-
1
-
-
79960169162
-
Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice
-
Xiao Z, Dallas M, Qiu N, Nicolella D, Cao L, Johnson M, Bonewald L, and, Quarles LD, (2011) Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice. FASEB J 25, 2418 2432.
-
(2011)
FASEB J
, vol.25
, pp. 2418-2432
-
-
Xiao, Z.1
Dallas, M.2
Qiu, N.3
Nicolella, D.4
Cao, L.5
Johnson, M.6
Bonewald, L.7
Quarles, L.D.8
-
2
-
-
33745850756
-
Pathogenic role of Fgf23 in Hyp mice
-
Liu S, Zhou J, Tang W, Jiang X, Rowe DW, and, Quarles LD, (2006) Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab 291, E38 E49.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E38-E49
-
-
Liu, S.1
Zhou, J.2
Tang, W.3
Jiang, X.4
Rowe, D.W.5
Quarles, L.D.6
-
3
-
-
0141500265
-
Evidence for a bone-kidney axis regulating phosphate homeostasis
-
Quarles LD, (2003) Evidence for a bone-kidney axis regulating phosphate homeostasis. J Clin Invest 112, 642-646.
-
(2003)
J Clin Invest
, vol.112
, pp. 642-646
-
-
Quarles, L.D.1
-
4
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for FGF23
-
Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, and, Yamashita T, (2006) Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 444, 770 - 774.
-
(2006)
Nature
, vol.444
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
Iijima, K.4
Hasegawa, H.5
Okawa, K.6
Fujita, T.7
Fukumoto, S.8
Yamashita, T.9
-
5
-
-
38049144010
-
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
-
Chen CD, Podvin S, Gillespie E, Leeman SE, and, Abraham CR, (2007) Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proc Natl Acad Sci USA 104, 19796 - 19801.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19796-19801
-
-
Chen, C.D.1
Podvin, S.2
Gillespie, E.3
Leeman, S.E.4
Abraham, C.R.5
-
6
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, et al. (2006) Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 281, 6120 - 6123.
-
(2006)
J Biol Chem
, vol.281
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
Yamamoto, M.4
Nandi, A.5
Rosenblatt, K.P.6
Baum, M.G.7
Schiavi, S.8
Hu, M.C.9
Moe, O.W.10
-
7
-
-
84906877850
-
Identification of cleavage sites leading to the shed form of the anti-aging protein klotho
-
Chen CD, Tung TY, Liang J, Zeldich E, Tucker Zhou TB, Turk BE, and, Abraham CR, (2014) Identification of cleavage sites leading to the shed form of the anti-aging protein klotho. Biochemistry 53, 5579 - 5587.
-
(2014)
Biochemistry
, vol.53
, pp. 5579-5587
-
-
Chen, C.D.1
Tung, T.Y.2
Liang, J.3
Zeldich, E.4
Tucker Zhou, T.B.5
Turk, B.E.6
Abraham, C.R.7
-
8
-
-
84939561232
-
Shedding of klotho by ADAMs in the kidney
-
van Loon EP, Pulskens WP, van der Hagen EA, Lavrijsen M, Vervloet MG, van Goor H, Bindels RJ, and, Hoenderop JG, (2015) Shedding of klotho by ADAMs in the kidney. Am J Physiol Renal Physiol 309, F359 - F368.
-
(2015)
Am J Physiol Renal Physiol
, vol.309
, pp. F359-F368
-
-
Van Loon, E.P.1
Pulskens, W.P.2
Van Der Hagen, E.A.3
Lavrijsen, M.4
Vervloet, M.G.5
Van Goor, H.6
Bindels, R.J.7
Hoenderop, J.G.8
-
9
-
-
79952201520
-
Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans
-
Chateau MT, Araiz C, Descamps S, and, Galas S, (2010) Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans. Aging 2, 567 - 581.
-
(2010)
Aging
, vol.2
, pp. 567-581
-
-
Chateau, M.T.1
Araiz, C.2
Descamps, S.3
Galas, S.4
-
10
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, et al. (1997) Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390, 45 - 51.
