-
1
-
-
42549157140
-
Endothelium in health and disease
-
Aird WC. Endothelium in health and disease. Pharmacol Rep. 2008;60:139-143.
-
(2008)
Pharmacol Rep.
, vol.60
, pp. 139-143
-
-
Aird, W.C.1
-
2
-
-
0032525207
-
Endothelial cells in physiology and in the pathophysiology of vascular disorders
-
Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stern DM. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood. 1998;91:3527-3561.
-
(1998)
Blood.
, vol.91
, pp. 3527-3561
-
-
Cines, D.B.1
Pollak, E.S.2
Buck, C.A.3
Loscalzo, J.4
Zimmerman, G.A.5
McEver, R.P.6
Pober, J.S.7
Wick, T.M.8
Konkle, B.A.9
Schwartz, B.S.10
Barnathan, E.S.11
McCrae, K.R.12
Hug, B.A.13
Schmidt, A.M.14
Stern, D.M.15
-
3
-
-
33644839612
-
Signaling mechanisms regulating endothelial permeability
-
Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev. 2006;86:279-367. doi: 10.1152/physrev. 00012.2005.
-
(2006)
Physiol Rev.
, vol.86
, pp. 279-367
-
-
Mehta, D.1
Malik, A.B.2
-
4
-
-
3042588831
-
Molecular regulation of vascular smooth muscle cell differentiation in development and disease
-
Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev. 2004;84:767-801. doi: 10.1152/physrev.00041.2003.
-
(2004)
Physiol Rev.
, vol.84
, pp. 767-801
-
-
Owens, G.K.1
Kumar, M.S.2
Wamhoff, B.R.3
-
5
-
-
0021795598
-
Intimal proliferation of smooth muscle cells as an explanation for recurrent coronary artery stenosis after percutaneous transluminal coronary angioplasty
-
Austin GE, Ratliff NB, Hollman J, Tabei S, Phillips DF. Intimal proliferation of smooth muscle cells as an explanation for recurrent coronary artery stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1985;6:369-375.
-
(1985)
J Am Coll Cardiol.
, vol.6
, pp. 369-375
-
-
Austin, G.E.1
Ratliff, N.B.2
Hollman, J.3
Tabei, S.4
Phillips, D.F.5
-
6
-
-
0026612517
-
The restenosis paradigm revisited: An alternative proposal for cellular mechanisms
-
Schwartz RS, Holmes DR Jr, Topol EJ. The restenosis paradigm revisited: an alternative proposal for cellular mechanisms. J Am Coll Cardiol. 1992;20:1284-1293.
-
(1992)
J Am Coll Cardiol.
, vol.20
, pp. 1284-1293
-
-
Schwartz, R.S.1
Holmes, D.R.2
Topol, E.J.3
-
7
-
-
0027363053
-
Response of human coronary arteries to serotonin after injury by coronary angioplasty
-
Mc Fadden EP, Bauters C, Lablanche JM, Quandalle P, Leroy F, Bertrand ME. Response of human coronary arteries to serotonin after injury by coronary angioplasty. Circulation. 1993;88(pt 1):2076-2085.
-
(1993)
Circulation.
, vol.88
, pp. 2076-2085
-
-
Mc Fadden, E.P.1
Bauters, C.2
Lablanche, J.M.3
Quandalle, P.4
Leroy, F.5
Bertrand, M.E.6
-
8
-
-
0033552883
-
Atherosclerosis: An infammatory disease
-
Ross R. Atherosclerosis: an infammatory disease. N Engl J Med. 1999;340:115-126. doi: 10.1056/NEJM199901143400207.
-
(1999)
N Engl J Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
10
-
-
0034604129
-
The acute respiratory distress syndrome
-
Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med. 2000;342:1334-1349. doi: 10.1056/NEJM200005043421806.
-
(2000)
N Engl J Med.
, vol.342
, pp. 1334-1349
-
-
Ware, L.B.1
Matthay, M.A.2
-
11
-
-
33748302966
-
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury
-
Zhao YY, Gao XP, Zhao YD, Mirza MK, Frey RS, Kalinichenko VV, Wang IC, Costa RH, Malik AB. Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. J Clin Invest. 2006;116:2333-2343. doi: 10.1172/JCI27154.
-
(2006)
J Clin Invest.
