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Volumn 98, Issue , 2016, Pages 159-169

Nanoparticle-siRNA: A potential cancer therapy?

Author keywords

Cancer Therapy; Nano drugs; Nanoparticles; RNAi; SiRNA

Indexed keywords

MESSENGER RNA; NANOPARTICLE; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT;

EID: 84957634220     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2015.10.015     Document Type: Review
Times cited : (129)

References (99)
  • 1
    • 84938364026 scopus 로고    scopus 로고
    • Nanoparticles: cellular uptake and cytotoxicity
    • Springer, Netherlands, D.G. Capco, Y. Chen (Eds.)
    • Adjei I., Sharma B., Labhasetwar V. Nanoparticles: cellular uptake and cytotoxicity. Nanomaterial 2014, 73-91. Springer, Netherlands. D.G. Capco, Y. Chen (Eds.).
    • (2014) Nanomaterial , pp. 73-91
    • Adjei, I.1    Sharma, B.2    Labhasetwar, V.3
  • 2
    • 80155151294 scopus 로고    scopus 로고
    • Nanodiamond as a vector for siRNA delivery to ewing sarcoma cells
    • Alhaddad A., et al. Nanodiamond as a vector for siRNA delivery to ewing sarcoma cells. Small 2011, 7(21):3087-3095.
    • (2011) Small , vol.7 , Issue.21 , pp. 3087-3095
    • Alhaddad, A.1
  • 3
    • 84927920630 scopus 로고    scopus 로고
    • Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy
    • An S., et al. Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy. Biomaterials 2015, 53(0):330-340.
    • (2015) Biomaterials , vol.53 , pp. 330-340
    • An, S.1
  • 4
    • 84930370179 scopus 로고    scopus 로고
    • Polymeric siRNA delivery vectors: knocking down cancers with polymeric-based gene delivery systems
    • Ardana A., et al. Polymeric siRNA delivery vectors: knocking down cancers with polymeric-based gene delivery systems. J. Chem. Technol. Biotechnol. 2015, 90(7):1196-1208.
    • (2015) J. Chem. Technol. Biotechnol. , vol.90 , Issue.7 , pp. 1196-1208
    • Ardana, A.1
  • 5
    • 77955329314 scopus 로고    scopus 로고
    • Effect of nanoparticle surface charge at the plasma membrane and beyond
    • Arvizo R.R., et al. Effect of nanoparticle surface charge at the plasma membrane and beyond. Nano Lett. 2010, 10(7):2543-2548.
    • (2010) Nano Lett. , vol.10 , Issue.7 , pp. 2543-2548
    • Arvizo, R.R.1
  • 6
    • 84904055887 scopus 로고    scopus 로고
    • Combination of anti-angiogenic therapies reduces osteolysis and tumor burden in experimental breast cancer bone metastasis
    • Bachelier R., et al. Combination of anti-angiogenic therapies reduces osteolysis and tumor burden in experimental breast cancer bone metastasis. Int. J. Cancer 2014, 135(6):1319-1329.
    • (2014) Int. J. Cancer , vol.135 , Issue.6 , pp. 1319-1329
    • Bachelier, R.1
  • 7
    • 84923531054 scopus 로고    scopus 로고
    • Understanding nanoparticle cellular entry: a physicochemical perspective
    • Beddoes C.M., Case C.P., Briscoe W.H. Understanding nanoparticle cellular entry: a physicochemical perspective. Adv. Colloid Interface Sci. 2015, 218(0):48-68.
    • (2015) Adv. Colloid Interface Sci. , vol.218 , pp. 48-68
    • Beddoes, C.M.1    Case, C.P.2    Briscoe, W.H.3
  • 8
    • 84889054807 scopus 로고    scopus 로고
    • Polymer functionalized single walled carbon nanotubes mediated drug delivery of gliotoxin in cancer cells
    • Bhatnagar I., Venkatesan J., Kim S.-K. Polymer functionalized single walled carbon nanotubes mediated drug delivery of gliotoxin in cancer cells. J. Biomed. Nanotechnol. 2014, 10(1):120-130.
    • (2014) J. Biomed. Nanotechnol. , vol.10 , Issue.1 , pp. 120-130
    • Bhatnagar, I.1    Venkatesan, J.2    Kim, S.-K.3
  • 9
    • 79952487660 scopus 로고    scopus 로고
    • Inorganic nanoparticles in cancer therapy
    • Bhattacharyya S., et al. Inorganic nanoparticles in cancer therapy. Pharmaceutical Res. 2011, 28(2):237-259.
    • (2011) Pharmaceutical Res. , vol.28 , Issue.2 , pp. 237-259
    • Bhattacharyya, S.1
  • 10
    • 84898539186 scopus 로고    scopus 로고
    • Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors
    • Bhujbal S.V., de Vos P., Niclou S.P. Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors. Adv. Drug Deliv. Rev. 2014, 67-68(0):142-153.
