-
1
-
-
34347266011
-
Pilocytic astrocytoma
-
David N, Louis MD, Hiroko Ohgaki PD, Otmar D, Wiestler MD, Webster K, Cavenee PD, editors. Lyon, France: IARC Press
-
Scheithauer BW, Hawkins C, Tihan T, et al. Pilocytic astrocytoma. In: David N, Louis MD, Hiroko Ohgaki PD, Otmar D, Wiestler MD, Webster K, Cavenee PD, editors. WHO Classification of Tumours of the Central Nervous System. World Health Organization Classification of Tumours. Lyon, France: IARC Press, 2007:13-21
-
(2007)
WHO Classification of Tumours of the Central Nervous System. World Health Organization Classification of Tumours
, pp. 13-21
-
-
Scheithauer, B.W.1
Hawkins, C.2
Tihan, T.3
-
2
-
-
84899413788
-
Childhood and adolescent cancer statistics, 2014
-
Ward E, DeSantis C, Robbins A, et al. Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin 2014;64:83-103
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 83-103
-
-
Ward, E.1
DeSantis, C.2
Robbins, A.3
-
3
-
-
84868023931
-
CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2005-2009
-
Dolecek TA, Propp JM, Stroup NE, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. Neuro Oncol 2012;14(Suppl 5):v1-49
-
(2012)
Neuro Oncol
, vol.14
, pp. v1-v49
-
-
Dolecek, T.A.1
Propp, J.M.2
Stroup, N.E.3
-
5
-
-
27744454314
-
Epidemiology of pediatric tumors of the nervous system according to the WHO 2000 classification: A report of 1,195 cases from a single institution
-
Rosemberg S, Fujiwara D. Epidemiology of pediatric tumors of the nervous system according to the WHO 2000 classification: a report of 1,195 cases from a single institution. Child Nerv Sys 2005;21:940-4
-
(2005)
Child Nerv Sys
, vol.21
, pp. 940-944
-
-
Rosemberg, S.1
Fujiwara, D.2
-
6
-
-
84901040227
-
Adult pilocytic astrocytomas: Clinical features and molecular analysis
-
Theeler BJ, Ellezam B, Sadighi ZS, et al. Adult pilocytic astrocytomas: clinical features and molecular analysis. Neuro Oncol 2014 2014;16:841-7. doi: 10.1093/neuonc/not246
-
(2014)
Neuro Oncol 2014
, vol.16
, pp. 841-847
-
-
Theeler, B.J.1
Ellezam, B.2
Sadighi, Z.S.3
-
7
-
-
84862900240
-
MAPK pathway activation in pilocytic astrocytoma
-
Jones DT, Gronych J, Lichter P, et al. MAPK pathway activation in pilocytic astrocytoma. Cell Molec Life Sci 2012;69:1799-811
-
(2012)
Cell Molec Life Sci
, vol.69
, pp. 1799-1811
-
-
Jones, D.T.1
Gronych, J.2
Lichter, P.3
-
8
-
-
84862826608
-
Pilocytic astrocytoma survival in adults: Analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute
-
Johnson DR, Brown PD, Galanis E, et al. Pilocytic astrocytoma survival in adults: analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute. J Neuro-oncol 2012;108:187-93
-
(2012)
J Neuro-oncol
, vol.108
, pp. 187-193
-
-
Johnson, D.R.1
Brown, P.D.2
Galanis, E.3
-
9
-
-
84874602325
-
Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma
-
Gutmann DH, McLellan MD, Hussain I, et al. Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma. Genome Res 2013;23:431-9
-
(2013)
Genome Res
, vol.23
, pp. 431-439
-
-
Gutmann, D.H.1
McLellan, M.D.2
Hussain, I.3
-
10
-
-
41649113333
-
Gliomas in neurofibromatosis type 1: A clinicopathologic study of 100 patients
-
Rodriguez FJ, Perry A, Gutmann DH, et al. Gliomas in neurofibromatosis type 1: a clinicopathologic study of 100 patients. J Neuropathol Exp Neurol 2008;67:240-9
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 240-249
-
-
Rodriguez, F.J.1
Perry, A.2
Gutmann, D.H.3
-
12
-
-
0142092642
-
Preliminary observations on genetic alterations in pilocytic astrocytomas associated with neurofibromatosis 1
