메뉴 건너뛰기




Volumn 24, Issue 4, 2016, Pages 328-339

Immune-tolerant elastin-like polypeptides (iTEPs) and their application as CTL vaccine carriers

Author keywords

Cytotoxic T lymphocyte (CTL) vaccine; immune tolerant elastin like polypeptide; inverse phase transition; non canonical elastin like polypeptide motifs; reversible; thermally induced; vaccine carrier

Indexed keywords

CYTOTOXIC T LYMPHOCYTE VACCINE; ELASTIN LIKE POLYPEPTIDE; PEPTIDE VACCINE; POLYPEPTIDE; UNCLASSIFIED DRUG; VACCINE; DRUG CARRIER; ELASTIN; IMMUNOGLOBULIN G; NANOPARTICLE; PEPTIDE; RECOMBINANT VACCINE;

EID: 84956573779     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2015.1077847     Document Type: Article
Times cited : (35)

References (67)
  • 1
    • 17644419950 scopus 로고    scopus 로고
    • T cell vaccines for microbial infections
    • Robinson HL, Amara RR. T cell vaccines for microbial infections. Nat Med 2005;11:s25-32.
    • (2005) Nat Med , vol.11 , pp. s25-32
    • Robinson, H.L.1    Amara, R.R.2
  • 2
    • 80055087402 scopus 로고    scopus 로고
    • Live attenuated malaria vaccine designed to protect through hepatic CD8+ T cell immunity
    • Epstein JE, Tewari K, Lyke KE, et al. Live attenuated malaria vaccine designed to protect through hepatic CD8+ T cell immunity. Science 2011;334:475-80.
    • (2011) Science , vol.334 , pp. 475-480
    • Epstein, J.E.1    Tewari, K.2    Lyke, K.E.3
  • 4
    • 27744509733 scopus 로고    scopus 로고
    • Efficient induction of tumoricidal cytotoxic T lymphocytes by HLA-A0201 restricted, melanoma associated, L(27)Melan-A/MART-1(26-35) peptide encapsulated into virosomes in vitro
    • Schumacher R, Amacker M, Neuhaus D, et al. Efficient induction of tumoricidal cytotoxic T lymphocytes by HLA-A0201 restricted, melanoma associated, L(27)Melan-A/MART-1(26-35) peptide encapsulated into virosomes in vitro. Vaccine 2005;23: 5572-82.
    • (2005) Vaccine , vol.23 , pp. 5572-5582
    • Schumacher, R.1    Amacker, M.2    Neuhaus, D.3
  • 5
    • 79551699386 scopus 로고    scopus 로고
    • Viral nanoparticles and virus-like particles: Platforms for contemporary vaccine design
    • Plummer EM, Manchester M. Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design. WIREs Nanomed Nanobiotechnol 2011;3:174-96.
    • (2011) WIREs Nanomed Nanobiotechnol , vol.3 , pp. 174-196
    • Plummer, E.M.1    Manchester, M.2
  • 6
    • 84927161447 scopus 로고    scopus 로고
    • Immunoengineering: How nanotechnology can enhance cancer immunotherapy
    • Goldberg MS. Immunoengineering: how nanotechnology can enhance cancer immunotherapy. Cell 2015;161:201-4.
    • (2015) Cell , vol.161 , pp. 201-204
    • Goldberg, M.S.1
  • 7
    • 84931060402 scopus 로고    scopus 로고
    • Biomaterials for nanoparticle vaccine delivery systems
    • Sahdev P, Ochyl L, Moon J. Biomaterials for nanoparticle vaccine delivery systems. Pharm Res 2014;31:2563-82.
    • (2014) Pharm Res , vol.31 , pp. 2563-2582
    • Sahdev, P.1    Ochyl, L.2    Moon, J.3
  • 8
    • 40149112201 scopus 로고    scopus 로고
    • Temperature triggered self-assembly of polypeptides into multivalent spherical micelles
    • Dreher MR, Simnick AJ, Fischer K, et al. Temperature triggered self-assembly of polypeptides into multivalent spherical micelles. J Am Chem Soc 2008;130:687-94.
