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Volumn 28, Issue 6, 2015, Pages 690-714

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

Author keywords

Checkpoint blockade; Immune contexture; Immunogenic cell death; Natural killer cells; Tumor associated macrophages; Tumor infiltrating lymphocytes

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOLOGIC FACTOR;

EID: 84956607773     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.10.012     Document Type: Review
Times cited : (1231)

References (210)
  • 1
    • 84892686102 scopus 로고    scopus 로고
    • Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer
    • Alizadeh D., Trad M., Hanke N.T., Larmonier C.B., Janikashvili N., Bonnotte B., Katsanis E., Larmonier N. Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer. Cancer Res. 2014, 74:104-118.
    • (2014) Cancer Res. , vol.74 , pp. 104-118
    • Alizadeh, D.1    Trad, M.2    Hanke, N.T.3    Larmonier, C.B.4    Janikashvili, N.5    Bonnotte, B.6    Katsanis, E.7    Larmonier, N.8
  • 2
    • 84907069550 scopus 로고    scopus 로고
    • Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function
    • Amiel E., Everts B., Fritz D., Beauchamp S., Ge B., Pearce E.L., Pearce E.J. Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function. J. Immunol. 2014, 193:2821-2830.
    • (2014) J. Immunol. , vol.193 , pp. 2821-2830
    • Amiel, E.1    Everts, B.2    Fritz, D.3    Beauchamp, S.4    Ge, B.5    Pearce, E.L.6    Pearce, E.J.7
  • 11
    • 84896492317 scopus 로고    scopus 로고
    • Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8(+) T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model
    • Bauer C., Sterzik A., Bauernfeind F., Duewell P., Conrad C., Kiefl R., Endres S., Eigler A., Schnurr M., Dauer M. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8(+) T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model. Cancer Immunol. Immunother. 2014, 63:321-333.
    • (2014) Cancer Immunol. Immunother. , vol.63 , pp. 321-333
    • Bauer, C.1    Sterzik, A.2    Bauernfeind, F.3    Duewell, P.4    Conrad, C.5    Kiefl, R.6    Endres, S.7    Eigler, A.8    Schnurr, M.9    Dauer, M.10
  • 15
    • 84890111958 scopus 로고    scopus 로고
    • Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer
    • Bracci L., Schiavoni G., Sistigu A., Belardelli F. Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer. Cell Death Differ. 2014, 21:15-25.
    • (2014) Cell Death Differ. , vol.21 , pp. 15-25
    • Bracci, L.1    Schiavoni, G.2    Sistigu, A.3    Belardelli, F.4
  • 16
    • 84882827495 scopus 로고    scopus 로고
    • Decoding cell death signals in liver inflammation
    • Brenner C., Galluzzi L., Kepp O., Kroemer G. Decoding cell death signals in liver inflammation. J. Hepatol. 2013, 59:583-594.
    • (2013) J. Hepatol. , vol.59 , pp. 583-594
    • Brenner, C.1    Galluzzi, L.2    Kepp, O.3    Kroemer, G.4
  • 20
    • 84884523966 scopus 로고    scopus 로고
    • Ibrutinib in relapsed chronic lymphocytic leukemia
    • Byrd J.C., O'Brien S., James D.F. Ibrutinib in relapsed chronic lymphocytic leukemia. N. Engl. J. Med. 2013, 369:1278-1279.
    • (2013) N. Engl. J. Med. , vol.369 , pp. 1278-1279
    • Byrd, J.C.1    O'Brien, S.2    James, D.F.3
  • 21
    • 84949322531 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity
    • Published online March 9, 2015
    • Cao K., Wang G., Li W., Zhang L., Wang R., Huang Y., Du L., Jiang J., Wu C., He X., et al. Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity. Oncogene 2015, Published online March 9, 2015. 10.1038/onc.2015.46.
    • (2015) Oncogene
    • Cao, K.1    Wang, G.2    Li, W.3    Zhang, L.4    Wang, R.5    Huang, Y.6    Du, L.7    Jiang, J.8    Wu, C.9    He, X.10
  • 25
    • 84925013050 scopus 로고    scopus 로고
    • Suppressive effects of gemcitabine plus cisplatin chemotherapy on regulatory T cells in nonsmall-cell lung cancer
    • Chen C., Chen Z., Chen D., Zhang B., Wang Z., Le H. Suppressive effects of gemcitabine plus cisplatin chemotherapy on regulatory T cells in nonsmall-cell lung cancer. J. Int. Med. Res. 2015, 43:180-187.
    • (2015) J. Int. Med. Res. , vol.43 , pp. 180-187
    • Chen, C.1    Chen, Z.2    Chen, D.3    Zhang, B.4    Wang, Z.5    Le, H.6
  • 27
    • 84925969185 scopus 로고    scopus 로고
    • Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: results from COMPARZ, a randomized controlled trial
    • Choueiri T.K., Figueroa D.J., Fay A.P., Signoretti S., Liu Y., Gagnon R., Deen K., Carpenter C., Benson P., Ho T.H., et al. Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: results from COMPARZ, a randomized controlled trial. Clin. Cancer Res. 2015, 21:1071-1077.
    • (2015) Clin. Cancer Res. , vol.21 , pp. 1071-1077
    • Choueiri, T.K.1    Figueroa, D.J.2    Fay, A.P.3    Signoretti, S.4    Liu, Y.5    Gagnon, R.6    Deen, K.7    Carpenter, C.8    Benson, P.9    Ho, T.H.10
  • 28
    • 84930183507 scopus 로고    scopus 로고
    • PRRs are watching you: Localization of innate sensing and signaling regulators
    • Chow J., Franz K.M., Kagan J.C. PRRs are watching you: Localization of innate sensing and signaling regulators. Virology 2015, 479-480:104-109.
    • (2015) Virology , vol.479-480 , pp. 104-109
    • Chow, J.1    Franz, K.M.2    Kagan, J.C.3
  • 29
    • 84908047017 scopus 로고    scopus 로고
    • Serial low doses of sorafenib enhance therapeutic efficacy of adoptive T cell therapy in a murine model by improving tumor microenvironment
    • Chuang H.Y., Chang Y.F., Liu R.S., Hwang J.J. Serial low doses of sorafenib enhance therapeutic efficacy of adoptive T cell therapy in a murine model by improving tumor microenvironment. PLoS ONE 2014, 9:e109992.
