CD8-alpha T-cell infiltration in human papillomavirus-related oropharyngeal carcinoma correlates with improved patient prognosis

International Journal of Cancer

Volumn 132, Issue 2, 2013, Pages

  Jung, Alain C ^a   Guihard, Sébastien ^a   Krugell, Sylvie ^a   Ledrappier, Sonia ^a   Brochot, Alexandra ^b   Dalstein, Véronique ^b   Job, Sylvie ^c   De Reynies, Aurélien ^c   Noël, Georges ^a   Wasylyk, Bohdan ^d   Clavel, Christine ^b   Abecassis, Joseph ^a  

^a CENTRE PAUL STRAUSS   (France)

^b REIMS UNIVERSITY HOSPITAL   (France)

^c Programme Cartes d'Identite des Tumeurs CIT   (France)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

CD8 T cell; human papillomavirus; lymphocyte infiltration; oropharyngeal cancer; prognosis

Indexed keywords

ALPHA INTEGRIN; CD28 ANTIGEN; GRANZYME; GRANZYME K; RNA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CD3 ZETA GENE; CD4+ T LYMPHOCYTE; CD8 ALPHA GENE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE FREE SURVIVAL; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNE RESPONSE GENE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MALE; OROPHARYNX CANCER; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; STROMA; UPREGULATION; VIRUS CARCINOGENESIS; WART VIRUS;

ALPHAPAPILLOMAVIRUS; ANTIGENS, CD3; ANTIGENS, CD8; CARCINOMA, SQUAMOUS CELL; CD8-POSITIVE T-LYMPHOCYTES; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNITY, CELLULAR; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS, VIRAL; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRUS INFECTIONS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; TRANSCRIPTOME; TUMOR MICROENVIRONMENT;

EID: 84869507183     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27776     Document Type: Article

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