eur J Vasc Endovasc Surg 2007;13:44-6.
72. Newman BH. Arterial puncture phlebotomy in whole-blood donors. Transfusion 2001;41:1390-2. http://dx.doi.org/10.1046/j.1537-2995.2001.41111390.x.
73. Howanitz PJ, Cembrowski GS, Bachner P. Laboratory phlebotomy. College of American Pathologists Q-Probe study of patient satisfaction and complications in 23,783 patients. Arch Pathol Lab Med 1991;115:867-72.
74. Ernst DJ, Ernst C. Phlebotomy tools of the trade: part 2: surveying the antecubital area. Home healthc nurse 2002;20:402-3. http://dx.doi.org/10.1097/00004045-200206000-00021.
75. Lee H, Lee SH, Kim SJ, Choi WI, Lee JH, Choi IJ. Variations of the cubital superficial vein investigated by using the intravenous illuminator. Anat Cell Bio 2015;48:62-5. http://dx.doi.org/10.5115/acb.2015.48.1.62
76. Berry PR, Wallis WE. Venepuncture nerve injuries. Lancet 1977;1:1236-7. http://dx.doi.org/10.1016/S0140-6736(77)92442-4.
77. Yamada K, Yamada K, Katsuda I, Hida T. Cubital fossa venipuncture sites based on anatomical variations and relationships of cutaneous veins and nerves. Clin Anat 2008;21:307-13. http://dx.doi.org/10.1002/ca.20622.
78. Rayegani SM, Azadi A. Lateral antebrachial cutaneous nerve injury induced by phlebotomy. J Brachial Plex Peripher Nerve Inj 2007;2:6.
79. Ramos JA. Venipuncture-related lateral antebrachial cutaneous nerve injury:what to know? Braz J Anesthesiol 2014;64:131-3. http://dx.doi.org/10.1016/j.bjane.2013.06.003.
80. Horowitz SH. Venipuncture-induced causalgia:anatomic relations of upper extremity superficial veins and nerves, and clinical considerations. Transfusion 2000;40:1036-40. http://dx.doi.org/10.1046/j.1537-2995.2000.40091036.x
81. Elahi F, Reddy CG. Venipuncture-induced complex regional pain syndrome:a case report and review of the literature. J Med Case Rep 2014; 20 14:613921.
82. Ohnishi H, Watanabe M, Watanabe T. Butterfly needles reduce the incidence of nerve injury during phlebotomy. Arch Pathol Lab Med 2012;136: 352. http://dx.doi.org/10.5858/arpa.2011-0431-LE.
83. Mikuni Y, Chiba S, Tonosaki Y. Topographical anatomy of superficial veins, cutaneous nerves, and arteries at venipuncture sites in the cubital fossa. Anat Sci Int 2013;88:46-57. http://dx.doi.org/10.1007/s12565-012-0160-z.
84. Sasaki S, Murakami N, Matsumura Y, Ichimura M, Mori M. Relationship between tourniquet pressure and a cross-section area of superficial vein of forearm. Acta Med Okayama 2012;66:67-71.
85. Ichimura M, Sasaki S, Mori M, Ogino T. Tapping but not massage enhances vasodilation and improves venous palpation of cutaneous veins. Acta Med Okayama 2015;69:79-85.
86. Miyake RK, Zeman HD, Duarte FH, Kikuchi R, Ramacciotti E, Lovhoiden G, et al. Vein imaging:a new method of near infrared imaging, where a processed image is projected onto the skin for the enhancement of vein treatment. Dermatol Surg 2006;32:1031-8.
87. Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Scartezini M, Guidi GC, et al. Transillumination:a new tool to eliminate the impact of venous stasis during the procedure for the collection of diagnostic blood specimens for routine haematological testing. Int J Lab Hematol 2011;33:457-62.
88. Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Manguera CL, Sumita NM, et al. New ways to deal with known preanalytical issues:use of transilluminator instead of tourniquet for easing vein access and eliminating stasis on clinical biochemistry. Biochem Med (Zagreb) 2011;21:152-9. http://dx.doi.org/10.11613/BM.2011.024
89. Ernst DJ, Ernst C. Phlebotomy tools of the trade: part 3: Alternative sites for drawing blood. Home healthc nurse. 2003;21:156-8. http://dx.doi.org/10.1097/00004045-200303000-00006.
90. Yoshida M, Shiiba S, Sago T, Nunomaki M, Harano N, Watanabe S. Comparison of pain tolerance thresholds of upper limb to identify the most appropriate venipuncture site. J Oral Maxillofac Surg 2015; 73:850 e1-5.
91. Clinical and Laboratory Standards Institute, Procedures for the Collection of Diagnostic Blood Specimens by Venipuncutre; Approved Standard-Sixth Edition. CLSI document H3-A5. Wayne, PA, USA, 2007.
92. World Health Organization (WHO) guidelines on drawing blood: best practices in phlebotomy: WHO Press; 2010. 125 p
93. Lippi G, Caputo M, Banfi G, Buttarello M, Ceriotti F, Daves M, et al. Raccomandazioni per il prelievo di sangue venoso. Bioch Clin 2008;32:6569-77.
94. Nikolac N, Supak-Smolcic V, Simundic AM, Celap I, Croatian Society of Medical B, Laboratory M. Croatian Society of Medical Biochemistry and Laboratory Medicine: national recommendations for venous blood sampling. Biochem Med (Zagreb) 2013;23:242-54. http://dx.doi.org/10.11613/BM.2013.031.
95. Plebani M. Errors in clinical laboratories or errors in laboratory medicine? Clin Chem Lab Med 2006;44:750-9. http://dx.doi.org/10.1515/CCLM.2006.123.
96. Lippi G, Guidi GC, Mattiuzzi C, Plebani M. Preanalytical variability:the dark side of the moon in laboratory testing. Clin Chem Lab Med 2006;44:358-65. http://dx.doi.org/10.1515/CCLM.2006.073.
97. Lippi G, Salvagno GL, Montagnana M, Franchini M, Guidi GC. Phlebotomy issues and quality improvement in results of laboratory testing. Clin Lab 2006;52:217-30.
98. Lippi G, Salvagno GL, Montagnana M, Franchini M, Guidi GC. Venous stasis and routine hematologic testing. Clin Lab Haematol 2006;28:332-7. http://dx.doi.org/10.1111/j.1365-2257.2006.00818.x.
99. Lippi G, Salvagno GL, Montagnana M, Guidi GC. Shortterm venous stasis influences routine coagulation testing. Blood Coagul Fibrinolysis 2005;16:453-8. http://dx.doi.org/10.1097/01.mbc.0000178828.59866.03.
100. Lima-Oliveira G, Lippi G, Salvagno GL, Gaino S, Poli G, Gelati M, et al. Venous stasis and whole blood platelet aggregometry:a question of data reliability and patient safety. Blood Coagul Fibrinolysis 2015;26:665-8. http://dx.doi.org/10.1097/MBC.0000000000000342.
101. Lippi G, Salvagno GL, Montagnana M, Brocco G, Guidi GC. Influence of short-term venous stasis on clinical chemistry testing. Clin Chem Lab Med 2005;43:869-75. http://dx.doi.org/10.1515/CCLM.2005.146.
102. Seimiya M, Yoshida T, Sawabe Y, Sogawa K, Umemura H, Matsushita K, et al. Reducing the incidence of pseudohyperkalemia by avoiding making a fist during phlebotomy:a quality improvement report. Am J Kidney Dis 2010;56:686-92. http://dx.doi.org/10.1053/j.ajkd.2010.06.014.
103. Lippi G, Salvagno GL, Montagnana M, Poli G, Guidi GC. Influence of the needle bore size on platelet count and routine coagulation testing. Blood Coagul Fibrinolysis 2006;17:557-61. http://dx.doi.org/10.1097/01.mbc.0000245300.10387.ca.