    • (2014) PLoS ONE , vol.9
    • Chuang, H.Y.1    Chang, Y.F.2    Liu, R.S.3    Hwang, J.J.4
  • 31
    • 84872445265 scopus 로고    scopus 로고
    • Neutralizing tumor-promoting chronic inflammation: a magic bullet?
    • Coussens L.M., Zitvogel L., Palucka A.K. Neutralizing tumor-promoting chronic inflammation: a magic bullet?. Science 2013, 339:286-291.
    • (2013) Science , vol.339 , pp. 286-291
    • Coussens, L.M.1    Zitvogel, L.2    Palucka, A.K.3
  • 32
    • 84928619890 scopus 로고    scopus 로고
    • Methotrexate restores regulatory T cell function through demethylation of the FoxP3 upstream enhancer in patients with rheumatoid arthritis
    • Cribbs A.P., Kennedy A., Penn H., Amjadi P., Green P., Read J.E., Brennan F., Gregory B., Williams R.O. Methotrexate restores regulatory T cell function through demethylation of the FoxP3 upstream enhancer in patients with rheumatoid arthritis. Arthritis Rheumatol. 2015, 67:1182-1192.
    • (2015) Arthritis Rheumatol. , vol.67 , pp. 1182-1192
    • Cribbs, A.P.1    Kennedy, A.2    Penn, H.3    Amjadi, P.4    Green, P.5    Read, J.E.6    Brennan, F.7    Gregory, B.8    Williams, R.O.9
  • 33
    • 84937577488 scopus 로고    scopus 로고
    • Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis
    • Cullen S.P., Kearney C.J., Clancy D.M., Martin S.J. Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis. Cell Rep. 2015, 11:1535-1548.
    • (2015) Cell Rep. , vol.11 , pp. 1535-1548
    • Cullen, S.P.1    Kearney, C.J.2    Clancy, D.M.3    Martin, S.J.4
  • 36
    • 79952724783 scopus 로고    scopus 로고
    • Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
    • De Monte L., Reni M., Tassi E., Clavenna D., Papa I., Recalde H., Braga M., Di Carlo V., Doglioni C., Protti M.P. Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J. Exp. Med. 2011, 208:469-478.
    • (2011) J. Exp. Med. , vol.208 , pp. 469-478
    • De Monte, L.1    Reni, M.2    Tassi, E.3    Clavenna, D.4    Papa, I.5    Recalde, H.6    Braga, M.7    Di Carlo, V.8    Doglioni, C.9    Protti, M.P.10
  • 41
    • 84927138902 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers
    • Denkert C., von Minckwitz G., Brase J.C., Sinn B.V., Gade S., Kronenwett R., Pfitzner B.M., Salat C., Loi S., Schmitt W.D., et al. Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers. J. Clin. Oncol. 2015, 33:983-991.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 983-991
    • Denkert, C.1    von Minckwitz, G.2    Brase, J.C.3    Sinn, B.V.4    Gade, S.5    Kronenwett, R.6    Pfitzner, B.M.7    Salat, C.8    Loi, S.9    Schmitt, W.D.10
  • 43
    • 84937597495 scopus 로고    scopus 로고
    • Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy
    • Di Caro G., Cortese N., Castino G.F., Grizzi F., Gavazzi F., Ridolfi C., Capretti G., Mineri R., Todoric J., Zerbi A., et al. Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy. Gut 2015, 10.1136/gutjnl-2015-309193.
    • (2015) Gut
    • Di Caro, G.1    Cortese, N.2    Castino, G.F.3    Grizzi, F.4    Gavazzi, F.5    Ridolfi, C.6    Capretti, G.7    Mineri, R.8    Todoric, J.9    Zerbi, A.10
  • 45
    • 84924292037 scopus 로고    scopus 로고
    • Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis
    • Dimeloe S., Frick C., Fischer M., Gubser P.M., Razik L., Bantug G.R., Ravon M., Langenkamp A., Hess C. Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis. Eur. J. Immunol. 2014, 44:3614-3620.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 3614-3620
    • Dimeloe, S.1    Frick, C.2    Fischer, M.3    Gubser, P.M.4    Razik, L.5    Bantug, G.R.6    Ravon, M.7    Langenkamp, A.8    Hess, C.9
  • 46
    • 84903990337 scopus 로고    scopus 로고
    • Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis
    • Ding Z.C., Lu X., Yu M., Lemos H., Huang L., Chandler P., Liu K., Walters M., Krasinski A., Mack M., et al. Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res. 2014, 74:3441-3453.
    • (2014) Cancer Res. , vol.74 , pp. 3441-3453
    • Ding, Z.C.1    Lu, X.2    Yu, M.3    Lemos, H.4    Huang, L.5    Chandler, P.6    Liu, K.7    Walters, M.8    Krasinski, A.9    Mack, M.10
  • 47
    • 70350450778 scopus 로고    scopus 로고
    • Perspectives on the development of imatinib and the future of cancer research
    • Druker B.J. Perspectives on the development of imatinib and the future of cancer research. Nat. Med. 2009, 15:1149-1152.
    • (2009) Nat. Med. , vol.15 , pp. 1149-1152
    • Druker, B.J.1
  • 51
    • 84900860181 scopus 로고    scopus 로고
    • Cross-Talks between Natural Killer Cells and Distinct Subsets of Dendritic Cells
    • Ferlazzo G., Morandi B. Cross-Talks between Natural Killer Cells and Distinct Subsets of Dendritic Cells. Front. Immunol. 2014, 5:159.
    • (2014) Front. Immunol. , vol.5 , pp. 159
    • Ferlazzo, G.1    Morandi, B.2
  • 53
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • Finn O.J. Cancer immunology. N. Engl. J. Med. 2008, 358:2704-2715.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2704-2715
    • Finn, O.J.1
  • 54
    • 84874872137 scopus 로고    scopus 로고
    • BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
    • Frederick D.T., Piris A., Cogdill A.P., Cooper Z.A., Lezcano C., Ferrone C.R., Mitra D., Boni A., Newton L.P., Liu C., et al. BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma. Clin. Cancer Res. 2013, 19:1225-1231.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 1225-1231
    • Frederick, D.T.1    Piris, A.2    Cogdill, A.P.3    Cooper, Z.A.4    Lezcano, C.5    Ferrone, C.R.6    Mitra, D.7    Boni, A.8    Newton, L.P.9    Liu, C.10
  • 55
  • 62
    • 84879525182 scopus 로고    scopus 로고
    • The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a tumor model system
    • Geary S.M., Lemke C.D., Lubaroff D.M., Salem A.K. The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a tumor model system. PLoS ONE 2013, 8:e67904.