-
Tada K, Kochi M, Saya H, et al. Preliminary observations on genetic alterations in pilocytic astrocytomas associated with neurofibromatosis 1. Neuro Oncol 2003;5:228-34
-
(2003)
Neuro Oncol
, vol.5
, pp. 228-234
-
-
Tada, K.1
Kochi, M.2
Saya, H.3
-
13
-
-
34248583922
-
MAPKs: Function, regulation, role in cancer and therapeutic targeting
-
Dhanasekaran DN, Johnson GL. MAPKs: function, regulation, role in cancer and therapeutic targeting. Oncogene 2007;26:3097-9
-
(2007)
Oncogene
, vol.26
, pp. 3097-3099
-
-
Dhanasekaran, D.N.1
Johnson, G.L.2
-
14
-
-
78049510048
-
Expression and functional role of negative signalling regulators in tumour development and progression
-
Murphy T, Hori S, Sewell J, et al. Expression and functional role of negative signalling regulators in tumour development and progression. Int J Cancer 2010;127:2491-9
-
(2010)
Int J Cancer
, vol.127
, pp. 2491-2499
-
-
Murphy, T.1
Hori, S.2
Sewell, J.3
-
15
-
-
84880983541
-
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
-
Jones DT, Hutter B, Jager N, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Gen 2013;45:927-32
-
(2013)
Nature Gen
, vol.45
, pp. 927-932
-
-
Jones, D.T.1
Hutter, B.2
Jager, N.3
-
16
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
Zhang J, Wu G, Miller CP, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Gen 2013;45:602-12
-
(2013)
Nature Gen
, vol.45
, pp. 602-612
-
-
Zhang, J.1
Wu, G.2
Miller, C.P.3
-
17
-
-
52649172327
-
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
-
Bar EE, Lin A, Tihan T, et al. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol 2008;67:878-87
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 878-887
-
-
Bar, E.E.1
Lin, A.2
Tihan, T.3
-
18
-
-
79959580390
-
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
-
Capper D, Preusser M, Habel A, et al. Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody. Acta Neuropathol 2011;122:11-9
-
(2011)
Acta Neuropathol
, vol.122
, pp. 11-19
-
-
Capper, D.1
Preusser, M.2
Habel, A.3
-
19
-
-
66849099801
-
Activation of the ERK/MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas
-
Forshew T, Tatevossian RG, Lawson AR, et al. Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J Pathol 2009;218:172-81
-
(2009)
J Pathol
, vol.218
, pp. 172-181
-
-
Forshew, T.1
Tatevossian, R.G.2
Lawson, A.R.3
-
20
-
-
80055084211
-
BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults
-
Hasselblatt M, Riesmeier B, Lechtape B, et al. BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults. Neuropathol Appl Neurobiol 2011;37:803-6
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, pp. 803-806
-
-
Hasselblatt, M.1
Riesmeier, B.2
Lechtape, B.3
-
21
-
-
79960388615
-
BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma
-
Hawkins C, Walker E, Mohamed N, et al. BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma. Clin Cancer Res 2011;17:4790-8
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4790-4798
-
-
Hawkins, C.1
Walker, E.2
Mohamed, N.3
-
22
-
-
79954441895
-
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
-
Schindler G, Capper D, Meyer J, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol 2011;121:397-405
-
(2011)
Acta Neuropathol
, vol.121
, pp. 397-405
-
-
Schindler, G.1
Capper, D.2
Meyer, J.3
-
23
-
-
82955249323
-
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas
-
Tian Y, Rich BE, Vena N, et al. Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. J Molec Diag 2011;13:669-77
-