104. Lippi G, Salvagno GL, Montagnana M, Brocco G, Cesare Guidi G. Influence of the needle bore size used for collecting venous blood samples on routine clinical chemistry testing. Clin Chem Lab Med 2006;44:1009-14. http://dx.doi.org/10.1515/CCLM.2006.172.
105. Asirvatham JR, Moses V, Bjornson L. Errors in potassium measurement:a laboratory perspective for the clinician. North Am J Med Sci 2013;5:255-9. http://dx.doi.org/10.4103/1947-2714.110426.
106. Sevastos N, Theodossiades G, Archimandritis AJ. Pseudohyperkalemia in serum:a new insight into an old phenomenon. Clin Med Res 2008; 6: 30-2. http://dx.doi.org/10.3121/cmr.2008.739.
107. Stankovic AK, Smith S. Elevated serum potassium values:the role of preanalytic variables. Am J Clin Pathol 2004;121:S105-S12.
108. Cornes MP, Ford C, Gama R. Spurious hyperkalaemia due to EDTA contamination: common and not always easy to identify. Ann Clin Biochem 2008;45:601-3. http://dx.doi.org/10.1258/acb.2008.007241.
109. Sulaiman RA, Cornes MP, Whitehead SJ, Othonos N, Ford C, Gama R. Effect of order of draw of blood samples during phlebotomy on routine biochemistry results. J Clin Pathol 2011;64:1019-20. http://dx.doi.org/10.1136/jclinpath-2011-200206.
110. Salvagno G, Lima-Oliveira G, Brocco G, Danese E, Guidi GC, Lippi G. The order of draw:myth or science? Clin Chem Lab Med 2013;51:2281-5. http://dx.doi.org/10.1515/cclm-2013-0412.
111. Lima-Oliveira G, Lippi G, Salvagno GL, Brocco G, Gaino S, Dima F, et al. Processing of diagnostic blood specimens: is it really necessary to mix primary blood tubes after collection with evacuated tube system? Biopreserv Biobank 2014;12:53-9. http://dx.doi.org/10.1089/bio.2013.0043.
112. Naguib MT, Evans N. Combined false hyperkalemia and hypocalcemia due to specimen contamination during routine phlebotomy. South Med J 2002;95:1218-20. http://dx.doi.org/10.1097/00007611-200295100-00025.
113. Lima-Oliveira G, Salvagno GL, Danese E, Favaloro EJ, Guidi GC, Lippi G. Sodium citrate blood contamination by K2-ethylenediaminetetraacetic acid (EDTA):impact on routine coagulation testing. Int J Lab Hematol 2015;37:403-9. http://dx.doi.org/10.1111/ijlh.12301.
114. Lima-Oliveira G, Salvagno GL, Danese E, Brocco G, Guidi GC, Lippi G. Contamination of lithium heparin blood by K2-ethylenediaminetetraacetic acid (EDTA): an experimental evaluation. Biochem Med (Zagreb) 2014; 24:359-67. http://dx.doi.org/10.11613/BM.2014.038.
115. Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Incorrect order of draw could be mitigate the patient safety:a phlebotomy management case report. Biochem Med (Zagreb) 2013;23:218-23. http://dx.doi.org/10.11613/BM.2013.026.
116. Lippi G, Salvagno GL, Montagnana M, Brocco G, Guidi GC. Influence of hemolysis on routine clinical chemistry testing. Clin Chem Lab Med 2006;44:311-6. http://dx.doi.org/10.1515/CCLM.2006.054.
117. Lippi G, Blanckaert N, Bonini P, Green S, Kitchen S, Palicka V, et al. Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories. Clin Chem Lab Med 2008;46:764-72. http://dx.doi.org/10.1515/CCLM.2008.170.