    • (2008) J Am Chem Soc , vol.130 , pp. 687-694
    • Dreher, M.R.1    Simnick, A.J.2    Fischer, K.3
  • 9
    • 84861136820 scopus 로고    scopus 로고
    • Unexpected multivalent display of proteins by temperature triggered selfassembly of elastin-like polypeptide block copolymers
    • Hassouneh W, Fischer K, MacEwan SR, et al. Unexpected multivalent display of proteins by temperature triggered selfassembly of elastin-like polypeptide block copolymers. Biomacromolecules 2012;13:1598-605.
    • (2012) Biomacromolecules , vol.13 , pp. 1598-1605
    • Hassouneh, W.1    Fischer, K.2    MacEwan, S.R.3
  • 10
    • 33645112928 scopus 로고    scopus 로고
    • Forcing single-chain variable fragment production in tobacco seeds by fusion to elastin-like polypeptides
    • Scheller J, Leps M, Conrad U. Forcing single-chain variable fragment production in tobacco seeds by fusion to elastin-like polypeptides. Plant Biotechnol J 2006;4:243-9.
    • (2006) Plant Biotechnol J , vol.4 , pp. 243-249
    • Scheller, J.1    Leps, M.2    Conrad, U.3
  • 11
    • 0037097764 scopus 로고    scopus 로고
    • A decaepitope polypeptide primes for multiple CD8+ IFN-gamma and Th lymphocyte responses: Evaluation of multiepitope polypeptides as a mode for vaccine delivery
    • Alexander J, Oseroff C, Dahlberg C, et al. A decaepitope polypeptide primes for multiple CD8+ IFN-gamma and Th lymphocyte responses: evaluation of multiepitope polypeptides as a mode for vaccine delivery. J Immunol 2002;168:6189-98.
    • (2002) J Immunol , vol.168 , pp. 6189-6198
    • Alexander, J.1    Oseroff, C.2    Dahlberg, C.3
  • 12
    • 0035860626 scopus 로고    scopus 로고
    • Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines
    • Livingston BD, Newman M, Crimi C, et al. Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines. Vaccine 2001;19:4652-60.
    • (2001) Vaccine , vol.19 , pp. 4652-4660
    • Livingston, B.D.1    Newman, M.2    Crimi, C.3
  • 13
    • 0028998731 scopus 로고
    • Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: Implications for vaccine design
    • Thomson SA, Khanna R, Gardner J, et al. Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: implications for vaccine design. Proc Natl Acad Sci USA 1995;92:5845-9.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5845-5849
    • Thomson, S.A.1    Khanna, R.2    Gardner, J.3
  • 14
    • 77956493179 scopus 로고    scopus 로고
    • Elastin-like polypeptides as a purification tag for recombinant proteins
    • Chapter 6: Unit 6 11
    • Hassouneh W, Christensen T, Chilkoti A. Elastin-like polypeptides as a purification tag for recombinant proteins. Curr Protoc Protein Sci 2010; Chapter 6: Unit 6 11.
    • (2010) Curr Protoc Protein Sci
    • Hassouneh, W.1    Christensen, T.2    Chilkoti, A.3
  • 15
    • 0035950924 scopus 로고    scopus 로고
    • Effect of preexisting neutralizing antibodies on the anti-tumor immune response induced by chimeric human papillomavirus virus-like particle vaccines
    • Da Silva DM, Pastrana DV, Schiller JT, Kast WM. Effect of preexisting neutralizing antibodies on the anti-tumor immune response induced by chimeric human papillomavirus virus-like particle vaccines. Virology 2001;290:350-60.
    • (2001) Virology , vol.290 , pp. 350-360
    • Da Silva, D.M.1    Pastrana, D.V.2    Schiller, J.T.3    Kast, W.M.4
  • 16
    • 11144221879 scopus 로고    scopus 로고
    • Virus-like particles as carriers for T-cell epitopes: Limited inhibition of T-cell priming by carrier-specific antibodies
    • Ruedl C, Schwarz K, Jegerlehner A, et al. Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies. J Virol 2005;79:717-24.
