Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

Molecular Neurobiology

Volumn 54, Issue 2, 2017, Pages 1552-1563

  Machado, Nuno J ^a   Simões, Ana Patrícia ^a   Silva, Henrique B ^a   Ardais, Ana Paula ^a,b   Kaster, Manuella P ^a   Garção, Pedro ^a   Rodrigues, Diana I ^a   Pochmann, Daniela ^a,b   Santos, Ana Isabel ^a   Araújo, Inês M ^a,c   Porciúncula, Lisiane O ^b   Tomé, Ângelo R ^a,d   Köfalvi, Attila ^a   Vaugeois, Jean Marie ^e   Agostinho, Paula ^a,f   El Yacoubi, Malika ^g,h   Cunha, Rodrigo A ^a,f   Gomes, Catarina A ^a,f  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSITY OF ALGARVE   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITÉ DE ROUEN   (France)

^f UNIVERSITY OF COIMBRA   (Portugal)

^g LYON NEUROSCIENCE RESEARCH CENTER   (France)

^h UNIVERSITÉ LYON 1   (France)

Author keywords

Adenosine A2A receptors; Caffeine; Depression; Glutamate release; Memory; Synaptic plasticity

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; CAFFEINE; GLUTAMIC ACID; SYNAPSE RECEPTOR; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; CENTRAL STIMULANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ANXIETY DISORDER; ARTICLE; BRAIN FUNCTION; CHRONIC STRESS; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; DIETARY INTAKE; FORCED SWIM TEST; GLUTAMATERGIC SYNAPSE; HIPPOCAMPUS; INFANT; MALE; MAZE TEST; MEMORY DISORDER; MOOD DISORDER; MOUSE; MOUSE STRAIN; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; RECEPTOR UPREGULATION; TAIL SUSPENSION TEST; Y-MAZE TEST; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SPECIES DIFFERENCE; SYNAPSE; UPREGULATION;

ANIMALS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; HIPPOCAMPUS; MALE; MEMORY DISORDERS; MICE; MOOD DISORDERS; RECEPTOR, ADENOSINE A2A; SPECIES SPECIFICITY; SYNAPSES; UP-REGULATION;

EID: 84957698500     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9774-9     Document Type: Article

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