    • (2014) Adv. Drug Deliv. Rev. , pp. 142-153
    • Bhujbal, S.V.1    de Vos, P.2    Niclou, S.P.3
  • 11
    • 84899492527 scopus 로고    scopus 로고
    • Physicochemical characteristics of nanomaterials that affect pulmonary inflammation
    • Braakhuis H.M., et al. Physicochemical characteristics of nanomaterials that affect pulmonary inflammation. Part. Fibre Toxicol. 2014, 11(18):1-25.
    • (2014) Part. Fibre Toxicol. , vol.11 , Issue.18 , pp. 1-25
    • Braakhuis, H.M.1
  • 12
    • 85047694081 scopus 로고    scopus 로고
    • VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs
    • Cao Y. VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs. Nat. Rev. Endocrinol. 2014, 10(9):530-539.
    • (2014) Nat. Rev. Endocrinol. , vol.10 , Issue.9 , pp. 530-539
    • Cao, Y.1
  • 13
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology 2005, 69(Suppl. 3):4-10.
    • (2005) Oncology , vol.69 , pp. 4-10
    • Carmeliet, P.1
  • 14
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D., Rossi J.J. The promises and pitfalls of RNA-interference-based therapeutics. Nature 2009, 457(7228):426-433.
    • (2009) Nature , vol.457 , Issue.7228 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 15
    • 77956269093 scopus 로고    scopus 로고
    • Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
    • Chen Y., et al. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol. Ther. 2010, 18(9):1650-1656.
    • (2010) Mol. Ther. , vol.18 , Issue.9 , pp. 1650-1656
    • Chen, Y.1
  • 16
    • 84892667514 scopus 로고    scopus 로고
    • Biodegradable cationic polymeric nanocapsules for overcoming multidrug resistance and enabling drug-gene co-delivery to cancer cells
    • Chen C.-K., et al. Biodegradable cationic polymeric nanocapsules for overcoming multidrug resistance and enabling drug-gene co-delivery to cancer cells. Nanoscale 2014, 6(3):1567-1572.
    • (2014) Nanoscale , vol.6 , Issue.3 , pp. 1567-1572
    • Chen, C.-K.1
  • 17
    • 78651314500 scopus 로고    scopus 로고
    • Potential clinical applications of siRNA technique: benefits and limitations
    • Chen S.-H. Potential clinical applications of siRNA technique: benefits and limitations. Eur. J. Clin. Investig. 2011, 41(2):221-232.
    • (2011) Eur. J. Clin. Investig. , vol.41 , Issue.2 , pp. 221-232
    • Chen, S.-H.1
  • 18
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • Chithrani B.D., Ghazani A.A., Chan W.C.W. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 2006, 6(4):662-668.
    • (2006) Nano Lett. , vol.6 , Issue.4 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 20
    • 78649315943 scopus 로고    scopus 로고
    • To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
    • Danhier F., Feron O., Préat V. To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J. Control. Release 2010, 148(2):135-146.
    • (2010) J. Control. Release , vol.148 , Issue.2 , pp. 135-146
    • Danhier, F.1    Feron, O.2    Préat, V.3
  • 21
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • Davis M.E., et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010, 464(7291):1067-1070.
    • (2010) Nature , vol.464 , Issue.7291 , pp. 1067-1070
    • Davis, M.E.1
  • 22
    • 29244434509 scopus 로고    scopus 로고
    • Gold colloid analysis by inductively coupled plasma-mass spectrometry in a single particle mode
    • Degueldre C., Favarger P.Y., Wold S. Gold colloid analysis by inductively coupled plasma-mass spectrometry in a single particle mode. Anal. Chim. Acta 2006, 555(2):263-268.
    • (2006) Anal. Chim. Acta , vol.555 , Issue.2 , pp. 263-268
    • Degueldre, C.1    Favarger, P.Y.2    Wold, S.3
  • 23
    • 84893909299 scopus 로고    scopus 로고
    • Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies
    • Deng Y., et al. Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies. Gene 2014, 538(2):217-227.
    • (2014) Gene , vol.538 , Issue.2 , pp. 217-227
    • Deng, Y.1
  • 24
    • 36749074982 scopus 로고    scopus 로고
    • Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference
    • Desigaux L., et al. Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference. Proc. Natl. Acad. Sci. 2007, 104(42):16534-16539.
    • (2007) Proc. Natl. Acad. Sci. , vol.104 , Issue.42 , pp. 16534-16539
    • Desigaux, L.1
  • 25
    • 84901656939 scopus 로고    scopus 로고
    • The new world of RNAs
    • Dogini D.B., et al. The new world of RNAs. Genet. Mol. Biol. 2014, 37(Suppl. 1):285-293.