    • (2005) J Virol , vol.79 , pp. 717-724
    • Ruedl, C.1    Schwarz, K.2    Jegerlehner, A.3
  • 17
    • 0142179317 scopus 로고    scopus 로고
    • IL-10 mediates suppression of the CD8 T cell IFN-gamma response to a novel viral epitope in a primed host
    • Liu XS, Xu Y, Hardy L, et al. IL-10 mediates suppression of the CD8 T cell IFN-gamma response to a novel viral epitope in a primed host. J Immunol 2003;171:4765-72.
    • (2003) J Immunol , vol.171 , pp. 4765-4772
    • Liu, X.S.1    Xu, Y.2    Hardy, L.3
  • 18
    • 0026196257 scopus 로고
    • Biocompatibility of the bioelastic materials, poly(GVGVP) and its g-irradiation crosslinked matrix: Summary of generic biological test results
    • Urry DW, Parker TM, Reid MC, Gowda DC. Biocompatibility of the bioelastic materials, poly(GVGVP) and its g-irradiation crosslinked matrix: summary of generic biological test results. J Bioactive Compatible Polym 1991;6:263-82.
    • (1991) J Bioactive Compatible Polym , vol.6 , pp. 263-282
    • Urry, D.W.1    Parker, T.M.2    Reid, M.C.3    Gowda, D.C.4
  • 19
    • 0013611533 scopus 로고    scopus 로고
    • Transductional elastic and plastic protein-based polymers as potential medical devices
    • Domb AJ, Kost J, Wiseman DM, eds. Amsterdam, The Netherlands: CRC Press
    • Urry DW, Pattanaik A, Accavitti MA, et al. Transductional elastic and plastic protein-based polymers as potential medical devices. In: Domb AJ, Kost J, Wiseman DM, eds. Handbook of biodegradable polymers. Amsterdam, The Netherlands: CRC Press; 1998.
    • (1998) Handbook of Biodegradable Polymers
    • Urry, D.W.1    Pattanaik, A.2    Accavitti, M.A.3
  • 21
    • 0002919179 scopus 로고    scopus 로고
    • Genetically engineered protein polymers
    • Domb AJ, Kost J, Wiseman DM, eds. Amsterdam: Harwood Academic Publishers
    • Cappello J. Genetically engineered protein polymers. In: Domb AJ, Kost J, Wiseman DM, eds. Handbook of biodegradable polymers. Amsterdam: Harwood Academic Publishers; 1997:387-416.
    • (1997) Handbook of Biodegradable Polymers , pp. 387-416
    • Cappello, J.1
  • 22
    • 84938743997 scopus 로고    scopus 로고
    • Reducing the visibility of the vector/DNA nanocomplexes to the immune system by elastin-like peptides
    • Nouri F, Wang X, Chen X, Hatefi A. Reducing the visibility of the vector/DNA nanocomplexes to the immune system by elastin-Like peptides. Pharm Res 2015;32:3018-28.
    • (2015) Pharm Res , vol.32 , pp. 3018-3028
    • Nouri, F.1    Wang, X.2    Chen, X.3    Hatefi, A.4
  • 23
    • 84873381594 scopus 로고    scopus 로고
    • Immunomodulatory nanoparticles from elastin-like recombinamers: Single-molecules for tuberculosis vaccine development
    • Garcia-Arevalo C, Bermejo-Martin JF, Rico L, et al. Immunomodulatory nanoparticles from elastin-like recombinamers: single-molecules for tuberculosis vaccine development. Mol Pharm 2013;10:586-97.
    • (2013) Mol Pharm , vol.10 , pp. 586-597
    • Garcia-Arevalo, C.1    Bermejo-Martin, J.F.2    Rico, L.3
  • 24
    • 0034102538 scopus 로고    scopus 로고
    • Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis
    • Moreland LW, McCabe DP, Caldwell JR, et al. Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis. J Rheumatol 2000;27:601-9.
