FGF2 inhibits endothelial-mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-β signaling

Journal of Cell Science

Volumn 129, Issue 3, 2016, Pages 569-579

  Correia, Ana C P ^a,b   Moonen, Jan Renier A J ^a   Brinker, Marja G L ^a   Krenning, Guido ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

EndMT; Endothelial cell; Endothelial dysfunction; Endothelial mesenchymal transition; FGF; Fibroblast growth factor; MicroRNA; MiRNA; TGF ; Transforming growth factor beta

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; MICRORNA 20A; SMAD ANCHOR FOR RECEPTOR ACTIVATION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSGELIN; VASCULAR ENDOTHELIAL CADHERIN; BIOLOGICAL MARKER; CADHERIN; LEUKOCYTE ANTIGEN; MICRORNA; MIRN20 MICRORNA, HUMAN; PROTEIN SERINE THREONINE KINASE; SERINE PROTEINASE; SIGNAL PEPTIDE; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; ZFYVE16 PROTEIN, HUMAN;

ARTICLE; CELL FUNCTION; CELL TRANSFORMATION; CONTROLLED STUDY; ECTOPIC EXPRESSION; ENDOTHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERTROPHY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; CELL CULTURE; CELL TRANSDIFFERENTIATION; ENDOTHELIUM CELL; HEK293 CELL LINE; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY;

ANTIGENS, CD; BIOMARKERS; CADHERINS; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STROMAL CELLS; MICRORNAS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84957694571     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.176248     Document Type: Article

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