    • (2014) Genet. Mol. Biol. , vol.37 , pp. 285-293
    • Dogini, D.B.1
  • 26
    • 0033973070 scopus 로고    scopus 로고
    • Phase I. Clinical trial design in cancer drug development
    • Eisenhauer E.A., et al. Phase I. Clinical trial design in cancer drug development. J. Clin. Oncol. 2000, 684.
    • (2000) J. Clin. Oncol. , pp. 684
    • Eisenhauer, E.A.1
  • 27
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang J., Nakamura H., Maeda H. The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv. Drug Deliv. Rev. 2011, 63(3):136-151.
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , Issue.3 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 28
    • 84900400291 scopus 로고    scopus 로고
    • Drug delivery vehicles on a nano-engineering perspective
    • Felice B., et al. Drug delivery vehicles on a nano-engineering perspective. Mater. Sci. Eng. C 2014, 41(0):178-195.
    • (2014) Mater. Sci. Eng. C , vol.41 , pp. 178-195
    • Felice, B.1
  • 29
    • 84897914852 scopus 로고    scopus 로고
    • Synergistic inhibition of breast cancer by co-delivery of VEGF siRNA and paclitaxel via vapreotide-modified core-shell nanoparticles
    • Feng Q., et al. Synergistic inhibition of breast cancer by co-delivery of VEGF siRNA and paclitaxel via vapreotide-modified core-shell nanoparticles. Biomaterials 2014, 35(18):5028-5038.
    • (2014) Biomaterials , vol.35 , Issue.18 , pp. 5028-5038
    • Feng, Q.1
  • 30
    • 84926108132 scopus 로고    scopus 로고
    • RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model
    • Gillespie David L., et al. RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model. J. Neurosurg. 2015, 122(2):331-341.
    • (2015) J. Neurosurg. , vol.122 , Issue.2 , pp. 331-341
    • Gillespie, D.L.1
  • 31
    • 84897107483 scopus 로고    scopus 로고
    • Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology
    • Gomes-da-Silva L., Simões S., Moreira J. Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology. Cell. Mol. Life Sci. 2014, 71(8):1417-1438.
    • (2014) Cell. Mol. Life Sci. , vol.71 , Issue.8 , pp. 1417-1438
    • Gomes-da-Silva, L.1    Simões, S.2    Moreira, J.3
  • 32
    • 34547653668 scopus 로고    scopus 로고
    • Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines
    • Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J. Drug Target 2007, 15(7-8):457-464.
    • (2007) J. Drug Target , vol.15 , Issue.7-8 , pp. 457-464
    • Greish, K.1
  • 33
    • 84923652247 scopus 로고    scopus 로고
    • Multidimensional effects of biologically synthesized silver nanoparticles in Helicobacter pylori, Helicobacter felis, and human lung (L132) and lung carcinoma A549 cells
    • Gurunathan S., et al. Multidimensional effects of biologically synthesized silver nanoparticles in Helicobacter pylori, Helicobacter felis, and human lung (L132) and lung carcinoma A549 cells. Nanoscale Res. Lett. 2015, 10. p. 35.
    • (2015) Nanoscale Res. Lett. , vol.10 , pp. 35
    • Gurunathan, S.1
  • 34
    • 84866372203 scopus 로고    scopus 로고
    • Formulation approaches to short interfering RNA and MicroRNA: challenges and implications
    • Guzman-Villanueva D., et al. Formulation approaches to short interfering RNA and MicroRNA: challenges and implications. J. Pharm. Sci. 2012, 101(11):4046-4066.
    • (2012) J. Pharm. Sci. , vol.101 , Issue.11 , pp. 4046-4066
    • Guzman-Villanueva, D.1
  • 35
    • 0032435099 scopus 로고    scopus 로고
    • Postmarketing drug surveillance: an epidemiologic approach
    • Hennessy S. Postmarketing drug surveillance: an epidemiologic approach. Clin. Ther. 1998, 20(Suppl. 3 (0)):C32-C39.
    • (1998) Clin. Ther. , vol.20 , pp. C32-C39
    • Hennessy, S.1
  • 36
    • 84885125168 scopus 로고    scopus 로고
    • The pH-controlled nanoparticles size of polydopamine for anti-cancer drug delivery
    • Ho C.-C. The pH-controlled nanoparticles size of polydopamine for anti-cancer drug delivery. J. Mater. Sci. Mater. Med. 2013, 24(10):2381-2390.
    • (2013) J. Mater. Sci. Mater. Med. , vol.24 , Issue.10 , pp. 2381-2390
    • Ho, C.-C.1
  • 37
    • 84884252848 scopus 로고    scopus 로고
    • Role of nanoparticle geometry in endocytosis: laying down to stand up
    • Huang C., et al. Role of nanoparticle geometry in endocytosis: laying down to stand up. Nano Lett. 2013, 13(9):4546-4550.