(2011)
J Molec Diag
, vol.13
, pp. 669-677
-
-
Tian, Y.1
Rich, B.E.2
Vena, N.3
-
24
-
-
67349219657
-
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
-
Jones DT, Kocialkowski S, Liu L, et al. Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene 2009;28:2119-23
-
(2009)
Oncogene
, vol.28
, pp. 2119-2123
-
-
Jones, D.T.1
Kocialkowski, S.2
Liu, L.3
-
25
-
-
84922698954
-
Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade gliomas
-
Roth JJ, Santi M, Pollock AN, et al. Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade gliomas. Brain Pathol 2015;25:182-92
-
(2015)
Brain Pathol
, vol.25
, pp. 182-192
-
-
Roth, J.J.1
Santi, M.2
Pollock, A.N.3
-
26
-
-
79958087774
-
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
-
Cin H, Meyer C, Herr R, et al. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol 2011;121:763-74
-
(2011)
Acta Neuropathol
, vol.121
, pp. 763-774
-
-
Cin, H.1
Meyer, C.2
Herr, R.3
-
27
-
-
84899451831
-
The molecular and cell biology of pediatric low-grade gliomas
-
Chen YH, Gutmann DH. The molecular and cell biology of pediatric low-grade gliomas. Oncogene 2014;33:2019-26
-
(2014)
Oncogene
, vol.33
, pp. 2019-2026
-
-
Chen, Y.H.1
Gutmann, D.H.2
-
28
-
-
16344395995
-
Mutation analysis of B-RAF gene in human gliomas
-
Basto D, Trovisco V, Lopes JM, et al. Mutation analysis of B-RAF gene in human gliomas. Acta Neuropathol 2005;109:207-10
-
(2005)
Acta Neuropathol
, vol.109
, pp. 207-210
-
-
Basto, D.1
Trovisco, V.2
Lopes, J.M.3
-
29
-
-
84901324707
-
FGFR1 mutations in rosette-forming glioneuronal tumors of the fourth ventricle
-
Gessi M, Moneim YA, Hammes J, et al. FGFR1 mutations in rosette-forming glioneuronal tumors of the fourth ventricle. J Neuropathol Exp Neurol 2014;73:580-4
-
(2014)
J Neuropathol Exp Neurol
, vol.73
, pp. 580-584
-
-
Gessi, M.1
Moneim, Y.A.2
Hammes, J.3
-
30
-
-
79958112619
-
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
-
Dutt A, Ramos AH, Hammerman PS, et al. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PloS One 2011;6:e20351
-
(2011)
PloS One
, vol.6
-
-
Dutt, A.1
Ramos, A.H.2
Hammerman, P.S.3
-
31
-
-
0027218571
-
FGFRI and PLAT genes and DNA amplification at 8p12 in breast and ovarian cancers
-
Theillet C, Adelaide J, Louason G, et al. FGFRI and PLAT genes and DNA amplification at 8p12 in breast and ovarian cancers. Genes Chromosome Cancer 1993;7:219-26
-
(1993)
Genes Chromosome Cancer
, vol.7
, pp. 219-226
-
-
Theillet, C.1
Adelaide, J.2
Louason, G.3
-
32
-
-
84865805666
-
Transforming fusions of FGFR and TACC genes in human glioblastoma
-
Singh D, Chan JM, Zoppoli P, et al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science 2012;337:1231-5
-
(2012)
Science
, vol.337
, pp. 1231-1235
-
-
Singh, D.1
Chan, J.M.2
Zoppoli, P.3
-
33
-
-
84883647983
-
Outcome analysis of childhood pilocytic astrocytomas: A retrospective study of 148 cases at a single institution
-
Colin C, Padovani L, Chappe C, et al. Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution. Neuropathol Appl Neurobiol 2013;39:693-705
-
(2013)
Neuropathol Appl Neurobiol
, vol.39
, pp. 693-705
-
-
Colin, C.1
Padovani, L.2
Chappe, C.3
-
34
-
-
0041353859
-
Pilocytic astrocytomas in children: Prognostic factors - A retrospective study of 80 cases
-
discussion 54-5
-
Fernandez C, Figarella-Branger D, Girard N, et al. Pilocytic astrocytomas in children: prognostic factors - a retrospective study of 80 cases. Neurosurgery 2003;53:544-53; discussion 54-5
-
(2003)
Neurosurgery
, vol.53
, pp. 544-553