    • (2000) J Rheumatol , vol.27 , pp. 601-609
    • Moreland, L.W.1    McCabe, D.P.2    Caldwell, J.R.3
  • 25
    • 12444335752 scopus 로고    scopus 로고
    • Intravenous human recombinant tumor necrosis factor receptor p55-Fc IgG1 fusion protein Ro 45-2081 (lenercept): A double blind, placebo controlled dose-finding study in rheumatoid arthritis
    • Rau R, Sander O, van Riel P, et al. Intravenous human recombinant tumor necrosis factor receptor p55-Fc IgG1 fusion protein Ro 45-2081 (lenercept): a double blind, placebo controlled dose-finding study in rheumatoid arthritis. J Rheumatol 2003;30:680-90.
    • (2003) J Rheumatol , vol.30 , pp. 680-690
    • Rau, R.1    Sander, O.2    Van Riel, P.3
  • 26
    • 0026468684 scopus 로고
    • Free energy transduction in polypeptides and proteins based on inverse temperature transitions
    • Urry DW. Free energy transduction in polypeptides and proteins based on inverse temperature transitions. Prog Biophys Mol Biol 1992;57:23-57.
    • (1992) Prog Biophys Mol Biol , vol.57 , pp. 23-57
    • Urry, D.W.1
  • 27
    • 77950354591 scopus 로고    scopus 로고
    • Elastin-like polypeptides: Biomedical applications of tunable biopolymers
    • MacEwan SR, Chilkoti A. Elastin-like polypeptides: biomedical applications of tunable biopolymers. Pept Sci 2010;94:60-77.
    • (2010) Pept Sci , vol.94 , pp. 60-77
    • MacEwan, S.R.1    Chilkoti, A.2
  • 28
    • 77950793580 scopus 로고    scopus 로고
    • Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes
    • McDaniel JR, Mackay JA, Quiroz FG, Chilkoti A. Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes. Biomacromolecules 2010; 11:944-52.
    • (2010) Biomacromolecules , vol.11 , pp. 944-952
    • McDaniel, J.R.1    Mackay, J.A.2    Quiroz, F.G.3    Chilkoti, A.4
  • 29
    • 0027222867 scopus 로고
    • Peptide-priming of cytolytic T cell immunity in vivo using beta 2-microglobulin as an adjuvant
    • Rock KL, Fleischacker C, Gamble S. Peptide-priming of cytolytic T cell immunity in vivo using beta 2-microglobulin as an adjuvant. J Immunol 1993;150:1244-52.
    • (1993) J Immunol , vol.150 , pp. 1244-1252
    • Rock, K.L.1    Fleischacker, C.2    Gamble, S.3
  • 30
    • 84905459955 scopus 로고    scopus 로고
    • ITEP nanoparticle delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors
    • Zhao P, Dong S, Bhattacharyya J, Chen M. iTEP nanoparticle delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors. Mol Pharm 2014;11:2703-12.
    • (2014) Mol Pharm , vol.11 , pp. 2703-2712
    • Zhao, P.1    Dong, S.2    Bhattacharyya, J.3    Chen, M.4
  • 31
    • 0023511413 scopus 로고
    • Copper staining: A five-minute protein stain for sodium dodecyl sulfate-polyacrylamide gels
    • Lee C, Levin A, Branton D. Copper staining: a five-minute protein stain for sodium dodecyl sulfate-polyacrylamide gels. Anal Biochem 1987;166:308-12.
    • (1987) Anal Biochem , vol.166 , pp. 308-312
    • Lee, C.1    Levin, A.2    Branton, D.3
  • 32
    • 0032429160 scopus 로고    scopus 로고
    • A statistically defined endpoint titer determination method for immunoassays
    • Frey A, Di Canzio J, Zurakowski D. A statistically defined endpoint titer determination method for immunoassays. J Immunol Methods 1998;221:35-41.
