Live attenuated malaria vaccine designed to protect through hepatic CD8+ T cell immunity

Science

Volumn 334, Issue 6055, 2011, Pages 475-480

  Epstein, J E ^a   Tewari, K ^b   Lyke, K E ^c   Sim, B K L ^d,e   Billingsley, P F ^d   Laurens, M B ^c,f   Gunasekera, A ^d   Chakravarty, S ^d   James, E R ^d   Sedegah, M ^a   Richman, A ^d   Velmurugan, S ^d   Reyes, S ^a   Li, M ^e   Tucker, K ^g   Ahumada, A ^d,e   Ruben, A J ^d   Li, T ^d   Stafford, R ^d,e   Eappen, A G ^d   Tamminga, C ^a   Bennett, J W ^h   Ockenhouse, C F ^h   Murphy, J R ^h   Komisar, J ^h   Thomas, N ^a   Loyevsky, M ^d   Birkett, A ⁱ   Plowe, C V ^c,f   Loucq, C ⁱ   Edelman, R ^c   Richie, T L ^a   Seder, R A ^b   Hoffman, S L ^d,e   more..

^a NAVAL MEDICAL RESEARCH CENTER   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c University of Maryland School of Medicine Center for Vaccine Development   (United States)

^d SANARIA INC   (United States)

^e Protein Potential LLC   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^g University of Iowa   (United States)

^h WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

ⁱ PATH Malaria Vaccine Initiative   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; LIVE VACCINE; MALARIA VACCINE; SPOROZOITE VACCINE; TUMOR NECROSIS FACTOR ALPHA;

FREQUENCY ANALYSIS; FUNCTIONAL MORPHOLOGY; HEPATITIS; IMMUNE SYSTEM; INFECTIVITY; INOCULATION; MALARIA; MOSQUITO; PRIMATE; PROTOZOAN; RODENT; SUSTAINABILITY; VACCINATION;

ADULT; ARTHRALGIA; ARTICLE; CD8+ T LYMPHOCYTE; CELL STRAIN; CELLULAR IMMUNITY; CHILL; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG SAFETY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FATIGUE; FEVER; HEADACHE; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; LIVER CELL; MAJOR CLINICAL STUDY; MALAISE; MALARIA FALCIPARUM; MOUSE; MUSCULOSKELETAL PAIN; MYALGIA; NAUSEA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPOROZOITE;

ANIMALIA; MUS; PLASMODIUM FALCIPARUM; PRIMATES;

EID: 80055087402     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1211548     Document Type: Article

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