-
-
Fernandez, C.1
Figarella-Branger, D.2
Girard, N.3
-
35
-
-
71349083949
-
In pursuit of prognostic factors in children with pilocytic astrocytomas
-
Paixao Becker A, de Oliveira RS, Saggioro FP, et al. In pursuit of prognostic factors in children with pilocytic astrocytomas. Childs Nerv Syst 2010;26:19-28
-
(2010)
Childs Nerv Syst
, vol.26
, pp. 19-28
-
-
Paixao Becker, A.1
De Oliveira, R.S.2
Saggioro, F.P.3
-
36
-
-
0026580081
-
Benign cerebellar astrocytomas of childhood
-
discussion 3
-
Schneider JH Jr, Raffel C, McComb JG. Benign cerebellar astrocytomas of childhood. Neurosurgery 1992;30:58-62; discussion 3
-
(1992)
Neurosurgery
, vol.30
, pp. 58-62
-
-
Schneider, J.H.1
Raffel, C.2
McComb, J.G.3
-
37
-
-
71549122009
-
Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
-
Capper D, Weissert S, Balss J, et al. Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol 2010;20:245-54
-
(2010)
Brain Pathol
, vol.20
, pp. 245-254
-
-
Capper, D.1
Weissert, S.2
Balss, J.3
-
38
-
-
82955165744
-
IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors
-
Mellai M, Piazzi A, Caldera V, et al. IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors. J Neuro-oncol 2011;105:345-57
-
(2011)
J Neuro-oncol
, vol.105
, pp. 345-357
-
-
Mellai, M.1
Piazzi, A.2
Caldera, V.3
-
39
-
-
84907916641
-
T-box transcription factor brachyury is associated with prostate cancer progression and aggressiveness
-
Pinto F, Pertega-Gomes N, Pereira MS, et al. T-box transcription factor brachyury is associated with prostate cancer progression and aggressiveness. Clinical Cancer Res 2014;20:4949-61
-
(2014)
Clinical Cancer Res
, vol.20
, pp. 4949-4961
-
-
Pinto, F.1
Pertega-Gomes, N.2
Pereira, M.S.3
-
40
-
-
84899669381
-
Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease
-
Toschi L, Finocchiaro G, Nguyen TT, et al. Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease. PloS One 2014;9:e95303
-
(2014)
PloS One
, vol.9
-
-
Toschi, L.1
Finocchiaro, G.2
Nguyen, T.T.3
-
41
-
-
84893116875
-
ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers
-
Aisner DL, Nguyen TT, Paskulin DD, et al. ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers. Molec Cancer Res 2014;12:111-8
-
(2014)
Molec Cancer Res
, vol.12
, pp. 111-118
-
-
Aisner, D.L.1
Nguyen, T.T.2
Paskulin, D.D.3
-
42
-
-
84893717646
-
Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer
-
Schultheis AM, Bos M, Schmitz K, et al. Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer. Mod Pathol 2014;27:214-21
-
(2014)
Mod Pathol
, vol.27
, pp. 214-221
-
-
Schultheis, A.M.1
Bos, M.2
Schmitz, K.3
-
43
-
-
84923068430
-
KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy
-
Yamane LS, Scapulatempo-Neto C, Alvarenga L, et al. KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy. Oncology Rep 2014;32:1419-26
-
(2014)
Oncology Rep
, vol.32
, pp. 1419-1426
-
-
Yamane, L.S.1
Scapulatempo-Neto, C.2
Alvarenga, L.3
-
44
-
-
0031213685
-
Cytogenetic analysis of 120 primary pediatric brain tumors and literature review
-
Bhattacharjee MB, Armstrong DD, Vogel H, et al. Cytogenetic analysis of 120 primary pediatric brain tumors and literature review. Cancer Gen Cytogen 1997;97:39-53
-
(1997)
Cancer Gen Cytogen
, vol.97
, pp. 39-53
-
-
Bhattacharjee, M.B.1
Armstrong, D.D.2
Vogel, H.3
-
45
-
-
0030818739
-
Chromosomal characteristics of childhood brain tumors
-
Bigner SH, McLendon RE, Fuchs H, et al. Chromosomal characteristics of childhood brain tumors. Cancer Gen Cytogen 1997;97:125-34
-
(1997)
Cancer Gen Cytogen