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-o, M.1
Matsumura, Y.2
Aizawa, H.3
Kawaguchi, H.4
Suga, T.5
Utsugi, T.6
Ohyama, Y.7
Kurabayashi, M.8
Kaname, T.9
Kume, E.10
-
11
-
-
84861168067
-
Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis
-
Sugiura H, Yoshida T, Shiohira S, Kohei J, Mitobe M, Kurosu H, Kuro-o M, Nitta K, and, Tsuchiya K, (2012) Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis. Am J Physiol Renal Physiol 302, F1252 - F1264.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F1252-F1264
-
-
Sugiura, H.1
Yoshida, T.2
Shiohira, S.3
Kohei, J.4
Mitobe, M.5
Kurosu, H.6
Kuro-o, M.7
Nitta, K.8
Tsuchiya, K.9
-
12
-
-
84930436563
-
Klotho and phosphate are modulators of pathologic uremic cardiac remodeling
-
Hu MC, Shi M, Cho HJ, Adams-Huet B, Paek J, Hill K, Shelton J, Amaral AP, Faul C, Taniguchi M, et al. (2015) Klotho and phosphate are modulators of pathologic uremic cardiac remodeling. J Am Soc Nephrol 26, 1290 - 1302.
-
(2015)
J Am Soc Nephrol
, vol.26
, pp. 1290-1302
-
-
Hu, M.C.1
Shi, M.2
Cho, H.J.3
Adams-Huet, B.4
Paek, J.5
Hill, K.6
Shelton, J.7
Amaral, A.P.8
Faul, C.9
Taniguchi, M.10
-
13
-
-
84926617077
-
Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway
-
Deng M, Luo Y, Li Y, Yang Q, Deng X, Wu P, and, Ma H, (2015) Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway. Mol Med Rep 12, 45 - 54.
-
(2015)
Mol Med Rep
, vol.12
, pp. 45-54
-
-
Deng, M.1
Luo, Y.2
Li, Y.3
Yang, Q.4
Deng, X.5
Wu, P.6
Ma, H.7
-
14
-
-
84884522131
-
Fibroblast growth factor-23: What we know, what we don't know, and what we need to know
-
Kovesdy CP, and, Quarles LD, (2013) Fibroblast growth factor-23: what we know, what we don't know, and what we need to know. Nephrol Dial Transplant 28, 2228 - 2236.
-
(2013)
Nephrol Dial Transplant
, vol.28
, pp. 2228-2236
-
-
Kovesdy, C.P.1
Quarles, L.D.2
-
15
-
-
49249104701
-
Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
-
Gutierrez OM, Mannstadt M, Isakova T, Rauh-Hain JA, Tamez H, Shah A, Smith K, Lee H, Thadhani R, Juppner H, et al. (2008) Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 359, 584 - 592.
-
(2008)
N Engl J Med
, vol.359
, pp. 584-592
-
-
Gutierrez, O.M.1
Mannstadt, M.2
Isakova, T.3
Rauh-Hain, J.A.4
Tamez, H.5
Shah, A.6
Smith, K.7
Lee, H.8
Thadhani, R.9
Juppner, H.10
-
16
-
-
84863759120
-
Fibroblast growth factor 23 and Inflammation in CKD
-
Munoz Mendoza J, Isakova T, Ricardo AC, Xie H, Navaneethan SD, Anderson AH, Bazzano LA, Xie D, Kretzler M, Nessel L, et al. (2012) Fibroblast growth factor 23 and Inflammation in CKD. Clin J Am Soc Nephrol 7, 1155 - 1162.
-
(2012)
Clin J Am Soc Nephrol
, vol.7
, pp. 1155-1162
-
-
Munoz Mendoza, J.1
Isakova, T.2
Ricardo, A.C.3
Xie, H.4
Navaneethan, S.D.5
Anderson, A.H.6
Bazzano, L.A.7
Xie, D.8
Kretzler, M.9
Nessel, L.10
-
17
-
-
80555148939
-
FGF23 induces left ventricular hypertrophy
-
Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutierrez OM, Aguillon-Prada R, Lincoln J, Hare JM, et al. (2011) FGF23 induces left ventricular hypertrophy. J Clin Invest 121, 4393 - 4408.
