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Angewandte Chemie - International Edition

Volumn 55, Issue 4, 2016, Pages 1540-1543

Small Cause, Great Impact: Modification of the Guanidine Group in the RGD Motif Controls Integrin Subtype Selectivity

(4) Kapp, Tobias G a Fottner, Maximilian a Maltsev, Oleg V a Kessler, Horst a

a TECHNICAL UNIVERSITY OF MUNICH (Germany)

Author keywords

cilengitide; integrin ligands; peptide modifications; receptor subtype selectivity; RGD motif

Indexed keywords

ALKYLATION; BINDING ENERGY; CHEMICAL MODIFICATION; HYDROGEN BONDS;

BINDING AFFINITIES; CILENGITIDE; FUNCTIONALIZATIONS; HYDROGEN BOND DONORS; INTEGRIN LIGANDS; POSITIVE CHARGES; RGD MOTIF; SYNTHETIC LIGANDS;

LIGANDS;

ARGINYL-GLYCYL-ASPARTIC ACID; GUANIDINE; INTEGRIN; OLIGOPEPTIDE;

BINDING SITE; CHEMISTRY;

BINDING SITES; GUANIDINE; INTEGRINS; OLIGOPEPTIDES;

EID: 84957430389 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201508713 Document Type: Article

Times cited : (24)

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