    • (2013) Nano Lett. , vol.13 , Issue.9 , pp. 4546-4550
    • Huang, C.1
  • 38
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability and retention effect for tumor targeting
    • Iyer A.K., et al. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discov. Today 2006, 11(17-18):812-818.
    • (2006) Drug Discov. Today , vol.11 , Issue.17-18 , pp. 812-818
    • Iyer, A.K.1
  • 39
    • 84904903436 scopus 로고    scopus 로고
    • The baffling human body and the boundless nanomaterial boon-a trap for cancer crab
    • Jeelani S., et al. The baffling human body and the boundless nanomaterial boon-a trap for cancer crab. J. Clin. Diagn. Res.: JCDR 2014, 8(7):ZE12.
    • (2014) J. Clin. Diagn. Res.: JCDR , vol.8 , Issue.7 , pp. ZE12
    • Jeelani, S.1
  • 40
    • 84886261520 scopus 로고    scopus 로고
    • Delivery materials for siRNA therapeutics
    • Kanasty R., et al. Delivery materials for siRNA therapeutics. Nat. Mater. 2013, 12(11):967-977.
    • (2013) Nat. Mater. , vol.12 , Issue.11 , pp. 967-977
    • Kanasty, R.1
  • 41
    • 84921030166 scopus 로고    scopus 로고
    • Therapeutic potential of siRNA and DNAzymes in cancer
    • Karnati H., et al. Therapeutic potential of siRNA and DNAzymes in cancer. Tumor Biol. 2014, 35(10):9505-9521.
    • (2014) Tumor Biol. , vol.35 , Issue.10 , pp. 9505-9521
    • Karnati, H.1
  • 42
    • 42549168945 scopus 로고    scopus 로고
    • Measuring sub nanometre sizes using dynamic light scattering
    • Kaszuba M., et al. Measuring sub nanometre sizes using dynamic light scattering. J. Nanopart. Res. 2008, 10(5):823-829.
    • (2008) J. Nanopart. Res. , vol.10 , Issue.5 , pp. 823-829
    • Kaszuba, M.1
  • 43
    • 33749844509 scopus 로고    scopus 로고
    • Development and characterisation of chitosan nanoparticles for siRNA delivery
    • Katas H., Alpar H.O. Development and characterisation of chitosan nanoparticles for siRNA delivery. J. Control. Release 2006, 115(2):216-225.
    • (2006) J. Control. Release , vol.115 , Issue.2 , pp. 216-225
    • Katas, H.1    Alpar, H.O.2
  • 44
    • 84921711123 scopus 로고    scopus 로고
    • Improving drug delivery to solid tumors: Priming the tumor microenvironment
    • Khawar I.A., Kim J.H., Kuh H.-J. Improving drug delivery to solid tumors: Priming the tumor microenvironment. J. Control. Release 2015, 201(0):78-89.
    • (2015) J. Control. Release , vol.201 , pp. 78-89
    • Khawar, I.A.1    Kim, J.H.2    Kuh, H.-J.3
  • 45
    • 84890453749 scopus 로고    scopus 로고
    • Applications of inorganic nanoparticles as therapeutic agents
    • Kim T. Applications of inorganic nanoparticles as therapeutic agents. Nanotechnology 2014, 25(1):012001.
    • (2014) Nanotechnology , vol.25 , Issue.1 , pp. 012001
    • Kim, T.1
  • 46
    • 84890506078 scopus 로고    scopus 로고
    • Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems
    • Kraft J.C., et al. Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems. J. Pharm. Sci. 2014, 103(1):29-52.
    • (2014) J. Pharm. Sci. , vol.103 , Issue.1 , pp. 29-52
    • Kraft, J.C.1
  • 47
    • 23044506285 scopus 로고    scopus 로고
    • Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering rna delivery
    • Landen C.N., et al. Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering rna delivery. Cancer Res. 2005, 65(15):6910-6918.
    • (2005) Cancer Res. , vol.65 , Issue.15 , pp. 6910-6918
    • Landen, C.N.1
  • 48
    • 84880144292 scopus 로고    scopus 로고
    • Recent developments in nanoparticle-based siRNA delivery for cancer therapy
    • Lee J.-M., Yoon T.-J., Cho Y.-S. Recent developments in nanoparticle-based siRNA delivery for cancer therapy. BioMed. Res. Int. 2013, p. 10.
    • (2013) BioMed. Res. Int. , pp. 10
    • Lee, J.-M.1    Yoon, T.-J.2    Cho, Y.-S.3
  • 49
    • 84888582862 scopus 로고    scopus 로고
    • Thermal stability of DNA functionalized gold nanoparticles
    • Li F., et al. Thermal stability of DNA functionalized gold nanoparticles. Bioconjug. Chem. 2013, 24(11):1790-1797.