-
(2011)
J Clin Invest
, vol.121
, pp. 4393-4408
-
-
Faul, C.1
Amaral, A.P.2
Oskouei, B.3
Hu, M.C.4
Sloan, A.5
Isakova, T.6
Gutierrez, O.M.7
Aguillon-Prada, R.8
Lincoln, J.9
Hare, J.M.10
-
18
-
-
34548497123
-
Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study
-
Fliser D, Kollerits B, Neyer U, Ankerst DP, Lhotta K, Lingenhel A, Ritz E, Kronenberg F, MMKD Study Group, Kuen E, et al. (2007) Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol 18, 2600 - 2608.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2600-2608
-
-
Fliser, D.1
Kollerits, B.2
Neyer, U.3
Ankerst, D.P.4
Lhotta, K.5
Lingenhel, A.6
Ritz, E.7
Kronenberg, F.8
Kuen, E.9
-
19
-
-
79957870135
-
Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease
-
Isakova T, Wahl P, Vargas GS, Gutierrez OM, Scialla J, Xie H, Appleby D, Nessel L, Bellovich K, Chen J, et al. (2011) Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease. Kidney Int 79, 1370 - 1378.
-
(2011)
Kidney Int
, vol.79
, pp. 1370-1378
-
-
Isakova, T.1
Wahl, P.2
Vargas, G.S.3
Gutierrez, O.M.4
Scialla, J.5
Xie, H.6
Appleby, D.7
Nessel, L.8
Bellovich, K.9
Chen, J.10
-
20
-
-
80053517709
-
FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis
-
Kendrick J, Cheung AK, Kaufman JS, Greene T, Roberts WL, Smits G, Chonchol M, and HOST Investigators (2011) FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis. J Am Soc Nephrol 22, 1913 - 1922.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1913-1922
-
-
Kendrick, J.1
Cheung, A.K.2
Kaufman, J.S.3
Greene, T.4
Roberts, W.L.5
Smits, G.6
Chonchol, M.7
-
21
-
-
85047687476
-
Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease
-
Scialla JJ, and, Wolf M, (2014) Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease. Nat Rev Nephrol 10, 268 - 278.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 268-278
-
-
Scialla, J.J.1
Wolf, M.2
-
22
-
-
84897969679
-
Vitamin D and risk of cause specific death: Systematic review and meta-analysis of observational cohort and randomised intervention studies
-
Chowdhury R, Kunutsor S, Vitezova A, Oliver-Williams C, Chowdhury S, Kiefte-de-Jong JC, Khan H, Baena CP, Prabhakaran D, Hoshen MB, et al. (2014) Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ 348, g1903.
-
(2014)
BMJ
, vol.348
-
-
Chowdhury, R.1
Kunutsor, S.2
Vitezova, A.3
Oliver-Williams, C.4
Chowdhury, S.5
Kiefte-De-Jong, J.C.6
Khan, H.7
Baena, C.P.8
Prabhakaran, D.9
Hoshen, M.B.10
-
23
-
-
84955613345
-
Low vitamin D and high fibroblast growth factor 23 serum levels associate with infectious and cardiac deaths in the HEMO Study
-
pii: ASN.2014101009. Epub ahead of print
-
Chonchol M, Greene T, Zhang Y, Hoofnagle AN, and, Cheung AK, (2015) Low vitamin D and high fibroblast growth factor 23 serum levels associate with infectious and cardiac deaths in the HEMO Study. Journal of the American Society of Nephrology: JASN. pii: ASN.2014101009. [Epub ahead of print].
-
(2015)
Journal of the American Society of Nephrology: JASN
-
-
Chonchol, M.1
Greene, T.2
Zhang, Y.3
Hoofnagle, A.N.4
Cheung, A.K.5
-
24
-
-
78651398351
-
Macrophages in renal disease
-
Wang Y, and, Harris DC, (2011) Macrophages in renal disease. J Am Soc Nephrol 22, 21 - 27.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 21-27
-
-
Wang, Y.1
Harris, D.C.2
-
25
-
-
84923061601
-
Role of innate and adaptive immune mechanisms in cardiac injury and repair
-
Epelman S, Liu PP, and, Mann DL, (2015) Role of innate and adaptive immune mechanisms in cardiac injury and repair. Nat Rev Immunol 15, 117 - 129.
