Quantitative RT-PCR profiling of the rabbit immune response: Assessment of acute shigella flexneri infection

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Schnupf, Pamela ^a   Sansonetti, Philippe J ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLOOXYGENASE 2; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 22; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; PRIMER DNA;

ACUTE DISEASE; ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; EXON; EXPERIMENTAL RABBIT; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HIGH THROUGHPUT SCREENING; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; INTESTINE MUCOSA; MORPHOLOGY; NONHUMAN; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHIGELLOSIS; UPREGULATION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; ILEUM; IMMUNITY; IMMUNOLOGY; MALE; METABOLISM; METHODOLOGY; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; RABBIT; SHIGELLA FLEXNERI; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS; PROTOZOA; SHIGELLA FLEXNERI;

ACUTE DISEASE; ANIMALS; DNA PRIMERS; DYSENTERY, BACILLARY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; ILEUM; IMMUNITY; IMMUNOHISTOCHEMISTRY; MALE; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHIGELLA FLEXNERI; VIRULENCE;

EID: 84861889726     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036446     Document Type: Article

References (51)

1. Kreuter KA, El-Abbadi N, Shbeeb A, Tseng L, Mahon SB, et al. (2008) Development of a rabbit pleural cancer model by using VX2 tumors. Comparative medicine 58: 287-293.
2. Kang SJ, Grossniklaus HE, (2011) Rabbit model of retinoblastoma. Journal of biomedicine & biotechnology 2011 394730.
3. Phinikaridou A, Hallock KJ, Qiao Y, Hamilton JA, (2009) A robust rabbit model of human atherosclerosis and atherothrombosis. Journal of lipid research 50: 787-797.
4. Woodruff-Pak DS, Agelan A, Del Valle L, (2007) A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels. Journal of Alzheimer's disease: JAD 11: 371-383.
5. Milhorn D, Hamilton T, Nelson M, McNutt P, (2010) Progression of ocular sulfur mustard injury: development of a model system. Annals of the New York Academy of Sciences 1194: 72-80.
6. Tendler M, Almeida MS, Pinto RM, Noronha D, Katz N, (1991) Schistosoma mansoni-New Zealand rabbit model: resistance induced by infection followed by active immunization with protective antigens. The Journal of parasitology 77: 138-141.
7. Lopez-Revilla R, Reyes JL, Enriquez-Rincon F, Basurto MA, (1992) Immediate deterioration of rabbit colon preparations by Entamoeba histolytica trophozoite lysates. Parasitology research 78: 260-262.
8. Christensen ND, (2005) Cottontail rabbit papillomavirus (CRPV) model system to test antiviral and immunotherapeutic strategies. Antiviral chemistry & chemotherapy 16: 355-362.
9. Pavan-Langston D, (1990) Herpes simplex virus ocular infections: current concepts of acute, latent and reactivated disease. Transactions of the American Ophthalmological Society 88: 727-796.
10. Conner ME, Estes MK, Graham DY, (1988) Rabbit model of rotavirus infection. Journal of virology 62: 1625-1633.
11. Chandra J, Long L, Ghannoum MA, Mukherjee PK, (2011) A rabbit model for evaluation of catheter-associated fungal biofilms. Virulence 2: 466-474.
12. Chakrabarti A, Jatana M, Sharma SC, (1997) Rabbit as an animal model of paranasal sinus mycoses. Journal of medical and veterinary mycology: bi-monthly publication of the International Society for Human and Animal Mycology 35: 295-297.
13. Manabe YC, Kesavan AK, Lopez-Molina J, Hatem CL, Brooks M, et al. (2008) The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome. Tuberculosis 88: 187-196.
14. Fong IW, Chiu B, Viira E, Fong MW, Jang D, et al. (1997) Rabbit model for Chlamydia pneumoniae infection. Journal of clinical microbiology 35: 48-52.
15. Foley DM, Gayek RJ, Skare JT, Wagar EA, Champion CI, et al. (1995) Rabbit model of Lyme borreliosis: erythema migrans, infection-derived immunity, and identification of Borrelia burgdorferi proteins associated with virulence and protective immunity. The Journal of clinical investigation 96: 965-975.
16. Spira WM, Sack RB, Froehlich JL, (1981) Simple adult rabbit model for Vibrio cholerae and enterotoxigenic Escherichia coli diarrhea. Infection and immunity 32: 739-747.
17. Hanes DE, Robl MG, Schneider CM, Burr DH, (2001) New Zealand white rabbit as a nonsurgical experimental model for Salmonella enterica gastroenteritis. Infection and immunity 69: 6523-6526.
18. Zaucha GM, Pitt LM, Estep J, Ivins BE, Friedlander AM, (1998) The pathology of experimental anthrax in rabbits exposed by inhalation and subcutaneous inoculation. Archives of pathology & laboratory medicine 122: 982-992.
19. Perdomo OJ, Cavaillon JM, Huerre M, Ohayon H, Gounon P, et al. (1994) Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis. The Journal of experimental medicine 180: 1307-1319.
20. Arikawa E, Sun Y, Wang J, Zhou Q, Ning B, et al. (2008) Cross-platform comparison of SYBR Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study. BMC genomics 9: 328.
