메뉴 건너뛰기




Volumn 99, Issue 1, 2014, Pages 41-52

Relative increase in lymphocytes from as early as 1 month predicts improved response to dasatinib in chronic-phase chronic myelogenous leukemia

(18)  Kumagai, Takashi a   Matsuki, Eri b   Inokuchi, Koiti c   Ohashi, Kazuteru d   Shinagawa, Atsushi e   Takeuchi, Jin f   Yoshida, Chikashi g   Okamoto, Shinichiro b   Wakita, Hisashi h   Kozai, Yasuji i   Shirasugi, Yukari j   Fujisawa, Shin k   Iwase, Osamu l   Yano, Shingo m   Nishiwaki, Kaichi n   Oba, Koji o   Sakamoto, Junichi p   Sakamaki, Hisashi d  

e Hitachi   (Japan)

Author keywords

CML; Dasatinib; Lymphocytosis

Indexed keywords

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; FEMALE; FUSION PROTEINS, BCR-ABL; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, MYELOID, CHRONIC-PHASE; LYMPHOCYTE COUNT; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; NEOPLASM STAGING; PHENOTYPE; PROGNOSIS; PROTEIN KINASE INHIBITORS; PYRIMIDINES; THIAZOLES; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84899098640     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-013-1483-9     Document Type: Article
Times cited : (21)