    • (1998) J Immunol Methods , vol.221 , pp. 35-41
    • Frey, A.1    Di Canzio, J.2    Zurakowski, D.3
  • 33
    • 0031569109 scopus 로고    scopus 로고
    • Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules
    • Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol 1997;158:2723-30.
    • (1997) J Immunol , vol.158 , pp. 2723-2730
    • Shen, Z.1    Reznikoff, G.2    Dranoff, G.3    Rock, K.L.4
  • 34
    • 0026639652 scopus 로고
    • Detection of rare antigenpresenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens
    • Karttunen J, Sanderson S, Shastri N. Detection of rare antigenpresenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens. Proc Natl Acad Sci 1992;89:6020-4.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 6020-6024
    • Karttunen, J.1    Sanderson, S.2    Shastri, N.3
  • 36
    • 0027450354 scopus 로고
    • T cell-dependent B cell activation
    • Parker DC. T cell-dependent B cell activation. Annu Rev Immunol 1993;11:331-60.
    • (1993) Annu Rev Immunol , vol.11 , pp. 331-360
    • Parker, D.C.1
  • 38
    • 0001930144 scopus 로고
    • Molecular disection of protein antigens
    • Van Regenmortel MH, ed. Boca Raton (FL): CRC Press
    • Van Regenmortel MH. Molecular disection of protein antigens. In: Van Regenmortel MH, ed. Structure of antigens. Boca Raton (FL): CRC Press;1992:1-28.
    • (1992) Structure of Antigens , pp. 1-28
    • Van Regenmortel, M.H.1
  • 39
    • 0014673113 scopus 로고
    • Antigenicity: Some molecular aspects
    • Sela M. Antigenicity: some molecular aspects. Science 1969;166: 1365-74.
    • (1969) Science , vol.166 , pp. 1365-1374
    • Sela, M.1
  • 40
    • 84956596896 scopus 로고    scopus 로고
    • The development and survival of lymphocytes
    • London and New York: Garland Science
    • Murphy K. The development and survival of lymphocytes. in Janeway's Immunobiology. London and New York: Garland Science; 2012:275-333.
    • (2012) Janeway's Immunobiology , pp. 275-333
    • Murphy, K.1
  • 41
    • 7744239182 scopus 로고    scopus 로고
    • High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity
    • Liu W, Peng Z, Liu Z, et al. High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity. Vaccine 2004;23:366-71.
    • (2004) Vaccine , vol.23 , pp. 366-371
    • Liu, W.1    Peng, Z.2    Liu, Z.3
  • 42
    • 33750610963 scopus 로고    scopus 로고
    • Tandem copies of a human rotavirus VP8 epitope can induce specific neutralizing antibodies in BALB/c mice
    • Kovacs-Nolan J, Mine Y. Tandem copies of a human rotavirus VP8 epitope can induce specific neutralizing antibodies in BALB/c mice. Biochim Biophys Acta 2006;1760:1884-93.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1884-1893
    • Kovacs-Nolan, J.1    Mine, Y.2
  • 43
    • 0026788007 scopus 로고
    • The influence of orientation and number of copies of T and B cell epitopes on the specificity and affinity of antibodies induced by chimeric peptides
    • Partidos C, Stanley C, Steward M. The influence of orientation and number of copies of T and B cell epitopes on the specificity and affinity of antibodies induced by chimeric peptides. Eur J Immunol 1992;22:2675-80.
    • (1992) Eur J Immunol , vol.22 , pp. 2675-2680
    • Partidos, C.1    Stanley, C.2    Steward, M.3
  • 44
    • 49649091350 scopus 로고    scopus 로고
    • An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes
    • Onda M, Beers R, Xiang L, et al. An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes. Proc Natl Acad Sci USA 2008;105:11311-16.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11311-11316
    • Onda, M.1    Beers, R.2    Xiang, L.3
  • 45
    • 33845457606 scopus 로고    scopus 로고
    • Characterization of the B cell epitopes associated with a truncated form of pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients
    • Onda M, Nagata S, Fitz Gerald DJ, et al. Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients. J Immunol 2006;177:8822-34.
