Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development

Biotechnology Progress

Volumn 31, Issue 6, 2015, Pages 1623-1632

  Janakiraman, Vijay ^a   Kwiatkowski, Chris ^a   Kshirsagar, Rashmi ^a   Ryll, Thomas ^a   Huang, Yao Ming ^a  

^a BIOGEN   (United States)

Author keywords

Control strategy; Mini bioreactors; Multivariate analysis; Process characterization; Scale down modeling

Indexed keywords

BIOCONVERSION; BIOREACTORS; CHARACTERIZATION; MANUFACTURE; MULTIVARIANT ANALYSIS; QUALITY CONTROL; THROUGHPUT;

BIO-PROCESSING INDUSTRIES; CONTROL STRATEGIES; HIGH THROUGHPUT SYSTEMS; MICROSCALE BIOREACTORS; MULTI VARIATE ANALYSIS; MULTIVARIATE ANALYSIS TECHNIQUES; PROCESS CHARACTERIZATION; SCALE DOWN MODEL;

PROCESS CONTROL;

ANIMAL; BIOLOGICAL MODEL; BIOREACTOR; CHO CELL LINE; CRICETULUS; HAMSTER; HIGH THROUGHPUT SCREENING; MINIATURIZATION; MULTIVARIATE ANALYSIS; PROCEDURES; TEMPERATURE;

ANIMALS; BIOREACTORS; CHO CELLS; CRICETINAE; CRICETULUS; HIGH-THROUGHPUT SCREENING ASSAYS; MINIATURIZATION; MODELS, BIOLOGICAL; MULTIVARIATE ANALYSIS; TEMPERATURE;

EID: 84956591677     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.2162     Document Type: Article

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