    • (2013) PLoS ONE , vol.8
    • Geary, S.M.1    Lemke, C.D.2    Lubaroff, D.M.3    Salem, A.K.4
  • 63
    • 84997611267 scopus 로고    scopus 로고
    • Immune modulating effects of cyclophosphamide and treatment with tumor lysate/CpG synergize to eliminate murine neuroblastoma
    • Gershan J.A., Barr K.M., Weber J.J., Jing W., Johnson B.D. Immune modulating effects of cyclophosphamide and treatment with tumor lysate/CpG synergize to eliminate murine neuroblastoma. J. Immunother. Cancer 2015, 3:24.
    • (2015) J. Immunother. Cancer , vol.3 , pp. 24
    • Gershan, J.A.1    Barr, K.M.2    Weber, J.J.3    Jing, W.4    Johnson, B.D.5
  • 71
    • 84870429963 scopus 로고    scopus 로고
    • Transplantation: Sirolimus for secondary SCC prevention in renal transplantation
    • Halleck F., Budde K. Transplantation: Sirolimus for secondary SCC prevention in renal transplantation. Nat. Rev. Nephrol. 2012, 8:687-689.
    • (2012) Nat. Rev. Nephrol. , vol.8 , pp. 687-689
    • Halleck, F.1    Budde, K.2
  • 74
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 76
    • 84881288707 scopus 로고    scopus 로고
    • Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation
    • He S., Yin T., Li D., Gao X., Wan Y., Ma X., Ye T., Guo F., Sun J., Lin Z., Wang Y. Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation. J. Transl. Med. 2013, 11:186.
    • (2013) J. Transl. Med. , vol.11 , pp. 186
    • He, S.1    Yin, T.2    Li, D.3    Gao, X.4    Wan, Y.5    Ma, X.6    Ye, T.7    Guo, F.8    Sun, J.9    Lin, Z.10    Wang, Y.11
  • 77
    • 84903464388 scopus 로고    scopus 로고
    • Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ
    • Ho P.C., Meeth K.M., Tsui Y.C., Srivastava B., Bosenberg M.W., Kaech S.M. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. Cancer Res. 2014, 74:3205-3217.
    • (2014) Cancer Res. , vol.74 , pp. 3205-3217
    • Ho, P.C.1    Meeth, K.M.2    Tsui, Y.C.3    Srivastava, B.4    Bosenberg, M.W.5    Kaech, S.M.6
  • 78
    • 84878016733 scopus 로고    scopus 로고
    • Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death
    • Hodge J.W., Garnett C.T., Farsaci B., Palena C., Tsang K.Y., Ferrone S., Gameiro S.R. Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death. Int. J. Cancer 2013, 133:624-636.
    • (2013) Int. J. Cancer , vol.133 , pp. 624-636
    • Hodge, J.W.1    Garnett, C.T.2    Farsaci, B.3    Palena, C.4    Tsang, K.Y.5    Ferrone, S.6    Gameiro, S.R.7
  • 79
    • 84896697749 scopus 로고    scopus 로고
    • Changes in the immune cell population and cell proliferation in peripheral blood after gemcitabine-based chemotherapy for pancreatic cancer
    • Homma Y., Taniguchi K., Nakazawa M., Matsuyama R., Mori R., Takeda K., Ichikawa Y., Tanaka K., Endo I. Changes in the immune cell population and cell proliferation in peripheral blood after gemcitabine-based chemotherapy for pancreatic cancer. Clin. Transl. Oncol. 2014, 16:330-335.
    • (2014) Clin. Transl. Oncol. , vol.16 , pp. 330-335
    • Homma, Y.1    Taniguchi, K.2    Nakazawa, M.3    Matsuyama, R.4    Mori, R.5    Takeda, K.6    Ichikawa, Y.7    Tanaka, K.8    Endo, I.9
  • 81
    • 84928705533 scopus 로고    scopus 로고
    • VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation
    • Huang H., Langenkamp E., Georganaki M., Loskog A., Fuchs P.F., Dieterich L.C., Kreuger J., Dimberg A. VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation. FASEB J. 2015, 29:227-238.
    • (2015) FASEB J. , vol.29 , pp. 227-238
    • Huang, H.1    Langenkamp, E.2    Georganaki, M.3    Loskog, A.4    Fuchs, P.F.5    Dieterich, L.C.6    Kreuger, J.7    Dimberg, A.8
  • 83
    • 84939526522 scopus 로고    scopus 로고
    • Early cytotoxic lymphocyte expansion contributes to a deep molecular response to dasatinib in patients with newly diagnosed chronic myeloid leukemia in the chronic phase: results of the D-first study
    • Iriyama N., Fujisawa S., Yoshida C., Wakita H., Chiba S., Okamoto S., Kawakami K., Takezako N., Kumagai T., Inokuchi K., et al. Early cytotoxic lymphocyte expansion contributes to a deep molecular response to dasatinib in patients with newly diagnosed chronic myeloid leukemia in the chronic phase: results of the D-first study. Am. J. Hematol. 2015, 90:819-824.
    • (2015) Am. J. Hematol. , vol.90 , pp. 819-824
    • Iriyama, N.1    Fujisawa, S.2    Yoshida, C.3    Wakita, H.4    Chiba, S.5    Okamoto, S.6    Kawakami, K.7    Takezako, N.8    Kumagai, T.9    Inokuchi, K.10
  • 84
    • 84891590308 scopus 로고    scopus 로고
    • Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer--a substudy of the neoadjuvant GeparQuinto trial
    • Issa-Nummer Y., Darb-Esfahani S., Loibl S., Kunz G., Nekljudova V., Schrader I., Sinn B.V., Ulmer H.U., Kronenwett R., Just M., et al. Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer--a substudy of the neoadjuvant GeparQuinto trial. PLoS ONE 2013, 8:e79775.