21. Godornes C, Leader BT, Molini BJ, Centurion-Lara A, Lukehart SA, (2007) Quantitation of rabbit cytokine mRNA by real-time RT-PCR. Cytokine 38: 1-7.
22. Phalipon A, Sansonetti PJ, (2007) Shigella's ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival? Immunology and cell biology 85: 119-129.
23. Raqib R, Lindberg AA, Wretlind B, Bardhan PK, Andersson U, et al. (1995) Persistence of local cytokine production in shigellosis in acute and convalescent stages. Infection and immunity 63: 289-296.
24. Katakura S, Reinholt FP, Karnell A, Huan PT, Trach DD, et al. (1990) The pathology of Shigella flexneri infection in rhesus monkeys: an endoscopic and histopathological study of colonic lesions. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica 98: 313-319.
25. Schroeder GN, Hilbi H, (2008) Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clinical microbiology reviews 21: 134-156.
26. Raqib R, Wretlind B, Lindberg AA, Ljungdahl A, Andersson J, (1996) Pathogenesis and immune responses in shigellosis. Annals of the New York Academy of Sciences 797: 299-301.
27. Sansonetti PJ, Arondel J, Huerre M, Harada A, Matsushima K, (1999) Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis. Infection and immunity 67: 1471-1480.
28. Singer M, Sansonetti PJ, (2004) IL-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of Shigella-induced colitis. Journal of immunology 173: 4197-4206.
29. Raqib R, Ekberg C, Sharkar P, Bardhan PK, Zychlinsky A, et al. (2002) Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2. Infection and immunity 70: 3199-3207.
30. Islam D, Bandholtz L, Nilsson J, Wigzell H, Christensson B, et al. (2001) Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator. Nature medicine 7: 180-185.
31. Sperandio B, Regnault B, Guo J, Zhang Z, Stanley SL Jr, et al. (2008) Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression. The Journal of experimental medicine 205: 1121-1132.
32. Raqib R, Sarker P, Bergman P, Ara G, Lindh M, et al. (2006) Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic. Proceedings of the National Academy of Sciences of the United States of America 103: 9178-9183.
33. Islam D, Veress B, Bardhan PK, Lindberg AA, Christensson B, (1997) In situ characterization of inflammatory responses in the rectal mucosae of patients with shigellosis. Infection and immunity 65: 739-749.
34. Raqib R, Mia SM, Qadri F, Alam TI, Alam NH, et al. (2000) Innate immune responses in children and adults with Shigellosis. Infection and immunity 68: 3620-3629.
35. Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, et al. (2010) Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity. Journal of immunology 184: 2076-2085.
36. Cua DJ, Tato CM, (2010) Innate IL-17-producing cells: the sentinels of the immune system. Nature reviews Immunology 10: 479-489.
37. Sonnenberg GF, Fouser LA, Artis D, (2011) Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nature immunology 12: 383-390.
38. Spits H, Di Santo JP, (2011) The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nature immunology 12: 21-27.
39. Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, et al. (2009) Differential roles of interleukin-17A and-17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30: 108-119.
40. Iwakura Y, Ishigame H, Saijo S, Nakae S, (2011) Functional specialization of interleukin-17 family members. Immunity 34: 149-162.
41. Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, et al. (2008) IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nature medicine 14: 275-281.
42. Hamada S, Umemura M, Shiono T, Tanaka K, Yahagi A, et al. (2008) IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver. Journal of immunology 181: 3456-3463.
43. Hamada S, Umemura M, Shiono T, Hara H, Kishihara K, et al. (2008) Importance of murine Vdelta1gammadelta T cells expressing interferon-gamma and interleukin-17A in innate protection against Listeria monocytogenes infection. Immunology 125: 170-177.
44. Geddes K, Rubino SJ, Magalhaes JG, Streutker C, Le Bourhis L, et al. (2011) Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nature medicine 17: 837-844.
45. Happel KI, Dubin PJ, Zheng M, Ghilardi N, Lockhart C, et al. (2005) Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. The Journal of experimental medicine 202: 761-769.
46. Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y, (2007) Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. Journal of immunology 178: 4466-4472.
47. Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, et al. (2008) Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nature medicine 14: 282-289.
48. Zenewicz LA, Yancopoulos GD, Valenzuela DM, Murphy AJ, Karow M, et al. (2007) Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27: 647-659.
49. Wilson MS, Feng CG, Barber DL, Yarovinsky F, Cheever AW, et al. (2010) Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections. Journal of immunology 184: 4378-4390.
50. Parsot C, (2009) Shigella type III secretion effectors: how, where, when, for what purposes? Current opinion in microbiology 12: 110-116.
51. Le Negrate G, (2011) Subversion of innate immune responses by bacterial hindrance of NF-kappaB pathway. Cellular microbiology.