    • (2013) Bioconjug. Chem. , vol.24 , Issue.11 , pp. 1790-1797
    • Li, F.1
  • 50
    • 84904883854 scopus 로고    scopus 로고
    • Development of RNA interference-based therapeutics and application of multi-target small interfering RNAs
    • Li T., et al. Development of RNA interference-based therapeutics and application of multi-target small interfering RNAs. Nucleic Acid Ther. 2014, 24(4):302-312.
    • (2014) Nucleic Acid Ther. , vol.24 , Issue.4 , pp. 302-312
    • Li, T.1
  • 51
    • 84876550866 scopus 로고    scopus 로고
    • Size and shape effects on receptor-mediated endocytosis of nanoparticles
    • Li X. Size and shape effects on receptor-mediated endocytosis of nanoparticles. J. Appl. Phys. 2012, 111(2):024702.
    • (2012) J. Appl. Phys. , vol.111 , Issue.2 , pp. 024702
    • Li, X.1
  • 52
    • 24644431865 scopus 로고    scopus 로고
    • 2 nanoparticles in the preconcentration of trace chromium and lead from sample solution and determination by inductively coupled plasma atomic emission spectrometry
    • 2 nanoparticles in the preconcentration of trace chromium and lead from sample solution and determination by inductively coupled plasma atomic emission spectrometry. Microchim. Acta 2005, 151(1-2):81-88.
    • (2005) Microchim. Acta , vol.151 , Issue.1-2 , pp. 81-88
    • Lian, N.1
  • 54
    • 84896875667 scopus 로고    scopus 로고
    • Multifunctional pH-sensitive polymeric nanoparticles for theranostics evaluated experimentally in cancer
    • Liu Y., et al. Multifunctional pH-sensitive polymeric nanoparticles for theranostics evaluated experimentally in cancer. Nanoscale 2014, 6(6):3231-3242.
    • (2014) Nanoscale , vol.6 , Issue.6 , pp. 3231-3242
    • Liu, Y.1
  • 55
    • 55949126429 scopus 로고    scopus 로고
    • Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats
    • Longmire M., Choyke P.L., Kobayashi H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine 2008, 3(5):703-717.
    • (2008) Nanomedicine , vol.3 , Issue.5 , pp. 703-717
    • Longmire, M.1    Choyke, P.L.2    Kobayashi, H.3
  • 56
    • 10844277454 scopus 로고    scopus 로고
    • RNA polymer translocation with single-walled carbon nanotubes
    • Lu Q., et al. RNA polymer translocation with single-walled carbon nanotubes. Nano Lett. 2004, 4(12):2473-2477.
    • (2004) Nano Lett. , vol.4 , Issue.12 , pp. 2473-2477
    • Lu, Q.1
  • 57
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • Maeda H., Bharate G.Y., Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur. J. Pharm. Biopharm. 2009, 71(3):409-419.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , Issue.3 , pp. 409-419
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 58
    • 84901745389 scopus 로고    scopus 로고
    • The drug discovery by nanomedicine and its clinical experience
    • Matsumura Y. The drug discovery by nanomedicine and its clinical experience. Jpn. J. Clin. Oncol. 2014, 44(6):515-525.
    • (2014) Jpn. J. Clin. Oncol. , vol.44 , Issue.6 , pp. 515-525
    • Matsumura, Y.1
  • 59
    • 33847720312 scopus 로고    scopus 로고
    • In vivo imaging of siRNA delivery and silencing in tumors
    • Medarova Z., et al. In vivo imaging of siRNA delivery and silencing in tumors. Nat. Med. 2007, 13(3):372-377.
    • (2007) Nat. Med. , vol.13 , Issue.3 , pp. 372-377
    • Medarova, Z.1
  • 60
    • 85059774987 scopus 로고    scopus 로고
    • Magnetic nanoparticle drug delivery systems for targeting tumor
    • Mody V.V., et al. Magnetic nanoparticle drug delivery systems for targeting tumor. Appl. Nanosci. 2014, 4(4):385-392.
    • (2014) Appl. Nanosci. , vol.4 , Issue.4 , pp. 385-392
    • Mody, V.V.1
  • 61
    • 39649104546 scopus 로고    scopus 로고
    • Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice
    • Murata N., et al. Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice. J. Control. Release 2008, 126(3):246-254.
    • (2008) J. Control. Release , vol.126 , Issue.3 , pp. 246-254
    • Murata, N.1
  • 62
    • 52449091099 scopus 로고    scopus 로고
    • Designing phase 0 cancer clinical trials
    • Murgo A.J., et al. Designing phase 0 cancer clinical trials. Clin. Cancer Res. 2008, 14(12):3675-3682.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.12 , pp. 3675-3682
    • Murgo, A.J.1
  • 63
    • 84928128382 scopus 로고    scopus 로고
    • Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures
    • Murugan K., et al. Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures. Int. J. Nanomed. 2015, 10:2191-2206.