    • (2006) J Immunol , vol.177 , pp. 8822-8834
    • Onda, M.1    Nagata, S.2    Fitz Gerald, D.J.3
  • 46
    • 33644670965 scopus 로고    scopus 로고
    • The coomassie chronicles: Past, present and future perspectives in polyacrylamide gel staining
    • Smejkal GB. The coomassie chronicles: past, present and future perspectives in polyacrylamide gel staining. Expert Rev Proteomics 2004;1:381-7.
    • (2004) Expert Rev Proteomics , vol.1 , pp. 381-387
    • Smejkal, G.B.1
  • 48
    • 84984621304 scopus 로고
    • Temperature of polypeptide inverse temperature transition depends on mean residue hydrophobicity
    • Urry DW, Luan CH, Parker TM, et al. Temperature of polypeptide inverse temperature transition depends on mean residue hydrophobicity. J Am Chem Soc 1991;113:4346-8.
    • (1991) J Am Chem Soc , vol.113 , pp. 4346-4348
    • Urry, D.W.1    Luan, C.H.2    Parker, T.M.3
  • 49
    • 2542628131 scopus 로고    scopus 로고
    • Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides
    • Meyer DE, Chilkoti A. Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides. Biomacromolecules 2004;5:846-1.
    • (2004) Biomacromolecules , vol.5 , pp. 846-851
    • Meyer, D.E.1    Chilkoti, A.2
  • 50
    • 81255176906 scopus 로고    scopus 로고
    • Aggregation, immune complexes and immunogenicity
    • Jefferis R. Aggregation, immune complexes and immunogenicity. MABS 2011;3:503-4.
    • (2011) MABS , vol.3 , pp. 503-504
    • Jefferis, R.1
  • 51
    • 33748041958 scopus 로고    scopus 로고
    • Effects of protein aggregates: An immunologic perspective
    • Rosenberg AS. Effects of protein aggregates: an immunologic perspective. AAPS J 2006;8:E501-7.
    • (2006) AAPS J , vol.8 , pp. E501-E507
    • Rosenberg, A.S.1
  • 52
    • 84871949938 scopus 로고    scopus 로고
    • Stratification of antibody-positive subjects by antibody level reveals an impact of immunogenicity on pharmacokinetics
    • Zhou L, Hoofring S, Wu Y, et al. Stratification of antibody-positive subjects by antibody level reveals an impact of immunogenicity on pharmacokinetics. AAPS J 2013;15:30-40.
    • (2013) AAPS J , vol.15 , pp. 30-40
    • Zhou, L.1    Hoofring, S.2    Wu, Y.3
  • 53
    • 84858631195 scopus 로고    scopus 로고
    • Drug development: Longer-lived proteins
    • Kontos S, Hubbell JA. Drug development: longer-lived proteins. Chem Soc Rev 2012;41:2686-95.
    • (2012) Chem Soc Rev , vol.41 , pp. 2686-2695
    • Kontos, S.1    Hubbell, J.A.2
  • 54
    • 36049006592 scopus 로고    scopus 로고
    • Immunogenicity of protein therapeutics
    • De Groot AS, Scott DW. Immunogenicity of protein therapeutics. Trends Immunol 2007;28:482-90.
    • (2007) Trends Immunol , vol.28 , pp. 482-490
    • De Groot, A.S.1    Scott, D.W.2
  • 55
    • 84886530982 scopus 로고    scopus 로고
    • Silver Spring (MD): U.S. Department of Health and Human Services Food and Drug Administration
    • U.S. Department of Health and Human Services Food and Drug Administration, Guidance for industry immunogenicity assessment for therapeutic protein products. Silver Spring (MD): U.S. Department of Health and Human Services Food and Drug Administration; 2013.