    • (2013) PLoS ONE , vol.8
    • Issa-Nummer, Y.1    Darb-Esfahani, S.2    Loibl, S.3    Kunz, G.4    Nekljudova, V.5    Schrader, I.6    Sinn, B.V.7    Ulmer, H.U.8    Kronenwett, R.9    Just, M.10
  • 85
    • 84860366086 scopus 로고    scopus 로고
    • Antiangiogenic therapy--evolving view based on clinical trial results
    • Jayson G.C., Hicklin D.J., Ellis L.M. Antiangiogenic therapy--evolving view based on clinical trial results. Nat. Rev. Clin. Oncol. 2012, 9:297-303.
    • (2012) Nat. Rev. Clin. Oncol. , vol.9 , pp. 297-303
    • Jayson, G.C.1    Hicklin, D.J.2    Ellis, L.M.3
  • 86
    • 77649181500 scopus 로고    scopus 로고
    • Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer
    • Jenq R.R., van den Brink M.R. Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer. Nat. Rev. Cancer 2010, 10:213-221.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 213-221
    • Jenq, R.R.1    van den Brink, M.R.2
  • 89
    • 84876961766 scopus 로고    scopus 로고
    • Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity
    • Kang T.H., Mao C.P., Lee S.Y., Chen A., Lee J.H., Kim T.W., Alvarez R.D., Roden R.B., Pardoll D., Hung C.F., Wu T.C. Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity. Cancer Res. 2013, 73:2493-2504.
    • (2013) Cancer Res. , vol.73 , pp. 2493-2504
    • Kang, T.H.1    Mao, C.P.2    Lee, S.Y.3    Chen, A.4    Lee, J.H.5    Kim, T.W.6    Alvarez, R.D.7    Roden, R.B.8    Pardoll, D.9    Hung, C.F.10    Wu, T.C.11
  • 90
    • 84909608106 scopus 로고    scopus 로고
    • Adverse immunoregulatory effects of 5FU and CPT11 chemotherapy on myeloid-derived suppressor cells and colorectal cancer outcomes
    • Kanterman J., Sade-Feldman M., Biton M., Ish-Shalom E., Lasry A., Goldshtein A., Hubert A., Baniyash M. Adverse immunoregulatory effects of 5FU and CPT11 chemotherapy on myeloid-derived suppressor cells and colorectal cancer outcomes. Cancer Res. 2014, 74:6022-6035.
    • (2014) Cancer Res. , vol.74 , pp. 6022-6035
    • Kanterman, J.1    Sade-Feldman, M.2    Biton, M.3    Ish-Shalom, E.4    Lasry, A.5    Goldshtein, A.6    Hubert, A.7    Baniyash, M.8
  • 93
    • 38049022492 scopus 로고    scopus 로고
    • The ratio of FOXP3+ regulatory T cells to granzyme B+ cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression
    • Kelley T.W., Pohlman B., Elson P., Hsi E.D. The ratio of FOXP3+ regulatory T cells to granzyme B+ cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression. Am. J. Clin. Pathol. 2007, 128:958-965.
    • (2007) Am. J. Clin. Pathol. , vol.128 , pp. 958-965
    • Kelley, T.W.1    Pohlman, B.2    Elson, P.3    Hsi, E.D.4
  • 95
    • 84858755173 scopus 로고    scopus 로고
    • 5-Fluorouracil and interferon-α immunochemotherapy enhances immunogenicity of murine pancreatic cancer through upregulation of NKG2D ligands and MHC class I
    • Khallouf H., Märten A., Serba S., Teichgräber V., Büchler M.W., Jäger D., Schmidt J. 5-Fluorouracil and interferon-α immunochemotherapy enhances immunogenicity of murine pancreatic cancer through upregulation of NKG2D ligands and MHC class I. J. Immunother. 2012, 35:245-253.
    • (2012) J. Immunother. , vol.35 , pp. 245-253
    • Khallouf, H.1    Märten, A.2    Serba, S.3    Teichgräber, V.4    Büchler, M.W.5    Jäger, D.6    Schmidt, J.7
  • 99
    • 67650504854 scopus 로고    scopus 로고
    • Therapy: methotrexate guidelines: compromise to reach consensus
    • Kremer J.M. Therapy: methotrexate guidelines: compromise to reach consensus. Nat. Rev. Rheumatol. 2009, 5:186-187.
    • (2009) Nat. Rev. Rheumatol. , vol.5 , pp. 186-187
    • Kremer, J.M.1
  • 105
    • 84925625990 scopus 로고    scopus 로고
    • On being less tolerant: enhanced cancer immunosurveillance enabled by targeting checkpoints and agonists of T cell activation
    • 280sr1
    • Lesokhin A.M., Callahan M.K., Postow M.A., Wolchok J.D. On being less tolerant: enhanced cancer immunosurveillance enabled by targeting checkpoints and agonists of T cell activation. Sci. Transl. Med. 2015, 7:280sr1.
    • (2015) Sci. Transl. Med. , vol.7
    • Lesokhin, A.M.1    Callahan, M.K.2    Postow, M.A.3    Wolchok, J.D.4
  • 109
    • 84901044443 scopus 로고    scopus 로고
    • Selective depletion of regulatory T cell subsets by docetaxel treatment in patients with nonsmall cell lung cancer
    • Li J.Y., Duan X.F., Wang L.P., Xu Y.J., Huang L., Zhang T.F., Liu J.Y., Li F., Zhang Z., Yue D.L., et al. Selective depletion of regulatory T cell subsets by docetaxel treatment in patients with nonsmall cell lung cancer. J. Immunol. Res. 2014, 2014:286170.
    • (2014) J. Immunol. Res. , vol.2014 , pp. 286170
    • Li, J.Y.1    Duan, X.F.2    Wang, L.P.3    Xu, Y.J.4    Huang, L.5    Zhang, T.F.6    Liu, J.Y.7    Li, F.8    Zhang, Z.9    Yue, D.L.10
  • 111
  • 113
    • 74249120625 scopus 로고    scopus 로고
    • Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses
    • Liu W.M., Fowler D.W., Smith P., Dalgleish A.G. Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses. Br. J. Cancer 2010, 102:115-123.