    • (2015) Int. J. Nanomed. , vol.10 , pp. 2191-2206
    • Murugan, K.1
  • 64
    • 84902529384 scopus 로고    scopus 로고
    • Nanotheranostics-application and further development of nanomedicine strategies for advanced theranostics
    • Muthu M.S., et al. Nanotheranostics-application and further development of nanomedicine strategies for advanced theranostics. Theranostics 2014, 4(6):660-677.
    • (2014) Theranostics , vol.4 , Issue.6 , pp. 660-677
    • Muthu, M.S.1
  • 65
    • 63649092083 scopus 로고    scopus 로고
    • Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles
    • Nam H.Y., et al. Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J. Control. Release 2009, 135(3):259-267.
    • (2009) J. Control. Release , vol.135 , Issue.3 , pp. 259-267
    • Nam, H.Y.1
  • 66
    • 84899699311 scopus 로고    scopus 로고
    • Analysis of growth factor signaling in genetically diverse breast cancer lines
    • Niepel M., et al. Analysis of growth factor signaling in genetically diverse breast cancer lines. BMC Biol. 2014, 12:20.
    • (2014) BMC Biol. , vol.12 , pp. 20
    • Niepel, M.1
  • 67
    • 67649295505 scopus 로고    scopus 로고
    • SiRNA delivery systems for cancer treatment
    • Oh Y.-K., Park T.G. siRNA delivery systems for cancer treatment. Adv. Drug Deliv. Rev. 2009, 61(10):850-862.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , Issue.10 , pp. 850-862
    • Oh, Y.-K.1    Park, T.G.2
  • 68
    • 84900401078 scopus 로고    scopus 로고
    • Endocytosis and exocytosis of nanoparticles in mammalian cells
    • Oh N., Park J.-H. Endocytosis and exocytosis of nanoparticles in mammalian cells. Int. J. Nanomed. 2014, 9(Suppl. 1):51-63.
    • (2014) Int. J. Nanomed. , vol.9 , pp. 51-63
    • Oh, N.1    Park, J.-H.2
  • 69
    • 33645167401 scopus 로고    scopus 로고
    • Prospects of RNA interference therapy for cancer
    • Pai S.I., et al. Prospects of RNA interference therapy for cancer. Gene Ther. 2005, 13(6):464-477.
    • (2005) Gene Ther. , vol.13 , Issue.6 , pp. 464-477
    • Pai, S.I.1
  • 70
    • 84944450592 scopus 로고    scopus 로고
    • Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium E. coli
    • Pal S., Tak Y.K., Song J.M. Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium E. coli. Appl. Environ. Microbiol. 2007, 73(6):1712-1720.
    • (2007) Appl. Environ. Microbiol. , vol.73 , Issue.6 , pp. 1712-1720
    • Pal, S.1    Tak, Y.K.2    Song, J.M.3
  • 72
    • 0037026269 scopus 로고    scopus 로고
    • Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles
    • Prabha S., et al. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int. J. Pharm. 2002, 244(1-2):105-115.
    • (2002) Int. J. Pharm. , vol.244 , Issue.1-2 , pp. 105-115
    • Prabha, S.1
  • 73
    • 59849103061 scopus 로고    scopus 로고
    • Drug delivery of siRNA therapeutics: potentials and limits of nanosystems
    • Reischl D., Zimmer A. Drug delivery of siRNA therapeutics: potentials and limits of nanosystems. Nanomedicine 2009, 5(1):8-20.
    • (2009) Nanomedicine , vol.5 , Issue.1 , pp. 8-20
    • Reischl, D.1    Zimmer, A.2
  • 74
    • 84879074792 scopus 로고    scopus 로고
    • A review of the current status of siRNA nanomedicines in the treatment of cancer
    • Resnier P., et al. A review of the current status of siRNA nanomedicines in the treatment of cancer. Biomaterials 2013, 34(27):6429-6443.
    • (2013) Biomaterials , vol.34 , Issue.27 , pp. 6429-6443
    • Resnier, P.1
  • 75
    • 0031718447 scopus 로고    scopus 로고
    • Host microvasculature influence on tumor vascular morphology and endothelial gene expression
    • Roberts W.G., et al. Host microvasculature influence on tumor vascular morphology and endothelial gene expression. Am. J. Pathol. 1998, 153(4):1239-1248.
    • (1998) Am. J. Pathol. , vol.153 , Issue.4 , pp. 1239-1248
    • Roberts, W.G.1
  • 76
    • 27244436755 scopus 로고    scopus 로고
    • Design issues of randomized phase II trials and a proposal for phase II screening trials
    • Rubinstein L.V., et al. Design issues of randomized phase II trials and a proposal for phase II screening trials. J. Clin. Oncol. 2005, 23(28):7199-7206.
