Controlling the cytokine storm in severe bacterial diarrhoea with an oral Toll-like receptor 4 antagonist

Immunology

Volumn 147, Issue 2, 2016, Pages 178-189

  Islam, Dilara ^a   Lombardini, Eric ^a   Ruamsap, Nattaya ^a   Imerbsin, Rawiwan ^a   Khantapura, Patchariya ^a   Teo, Ian ^b   Neesanant, Pimmnapar ^a   Gonwong, Siriphan ^a   Yongvanitchit, Kosol ^a   Swierczewski, Brett E ^a   Mason, Carl J ^a   Shaunak, Sunil ^b  

^a ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Bacterial diarrhoea; Cytokines; Inflammation; Toll like receptor 4

Indexed keywords

DENDRIMER; DENDRIMER GLUCOSAMINE; FIBRIN; GAMMA INTERFERON; GLUCOSAMINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; POLYMER; POLYPROPYLETHERIMINE; RECEPTOR BLOCKING AGENT; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ANTIDIARRHEAL AGENT; CYTOKINE; POLYPROPYLETHERIMINE DENDRIMER GLUCOSAMINE; TOLL LIKE RECEPTOR 4;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; COLON; CONTROLLED STUDY; CYTOKINE STORM; DIARRHEA; DISEASE SEVERITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HISTOPATHOLOGY; IMMUNITY; MALE; MESENTERY LYMPH NODE; MUCUS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SHIGELLA DYSENTERIAE; TREATMENT OUTCOME; VASCULITIS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; DYSENTERY, BACILLARY; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LYMPH NODE; METABOLISM; MICROBIOLOGY; NECROSIS; ORAL DRUG ADMINISTRATION; PATHOGENICITY; PATHOLOGY; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; TIME FACTOR;

ADMINISTRATION, ORAL; ANIMALS; ANTIDIARRHEALS; COLON; CYTOKINES; DENDRIMERS; DISEASE MODELS, ANIMAL; DYSENTERY, BACILLARY; FEMALE; GLUCOSAMINE; HOST-PATHOGEN INTERACTIONS; LYMPH NODES; MACACA MULATTA; MALE; NECROSIS; NEUTROPHIL INFILTRATION; SEVERITY OF ILLNESS INDEX; SHIGELLA DYSENTERIAE; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 84956677362     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12549     Document Type: Article

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