, vol.116
, pp. 2333-2343
-
-
Zhao, Y.Y.1
Gao, X.P.2
Zhao, Y.D.3
Mirza, M.K.4
Frey, R.S.5
Kalinichenko, V.V.6
Wang, I.C.7
Costa, R.H.8
Malik, A.B.9
-
12
-
-
33748312129
-
Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury
-
Minamino T, Komuro I. Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury. J Clin Invest. 2006;116:2316-2319. doi: 10.1172/JCI29637.
-
(2006)
J Clin Invest.
, vol.116
, pp. 2316-2319
-
-
Minamino, T.1
Komuro, I.2
-
13
-
-
77951836880
-
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and infuenza
-
23ra19
-
London NR, Zhu W, Bozza FA, Smith MC, Greif DM, Sorensen LK, Chen L, Kaminoh Y, Chan AC, Passi SF, Day CW, Barnard DL, Zimmerman GA, Krasnow MA, Li DY. Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and infuenza. Sci Transl Med. 2010;2:23ra19. doi: 10.1126/scitranslmed.3000678.
-
(2010)
Sci Transl Med.
, vol.2
-
-
London, N.R.1
Zhu, W.2
Bozza, F.A.3
Smith, M.C.4
Greif, D.M.5
Sorensen, L.K.6
Chen, L.7
Kaminoh, Y.8
Chan, A.C.9
Passi, S.F.10
Day, C.W.11
Barnard, D.L.12
Zimmerman, G.A.13
Krasnow, M.A.14
Li, D.Y.15
-
14
-
-
77956635947
-
Sepsis and endothelial permeability
-
Lee WL, Slutsky AS. Sepsis and endothelial permeability. N Engl J Med. 2010;363:689-691. doi: 10.1056/NEJMcibr1007320.
-
(2010)
N Engl J Med.
, vol.363
, pp. 689-691
-
-
Lee, W.L.1
Slutsky, A.S.2
-
15
-
-
77955395384
-
FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression
-
Mirza MK, Sun Y, Zhao YD, Potula HH, Frey RS, Vogel SM, Malik AB, Zhao YY. FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression. J Exp Med. 2010;207:1675-1685. doi: 10.1084/jem.20091857.
-
(2010)
J Exp Med.
, vol.207
, pp. 1675-1685
-
-
Mirza, M.K.1
Sun, Y.2
Zhao, Y.D.3
Potula, H.H.4
Frey, R.S.5
Vogel, S.M.6
Malik, A.B.7
Zhao, Y.Y.8
-
16
-
-
1842632667
-
Endothelial cell-cell junctions: Happy together
-
Dejana E. Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol. 2004;5:261-270. doi: 10.1038/nrm1357.
-
(2004)
Nat Rev Mol Cell Biol.
, vol.5
, pp. 261-270
-
-
Dejana, E.1
-
18
-
-
0342614209
-
Unifed nomenclature for the winged helix/forkhead transcription factors
-
Kaestner KH, Knochel W, Martinez DE. Unifed nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 2000;14:142-146.
-
(2000)
Genes Dev.
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
19
-
-
13944281061
-
FoxM1 dances with mitosis
-
Costa RH. FoxM1 dances with mitosis. Nat Cell Biol. 2005;7:108-110. doi: 10.1038/ncb0205-108.
-
(2005)
Nat Cell Biol.
, vol.7
, pp. 108-110
-
-
Costa, R.H.1
-
20
-
-
0141733085
-
Ubiquitous expression of the forkhead box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury
-
Kalinichenko VV, Gusarova GA, Tan Y, Wang IC, Major ML, Wang X, Yoder HM, Costa RH, Costal RH. Ubiquitous expression of the forkhead box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury. J Biol Chem. 2003;278:37888-37894. doi: 10.1074/jbc.M305555200.
-
(2003)
J Biol Chem.
, vol.278
, pp. 37888-37894
-
-
Kalinichenko, V.V.1
Gusarova, G.A.2
Tan, Y.3
Wang, I.C.4
Major, M.L.5
Wang, X.6
Yoder, H.M.7
Costa, R.H.8
Costal, R.H.9
-
21
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
Laoukili J, Kooistra MR, Brás A, Kauw J, Kerkhoven RM, Morrison A, Clevers H, Medema RH. FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol. 2005;7:126-136. doi: 10.1038/ncb1217.
