ITEP nanoparticle-delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors

Molecular Pharmaceutics

Volumn 11, Issue 8, 2014, Pages 2703-2712

  Zhao, Peng ^a   Dong, Shuyun ^a   Bhattacharyya, Jayanta ^b   Chen, Mingnan ^a  

^a UNIVERSITY OF UTAH   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

cancer stem cells; coencapsulation additives; iTEP nanoparticle; salinomycin; tumor multidrug resistance

Indexed keywords

ALPHA TOCOPHEROL; ELASTIN LIKE POLYPEPTIDE NANOPARTICLE; HEXYLAMINE; HEXYLDIMETHYLAMINE; NANOPARTICLE; SALINOMYCIN; UNCLASSIFIED DRUG; AMINE; DRUG CARRIER; ELASTIN; PYRAN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BREAST TUMOR; CANCER INHIBITION; CANCER STEM CELL; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PENETRATION; DRUG RELEASE; FEMALE; HYDROPHOBICITY; MOUSE; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR REGRESSION; TUMOR VOLUME; ANIMAL; BAGG ALBINO MOUSE; BREAST NEOPLASMS; CANCER TRANSPLANTATION; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; MULTIDRUG RESISTANCE; NANOMEDICINE; PROCEDURES; TIME; TISSUE DISTRIBUTION;

ALPHA-TOCOPHEROL; AMINES; ANIMALS; BREAST NEOPLASMS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ELASTIN; FEMALE; MICE; MICE, INBRED BALB C; NANOMEDICINE; NANOPARTICLES; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PYRANS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84905459955     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp5002312     Document Type: Article

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