    • (2013) Guidance for Industry Immunogenicity Assessment for Therapeutic Protein Products
  • 56
    • 33744950980 scopus 로고    scopus 로고
    • Scientific and regulatory considerations on the immunogenicity of biologics
    • Shankar G, Shores E, Wagner C, Mire-Sluis A. Scientific and regulatory considerations on the immunogenicity of biologics. Trends Biotechnol 2006;24:274-80.
    • (2006) Trends Biotechnol , vol.24 , pp. 274-280
    • Shankar, G.1    Shores, E.2    Wagner, C.3    Mire-Sluis, A.4
  • 58
    • 0015094677 scopus 로고
    • The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response
    • Feldmann M, Basten A. The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response. J Exp Med 1971;134:103-19.
    • (1971) J Exp Med , vol.134 , pp. 103-119
    • Feldmann, M.1    Basten, A.2
  • 59
    • 0038388786 scopus 로고    scopus 로고
    • Physical chemistry of biological free energy transductioin as demonstrated by elastic protein-based polymers
    • Urry DW. Physical chemistry of biological free energy transductioin as demonstrated by elastic protein-based polymers. J Phys Chem B 1997;101:11007-28.
    • (1997) J Phys Chem B , vol.101 , pp. 11007-11028
    • Urry, D.W.1
  • 61
    • 77953808232 scopus 로고    scopus 로고
    • Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model
    • Liu W, MacKay JA, Dreher MR, et al. Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model. J Control Release 2010;144: 2-9.
    • (2010) J Control Release , vol.144 , pp. 2-9
    • Liu, W.1    MacKay, J.A.2    Dreher, M.R.3
  • 62
    • 70549101139 scopus 로고    scopus 로고
    • Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection
    • MacKay JA, Chen M, McDaniel JR, et al. Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection. Nat Mater 2009;8: 993-9.
    • (2009) Nat Mater , vol.8 , pp. 993-999
    • MacKay, J.A.1    Chen, M.2    McDaniel, J.R.3
  • 63
    • 84892923466 scopus 로고    scopus 로고
    • Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo
    • Shi P, Aluri S, Lin YA, et al. Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo. J Control Release 2013;171:330-8.
    • (2013) J Control Release , vol.171 , pp. 330-338
    • Shi, P.1    Aluri, S.2    Lin, Y.A.3
  • 64
    • 84872872856 scopus 로고    scopus 로고
    • Thermally targeted delivery of a c-myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model
    • Bidwell 3rd GL, Perkins E, Hughes J, et al. Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model. PLoS One 2013;8: e55104.
    • (2013) PLoS One , vol.8 , pp. e55104
    • Bidwell, G.L.1    Perkins, E.2    Hughes, J.3
  • 65
    • 84883256420 scopus 로고    scopus 로고
    • Future directions for peptide therapeutics development
    • Kaspar AA, Reichert JM. Future directions for peptide therapeutics development. Drug Discov Today 2013;18:807-17.
    • (2013) Drug Discov Today , vol.18 , pp. 807-817
    • Kaspar, A.A.1    Reichert, J.M.2
  • 66
    • 84875975001 scopus 로고    scopus 로고
    • Self-assembly of elastinmimetic double hydrophobic polypeptides
    • Le DH, Hanamura R, Pham DH, et al. Self-assembly of elastinmimetic double hydrophobic polypeptides. Biomacromolecules 2013;14:1028-34.
    • (2013) Biomacromolecules , vol.14 , pp. 1028-1034
    • Le, D.H.1    Hanamura, R.2    Pham, D.H.3
  • 67
    • 84878733337 scopus 로고    scopus 로고
    • Sequence-specific crosslinking of electrospun, elastin-like protein preserves bioactivity and native-like mechanics
    • Benitez PL, Sweet JA, Fink H, et al. Sequence-specific crosslinking of electrospun, elastin-like protein preserves bioactivity and native-like mechanics. Adv Healthc Mater 2013;2: 114-18.
    • (2013) Adv Healthc Mater , vol.2 , pp. 114-118
    • Benitez, P.L.1    Sweet, J.A.2    Fink, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.