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 117-129
-
-
Epelman, S.1
Liu, P.P.2
Mann, D.L.3
-
26
-
-
84875882608
-
Correlation between vitamin D and cardiovascular disease predictors in overweight and obese Koreans
-
Kim M, Na W, and, Sohn C, (2013) Correlation between vitamin D and cardiovascular disease predictors in overweight and obese Koreans. J Clin Biochem Nutr 52, 167 - 171.
-
(2013)
J Clin Biochem Nutr
, vol.52
, pp. 167-171
-
-
Kim, M.1
Na, W.2
Sohn, C.3
-
27
-
-
33646367420
-
Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
-
Liu S, Tang W, Zhou J, Stubbs JR, Luo Q, Pi M, and, Quarles LD, (2006) Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 17, 1305 - 1315.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1305-1315
-
-
Liu, S.1
Tang, W.2
Zhou, J.3
Stubbs, J.R.4
Luo, Q.5
Pi, M.6
Quarles, L.D.7
-
28
-
-
84929359317
-
1,25-Dihydroxyvitamin D3 promotes high glucose-induced M1 macrophage switching to M2 via the VDR-PPARgamma signaling pathway
-
Zhang X, Zhou M, Guo Y, Song Z, and, Liu B, (2015) 1,25-Dihydroxyvitamin D3 promotes high glucose-induced M1 macrophage switching to M2 via the VDR-PPARgamma signaling pathway. BioMed Res Int 2015, 157834.
-
(2015)
BioMed Res Int
, vol.2015
-
-
Zhang, X.1
Zhou, M.2
Guo, Y.3
Song, Z.4
Liu, B.5
-
29
-
-
0021358280
-
Macrophage activation to kill Leishmania tropica: Defective intracellular killing of amastigotes by macrophages elicited with sterile inflammatory agents
-
Hoover DL, and, Nacy CA, (1984) Macrophage activation to kill Leishmania tropica: defective intracellular killing of amastigotes by macrophages elicited with sterile inflammatory agents. J Immunol 132, 1487 - 1493.
-
(1984)
J Immunol
, vol.132
, pp. 1487-1493
-
-
Hoover, D.L.1
Nacy, C.A.2
-
30
-
-
58849167699
-
The isolation and characterization of murine macrophages
-
Chapter 14, Unit 14 1
-
Zhang X, Goncalves R, and, Mosser DM, (2008) The isolation and characterization of murine macrophages. Curr Protoc Immunol Chapter 14, Unit 14 1.
-
(2008)
Curr Protoc Immunol
-
-
Zhang, X.1
Goncalves, R.2
Mosser, D.M.3
-
31
-
-
84876941701
-
CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells
-
Jacobs ET, Van Pelt C, Forster RE, Zaidi W, Hibler EA, Galligan MA, Haussler MR, and, Jurutka PW, (2013) CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells. Cancer Res 73, 2563 - 2573.
-
(2013)
Cancer Res
, vol.73
, pp. 2563-2573
-
-
Jacobs, E.T.1
Van Pelt, C.2
Forster, R.E.3
Zaidi, W.4
Hibler, E.A.5
Galligan, M.A.6
Haussler, M.R.7
Jurutka, P.W.8
-
32
-
-
27644530602
-
LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia
-
Qin H, Wilson CA, Lee SJ, Zhao X, and, Benveniste EN, (2005) LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia. Blood 106, 3114 - 3122.
-
(2005)
Blood
, vol.106
, pp. 3114-3122
-
-
Qin, H.1
Wilson, C.A.2
Lee, S.J.3
Zhao, X.4
Benveniste, E.N.5
-
33
-
-
16544367410
-
Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system
-
Cantorna MT, Zhu Y, Froicu M, and, Wittke A, (2004) Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr 80, 1717S - 1720S.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 1717S-1720S
-
-
Cantorna, M.T.1
Zhu, Y.2
Froicu, M.3
Wittke, A.4
-
34
-
-
79960386992
-
Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization
-
Shalhoub V, Ward SC, Sun B, Stevens J, Renshaw L, Hawkins N, and, Richards WG, (2011) Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization. Calcif Tissue Int 89, 140 - 150.
