PTEN Overexpression Cooperates with Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells

Journal of Cellular Biochemistry

Volumn 117, Issue 2, 2016, Pages 458-469

  De Araujo, Wallace Martins ^a   Robbs, Bruno Kaufmann ^b   Bastos, Lilian G ^a   De Souza, Waldemir F ^a   Vidal, Flávia C B ^c   Viola, João P B ^a   Morgado Diaz, Jose A ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF MARANHÃO   (Brazil)

Author keywords

COLORECTAL CANCER; LITHIUM; PI3K Akt; PTEN

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; ANTINEOPLASTIC AGENT; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, HUMAN; LITHIUM CHLORIDE; PTEN PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; COLORECTAL CANCER; CONTROLLED STUDY; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR INVASION; CELL ADHESION; CELL MOTION; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HCT 116 CELL LINE; HT-29 CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; GENE EXPRESSION; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HCT116 CELLS; HT29 CELLS; HUMANS; LITHIUM CHLORIDE; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84956659519     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25294     Document Type: Article

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