118. Wollowitz A, Bijur PE, Esses D, John Gallagher E. Use of butterfly needles to draw blood is independently associated with marked reduction in hemolysis compared to intravenous catheter. Acad Emerg Med 2013;20:1151-5. http://dx.doi.org/10.1111/acem.12245.
119. Heyer NJ, Derzon JH, Winges L, Shaw C, Mass D, Snyder SR, et al. Effectiveness of practices to reduce blood sample hemolysis in EDs:a laboratory medicine best practices systematic review and meta-analysis. Clin Biochem 2012;45:1012-32. http://dx.doi.org/10.1016/j.clinbiochem.2012.08.002.
120. Koseoglu M, Hur A, Atay A, Cuhadar S. Effects of hemolysis interferences on routine biochemistry parameters. Biochem Med (Zagreb) 2011;21:79-85. http://dx.doi.org/10.11613/BM.2011.015.
121. Lippi G, Pavesi F, Cattabiani C, Avanzini P, Pipitone S. Influence of in vitro hemolysis on nucleated red blood cells and reticulocyte counts. Int J Lab Hematol 2013;35:225-8. http://dx.doi.org/10.1111/ijlh.12012.
122. Salvagno GL, Danese E, Lima-Oliveira G, Guidi GC, Lippi G. Avoidance to wipe alcohol before venipuncture is not a source of spurious hemolysis. Biochem Med 2013;23:201-5. http://dx.doi.org/10.11613/BM.2013.023.
123. Lippi G, Pipitone S, Gennari D, Franchini M. Identification of spurious hemolysis in anticoagulated blood with Sysmex XE-2100 and Siemens Advia 2120. Clin Lab 2012;58:801-4.
124. Lippi G, Pavesi F, Avanzini P, Chetta F, Aloe R, Pipitone S. Development of simple equations for effective screening of spurious hemolysis in whole-blood specimens. Int J Lab Hematol 2015;37:253-8. http://dx.doi.org/10.1111/ijlh.12277.
125. Bonini P, Plebani M, Ceriotti F, Rubboli F. Errors in laboratory medicine. Clin Chem 2002;48:691-8.
126. Carraro P, Plebani M. Errors in a stat laboratory:types and frequencies 10 years later. Clin Chem 2007;53:1338-42. http://dx.doi.org/10.1515/cclm-2014-1053.
127. Simundic AM, Church S, Cornes MP, Grankvist K, Lippi G, Nybo M, et al. Compliance of blood sampling procedures with the CLSI H3-A6 guidelines: An observational study by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) working group for the preanalytical phase (WG-PRE). Clin Chem Lab Med 2015;53:1321-31. http://dx.doi.org/10.1515/cclm-2014-1053.
128. Lillo R, Salinas M, Lopez-Garrigos M, Naranjo-Santana Y, Gutierrez M, Marin MD, et al. Reducing preanalytical laboratory sample errors through educational and technological interventions. Clin Lab 2012;58:911-7.
129. Lippi G, Salvagno GL, Lima-Oliveira G, Brocco G, Danese E, Guidi GC. Postural change during venous blood collection is a major source of bias in clinical chemistry testing. Clin Chim Acta 2015;440:164-8. http://dx.doi.org/10.1016/j.cca.2014.11.024.
130. Lippi G, Salvagno GL, Lima-Oliveira G, Danese E, Favaloro EJ, Guidi GC. Influence of posture on routine hemostasis testing. Blood Coagul Fibrinolysis 2015;26:716-9. http://dx.doi.org/10.1097/MBC.0000000000000326.
131. Jacob G, Raj SR, Ketch T, Pavlin B, Biaggioni I, Ertl AC, et al. Postural pseudoanemia:posture-dependent change in hematocrit. Mayo Clin Proc 2005;80:611-4. http://dx.doi.org/10.4065/80.5.611.
132. Vuk T, Cipek V, Jukic I. Blood collection staff education in the prevention of venepuncture failures and donor adverse reactions:from inexperienced to skilful staff. Blood transfus 2015;13:338-9.