Automated disposable small scale reactor for high throughput bioprocess development: A proof of concept study

Biotechnology and Bioengineering

Volumn 110, Issue 12, 2013, Pages 3126-3138

  Bareither, Rachel ^a   Bargh, Neil ^b   Oakeshott, Robert ^b   Watts, Kathryn ^a   Pollard, David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b SARTORIUS STEDIM BIOTECH GMBH   (Germany)

Author keywords

Disposable reactor; High throughput; Process development

Indexed keywords

BIOPROCESS DEVELOPMENT; CHARACTERIZATION STUDIES; DISPOSABLE REACTOR; HIGH THROUGHPUT; HIGH THROUGHPUT PROCESS DEVELOPMENT; HIGH THROUGHPUT TECHNOLOGY; MONOCLONAL ANTIBODY PRODUCTION; PROCESS DEVELOPMENT;

CELL CULTURE; CLONE CELLS; ESCHERICHIA COLI; MONOCLONAL ANTIBODIES; QUALITY CONTROL; TECHNOLOGY; THROUGHPUT;

AUTOMATION;

MONOCLONAL ANTIBODY; PROTEIN;

ARTICLE; BACTERIAL CELL; BIOPROCESS; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; ESCHERICHIA COLI; NONHUMAN; PICHIA PASTORIS; PROCESS DEVELOPMENT; SMALL SCALE STIRRED BIOREACTOR; STIRRED REACTOR;

PICHIA PASTORIS;

DISPOSABLE REACTOR; HIGH THROUGHPUT; PROCESS DEVELOPMENT;

ANIMALS; AUTOMATION; BIOLOGICAL PRODUCTS; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETULUS; DISPOSABLE EQUIPMENT; ESCHERICHIA COLI; MICROBIOLOGICAL TECHNIQUES; PICHIA; TECHNOLOGY, PHARMACEUTICAL; VACCINES;

EID: 84886241053     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24978     Document Type: Article

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