-
(2005)
Nat Cell Biol.
, vol.7
, pp. 126-136
-
-
Laoukili, J.1
Kooistra, M.R.2
Brás, A.3
Kauw, J.4
Kerkhoven, R.M.5
Morrison, A.6
Clevers, H.7
Medema, R.H.8
-
22
-
-
0031020158
-
Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
-
Ye H, Kelly TF, Samadani U, Lim L, Rubio S, Overdier DG, Roebuck KA, Costa RH. Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol Cell Biol. 1997;17:1626-1641.
-
(1997)
Mol Cell Biol.
, vol.17
, pp. 1626-1641
-
-
Ye, H.1
Kelly, T.F.2
Samadani, U.3
Lim, L.4
Rubio, S.5
Overdier, D.G.6
Roebuck, K.A.7
Costa, R.H.8
-
23
-
-
0021828496
-
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
-
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature. 1985;315:239-242.
-
(1985)
Nature.
, vol.315
, pp. 239-242
-
-
Whitman, M.1
Kaplan, D.R.2
Schaffhausen, B.3
Cantley, L.4
Roberts, T.M.5
-
24
-
-
0032929762
-
Signalling through phos-phoinositide 3-kinases: The lipids take centre stage
-
Leevers SJ, Vanhaesebroeck B, Waterfeld MD. Signalling through phos-phoinositide 3-kinases: the lipids take centre stage. Curr Opin Cell Biol. 1999;11:219-225.
-
(1999)
Curr Opin Cell Biol.
, vol.11
, pp. 219-225
-
-
Leevers, S.J.1
Vanhaesebroeck, B.2
Waterfeld, M.D.3
-
25
-
-
0030887632
-
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
Stephens LR, Eguinoa A, Erdjument-Bromage H, Lui M, Cooke F, Coadwell J, Smrcka AS, Thelen M, Cadwallader K, Tempst P, Hawkins PT. The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Cell. 1997;89:105-114.
-
(1997)
Cell.
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
Lui, M.4
Cooke, F.5
Coadwell, J.6
Smrcka, A.S.7
Thelen, M.8
Cadwallader, K.9
Tempst, P.10
Hawkins, P.T.11
-
26
-
-
46149106818
-
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma
-
Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, Meek S, Smith AJ, Okkenhaug K, Vanhaesebroeck B. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci USA. 2008;105:8292-8297. doi: 10.1073/pnas.0707761105.
-
(2008)
Proc Natl Acad Sci USA.
, vol.105
, pp. 8292-8297
-
-
Guillermet-Guibert, J.1
Bjorklof, K.2
Salpekar, A.3
Gonella, C.4
Ramadani, F.5
Bilancio, A.6
Meek, S.7
Smith, A.J.8
Okkenhaug, K.9
Vanhaesebroeck, B.10
-
27
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in infammation
-
Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, Wymann MP. Central role for G protein-coupled phosphoinositide 3-kinase gamma in infammation. Science. 2000;287:1049-1053.
-
(2000)
Science.
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
Sozzani, S.7
Mantovani, A.8
Altruda, F.9
Wymann, M.P.10
-
28
-
-
33845896298
-
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis
-
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat Cell Biol. 2007;9:86-91. doi: 10.1038/ncb1517.
-
(2007)
Nat Cell Biol.
, vol.9
, pp. 86-91
-
-
Ferguson, G.J.1
Milne, L.2
Kulkarni, S.3
Sasaki, T.4
Walker, S.5
Andrews, S.6
Crabbe, T.7
Finan, P.8
Jones, G.9
Jackson, S.10
Camps, M.11
Rommel, C.12
Wymann, M.13
Hirsch, E.14
Hawkins, P.15
Stephens, L.16
-
29
-
-
27944483014
-
Role of phos-phatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. Coli sepsis
-
Ong E, Gao XP, Predescu D, Broman M, Malik AB. Role of phos-phatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis. Am J Physiol Lung Cell Mol Physiol. 2005;289:L1094-L1103. doi: 10.1152/ajplung.00179.2005.
-
(2005)
Am J Physiol Lung Cell Mol Physiol.
, vol.289
, pp. L1094-L1103
-
-
Ong, E.1
Gao, X.P.2
Predescu, D.3
Broman, M.4
Malik, A.B.5
-
30
-
-
0035575706
-
Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury
-
Yum HK, Arcaroli J, Kupfner J, Shenkar R, Penninger JM, Sasaki T, Yang KY, Park JS, Abraham E. Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. J Immunol. 2001;167:6601-6608.
