Development of an Aotus nancymaae model for shigella vaccine immunogenicity and efficacy studies

Infection and Immunity

Volumn 82, Issue 5, 2014, Pages 2027-2036

  Gregory, Michael ^a   Kaminski, Robert W ^b   Lugo Roman, Luis A ^a   Carrillo, Hugo Galvez ^c   Tilley, Drake Hamilton ^a   Baldeviano, Christian ^a   Simons, Mark P ^a   Reynolds, Nathanael D ^a   Ranallo, Ryan T ^b   Suvarnapunya, Akamol E ^b   Venkatesan, Malabi M ^b   Oaks, Edwin V ^b  

^a Peru   (Peru)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c UNIVERSIDAD NACIONAL MAYOR DE SAN MARCOS   (Peru)

Author keywords

[No Author keywords available]

Indexed keywords

SHIGELLA VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AOTUS; AOTUS NANCYMAAE; ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; DRUG EFFICACY; IMMUNE RESPONSE; IMMUNITY; IMMUNOGENICITY; INFECTIOUS DIARRHEA; NONHUMAN; PILOT STUDY; PRIORITY JOURNAL; PROVOCATION TEST; SHIGELLA FLEXNERI; SHIGELLOSIS; VACCINATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; AOTIDAE; DIARRHEA; DISEASE MODELS, ANIMAL; DYSENTERY, BACILLARY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; SHIGELLA VACCINES;

EID: 84898886297     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01665-13     Document Type: Article

References (36)

1. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, et al. 2012. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2095-2128. http://dx.doi.org/10.1016/S0140-6736(12) 61728-0.
2. Kotloff KL, Winickoff JP, Ivanoff B, Clemens JD, Swerdlow DL, Sansonetti PJ, Adak GK, Levine MM. 1999. Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull. World Health Organ. 77:651-666.
3. Garrett V, Bornschlegel K, Lange D, Reddy V, Kornstein L, Kornblum J, Agasan A, Hoekstra M, Layton M, Sobel J. 2006. A recurring outbreak of Shigella sonnei among traditionally observant Jewish children in New York City: the risks of daycare and household transmission. Epidemiol. Infect. 134:1231-1236. http://dx.doi.org/10.1017/S0950268806006182.
4. Morgan O, Crook P, Cheasty T, Jiggle B, Giraudon I, Hughes H, Jones SM. 2006. Shigella sonnei outbreak among homosexual men, London. Emerg. Infect. Dis. 12:1458-1460. http://dx.doi.org/10.3201/eid1209.060282.
5. Ahmed SF, Riddle MS, Wierzba TF, Messih IA, Monteville MR, Sanders JW, Klena JD. 2006. Epidemiology and genetic characterization of Shigella flexneri strains isolated from three paediatric populations in Egypt (2000-2004). Epidemiol. Infect. 134:1237-1248. http://dx.doi.org/10.1017/S095026880600642X.
6. Riddle MS, Sanders JW, Putnam SD, Tribble DR. 2006. Incidence, etiology, and impact of diarrhea among long-term travelers (US military and similar populations): a systematic review. Am. J. Trop. Med. Hyg. 74:891-900.
7. Mallett CP, VanDeVerg L, Collins HH, Hale TL. 1993. Evaluation of Shigella vaccine safety and efficacy in an intranasally challenged mouse model. Vaccine 11:190-196. http://dx.doi.org/10.1016/0264-410X(93) 90016-Q.
8. Hartman AB, Powell CJ, Schultz CL, Oaks EV, Eckels KH. 1991. Small-animal model to measure efficacy and immunogenicity of Shigella vaccine strains. Infect. Immun. 59:4075-4083.
9. Shim DH, Suzuki T, Chang SY, Park SM, Sansonetti PJ, Sasakawa C, Kweon MN. 2007. New animal model of shigellosis in the guinea pig: its usefulness for protective efficacy studies. J. Immunol. 178:2476-2482.
10. Kent TH, Formal SB, LaBrec EH, Sprinz H, Maenza RM. 1967. Gastric shigellosis in rhesus monkeys. Am. J. Pathol. 51:259-267.
11. Formal SB, Hale TL, Kapfer C, Cogan JP, Snoy PJ, Chung R, Wingfield ME, Elisberg BL, Baron LS. 1984. Oral vaccination of monkeys with an invasive Escherichia coli K-12 hybrid expressing Shigella flexneri 2a somatic antigen. Infect. Immun. 46:465-469.
12. Takeuchi A, Jervis HR, Formal SB. 1975. Animal model of human disease. Bacillary dysentery, shigellosis, Shigella dysentery. Animal model: monkey shigellosis or dysentery. Am. J. Pathol. 81:251-254.
13. Speelman P, Kabir I, Islam M. 1984. Distribution and spread of colonic lesions in shigellosis: a colonoscopic study. J. Infect. Dis. 150:899-903. http://dx.doi.org/10.1093/infdis/150.6.899.
14. Jones FR, Baqar S, Gozalo A, Nunez G, Espinoza N, Reyes SM, Salazar M, Meza R, Porter CK, Walz SE. 2006. New World monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity. Infect. Immun. 74:790-793. http://dx.doi.org/10.1128/IAI.74.1.790-793.2006.
15. Jones FR, Hall ER, Tribble D, Savarino SJ, Cassels FJ, Porter C, Meza R, Nunez G, Espinoza N, Salazar M, Luckett R, Scott D. 2006. The New World primate, Aotus nancymae, as a model for examining the immunogenicity of a prototype enterotoxigenic Escherichia coli subunit vaccine. Vaccine 24:3786-3792. http://dx.doi.org/10.1016/j.vaccine.2005.07.029.
16. National Research Council. 2011. Guide for the care and use of laboratory animals, 8th ed. National Academies Press, Washington, DC.
17. Verma NK, Lindberg AA. 1991. Construction of aromatic dependent Shigella flexneri 2a live vaccine candidate strains: deletion mutations in the aroA and the aroD genes. Vaccine 9:6-9. http://dx.doi.org/10.1016 /0264-410X(91)90308-S.
18. Labrec EH, Schneider H, Magnani TJ, Formal SB. 1964. Epithelial cell penetration as an essential step in the pathogenesis of bacillary dysentery. J. Bacteriol. 88:1503-1518.
19. DuPont HL, Levine MM, Hornick RB, Formal SB. 1989. Inoculum size in shigellosis and implications for expected mode of transmission. J. Infect. Dis. 159:1126-1128. http://dx.doi.org/10.1093/infdis/159.6.1126.
