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Volumn 18, Issue 17, 2010, Pages 6292-6304

NG-Acyl-argininamides as NPY Y1 receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity

(5) Weiss, Stefan a Keller, Max a Bernhardt, Günther a Buschauer, Armin a König, Burkhard a

a UNIVERSITY OF REGENSBURG (Germany)

Author keywords

Acyl guanidines; BIBP 3226; GPCR; NPY

Indexed keywords

1 ( 4 FLUOROPHENYL) 16 ( 4 HYDROXYBENZYLCARBAMOYL) 1,6,9,18 TETRAOXO 19,19 DIPHENYL 2,5,10,12,17 PENTAAZANONADECAN 11 IMINIUM 2,2,2 TRIFLUOROACETIC ACID; 4 ( 2,2 DIPHENYLACETAMIDO) 1 ( 4 HYDROXYPHENYL) 9 IMINIO 3,11,14 TRIOXO N ( 2 PROPIONAMIDOETHYL) 2,8,10,15 TETRAAZAHEPTADECAN 17 AMINIUM 2,2,2 TRIFLUOROACETIC ACID; ACETIC ACID DERIVATIVE; BUFFER; GUANIDINE; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR ANTAGONIST; NG ACYL ARGININAMIDE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BINDING AFFINITY; CROSS LINKING; DEACYLATION; DRUG ANTAGONISM; DRUG BINDING; DRUG STABILITY; DRUG TOLERANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; PROTEIN CLEAVAGE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ACYLATION; ARGININE; HUMANS; KINETICS; RECEPTORS, NEUROPEPTIDE Y; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 77955982811 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2010.07.028 Document Type: Article

Times cited : (29)

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