    • (2010) Br. J. Cancer , vol.102 , pp. 115-123
    • Liu, W.M.1    Fowler, D.W.2    Smith, P.3    Dalgleish, A.G.4
  • 114
    • 84872514398 scopus 로고    scopus 로고
    • BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice
    • Liu C., Peng W., Xu C., Lou Y., Zhang M., Wargo J.A., Chen J.Q., Li H.S., Watowich S.S., Yang Y., et al. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin. Cancer Res. 2013, 19:393-403.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 393-403
    • Liu, C.1    Peng, W.2    Xu, C.3    Lou, Y.4    Zhang, M.5    Wargo, J.A.6    Chen, J.Q.7    Li, H.S.8    Watowich, S.S.9    Yang, Y.10
  • 115
    • 84927666190 scopus 로고    scopus 로고
    • The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4
    • Liu L., Mayes P.A., Eastman S., Shi H., Yadavilli S., Zhang T., Yang J., Seestaller-Wehr L., Zhang S.Y., Hopson C., et al. The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4. Clin. Cancer Res. 2015, 21:1639-1651.
    • (2015) Clin. Cancer Res. , vol.21 , pp. 1639-1651
    • Liu, L.1    Mayes, P.A.2    Eastman, S.3    Shi, H.4    Yadavilli, S.5    Zhang, T.6    Yang, J.7    Seestaller-Wehr, L.8    Zhang, S.Y.9    Hopson, C.10
  • 116
    • 84899073185 scopus 로고    scopus 로고
    • Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma
    • Lowe D.B., Bose A., Taylor J.L., Tawbi H., Lin Y., Kirkwood J.M., Storkus W.J. Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma. OncoImmunology 2014, 3:e27589.
    • (2014) OncoImmunology , vol.3
    • Lowe, D.B.1    Bose, A.2    Taylor, J.L.3    Tawbi, H.4    Lin, Y.5    Kirkwood, J.M.6    Storkus, W.J.7
  • 117
    • 61449182121 scopus 로고    scopus 로고
    • Principles of cancer therapy: oncogene and non-oncogene addiction
    • Luo J., Solimini N.L., Elledge S.J. Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 2009, 136:823-837.
    • (2009) Cell , vol.136 , pp. 823-837
    • Luo, J.1    Solimini, N.L.2    Elledge, S.J.3
  • 118
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study
    • Lynch T.J., Bondarenko I., Luft A., Serwatowski P., Barlesi F., Chacko R., Sebastian M., Neal J., Lu H., Cuillerot J.M., Reck M. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J. Clin. Oncol. 2012, 30:2046-2054.
    • (2012) J. Clin. Oncol. , vol.30 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3    Serwatowski, P.4    Barlesi, F.5    Chacko, R.6    Sebastian, M.7    Neal, J.8    Lu, H.9    Cuillerot, J.M.10    Reck, M.11
  • 124
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 1994, 12:991-1045.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 125
    • 84920982588 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy
    • McDonnell A.M., Lesterhuis W.J., Khong A., Nowak A.K., Lake R.A., Currie A.J., Robinson B.W. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. Eur. J. Immunol. 2015, 45:49-59.
    • (2015) Eur. J. Immunol. , vol.45 , pp. 49-59
    • McDonnell, A.M.1    Lesterhuis, W.J.2    Khong, A.3    Nowak, A.K.4    Lake, R.A.5    Currie, A.J.6    Robinson, B.W.7
  • 126
    • 65949085379 scopus 로고    scopus 로고
    • Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients
    • Ménard C., Blay J.Y., Borg C., Michiels S., Ghiringhelli F., Robert C., Nonn C., Chaput N., Taïeb J., Delahaye N.F., et al. Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients. Cancer Res. 2009, 69:3563-3569.
    • (2009) Cancer Res. , vol.69 , pp. 3563-3569
    • Ménard, C.1    Blay, J.Y.2    Borg, C.3    Michiels, S.4    Ghiringhelli, F.5    Robert, C.6    Nonn, C.7    Chaput, N.8    Taïeb, J.9    Delahaye, N.F.10
  • 129
    • 84929203964 scopus 로고    scopus 로고
    • Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients
    • Mignot G., Hervieu A., Vabres P., Dalac S., Jeudy G., Bel B., Apetoh L., Ghiringhelli F. Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients. PLoS ONE 2014, 9:e105907.
    • (2014) PLoS ONE , vol.9
    • Mignot, G.1    Hervieu, A.2    Vabres, P.3    Dalac, S.4    Jeudy, G.5    Bel, B.6    Apetoh, L.7    Ghiringhelli, F.8
  • 133
    • 84884589344 scopus 로고    scopus 로고
    • The relationship between lymphocyte subsets and clinico-pathological determinants of survival in patients with primary operable invasive ductal breast cancer
    • Mohammed Z.M., Going J.J., Edwards J., Elsberger B., McMillan D.C. The relationship between lymphocyte subsets and clinico-pathological determinants of survival in patients with primary operable invasive ductal breast cancer. Br. J. Cancer 2013, 109:1676-1684.
    • (2013) Br. J. Cancer , vol.109 , pp. 1676-1684
    • Mohammed, Z.M.1    Going, J.J.2    Edwards, J.3    Elsberger, B.4    McMillan, D.C.5
  • 134
    • 84908676243 scopus 로고    scopus 로고
    • NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors
    • Morisaki T., Hirano T., Koya N., Kiyota A., Tanaka H., Umebayashi M., Onishi H., Katano M. NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors. Anticancer Res. 2014, 34:4529-4538.
    • (2014) Anticancer Res. , vol.34 , pp. 4529-4538
    • Morisaki, T.1    Hirano, T.2    Koya, N.3    Kiyota, A.4    Tanaka, H.5    Umebayashi, M.6    Onishi, H.7    Katano, M.8
  • 135
    • 84902081932 scopus 로고    scopus 로고
    • Schedule-dependent therapeutic efficacy of L19mTNF-α and melphalan combined with gemcitabine
    • Mortara L., Orecchia P., Castellani P., Borsi L., Carnemolla B., Balza E. Schedule-dependent therapeutic efficacy of L19mTNF-α and melphalan combined with gemcitabine. Cancer Med. 2013, 2:478-487.