20. Coster TS, Hoge CW, VanDeVerg LL, Hartman AB, Oaks EV, Venkatesan MM, Cohen D, Robin G, Fontaine-Thompson A, Sansonetti PJ, Hale TL. 1999. Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602. Infect. Immun. 67:3437-3443.
21. Barzu S, Fontaine A, Sansonetti P, Phalipon A. 1996. Induction of a local anti-IpaC antibody response in mice by use of a Shigella flexneri 2a vaccine candidate: implications for use of IpaC as a protein carrier. Infect. Immun. 64:1190-1196.
22. Collins TA, Barnoy S, Baqar S, Ranallo RT, Nemelka KW, Venkatesan MM. 2008. Safety and colonization of two novel VirG(IcsA)-based live Shigella sonnei vaccine strains in rhesus macaques (Macaca mulatta). Comp. Med. 58:88-94.
23. Mills JA, Buysse JM, Oaks EV. 1988. Shigella flexneri invasion plasmid antigens B and C: epitope location and characterization with monoclonal antibodies. Infect. Immun. 56:2933-2941.
24. Kaminski RW, Turbyfill KR, Oaks EV. 2006. Mucosal adjuvant properties of the Shigella invasin complex. Infect. Immun. 74:2856-2866. http: //dx.doi.org/10.1128/IAI.74.5.2856-2866.2006.
25. Turbyfill KR, Hartman AB, Oaks EV. 2000. Isolation and characterization of a Shigella flexneri invasin complex subunit vaccine. Infect. Immun. 68:6624-6632. http://dx.doi.org/10.1128/IAI.68.12.6624-6632.2000.
26. Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF, Faruque AS, Zaidi AK, Saha D, Alonso PL, Tamboura B, Sanogo D, Onwuchekwa U, Manna B, Ramamurthy T, Kanungo S, Ochieng JB, Omore R, Oundo JO, Hossain A, Das SK, Ahmed S, Qureshi S, Quadri F, Adegbola RA, Antonio M, Hossain MJ, Akinsola A, Mandomando I, Nhampossa T, Acacio S, Biswas K, O'Reilly CE, Mintz ED, Berkeley LY, Muhsen K, Sommerfelt H, Robins-Browne RM, Levine MM. 2013. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet 382:209-222. http://dx.doi.org/10.1016/S0140 -6736(13)60844-2.
27. Monteiro MA, Baqar S, Hall ER, Chen YH, Porter CK, Bentzel DE, Applebee L, Guerry P. 2009. Capsule polysaccharide conjugate vaccine against diarrheal disease caused by Campylobacter jejuni. Infect. Immun. 77:1128-1136. http://dx.doi.org/10.1128/IAI.01056-08.
28. Karnell A, Cam PD, Verma N, Lindberg AA. 1993. AroD deletion attenuates Shigella flexneri strain 2457T and makes it a safe and efficacious oral vaccine in monkeys. Vaccine 11:830-836. http://dx.doi.org/10.1016 /0264-410X(93)90358-5.
29. Kotloff KL, Herrington DA, Hale TL, Newland JW, Van De Verg L, Cogan JP, Snoy PJ, Sadoff JC, Formal SB, Levine MM. 1992. Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen. Infect. Immun. 60:2218-2224.
30. Dinari G, Hale TL, Austin SW, Formal SB. 1987. Local and systemic antibody responses to Shigella infection in rhesus monkeys. J. Infect. Dis. 155:1065-1069. http://dx.doi.org/10.1093/infdis/155.5.1065.
31. Rout WR, Formal SB, Giannella RA, Dammin GJ. 1975. Pathophysiology of Shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studies. Gastroenterology 68:270-278.
32. Formal SB, Oaks EV, Olsen RE, Wingfield-Eggleston M, Snoy PJ, Cogan JP. 1991. Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subsequent infection with Shigella sonnei. J. Infect. Dis. 164:533-537. http://dx.doi.org/10.1093/infdis/164.3.533.
33. Katakura S, Reinholt FP, Karnell A, Huan PT, Trach DD, Lindberg AA. 1990. The pathology of Shigella flexneri infection in rhesus monkeys: an endoscopic and histopathological study of colonic lesions. APMIS 98: 313-319. http://dx.doi.org/10.1111/j.1699-0463.1990.tb01038.x.
34. Takeuchi A. 1982. Early colonic lesions in experimental Shigella infection in rhesus monkeys: revisited. Vet. Pathol. Suppl. 19(Suppl 7):1-8. http: //dx.doi.org/10.1177/030098588201907s01.
35. Shipley ST, Panda A, Khan AQ, Kriel EH, Maciel M, Jr, Livio S, Nataro JP, Levine MM, Sztein MB, DeTolla LJ. 2010. A challenge model for Shigella dysenteriae 1 in cynomolgus monkeys (Macaca fascicularis). Comp. Med. 60:54-61.
36. Katz DE, Coster TS, Wolf MK, Trespalacios FC, Cohen D, Robins G, Hartman AB, Venkatesan MM, Taylor DN, Hale TL. 2004. Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers. Infect. Immun. 72:923-930. http://dx.doi.org/10.1128/IAI.72.2.923-930.2004.