Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Acta Neuropathologica

Volumn 131, Issue 6, 2016, Pages 833-845

  Qaddoumi, Ibrahim ^a   Orisme, Wilda ^a   Wen, Ji ^a   Santiago, Teresa ^a   Gupta, Kirti ^a   Dalton, James D ^a   Tang, Bo ^a   Haupfear, Kelly ^a   Punchihewa, Chandanamali ^a   Easton, John ^a   Mulder, Heather ^a   Boggs, Kristy ^a   Shao, Ying ^a   Rusch, Michael ^a   Becksfort, Jared ^a   Gupta, Pankaj ^a   Wang, Shuoguo ^a   Lee, Ryan P ^a   Brat, Daniel ^b   Peter Collins, V ^c   Dahiya, Sonika ^d   George, David ^e   Konomos, William ^f   Kurian, Kathreena M ^g   McFadden, Kathryn ^h   Serafini, Luciano Neder ⁱ   Nickols, Hilary ^j   Perry, Arie ^k   Shurtleff, Sheila ^a   Gajjar, Amar ^a   Boop, Fredrick A ^a   Klimo, Paul D ^a   Mardis, Elaine R ^d   Wilson, Richard K ^d   Baker, Suzanne J ^a   Zhang, Jinghui ^a   Wu, Gang ^a   Downing, James R ^a   Tatevossian, Ruth G ^a   Ellison, David W ^a   more..

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Foothills Medical Center   (United States)

^f Innovative Pathology Services Knoxville   (United States)

^g FRENCHAY HOSPITAL   (United Kingdom)

^h UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF SÃO PAULO   (Brazil)

^j VANDERBILT UNIVERSITY   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

BRAF; FGFR1; Glioma; Glioneuronal; MYB; RNA seq

Indexed keywords

B RAF KINASE; FIBROBLAST GROWTH FACTOR RECEPTOR 1; PROTEIN MYB; TRANSCRIPTOME; BRAF PROTEIN, HUMAN; FGFR1 PROTEIN, HUMAN; MYBBP1A PROTEIN, HUMAN; MYBL1 PROTEIN, HUMAN; NUCLEAR PROTEIN; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; ONCOPROTEIN; TRANSACTIVATOR PROTEIN;

ANGIOCENTRIC GLIOMA; ARTICLE; COPY NUMBER VARIATION; DIFFUSE ASTROCYTOMA; DIFFUSE OLIGODENDROGLIAL TUMOR; DNA METHYLATION ASSAY; DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GLIOMA; HUMAN; LOW GRADE NEUROEPITHELIAL TUMOR; MAJOR CLINICAL STUDY; NEUROEPITHELIOMA; OLIGODENDROGLIA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; ADOLESCENT; ADULT; ASTROCYTOMA; BRAIN TUMOR; CHILD; FEMALE; GENETIC PREDISPOSITION; GENETICS; INFANT; MALE; MUTATION; ONCOGENE MYB; PATHOLOGY; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; ASTROCYTOMA; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; GANGLIOGLIOMA; GENES, MYB; GENETIC PREDISPOSITION TO DISEASE; GLIOMA; HUMANS; INFANT; MALE; MUTATION; NUCLEAR PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; TRANS-ACTIVATORS; YOUNG ADULT;

EID: 84955315769     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-016-1539-z     Document Type: Article

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