    • (2013) Cancer Med. , vol.2 , pp. 478-487
    • Mortara, L.1    Orecchia, P.2    Castellani, P.3    Borsi, L.4    Carnemolla, B.5    Balza, E.6
  • 138
    • 84885590203 scopus 로고    scopus 로고
    • Immune parameters in the prognosis and therapy monitoring of cutaneous melanoma patients: experience, role, and limitations
    • Neagu M., Constantin C., Zurac S. Immune parameters in the prognosis and therapy monitoring of cutaneous melanoma patients: experience, role, and limitations. BioMed Res. Int. 2013, 2013:107940.
    • (2013) BioMed Res. Int. , vol.2013 , pp. 107940
    • Neagu, M.1    Constantin, C.2    Zurac, S.3
  • 139
    • 84923100832 scopus 로고    scopus 로고
    • New insights into tumor immunity revealed by the unique genetic and genomic aspects of ovarian cancer
    • Nelson B.H. New insights into tumor immunity revealed by the unique genetic and genomic aspects of ovarian cancer. Curr. Opin. Immunol. 2015, 33:93-100.
    • (2015) Curr. Opin. Immunol. , vol.33 , pp. 93-100
    • Nelson, B.H.1
  • 140
    • 79952998099 scopus 로고    scopus 로고
    • A comparison of mortality and costs associated with FOLFOX versus FOLFIRI in stage IV colorectal cancer
    • Nelson M.A., Shetty S., Kulakodlu M., Harley C., Seal B. A comparison of mortality and costs associated with FOLFOX versus FOLFIRI in stage IV colorectal cancer. J. Med. Econ. 2011, 14:179-186.
    • (2011) J. Med. Econ. , vol.14 , pp. 179-186
    • Nelson, M.A.1    Shetty, S.2    Kulakodlu, M.3    Harley, C.4    Seal, B.5
  • 141
    • 84906352952 scopus 로고    scopus 로고
    • Infiltration of CD8+ lymphocytes is an independent prognostic factor of biochemical failure-free survival in prostate cancer
    • Ness N., Andersen S., Valkov A., Nordby Y., Donnem T., Al-Saad S., Busund L.T., Bremnes R.M., Richardsen E. Infiltration of CD8+ lymphocytes is an independent prognostic factor of biochemical failure-free survival in prostate cancer. Prostate 2014, 74:1452-1461.
    • (2014) Prostate , vol.74 , pp. 1452-1461
    • Ness, N.1    Andersen, S.2    Valkov, A.3    Nordby, Y.4    Donnem, T.5    Al-Saad, S.6    Busund, L.T.7    Bremnes, R.M.8    Richardsen, E.9
  • 142
    • 0038326676 scopus 로고    scopus 로고
    • Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells
    • Nowak A.K., Lake R.A., Marzo A.L., Scott B., Heath W.R., Collins E.J., Frelinger J.A., Robinson B.W. Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells. J. Immunol. 2003, 170:4905-4913.
    • (2003) J. Immunol. , vol.170 , pp. 4905-4913
    • Nowak, A.K.1    Lake, R.A.2    Marzo, A.L.3    Scott, B.4    Heath, W.R.5    Collins, E.J.6    Frelinger, J.A.7    Robinson, B.W.8
  • 145
    • 77952549994 scopus 로고    scopus 로고
    • Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice
    • Pfannenstiel L.W., Lam S.S., Emens L.A., Jaffee E.M., Armstrong T.D. Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice. Cell. Immunol. 2010, 263:79-87.
    • (2010) Cell. Immunol. , vol.263 , pp. 79-87
    • Pfannenstiel, L.W.1    Lam, S.S.2    Emens, L.A.3    Jaffee, E.M.4    Armstrong, T.D.5
  • 146
    • 78650625238 scopus 로고    scopus 로고
    • Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
    • SPIRIT Investigators, France Intergroupe des Leucémies Myéloïdes Chroniques (Fi-LMC)France Intergroupe des Leucémies Myéloïdes Chroniques (Fi-LMC)
    • Preudhomme C., Guilhot J., Nicolini F.E., Guerci-Bresler A., Rigal-Huguet F., Maloisel F., Coiteux V., Gardembas M., Berthou C., Vekhoff A., et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N. Engl. J. Med. 2010, 363:2511-2521. SPIRIT Investigators, France Intergroupe des Leucémies Myéloïdes Chroniques (Fi-LMC)France Intergroupe des Leucémies Myéloïdes Chroniques (Fi-LMC).
    • (2010) N. Engl. J. Med. , vol.363 , pp. 2511-2521
    • Preudhomme, C.1    Guilhot, J.2    Nicolini, F.E.3    Guerci-Bresler, A.4    Rigal-Huguet, F.5    Maloisel, F.6    Coiteux, V.7    Gardembas, M.8    Berthou, C.9    Vekhoff, A.10
  • 148
    • 84871532643 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial
    • Reck M., Bondarenko I., Luft A., Serwatowski P., Barlesi F., Chacko R., Sebastian M., Lu H., Cuillerot J.M., Lynch T.J. Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial. Ann. Oncol. 2013, 24:75-83.
    • (2013) Ann. Oncol. , vol.24 , pp. 75-83
    • Reck, M.1    Bondarenko, I.2    Luft, A.3    Serwatowski, P.4    Barlesi, F.5    Chacko, R.6    Sebastian, M.7    Lu, H.8    Cuillerot, J.M.9    Lynch, T.J.10
  • 150
    • 84891625744 scopus 로고    scopus 로고
    • Long-term molecular remission with persistence of BCR-ABL1-specific cytotoxic T cells following imatinib withdrawal in an elderly patient with Philadelphia-positive ALL
    • Riva G., Luppi M., Lagreca I., Barozzi P., Quadrelli C., Vallerini D., Zanetti E., Basso S., Forghieri F., Morselli M., et al. Long-term molecular remission with persistence of BCR-ABL1-specific cytotoxic T cells following imatinib withdrawal in an elderly patient with Philadelphia-positive ALL. Br. J. Haematol. 2014, 164:299-302.
    • (2014) Br. J. Haematol. , vol.164 , pp. 299-302
    • Riva, G.1    Luppi, M.2    Lagreca, I.3    Barozzi, P.4    Quadrelli, C.5    Vallerini, D.6    Zanetti, E.7    Basso, S.8    Forghieri, F.9    Morselli, M.10
  • 153
    • 84920962202 scopus 로고    scopus 로고
    • Molecular and genetic properties of tumors associated with local immune cytolytic activity
    • Rooney M.S., Shukla S.A., Wu C.J., Getz G., Hacohen N. Molecular and genetic properties of tumors associated with local immune cytolytic activity. Cell 2015, 160:48-61.