References (41)
  • 2
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 1990;247:1079-82.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 5
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood. 2008;112:4808-17.
    • (2008) Blood , vol.112 , pp. 4808-4817
    • Druker, B.J.1
  • 8
    • 73349122639 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: An update of concepts and management recommendations of European leukemia net
    • Baccarani M, Cortes J, Pane F, Niederwieser D, Saglio G, Apperley J, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European leukemia net. J Clin Oncol. 2009;27:6041-51.
    • (2009) J Clin Oncol , vol.27 , pp. 6041-6051
    • Baccarani, M.1    Cortes, J.2    Pane, F.3    Niederwieser, D.4    Saglio, G.5    Apperley, J.6
  • 9
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • Kantarjian H, Shah NP, Hochhaus A, Cortes J, Shah S, Ayala M, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362:2260-70.
    • (2010) N Engl J Med , vol.362 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3    Cortes, J.4    Shah, S.5    Ayala, M.6
  • 10
    • 77953691179 scopus 로고    scopus 로고
    • Nilotinib versus imatinib for-newly diagnosed chronic myeloid leukemia
    • ENESTnd Investigators
    • Saglio G, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Lobo C, ENESTnd Investigators, et al. Nilotinib versus imatinib for-newly diagnosed chronic myeloid leukemia. N Engl J Med. 2010;362:2251-9.
    • (2010) N Engl J Med , vol.362 , pp. 2251-2259
    • Saglio, G.1    Kim, D.W.2    Issaragrisil, S.3    Le Coutre, P.4    Etienne, G.5    Lobo, C.6
  • 12
    • 0031014094 scopus 로고    scopus 로고
    • Platelets and inflammation: Role of platelet-derived growth factor, adhesion molecules and histamine
    • DOI 10.1007/PL00000158
    • Mannaioni PF, Di Bello MG, Masini E. Platelets and inflammation: role of platelet-derived growth factor, adhesion molecules and histamine. Inflamm Res. 1997;46:4-18. (Pubitemid 27068295)
    • (1997) Inflammation Research , vol.46 , Issue.1 , pp. 4-18
    • Mannaioni, P.F.1    Di, B.M.G.2    Masini, E.3
  • 13
    • 25444525158 scopus 로고    scopus 로고
    • Effects of imatinib on normal hematopoiesis and immune activation
    • DOI 10.1634/stemcells.2005-0069
    • Appel S, Balabanov S, Brümmendorf TH, Brossart P. Effects of imatinib on normal hematopoiesis and immune activation. Stem Cells. 2005;23:1082-8. (Pubitemid 41377724)
    • (2005) Stem Cells , vol.23 , Issue.8 , pp. 1082-1088
    • Appel, S.1    Balabanov, S.2    Brummendorf, T.H.3    Brossart, P.4
  • 14
    • 53749086585 scopus 로고    scopus 로고
    • Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling
    • Chen J, Schmitt A, Chen B, Rojewski M, Rübeler V, Fei F, et al. Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling. J Cell Mol Med. 2008;12(5B):2107-18.
    • (2008) J Cell Mol Med , vol.12 , Issue.5 , pp. 2107-2118
    • Chen, J.1    Schmitt, A.2    Chen, B.3    Rojewski, M.4    Rübeler, V.5    Fei, F.6
  • 15
    • 38949210227 scopus 로고    scopus 로고
    • Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation
    • DOI 10.1182/blood-2007-04-084814
    • Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R, et al. Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. Blood. 2008;111:1366-77. (Pubitemid 351213423)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1366-1377
    • Schade, A.E.1    Schieven, G.L.2    Townsend, R.3    Jankowska, A.M.4    Susulic, V.5    Zhang, R.6    Szpurka, H.7    Maciejewski, J.P.8
  • 17
    • 58149181387 scopus 로고    scopus 로고
    • Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo
    • Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R, et al. Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Exp Hematol. 2009;37:256-65.
    • (2009) Exp Hematol , vol.37 , pp. 256-265
    • Schade, A.E.1    Schieven, G.L.2    Townsend, R.3    Jankowska, A.M.4    Susulic, V.5    Zhang, R.6
  • 18
    • 75649105405 scopus 로고    scopus 로고
    • Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion
    • Porkka K, Khoury HJ, Paquette RL, Matloub Y, Sinha R, Cortes JE. Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion. Cancer. 2010;116:377-86.
    • (2010) Cancer , vol.116 , pp. 377-386
    • Porkka, K.1    Khoury, H.J.2    Paquette, R.L.3    Matloub, Y.4    Sinha, R.5    Cortes, J.E.6
  • 19
    • 77956280601 scopus 로고    scopus 로고
    • Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy
    • Kreutzman A, Juvonen V, Kairisto V, Ekblom M, Stenke L, Seggewiss R, et al. Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy. Blood. 2010;116:772-82.
    • (2010) Blood , vol.116 , pp. 772-782
    • Kreutzman, A.1    Juvonen, V.2    Kairisto, V.3    Ekblom, M.4    Stenke, L.5    Seggewiss, R.6
  • 20
    • 77954536015 scopus 로고    scopus 로고
    • Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion
    • Nagata Y, Ohashi K, Fukuda S, Kamata N, Akiyama H, Sakamaki H. Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion. Int J Hematol. 2010;91:799-807.
    • (2010) Int J Hematol , vol.91 , pp. 799-807
    • Nagata, Y.1    Ohashi, K.2    Fukuda, S.3    Kamata, N.4    Akiyama, H.5    Sakamaki, H.6
  • 22
    • 58149267985 scopus 로고    scopus 로고
    • Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
    • Kim DH, Kamel-Reid S, Chang H, Sutherland R, Jung CW, Kim HJ, et al. Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia. Haematologica. 2009;94:135-9.
    • (2009) Haematologica , vol.94 , pp. 135-139
    • Kim, D.H.1    Kamel-Reid, S.2    Chang, H.3    Sutherland, R.4    Jung, C.W.5    Kim, H.J.6
  • 23
    • 78650171874 scopus 로고    scopus 로고
    • Prevalence of large granular lymphocytosis in patients with chronic myelogenous leukemia (CML) treated with dasatinib
    • Valent JN, Schiffer CA. Prevalence of large granular lymphocytosis in patients with chronic myelogenous leukemia (CML) treated with dasatinib. Leuk Res. 2011;35:e1-3.
    • (2011) Leuk Res , vol.35
    • Valent, J.N.1    Schiffer, C.A.2
  • 24
    • 79953051767 scopus 로고    scopus 로고
    • Retrospective multicenter study on the development of peripheral lymphocytosis following secondline dasatinib therapy for chronic myeloid leukemia
    • Lee SJ, Jung CW, Kim DY, Lee KH, Sohn SK, Kwak JY, Kim HJ, Kim IH, Park S, Kim DH. Retrospective multicenter study on the development of peripheral lymphocytosis following secondline dasatinib therapy for chronic myeloid leukemia. Am J Hematol. 2011;86:346-50.
    • (2011) Am J Hematol , vol.86 , pp. 346-350
    • Lee, S.J.1    Jung, C.W.2    Kim, D.Y.3    Lee, K.H.4    Sohn, S.K.5    Kwak, J.Y.6    Kim, H.J.7    Kim, I.H.8    Park, S.9    Kim, D.H.10
  • 25
    • 84899087674 scopus 로고    scopus 로고
    • Association of lymphocytosis following treatment with dasatinib with response and outcome
    • (abstract). Abstract 6553
    • Mustjoki S, Ekblom M, Arstila TP, Dybedal I, Epling-Burnette PK, et al. Association of lymphocytosis following treatment with dasatinib with response and outcome (abstract). J Clin Oncol. 2010;28(15s):Abstract 6553.
    • (2010) J Clin Oncol , vol.28 , Issue.15
    • Mustjoki, S.1    Ekblom, M.2    Arstila, T.P.3    Dybedal, I.4    Epling-Burnette, P.K.5
  • 26
    • 74149095067 scopus 로고    scopus 로고
    • Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib: Weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history
    • Jabbour E, Hochhaus A, Cortes J, La Rosée P, Kantarjian HM. Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib: weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history. Leukemia. 2010;24:6-12.
    • (2010) Leukemia , vol.24 , pp. 6-12
    • Jabbour, E.1    Hochhaus, A.2    Cortes, J.3    La Rosée, P.4    Kantarjian, H.M.5
  • 27
    • 84880700401 scopus 로고    scopus 로고
    • Harmonization of molecular monitoring of chronic myeloid leukemia therapy in Japan
    • Yoshida C, Fletcher L, Ohashi K, Wakita H, Kumagai T, Shiseki M, et al. Harmonization of molecular monitoring of chronic myeloid leukemia therapy in Japan. Int J Clin Oncol. 2012;17(6):584-9.
    • (2012) Int J Clin Oncol , vol.17 , Issue.6 , pp. 584-589
    • Yoshida, C.1    Fletcher, L.2    Ohashi, K.3    Wakita, H.4    Kumagai, T.5    Shiseki, M.6
  • 28
    • 33645056193 scopus 로고    scopus 로고
    • Large granular lymphocyte leukemia
    • Sokol L, Loughran TP Jr. Large granular lymphocyte leukemia. Oncologist. 2006;11:263-73.
    • (2006) Oncologist , vol.11 , pp. 263-273
    • Sokol, L.1    Loughran Jr., T.P.2
  • 29
    • 84899120697 scopus 로고    scopus 로고
    • Dasatinib and imatinib-induced reductions in BCR-ABL transcript levels ≤10% at 3 months are associated with improved responses in patients with newly diagnosed CML-CP: Analysis of molecular response kinetics in the DASISION Trial
    • (abstract). Abstract 2767
    • A Hochhaus, G Saglio, C Chuah, C Pavlovsky, MB Bradley-Garelik, A Lambert et al. Dasatinib and imatinib-induced reductions in BCR-ABL transcript levels ≤10% at 3 months are associated with improved responses in patients with newly diagnosed CML-CP: analysis of molecular response kinetics in the DASISION Trial (abstract). Ann Meet Am Soc Hematol. 2011;Abstract 2767.