-
(2011)
Calcif Tissue Int
, vol.89
, pp. 140-150
-
-
Shalhoub, V.1
Ward, S.C.2
Sun, B.3
Stevens, J.4
Renshaw, L.5
Hawkins, N.6
Richards, W.G.7
-
35
-
-
84929582868
-
Expression of Fgf23 in activated dendritic cells and macrophages in response to immunological stimuli in mice
-
Masuda Y, Ohta H, Morita Y, Nakayama Y, Miyake A, Itoh N, and, Konishi M, (2015) Expression of Fgf23 in activated dendritic cells and macrophages in response to immunological stimuli in mice. Biol Pharm Bull 38, 687 - 693.
-
(2015)
Biol Pharm Bull
, vol.38
, pp. 687-693
-
-
Masuda, Y.1
Ohta, H.2
Morita, Y.3
Nakayama, Y.4
Miyake, A.5
Itoh, N.6
Konishi, M.7
-
36
-
-
84872841888
-
Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes
-
Bacchetta J, Sea JL, Chun RF, Lisse TS, Wesseling-Perry K, Gales B, Adams JS, Salusky IB, and, Hewison M, (2013) Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res 28, 46 - 55.
-
(2013)
J Bone Miner Res
, vol.28
, pp. 46-55
-
-
Bacchetta, J.1
Sea, J.L.2
Chun, R.F.3
Lisse, T.S.4
Wesseling-Perry, K.5
Gales, B.6
Adams, J.S.7
Salusky, I.B.8
Hewison, M.9
-
37
-
-
38549122739
-
Unexpected actions of vitamin D: New perspectives on the regulation of innate and adaptive immunity
-
Adams JS, and, Hewison M, (2008) Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 4, 80 - 90.
-
(2008)
Nat Clin Pract Endocrinol Metab
, vol.4
, pp. 80-90
-
-
Adams, J.S.1
Hewison, M.2
-
38
-
-
84876669460
-
1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: Evidence for primary and secondary mechanisms modulated by leptin and interleukin-6
-
Saini RK, Kaneko I, Jurutka PW, Forster R, Hsieh A, Hsieh JC, Haussler MR, and, Whitfield GK, (2013) 1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6. Calcif Tissue Int 92, 339 - 353.
-
(2013)
Calcif Tissue Int
, vol.92
, pp. 339-353
-
-
Saini, R.K.1
Kaneko, I.2
Jurutka, P.W.3
Forster, R.4
Hsieh, A.5
Hsieh, J.C.6
Haussler, M.R.7
Whitfield, G.K.8
-
39
-
-
79953737375
-
The bone and beyond: -Dem bones’ are made for more than walking
-
Quarles LD, (2011) The bone and beyond: -Dem bones’ are made for more than walking. Nat Med 17, 428 - 430.
-
(2011)
Nat Med
, vol.17
, pp. 428-430
-
-
Quarles, L.D.1
-
40
-
-
84901841829
-
Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells
-
Kundu R, Chain BM, Coussens AK, Khoo B, and, Noursadeghi M, (2014) Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells. Eur J Immunol 44, 1781 - 1790.
-
(2014)
Eur J Immunol
, vol.44
, pp. 1781-1790
-
-
Kundu, R.1
Chain, B.M.2
Coussens, A.K.3
Khoo, B.4
Noursadeghi, M.5
-
41
-
-
84898775593
-
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis
-
Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, and, Dixon JE, (2014) Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci USA 111, 5520 - 5525.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 5520-5525
-
-
Tagliabracci, V.S.1
Engel, J.L.2
Wiley, S.E.3
Xiao, J.4
Gonzalez, D.J.5
Nidumanda Appaiah, H.6
Koller, A.7
Nizet, V.8
White, K.E.9
Dixon, J.E.10
-
42
-
-
20344368596
-
Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis
-
Stawowy P, Meyborg H, Stibenz D, Borges Pereira Stawowy N, Roser M, Thanabalasingam U, Veinot JP, Chretien M, Seidah NG, Fleck E, et al. (2005) Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis. Circulation 111, 2820 - 2827.