    • (2015) Cell , vol.160 , pp. 48-61
    • Rooney, M.S.1    Shukla, S.A.2    Wu, C.J.3    Getz, G.4    Hacohen, N.5
  • 155
    • 84896754346 scopus 로고    scopus 로고
    • Lymphatic vessels and tertiary lymphoid organs
    • Ruddle N.H. Lymphatic vessels and tertiary lymphoid organs. J. Clin. Invest. 2014, 124:953-959.
    • (2014) J. Clin. Invest. , vol.124 , pp. 953-959
    • Ruddle, N.H.1
  • 159
    • 84926170848 scopus 로고    scopus 로고
    • Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma
    • Sagiv-Barfi I., Kohrt H.E., Burckhardt L., Czerwinski D.K., Levy R. Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma. Blood 2015, 125:2079-2086.
    • (2015) Blood , vol.125 , pp. 2079-2086
    • Sagiv-Barfi, I.1    Kohrt, H.E.2    Burckhardt, L.3    Czerwinski, D.K.4    Levy, R.5
  • 160
    • 84930486567 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition by erlotinib prevents vascular smooth muscle cell and monocyte-macrophage function in vitro
    • Savikko J., Rintala J.M., Rintala S., Koskinen P. Epidermal growth factor receptor inhibition by erlotinib prevents vascular smooth muscle cell and monocyte-macrophage function in vitro. Transpl. Immunol. 2015, 32:175-178.
    • (2015) Transpl. Immunol. , vol.32 , pp. 175-178
    • Savikko, J.1    Rintala, J.M.2    Rintala, S.3    Koskinen, P.4
  • 163
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber R.D., Old L.J., Smyth M.J. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011, 331:1565-1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 167
    • 84874232680 scopus 로고    scopus 로고
    • Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model
    • Sevko A., Michels T., Vrohlings M., Umansky L., Beckhove P., Kato M., Shurin G.V., Shurin M.R., Umansky V. Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model. J. Immunol. 2013, 190:2464-2471.
    • (2013) J. Immunol. , vol.190 , pp. 2464-2471
    • Sevko, A.1    Michels, T.2    Vrohlings, M.3    Umansky, L.4    Beckhove, P.5    Kato, M.6    Shurin, G.V.7    Shurin, M.R.8    Umansky, V.9
  • 169
    • 84930705241 scopus 로고    scopus 로고
    • Paradigm shift in oncology: targeting the immune system rather than cancer cells
    • Shekarian T., Valsesia-Wittmann S., Caux C., Marabelle A. Paradigm shift in oncology: targeting the immune system rather than cancer cells. Mutagenesis 2015, 30:205-211.
    • (2015) Mutagenesis , vol.30 , pp. 205-211
    • Shekarian, T.1    Valsesia-Wittmann, S.2    Caux, C.3    Marabelle, A.4
  • 171
    • 84883050177 scopus 로고    scopus 로고
    • Effect of initial treatment strategy on survival of patients with advanced-stage Hodgkin's lymphoma: a systematic review and network meta-analysis
    • Skoetz N., Trelle S., Rancea M., Haverkamp H., Diehl V., Engert A., Borchmann P. Effect of initial treatment strategy on survival of patients with advanced-stage Hodgkin's lymphoma: a systematic review and network meta-analysis. Lancet Oncol. 2013, 14:943-952.
    • (2013) Lancet Oncol. , vol.14 , pp. 943-952
    • Skoetz, N.1    Trelle, S.2    Rancea, M.3    Haverkamp, H.4    Diehl, V.5    Engert, A.6    Borchmann, P.7
  • 173
    • 34548785473 scopus 로고    scopus 로고
    • Non-oncogene addiction and the stress phenotype of cancer cells
    • Solimini N.L., Luo J., Elledge S.J. Non-oncogene addiction and the stress phenotype of cancer cells. Cell 2007, 130:986-988.
    • (2007) Cell , vol.130 , pp. 986-988
    • Solimini, N.L.1    Luo, J.2    Elledge, S.J.3
  • 174
    • 34249650184 scopus 로고    scopus 로고
    • Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
    • Spisek R., Charalambous A., Mazumder A., Vesole D.H., Jagannath S., Dhodapkar M.V. Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications. Blood 2007, 109:4839-4845.
    • (2007) Blood , vol.109 , pp. 4839-4845
    • Spisek, R.1    Charalambous, A.2    Mazumder, A.3    Vesole, D.H.4    Jagannath, S.5    Dhodapkar, M.V.6
  • 177
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman R.M., Banchereau J. Taking dendritic cells into medicine. Nature 2007, 449:419-426.
    • (2007) Nature , vol.449 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 178
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki E., Kapoor V., Jassar A.S., Kaiser L.R., Albelda S.M. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 2005, 11:6713-6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 182
    • 84892798051 scopus 로고    scopus 로고
    • Lymphocytic infiltrate is associated with favorable biomarkers profile in HER2-overexpressing breast cancers and adverse biomarker profile in ER-positive breast cancers
    • Tsang J.Y., Hui S.W., Ni Y.B., Chan S.K., Yamaguchi R., Kwong A., Law B.K., Tse G.M. Lymphocytic infiltrate is associated with favorable biomarkers profile in HER2-overexpressing breast cancers and adverse biomarker profile in ER-positive breast cancers. Breast Cancer Res. Treat. 2014, 143:1-9.
    • (2014) Breast Cancer Res. Treat. , vol.143 , pp. 1-9
    • Tsang, J.Y.1    Hui, S.W.2    Ni, Y.B.3    Chan, S.K.4    Yamaguchi, R.5    Kwong, A.6    Law, B.K.7    Tse, G.M.8
  • 185
    • 84873416598 scopus 로고    scopus 로고
    • Change in HER2 (ERBB2) gene status after taxane-based chemotherapy for breast cancer: polyploidization can lead to diagnostic pitfalls with potential impact for clinical management
    • Valent A., Penault-Llorca F., Cayre A., Kroemer G. Change in HER2 (ERBB2) gene status after taxane-based chemotherapy for breast cancer: polyploidization can lead to diagnostic pitfalls with potential impact for clinical management. Cancer Genet. 2013, 206:37-41.