    • (2011) Ann Meet Am Soc Hematol
    • Hochhaus, A.1    Saglio, G.2    Chuah, C.3    Pavlovsky, C.4    Bradley-Garelik, M.B.5    Lambert, A.6
  • 30
    • 84865864744 scopus 로고    scopus 로고
    • Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
    • Hanfstein B, Müller MC, Hehlmann R, Erben P, Lauseker M, Fabarius A, et al. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia. 2012;26:2096-102.
    • (2012) Leukemia , vol.26 , pp. 2096-2102
    • Hanfstein, B.1    Müller, M.C.2    Hehlmann, R.3    Erben, P.4    Lauseker, M.5    Fabarius, A.6
  • 31
    • 84862907694 scopus 로고    scopus 로고
    • Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
    • Marin D, Ibrahim AR, Lucas C, Gerrard G, Wang L, Szydlo RM, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol. 2012;30:232-8.
    • (2012) J Clin Oncol , vol.30 , pp. 232-238
    • Marin, D.1    Ibrahim, A.R.2    Lucas, C.3    Gerrard, G.4    Wang, L.5    Szydlo, R.M.6
  • 32
    • 51649130092 scopus 로고    scopus 로고
    • The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes
    • Veldurthy A, Patz M, Hagist S, Pallasch CP, Wendtner CM, Hallek M, et al. The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes. Blood. 2008;112:1443-52.
    • (2008) Blood , vol.112 , pp. 1443-1452
    • Veldurthy, A.1    Patz, M.2    Hagist, S.3    Pallasch, C.P.4    Wendtner, C.M.5    Hallek, M.6
  • 33
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Réa D, Guilhot J, Guilhot F, Huguet F, Nicolini F, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11:1029-35.
    • (2010) Lancet Oncol , vol.11 , pp. 1029-1035
    • Mahon, F.X.1    Réa, D.2    Guilhot, J.3    Guilhot, F.4    Huguet, F.5    Nicolini, F.6
  • 34
    • 84862136806 scopus 로고    scopus 로고
    • Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia
    • Takahashi N, Kyo T, Maeda Y, Sugihara T, Usuki K, Kawaguchi T, et al. Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia. Haematologica. 2012;97:903-6.
    • (2012) Haematologica , vol.97 , pp. 903-906
    • Takahashi, N.1    Kyo, T.2    Maeda, Y.3    Sugihara, T.4    Usuki, K.5    Kawaguchi, T.6
  • 35
    • 84867023568 scopus 로고    scopus 로고
    • Rapid and sustained increase of large granular lymphocytes and rare cytomegalovirus reactivation during dasatinib treatment in chronic myelogenous leukemia patients
    • Tanaka H, Nakashima S, Usuda M. Rapid and sustained increase of large granular lymphocytes and rare cytomegalovirus reactivation during dasatinib treatment in chronic myelogenous leukemia patients. Int J Hematol. 2012;96:308-19.
    • (2012) Int J Hematol , vol.96 , pp. 308-319
    • Tanaka, H.1    Nakashima, S.2    Usuda, M.3
  • 37
    • 84899067325 scopus 로고    scopus 로고
    • November
    • Bristol-Myers Squibb. Pharmacokinetics, study CA180-031. (http://www.bms.co.jp/medical/sprycel/11.html). November, 2012.
    • (2012) Pharmacokinetics, Study CA180-031
  • 38
    • 80054026109 scopus 로고    scopus 로고
    • Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation
    • Kreutzman A, Ladell K, Koechel C, Gostick E, Ekblom M, Stenke L, et al. Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia. 2011;25:1587-97.
    • (2011) Leukemia , vol.25 , pp. 1587-1597
    • Kreutzman, A.1    Ladell, K.2    Koechel, C.3    Gostick, E.4    Ekblom, M.5    Stenke, L.6
  • 39
    • 79953206281 scopus 로고    scopus 로고
    • A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors
    • Powers JJ, Dubovsky JA, Epling-Burnette PK, Moscinski L, Zhang L, Mustjoki S, et al. A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors. Leuk Lymphoma. 2011;52:668-79.
    • (2011) Leuk Lymphoma , vol.52 , pp. 668-679
    • Powers, J.J.1    Dubovsky, J.A.2    Epling-Burnette, P.K.3    Moscinski, L.4    Zhang, L.5    Mustjoki, S.6
  • 40
    • 0029984379 scopus 로고    scopus 로고
    • Autologous activated natural killer cells suppress primitive chronic myelogenous leukemia progenitors in long-term culture
    • Cervantes F, Pierson BA, McGlave PB, Verfaillie CM, Miller JS. Autologous activated natural killer cells suppress primitive chronic myelogenous leukemia progenitors in long-term culture. Blood. 1996;87:2476-85. (Pubitemid 26086893)
    • (1996) Blood , vol.87 , Issue.6 , pp. 2476-2485
    • Cervantes, F.1    Pierson, B.A.2    McGlave, P.B.3    Verfaillie, C.M.4    Miller, J.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.