Activated phosphatidylinositol 3-kinase/akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling

Cellular Physiology and Biochemistry

Volumn 35, Issue 4, 2015, Pages 1643-1653

  Zhang, Zongqi ^a   Zhang, Tiantian ^a   Zhou, Yaoyao ^a   Wei, Xiaowei ^a   Zhu, Jianbing ^a   Zhang, Junfeng ^a   Wang, Changqian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Endothelial progenitor cell; Endothelial to mesenchymal transition; FoxO3a; Phosphatidylinositol 3 kinase; PIK3R2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA SMOOTH MUSCLE ACTIN; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; SMAD3 PROTEIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR FKHRL1; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACTIN; ACTIN BINDING PROTEIN; CHROMONE DERIVATIVE; FORKHEAD TRANSCRIPTION FACTOR; FOXO3A PROTEIN, RAT; MORPHOLINE DERIVATIVE; MUSCLE PROTEIN; PROTEIN SUBUNIT; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL ISOLATION; CELL TRANSFORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; ENDOTHELIAL MESENCHYMAL TRANSITION; ENDOTHELIAL PROGENITOR CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE MICROSCOPY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHOSPHORYLATION; PROTEIN SUBUNIT; RNA INTERFERENCE; SPRAGUE DAWLEY RAT;

RATTUS;

ACTINS; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMONES; ENDOTHELIAL PROGENITOR CELLS; FORKHEAD TRANSCRIPTION FACTORS; INSULIN-LIKE GROWTH FACTOR I; MALE; MESENCHYMAL STROMAL CELLS; MICROFILAMENT PROTEINS; MORPHOLINES; MUSCLE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84926319567     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000373978     Document Type: Article

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