    • (2013) Cancer Genet. , vol.206 , pp. 37-41
    • Valent, A.1    Penault-Llorca, F.2    Cayre, A.3    Kroemer, G.4
  • 191
  • 193
    • 80052692611 scopus 로고    scopus 로고
    • Association of intra-tumoral infiltrating macrophages and regulatory T cells is an independent prognostic factor in gastric cancer after radical resection
    • Wang B., Xu D., Yu X., Ding T., Rao H., Zhan Y., Zheng L., Li L. Association of intra-tumoral infiltrating macrophages and regulatory T cells is an independent prognostic factor in gastric cancer after radical resection. Ann. Surg. Oncol. 2011, 18:2585-2593.
    • (2011) Ann. Surg. Oncol. , vol.18 , pp. 2585-2593
    • Wang, B.1    Xu, D.2    Yu, X.3    Ding, T.4    Rao, H.5    Zhan, Y.6    Zheng, L.7    Li, L.8
  • 194
    • 84865793850 scopus 로고    scopus 로고
    • Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer
    • Wang Q., Li S.H., Wang H., Xiao Y., Sahin O., Brady S.W., Li P., Ge H., Jaffee E.M., Muller W.J., et al. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res. 2012, 72:4417-4428.
    • (2012) Cancer Res. , vol.72 , pp. 4417-4428
    • Wang, Q.1    Li, S.H.2    Wang, H.3    Xiao, Y.4    Sahin, O.5    Brady, S.W.6    Li, P.7    Ge, H.8    Jaffee, E.M.9    Muller, W.J.10
  • 196
    • 84899561523 scopus 로고    scopus 로고
    • Foxp3+ T cells inhibit antitumor immune memory modulated by mTOR inhibition
    • Wang Y., Sparwasser T., Figlin R., Kim H.L. Foxp3+ T cells inhibit antitumor immune memory modulated by mTOR inhibition. Cancer Res. 2014, 74:2217-2228.
    • (2014) Cancer Res. , vol.74 , pp. 2217-2228
    • Wang, Y.1    Sparwasser, T.2    Figlin, R.3    Kim, H.L.4
  • 197
    • 84896705997 scopus 로고    scopus 로고
    • Cancer Systems Biology: a peek into the future of patient care?
    • Werner H.M., Mills G.B., Ram P.T. Cancer Systems Biology: a peek into the future of patient care?. Nat. Rev. Clin. Oncol. 2014, 11:167-176.
    • (2014) Nat. Rev. Clin. Oncol. , vol.11 , pp. 167-176
    • Werner, H.M.1    Mills, G.B.2    Ram, P.T.3
  • 199
    • 84891373595 scopus 로고    scopus 로고
    • Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial
    • Westin J.R., Chu F., Zhang M., Fayad L.E., Kwak L.W., Fowler N., Romaguera J., Hagemeister F., Fanale M., Samaniego F., et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014, 15:69-77.
    • (2014) Lancet Oncol. , vol.15 , pp. 69-77
    • Westin, J.R.1    Chu, F.2    Zhang, M.3    Fayad, L.E.4    Kwak, L.W.5    Fowler, N.6    Romaguera, J.7    Hagemeister, F.8    Fanale, M.9    Samaniego, F.10
  • 200
    • 84891887628 scopus 로고    scopus 로고
    • Cause and consequence of cancer/testis antigen activation in cancer
    • Whitehurst A.W. Cause and consequence of cancer/testis antigen activation in cancer. Annu. Rev. Pharmacol. Toxicol. 2014, 54:251-272.
    • (2014) Annu. Rev. Pharmacol. Toxicol. , vol.54 , pp. 251-272
    • Whitehurst, A.W.1
  • 202
    • 84929632877 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8(+) T-cell responses and immune memory
    • Wu J., Waxman D.J. Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8(+) T-cell responses and immune memory. OncoImmunology 2015, 4:e1005521.
    • (2015) OncoImmunology , vol.4
    • Wu, J.1    Waxman, D.J.2
  • 204
    • 79956204623 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression
    • Xu X., Rao G.S., Groh V., Spies T., Gattuso P., Kaufman H.L., Plate J., Prinz R.A. Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression. BMC Cancer 2011, 11:194.
    • (2011) BMC Cancer , vol.11 , pp. 194
    • Xu, X.1    Rao, G.S.2    Groh, V.3    Spies, T.4    Gattuso, P.5    Kaufman, H.L.6    Plate, J.7    Prinz, R.A.8
  • 206
    • 84881192927 scopus 로고    scopus 로고
    • MTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function
    • Zeng H., Yang K., Cloer C., Neale G., Vogel P., Chi H. mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function. Nature 2013, 499:485-490.
    • (2013) Nature , vol.499 , pp. 485-490
    • Zeng, H.1    Yang, K.2    Cloer, C.3    Neale, G.4    Vogel, P.5    Chi, H.6
  • 207
    • 84941358268 scopus 로고    scopus 로고
    • Progression of Large Lymphoma Is Significantly Impeded with a Combination of Gemcitabine Chemotherapy and Dendritic Cells Intra-Tumor Vaccination
    • Zhu X.J., Yang Z.F., Zhou J.Y., Liu L., Sun X.M., Fan Z.F., Hu S.Y., Chen Y.C., Li W.X., Cao M., Wang L.X. Progression of Large Lymphoma Is Significantly Impeded with a Combination of Gemcitabine Chemotherapy and Dendritic Cells Intra-Tumor Vaccination. PLoS ONE 2015, 10:e0132799.
    • (2015) PLoS ONE , vol.10
    • Zhu, X.J.1    Yang, Z.F.2    Zhou, J.Y.3    Liu, L.4    Sun, X.M.5    Fan, Z.F.6    Hu, S.Y.7    Chen, Y.C.8    Li, W.X.9    Cao, M.10    Wang, L.X.11
  • 208
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • Zitvogel L., Tesniere A., Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. Immunol. 2006, 6:715-727.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 209
    • 84880747672 scopus 로고    scopus 로고
    • Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
    • Zitvogel L., Galluzzi L., Smyth M.J., Kroemer G. Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity 2013, 39:74-88.
    • (2013) Immunity , vol.39 , pp. 74-88
    • Zitvogel, L.1    Galluzzi, L.2    Smyth, M.J.3    Kroemer, G.4


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