    • (2005) J. Clin. Oncol. , vol.23 , Issue.28 , pp. 7199-7206
    • Rubinstein, L.V.1
  • 77
    • 84906787631 scopus 로고    scopus 로고
    • Theranostic nanoparticles for future personalized medicine
    • Ryu J.H., et al. Theranostic nanoparticles for future personalized medicine. J. Control. Release 2014, 190:477-484.
    • (2014) J. Control. Release , vol.190 , pp. 477-484
    • Ryu, J.H.1
  • 78
    • 84864138481 scopus 로고    scopus 로고
    • Hybrid nanoparticles for detection and treatment of cancer
    • Sailor M.J., Park J.H. Hybrid nanoparticles for detection and treatment of cancer. Adv. Mater. 2012, 24(28):3779-3802.
    • (2012) Adv. Mater. , vol.24 , Issue.28 , pp. 3779-3802
    • Sailor, M.J.1    Park, J.H.2
  • 79
    • 84929711904 scopus 로고    scopus 로고
    • Protamine-oligonucleotide-nanoparticles: recent advances in drug delivery and drug targeting
    • Scheicher B., Schachner-Nedherer A.L., Zimmer A. Protamine-oligonucleotide-nanoparticles: recent advances in drug delivery and drug targeting. Eur. J. Pharm. Sci. 2015, 0.
    • (2015) Eur. J. Pharm. Sci.
    • Scheicher, B.1    Schachner-Nedherer, A.L.2    Zimmer, A.3
  • 80
    • 33746556993 scopus 로고    scopus 로고
    • A brief history of RNAi: the silence of the genes
    • Sen G.L., Blau H.M. A brief history of RNAi: the silence of the genes. FASEB J. 2006, 20(9):1293-1299.
    • (2006) FASEB J. , vol.20 , Issue.9 , pp. 1293-1299
    • Sen, G.L.1    Blau, H.M.2
  • 81
    • 0036643599 scopus 로고    scopus 로고
    • Thermal stability of unsupported gold nanoparticle: a molecular dynamics study
    • Shim J.-H., Lee B.-J., Cho Y.W. Thermal stability of unsupported gold nanoparticle: a molecular dynamics study. Surf. Sci. 2002, 512(3):262-268.
    • (2002) Surf. Sci. , vol.512 , Issue.3 , pp. 262-268
    • Shim, J.-H.1    Lee, B.-J.2    Cho, Y.W.3
  • 82
    • 84939977109 scopus 로고    scopus 로고
    • The role of BIM-EL and BCL2-α on the efficacy of erlotinib and gefitinib in lung cancer
    • Simasi J., et al. The role of BIM-EL and BCL2-α on the efficacy of erlotinib and gefitinib in lung cancer. Respir. Physiol. Neurobiol. 2015, 209(0):64-68.
    • (2015) Respir. Physiol. Neurobiol. , vol.209 , pp. 64-68
    • Simasi, J.1
  • 83
    • 80052140404 scopus 로고    scopus 로고
    • Polymers in small-interfering RNA delivery
    • Singha K., Namgung R., Kim W.J. Polymers in small-interfering RNA delivery. Nucleic Ther. 2011, 21(3):133-147.
    • (2011) Nucleic Ther. , vol.21 , Issue.3 , pp. 133-147
    • Singha, K.1    Namgung, R.2    Kim, W.J.3
  • 84
    • 84884345827 scopus 로고    scopus 로고
    • Recommendations for the design of Phase 3 pharmaceutical trials that are more informative for patients, clinicians, and payers
    • Sonnad S.S., et al. Recommendations for the design of Phase 3 pharmaceutical trials that are more informative for patients, clinicians, and payers. Contemp. Clin. Trials 2013, 36(2):356-361.
    • (2013) Contemp. Clin. Trials , vol.36 , Issue.2 , pp. 356-361
    • Sonnad, S.S.1
  • 85
    • 84877120847 scopus 로고    scopus 로고
    • First-in-humans trial of an rna interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
    • Tabernero J., et al. First-in-humans trial of an rna interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 2013, 3(4):406-417.
    • (2013) Cancer Discov. , vol.3 , Issue.4 , pp. 406-417
    • Tabernero, J.1
  • 86
    • 33845975678 scopus 로고    scopus 로고
    • Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference
    • Tan W.B., Jiang S., Zhang Y. Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference. Biomaterials 2007, 28(8):1565-1571.
    • (2007) Biomaterials , vol.28 , Issue.8 , pp. 1565-1571
    • Tan, W.B.1    Jiang, S.2    Zhang, Y.3
  • 87
    • 68149173128 scopus 로고    scopus 로고
    • In quest of a systematic framework for unifying and defining nanoscience
    • Tomalia D. In quest of a systematic framework for unifying and defining nanoscience. J. Nanopart. Res. 2009, 11(6):1251-1310.