-
(2001)
J Immunol.
, vol.167
, pp. 6601-6608
-
-
Yum, H.K.1
Arcaroli, J.2
Kupfner, J.3
Shenkar, R.4
Penninger, J.M.5
Sasaki, T.6
Yang, K.Y.7
Park, J.S.8
Abraham, E.9
-
31
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development T cell activation and neutrophil migration
-
Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi PS, Suzuki A, Penninger JM. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science. 2000;287:1040-1046.
-
(2000)
Science.
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-Dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
Wakeham, A.7
Itie, A.8
Bouchard, D.9
Kozieradzki, I.10
Joza, N.11
Mak, T.W.12
Ohashi, P.S.13
Suzuki, A.14
Penninger, J.M.15
-
32
-
-
39649102180
-
Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway
-
Hers I. Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway. Blood. 2007;110:4243-4252. doi: 10.1182/blood-2006-10-050633.
-
(2007)
Blood.
, vol.110
, pp. 4243-4252
-
-
Hers, I.1
-
33
-
-
24744435115
-
Blockade of PI3Kgamma suppresses joint infammation and damage in mouse models of rheumatoid arthritis
-
Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Blockade of PI3Kgamma suppresses joint infammation and damage in mouse models of rheumatoid arthritis. Nat Med. 2005;11:936-943. doi: 10.1038/nm1284.
-
(2005)
Nat Med.
, vol.11
, pp. 936-943
-
-
Camps, M.1
Rückle, T.2
Ji, H.3
Ardissone, V.4
Rintelen, F.5
Shaw, J.6
Ferrandi, C.7
Chabert, C.8
Gillieron, C.9
Françon, B.10
Martin, T.11
Gretener, D.12
Perrin, D.13
Leroy, D.14
Vitte, P.A.15
Hirsch, E.16
Wymann, M.P.17
Cirillo, R.18
Schwarz, M.K.19
Rommel, C.20
more..
-
34
-
-
84869835597
-
Transgenic expression of FoxM1 promotes endothelial repair following lung injury induced by polymicrobial sepsis in mice
-
Huang X, Zhao YY Transgenic expression of FoxM1 promotes endothelial repair following lung injury induced by polymicrobial sepsis in mice. PLoS One. 2012;7:e50094. doi: 10.1371/journal.pone.0050094.
-
(2012)
PLoS One.
, vol.7
, pp. e50094
-
-
Huang, X.1
Zhao, Y.Y.2
-
35
-
-
18344364910
-
The human VE-cadherin promoter is subjected to organ-specifc regulation and is activated in tumour angiogenesis
-
Prandini MH, Dreher I, Bouillot S, Benkerri S, Moll T, Huber P. The human VE-cadherin promoter is subjected to organ-specifc regulation and is activated in tumour angiogenesis. Oncogene. 2005;24:2992-3001. doi: 10.1038/sj.onc.1208483.
-
(2005)
Oncogene.
, vol.24
, pp. 2992-3001
-
-
Prandini, M.H.1
Dreher, I.2
Bouillot, S.3
Benkerri, S.4
Moll, T.5
Huber, P.6
-
36
-
-
0036841093
-
Fas and fas ligand are up-regulated in pulmonary edema fuid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome
-
Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB. Fas and fas ligand are up-regulated in pulmonary edema fuid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol. 2002;161:1783-1796. doi: 10.1016/S0002-9440(10)64455-0.
-
(2002)
Am J Pathol.
, vol.161
, pp. 1783-1796
-
-
Albertine, K.H.1
Soulier, M.F.2
Wang, Z.3
Ishizaka, A.4
Hashimoto, S.5
Zimmerman, G.A.6
Matthay, M.A.7
Ware, L.B.8
-
37
-
-
77958127193
-
Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: Improvement of fasting glycemia in diabetic db/db mice
-
Nagashima T, Shigematsu N, Maruki R, Urano Y, Tanaka H, Shimaya A, Shimokawa T, Shibasaki M. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol Pharmacol. 2010;78:961-970. doi: 10.1124/mol.110.065714.
-
(2010)
Mol Pharmacol.
