Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 25, 2015, Pages 7833-7838

  Kaster, Manuella P ^a,b   Machado, Nuno J ^a   Silva, Henrique B ^a   Nunes, Ana ^a   Ardais, Ana Paula ^a,c   Santana, Magda ^a   Baqi, Younis ^d,e   Müller, Christa E ^d   Rodrigues, Ana Lúcia S ^b   Porciúncula, Lisiane O ^c   Chen, Jiang Fan ^f   Tomé, Ângelo R ^a,g   Agostinho, Paula ^a,h   Canas, Paula M ^a   Cunha, Rodrigo A ^a,h  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d UNIVERSITY OF BONN   (Germany)

^e SULTAN QABOOS UNIVERSITY   (Oman)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF COIMBRA   (Portugal)

^h UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Adenosine A2a receptor; Caffeine; Chronic stress; Mood dysfunction; Synaptic dysfunction

Indexed keywords

ADENOSINE A2A RECEPTOR; CAFFEINE; ISTRADEFYLLINE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN; VESICULAR GLUTAMATE TRANSPORTER 1;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR CHANGE; BRAIN NERVE CELL; CHRONIC UNPREDICTABLE STRESS; CONTROLLED STUDY; HIPPOCAMPUS; MEMORY DISORDER; MOOD DISORDER; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; COMPLICATION; DRUG EFFECTS; MALE; MEMORY DISORDERS; MENTAL STRESS; METABOLISM; MOOD DISORDERS; NERVE CELL;

MUS;

ANIMALS; CAFFEINE; MALE; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MOOD DISORDERS; NEURONS; RECEPTOR, ADENOSINE A2A; STRESS, PSYCHOLOGICAL;

EID: 84934894606     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1423088112     Document Type: Article

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