-
(2005)
Circulation
, vol.111
, pp. 2820-2827
-
-
Stawowy, P.1
Meyborg, H.2
Stibenz, D.3
Borges Pereira Stawowy, N.4
Roser, M.5
Thanabalasingam, U.6
Veinot, J.P.7
Chretien, M.8
Seidah, N.G.9
Fleck, E.10
-
43
-
-
84901745038
-
FGF23 regulates renal sodium handling and blood pressure
-
Andrukhova O, Slavic S, Smorodchenko A, Zeitz U, Shalhoub V, Lanske B, Pohl EE, and, Erben RG, (2014) FGF23 regulates renal sodium handling and blood pressure. EMBO Mol Med 6, 744 - 759.
-
(2014)
EMBO Mol Med
, vol.6
, pp. 744-759
-
-
Andrukhova, O.1
Slavic, S.2
Smorodchenko, A.3
Zeitz, U.4
Shalhoub, V.5
Lanske, B.6
Pohl, E.E.7
Erben, R.G.8
-
44
-
-
65649103814
-
Initial FGF23-mediated signaling occurs in the distal convoluted tubule
-
Farrow EG, Davis SI, Summers LJ, and, White KE, (2009) Initial FGF23-mediated signaling occurs in the distal convoluted tubule. J Am Soc Nephrol 20, 955 - 960.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 955-960
-
-
Farrow, E.G.1
Davis, S.I.2
Summers, L.J.3
White, K.E.4
-
45
-
-
84924170646
-
Klotho gene deficiency causes salt-sensitive hypertension via monocyte chemotactic protein-1/CC chemokine receptor 2-mediated inflammation
-
Zhou X, Chen K, Lei H, and, Sun Z, (2015) Klotho gene deficiency causes salt-sensitive hypertension via monocyte chemotactic protein-1/CC chemokine receptor 2-mediated inflammation. J Am Soc Nephrol 26, 121 - 132.
-
(2015)
J Am Soc Nephrol
, vol.26
, pp. 121-132
-
-
Zhou, X.1
Chen, K.2
Lei, H.3
Sun, Z.4
-
46
-
-
77949558495
-
ADAM-17: The enzyme that does it all
-
Gooz M, (2010) ADAM-17: the enzyme that does it all. Crit Rev Biochem Mol Biol 45, 146 - 169.
-
(2010)
Crit Rev Biochem Mol Biol
, vol.45
, pp. 146-169
-
-
Gooz, M.1
-
47
-
-
80755156297
-
Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling
-
Kubin T, Poling J, Kostin S, Gajawada P, Hein S, Rees W, Wietelmann A, Tanaka M, Lorchner H, Schimanski S, et al. (2011) Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling. Cell Stem Cell 9, 420 - 432.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 420-432
-
-
Kubin, T.1
Poling, J.2
Kostin, S.3
Gajawada, P.4
Hein, S.5
Rees, W.6
Wietelmann, A.7
Tanaka, M.8
Lorchner, H.9
Schimanski, S.10
-
48
-
-
84866127175
-
A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model
-
Dai B, David V, Martin A, Huang J, Li H, Jiao Y, Gu W, and, Quarles LD, (2012) A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model. PLoS ONE 7, e44161.
-
(2012)
PLoS ONE
, vol.7
-
-
Dai, B.1
David, V.2
Martin, A.3
Huang, J.4
Li, H.5
Jiao, Y.6
Gu, W.7
Quarles, L.D.8
-
49
-
-
84906934479
-
Inflammatory processes in renal fibrosis
-
Meng XM, Nikolic-Paterson DJ, and, Lan HY, (2014) Inflammatory processes in renal fibrosis. Nat Rev Nephrol 10, 493 - 503.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 493-503
-
-
Meng, X.M.1
Nikolic-Paterson, D.J.2
Lan, H.Y.3
-
50
-
-
84923096359
-
Regulation of renal fibrosis by macrophage polarization
-
Pan B, Liu G, Jiang Z, and, Zheng D, (2015) Regulation of renal fibrosis by macrophage polarization. Cell Physiol Biochem 35, 1062 - 1069.
