High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity

Vaccine

Volumn 23, Issue 3, 2004, Pages 366-371

  Liu, Wanli ^a   Peng, Zou ^a   Liu, Zuqiang ^a   Lu, Yun ^a   Ding, Jian ^a   Chen, Ying Hua ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Epitope density; Lethal challenge; Protective immunity

Indexed keywords

EPITOPE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROTEIN M2; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; INFLUENZA; INFLUENZA VACCINATION; INFLUENZA VIRUS A; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RABBIT; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; WEIGHT REDUCTION;

ANIMALS; ANTIBODIES, VIRAL; EPITOPES; FEMALE; FLOW CYTOMETRY; GLUTATHIONE TRANSFERASE; IMMUNIZATION; INFLUENZA A VIRUS; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; ORTHOMYXOVIRIDAE INFECTIONS; RABBITS; RECOMBINANT FUSION PROTEINS; SURVIVAL RATE; TIME FACTORS; VIRAL MATRIX PROTEINS; VIRUS REPLICATION;

EID: 7744239182     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.05.028     Document Type: Article

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