, vol.78
, pp. 961-970
-
-
Nagashima, T.1
Shigematsu, N.2
Maruki, R.3
Urano, Y.4
Tanaka, H.5
Shimaya, A.6
Shimokawa, T.7
Shibasaki, M.8
-
38
-
-
17844365847
-
The psammaplysenes, specifc inhibitors of FOXO1a nuclear export
-
Schroeder FC, Kau TR, Silver PA, Clardy J. The psammaplysenes, specifc inhibitors of FOXO1a nuclear export. J Nat Prod. 2005;68:574-576. doi: 10.1021/np049624z.
-
(2005)
J Nat Prod.
, vol.68
, pp. 574-576
-
-
Schroeder, F.C.1
Kau, T.R.2
Silver, P.A.3
Clardy, J.4
-
39
-
-
77953957570
-
EPS8 upregulates FOXM1 expression, enhancing cell growth and motility
-
Wang H, Teh MT, Ji Y, Patel V, Firouzabadian S, Patel AA, Gutkind JS, Yeudall WA. EPS8 upregulates FOXM1 expression, enhancing cell growth and motility. Carcinogenesis. 2010;31:1132-1141. doi: 10.1093/carcin/bgq058.
-
(2010)
Carcinogenesis.
, vol.31
, pp. 1132-1141
-
-
Wang, H.1
Teh, M.T.2
Ji, Y.3
Patel, V.4
Firouzabadian, S.5
Patel, A.A.6
Gutkind, J.S.7
Yeudall, W.A.8
-
40
-
-
84872186366
-
Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis
-
Tibolla G, Piñeiro R, Chiozzotto D, Mavrommati I, Wheeler AP, Norata GD, Catapano AL, Maffucci T, Falasca M. Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis. PLoS One. 2013;8:e53808. doi: 10.1371/journal.pone.0053808.
-
(2013)
PLoS One.
, vol.8
, pp. e53808
-
-
Tibolla, G.1
Piñeiro, R.2
Chiozzotto, D.3
Mavrommati, I.4
Wheeler, A.P.5
Norata, G.D.6
Catapano, A.L.7
Maffucci, T.8
Falasca, M.9
-
41
-
-
62849114529
-
Regulation of phosphoinositide 3-kinase expression in health and disease
-
Kok K, Geering B, Vanhaesebroeck B. Regulation of phosphoinositide 3-kinase expression in health and disease. Trends Biochem Sci. 2009;34:115-127. doi: 10.1016/j.tibs.2009.01.003.
-
(2009)
Trends Biochem Sci.
, vol.34
, pp. 115-127
-
-
Kok, K.1
Geering, B.2
Vanhaesebroeck, B.3
-
42
-
-
33750525089
-
PI3Kgamma inhibition: Towards an "aspirin of the 21st century"?
-
Rückle T, Schwarz MK, Rommel C. PI3Kgamma inhibition: towards an "aspirin of the 21st century"? Nat Rev Drug Discov. 2006;5:903-918. doi: 10.1038/nrd2145.
-
(2006)
Nat Rev Drug Discov.
, vol.5
, pp. 903-918
-
-
Rückle, T.1
Schwarz, M.K.2
Rommel, C.3
-
44
-
-
0030755027
-
Transendothelial neutrophil migration: Role of neutrophil-derived proteases and relationship to transendothelial protein movement
-
Cepinskas G, Noseworthy R, Kvietys PR. Transendothelial neutrophil migration: role of neutrophil-derived proteases and relationship to transendothelial protein movement. Circ Res. 1997;81:618-626.
-
(1997)
Circ Res.
, vol.81
, pp. 618-626
-
-
Cepinskas, G.1
Noseworthy, R.2
Kvietys, P.R.3
-
45
-
-
77951676945
-
The regulation of leucocyte transendothelial migration by endothelial signalling events
-
Fernandez-Borja M, van Buul JD, Hordijk PL. The regulation of leucocyte transendothelial migration by endothelial signalling events. Cardiovasc Res. 2010;86:202-210. doi: 10.1093/cvr/cvq003.
-
(2010)
Cardiovasc Res.