-
(2015)
Cell Physiol Biochem
, vol.35
, pp. 1062-1069
-
-
Pan, B.1
Liu, G.2
Jiang, Z.3
Zheng, D.4
-
51
-
-
34547461118
-
Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease
-
Wang Y, Wang YP, Zheng G, Lee VW, Ouyang L, Chang DH, Mahajan D, Coombs J, Wang YM, Alexander SI, et al. (2007) Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. Kidney Int 72, 290 â€" 299.
-
(2007)
Kidney Int
, vol.72
, pp. 290-299
-
-
Wang, Y.1
Wang, Y.P.2
Zheng, G.3
Lee, V.W.4
Ouyang, L.5
Chang, D.H.6
Mahajan, D.7
Coombs, J.8
Wang, Y.M.9
Alexander, S.I.10
-
52
-
-
0037378759
-
Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism
-
Ikezumi Y, Atkins RC, and, Nikolic-Paterson DJ, (2003) Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism. J Am Soc Nephrol 14, 888 - 898.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 888-898
-
-
Ikezumi, Y.1
Atkins, R.C.2
Nikolic-Paterson, D.J.3
-
53
-
-
84906790428
-
25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes
-
Riek AE, Oh J, Darwech I, Moynihan CE, Bruchas RR, and, Bernal-Mizrachi C, (2014) 25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes. J Steroid Biochem Mol Biol. 144 (Pt A), 172 - 179.
-
(2014)
J Steroid Biochem Mol Biol
, vol.144
, pp. 172-179
-
-
Riek, A.E.1
Oh, J.2
Darwech, I.3
Moynihan, C.E.4
Bruchas, R.R.5
Bernal-Mizrachi, C.6
-
54
-
-
84863115528
-
Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: The PRIMO randomized controlled trial
-
Thadhani R, Appelbaum E, Pritchett Y, Chang Y, Wenger J, Tamez H, Bhan I, Agarwal R, Zoccali C, Wanner C, et al. (2012) Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial. JAMA 307, 674 - 684.
-
(2012)
JAMA
, vol.307
, pp. 674-684
-
-
Thadhani, R.1
Appelbaum, E.2
Pritchett, Y.3
Chang, Y.4
Wenger, J.5
Tamez, H.6
Bhan, I.7
Agarwal, R.8
Zoccali, C.9
Wanner, C.10
-
55
-
-
84878487994
-
FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy
-
Touchberry CD, Green TM, Tchikrizov V, Mannix JE, Mao TF, Carney BW, Girgis M, Vincent RJ, Wetmore LA, Dawn B, et al. (2013) FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy. Am J Physiol Endocrinol Metab 304, E863 - E873.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.304
, pp. E863-E873
-
-
Touchberry, C.D.1
Green, T.M.2
Tchikrizov, V.3
Mannix, J.E.4
Mao, T.F.5
Carney, B.W.6
Girgis, M.7
Vincent, R.J.8
Wetmore, L.A.9
Dawn, B.10
-
56
-
-
78651408919
-
Klotho deficiency causes vascular calcification in chronic kidney disease
-
Hu MC, Shi M, Zhang J, Quinones H, Griffith C, Kuro-o M, and, Moe OW, (2011) Klotho deficiency causes vascular calcification in chronic kidney disease. J Am Soc Nephrol 22, 124 - 136.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 124-136
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
Quinones, H.4
Griffith, C.5
Kuro-o, M.6
Moe, O.W.7
-
57
-
-
84938929605
-
The failing heart is a major source of circulating FGF23 via oncostatin M receptor activation
-
Richter M, and, Walther LH, (2015) The failing heart is a major source of circulating FGF23 via oncostatin M receptor activation. J Heart Lung Transplant 34, 1211 - 1214.
-
(2015)
J Heart Lung Transplant
, vol.34
, pp. 1211-1214
-
-
Richter, M.1
Walther, L.H.2
|