    • (2009) J. Nanopart. Res. , vol.11 , Issue.6 , pp. 1251-1310
    • Tomalia, D.1
  • 88
    • 84896504632 scopus 로고    scopus 로고
    • Shaping cancer nanomedicine: The effect of particle shape on the in vivo journey of nanoparticles
    • Toy R., et al. Shaping cancer nanomedicine: The effect of particle shape on the in vivo journey of nanoparticles. Nanomedicine (London, England) 2014, 9(1):121-134.
    • (2014) Nanomedicine (London, England) , vol.9 , Issue.1 , pp. 121-134
    • Toy, R.1
  • 89
    • 84957665357 scopus 로고    scopus 로고
    • [cited 2014 18 March]
    • U.S. National Institutes of Health. TKM 080301 for Primary or Secondary Liver Cancer. 2014 [cited 2014 18 March]; Available from:. http://www.clinicaltrials.gov/ct2/show/NCT01437007%3Fterm=siRNA+cancer&rank=6.
    • (2014) TKM 080301 for Primary or Secondary Liver Cancer
  • 90
    • 84878630603 scopus 로고    scopus 로고
    • RNAi therapeutics and applications of MicroRNAs in cancer treatment
    • Uchino K., Ochiya T., Takeshita F. RNAi therapeutics and applications of MicroRNAs in cancer treatment. Jpn. J. Clin. Oncol. 2013, 43(6):596-607.
    • (2013) Jpn. J. Clin. Oncol. , vol.43 , Issue.6 , pp. 596-607
    • Uchino, K.1    Ochiya, T.2    Takeshita, F.3
  • 91
    • 78649659237 scopus 로고    scopus 로고
    • Delivery of siRNA therapeutics: barriers and carriers
    • Wang J., et al. Delivery of siRNA therapeutics: barriers and carriers. AAPS J. 2010, 12(4):492-503.
    • (2010) AAPS J. , vol.12 , Issue.4 , pp. 492-503
    • Wang, J.1
  • 93
    • 84872477242 scopus 로고    scopus 로고
    • The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems
    • Wu M., et al. The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems. J. Theor. Biol. 2013, 320(0):131-151.
    • (2013) J. Theor. Biol. , vol.320 , pp. 131-151
    • Wu, M.1
  • 94
    • 84904544984 scopus 로고    scopus 로고
    • Non-viral vectors for gene-based therapy
    • Yin H., et al. Non-viral vectors for gene-based therapy. Nat. Rev. Genet. 2014, 15(8):541-555.
    • (2014) Nat. Rev. Genet. , vol.15 , Issue.8 , pp. 541-555
    • Yin, H.1
  • 95
    • 0345415567 scopus 로고    scopus 로고
    • Molecular dynamics simulations, thermodynamic analysis, and experimental study of phase stability of zinc sulfide nanoparticles
    • Zhang H., et al. Molecular dynamics simulations, thermodynamic analysis, and experimental study of phase stability of zinc sulfide nanoparticles. J. Phys. Chem. B 2003, 107(47):13051-13060.
    • (2003) J. Phys. Chem. B , vol.107 , Issue.47 , pp. 13051-13060
    • Zhang, H.1
  • 96
    • 84891718629 scopus 로고    scopus 로고
    • Chemical modification of inorganic nanostructures for targeted and controlled drug delivery in cancer treatment
    • Zhang L., Li Y., Jimmy C.Y. Chemical modification of inorganic nanostructures for targeted and controlled drug delivery in cancer treatment. J. Mater. Chem. B 2014, 2(5):452-470.
    • (2014) J. Mater. Chem. B , vol.2 , Issue.5 , pp. 452-470
    • Zhang, L.1    Li, Y.2    Jimmy, C.Y.3
  • 97
    • 84906788645 scopus 로고    scopus 로고
    • Non-viral nanocarriers for siRNA delivery in breast cancer
    • Zhang J., Li X., Huang L. Non-viral nanocarriers for siRNA delivery in breast cancer. J. Control. Release 2014, 190(0):440-450.
    • (2014) J. Control. Release , vol.190 , pp. 440-450
    • Zhang, J.1    Li, X.2    Huang, L.3
  • 98
    • 84955387882 scopus 로고    scopus 로고
    • Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy
    • Springer, New York, M. Sioud (Ed.)
    • Zins K., et al. Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy. RNA Interference 2015, 143-161. Springer, New York. M. Sioud (Ed.).
    • (2015) RNA Interference , pp. 143-161
    • Zins, K.1
  • 99
    • 84905670761 scopus 로고    scopus 로고
    • Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
    • Zuckerman J.E., et al. Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. Proc. Natl. Acad. Sci. U. S. A. 2014, 111(31):11449-11454.
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , Issue.31 , pp. 11449-11454
    • Zuckerman, J.E.1


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