, vol.86
, pp. 202-210
-
-
Fernandez-Borja, M.1
Van Buul, J.D.2
Hordijk, P.L.3
-
46
-
-
84863575573
-
PI3K-y inhibition ameliorates acute lung injury through regulation of IKBa/NF-KB pathway and innate immune responses
-
Kim DI, Kim SR, Kim HJ, Lee SJ, Lee HB, Park SJ, Im MJ, Lee YC. PI3K-y inhibition ameliorates acute lung injury through regulation of IKBa/NF-KB pathway and innate immune responses. J Clin Immunol. 2012;32:340-351. doi: 10.1007/s10875-011-9628-1.
-
(2012)
J Clin Immunol.
, vol.32
, pp. 340-351
-
-
Kim, D.I.1
Kim, S.R.2
Kim, H.J.3
Lee, S.J.4
Lee, H.B.5
Park, S.J.6
Im, M.J.7
Lee, Y.C.8
-
47
-
-
0346103719
-
Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
-
Williams DL, Li C, Ha T, Ozment-Skelton T, Kalbfeisch JH, Preiszner J, Brooks L, Breuel K, Schweitzer JB. Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol. 2004;172:449-456.
-
(2004)
J Immunol.
, vol.172
, pp. 449-456
-
-
Williams, D.L.1
Li, C.2
Ha, T.3
Ozment-Skelton, T.4
Kalbfeisch, J.H.5
Preiszner, J.6
Brooks, L.7
Breuel, K.8
Schweitzer, J.B.9
-
48
-
-
34247643153
-
The phosphatidylinositol 3-kinase signaling pathway exerts protective effects during sepsis by controlling C5a-mediated activation of innate immune functions
-
Wrann CD, Tabriz NA, Barkhausen T, Klos A, van Griensven M, Pape HC, Kendoff DO, Guo R, Ward PA, Krettek C, Riedemann NC. The phosphatidylinositol 3-kinase signaling pathway exerts protective effects during sepsis by controlling C5a-mediated activation of innate immune functions. J Immunol. 2007;178:5940-5948.
-
(2007)
J Immunol.
, vol.178
, pp. 5940-5948
-
-
Wrann, C.D.1
Tabriz, N.A.2
Barkhausen, T.3
Klos, A.4
Van Griensven, M.5
Pape, H.C.6
Kendoff, D.O.7
Guo, R.8
Ward, P.A.9
Krettek, C.10
Riedemann, N.C.11
-
49
-
-
34247607711
-
Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection
-
Maus UA, Backi M, Winter C, Srivastava M, Schwarz MK, Rückle T, Paton JC, Briles D, Mack M, Welte T, Maus R, Bohle RM, Seeger W, Rommel C, Hirsch E, Lohmeyer J, Preissner KT. Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection. Am J Respir Crit Care Med. 2007;175:958-966. doi: 10.1164/rccm.200610-1533OC.
-
(2007)
Am J Respir Crit Care Med.
, vol.175
, pp. 958-966
-
-
Maus, U.A.1
Backi, M.2
Winter, C.3
Srivastava, M.4
Schwarz, M.K.5
Rückle, T.6
Paton, J.C.7
Briles, D.8
Mack, M.9
Welte, T.10
Maus, R.11
Bohle, R.M.12
Seeger, W.13
Rommel, C.14
Hirsch, E.15
Lohmeyer, J.16
Preissner, K.T.17
-
50
-
-
77957043487
-
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment
-
Martin EL, Souza DG, Fagundes CT, Amaral FA, Assenzio B, Puntorieri V, Del Sorbo L, Fanelli V, Bosco M, Delsedime L, Pinho JF, Lemos VS, Souto FO, Alves-Filho JC, Cunha FQ, Slutsky AS, Ruckle T, Hirsch E, Teixeira MM, Ranieri VM. Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment. Am J Respir Crit Care Med. 2010;182:762-773. doi: 10.1164/rccm.201001-0088OC.
-
(2010)
Am J Respir Crit Care Med.
, vol.182
, pp. 762-773
-
-
Martin, E.L.1
Souza, D.G.2
Fagundes, C.T.3
Amaral, F.A.4
Assenzio, B.5
Puntorieri, V.6
Del Sorbo, L.7
Fanelli, V.8
Bosco, M.9
Delsedime, L.10
Pinho, J.F.11
Lemos, V.S.12
Souto, F.O.13
Alves-Filho, J.C.14
Cunha, F.Q.15
Slutsky, A.S.16
Ruckle, T.17
Hirsch, E.18
Teixeira, M.M.19
Ranieri, V.M.20
more..
|