, vol.97
, pp. 125-134
-
-
Bigner, S.H.1
McLendon, R.E.2
Fuchs, H.3
-
46
-
-
43049124130
-
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
-
Pfister S, Janzarik WG, Remke M, et al. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest 2008;118:1739-49
-
(2008)
J Clin Invest
, vol.118
, pp. 1739-1749
-
-
Pfister, S.1
Janzarik, W.G.2
Remke, M.3
-
47
-
-
66949147222
-
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene
-
Sievert AJ, Jackson EM, Gai X, et al. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol 2009;19:449-58
-
(2009)
Brain Pathol
, vol.19
, pp. 449-458
-
-
Sievert, A.J.1
Jackson, E.M.2
Gai, X.3
-
48
-
-
84930386971
-
V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior
-
Bannykh SI, Mirocha J, Nuno M, et al. V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior. Cli Neuropathol 2014;33:388-98
-
(2014)
Cli Neuropathol
, vol.33
, pp. 388-398
-
-
Bannykh, S.I.1
Mirocha, J.2
Nuno, M.3
-
49
-
-
80054790555
-
BRAF mutations in advanced cancers: Clinical characteristics and outcomes
-
El-Osta H, Falchook G, Tsimberidou A, et al. BRAF mutations in advanced cancers: clinical characteristics and outcomes. PloS One 2011;6:e25806
-
(2011)
PloS One
, vol.6
-
-
El-Osta, H.1
Falchook, G.2
Tsimberidou, A.3
-
50
-
-
84862584008
-
Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma
-
Menzies AM, Haydu LE, Visintin L, et al. Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma. Clinical Cancer Res 2012;18:3242-9
-
(2012)
Clinical Cancer Res
, vol.18
, pp. 3242-3249
-
-
Menzies, A.M.1
Haydu, L.E.2
Visintin, L.3
-
51
-
-
77955493250
-
Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032
-
Rubinstein JC, Sznol M, Pavlick AC, et al. Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032. J Transl Med 2010;8:67
-
(2010)
J Transl Med
, vol.8
, pp. 67
-
-
Rubinstein, J.C.1
Sznol, M.2
Pavlick, A.C.3
-
52
-
-
84876040346
-
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
-
Sievert AJ, Lang SS, Boucher KL, et al. Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas. Proc Natl Acad Sci USA 2013;110:5957-62
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 5957-5962
-
-
Sievert, A.J.1
Lang, S.S.2
Boucher, K.L.3
-
53
-
-
84899473817
-
Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas
-
Bautista F, Paci A, Minard-Colin V, et al. Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas. Ped Blood Cancer 2014;61:1101-3
-
(2014)
Ped Blood Cancer
, vol.61
, pp. 1101-1103
-
-
Bautista, F.1
Paci, A.2
Minard-Colin, V.3
-
54
-
-
84899485468
-
Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy
-
Robinson GW, Orr BA, Gajjar A. Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy. BMC Cancer 2014;14:258
-
(2014)
BMC Cancer
, vol.14
, pp. 258
-
-
Robinson, G.W.1
Orr, B.A.2
Gajjar, A.3
-
55
-
-
0028153931
-
Expression of fibroblast growth factor receptor-1 in human glioma and meningioma tissues
-
discussion 5-6
-
Ueba T, Takahashi JA, Fukumoto M, et al. Expression of fibroblast growth factor receptor-1 in human glioma and meningioma tissues. Neurosurgery 1994;34:221-5; discussion 5-6
-
(1994)
Neurosurgery
, vol.34
, pp. 221-225
-
-
Ueba, T.1
Takahashi, J.A.2
Fukumoto, M.3
-
56
-
-
84902669919
-
FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI ensitivity across all lung cancer histologies
-
Wynes MW, Hinz TK, Gao D, et al. FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI ensitivity across all lung cancer histologies. Clin Cancer Res 2014;20:3299-309
-
(2014)
Clin Cancer Res
, vol.20
, pp. 3299-3309
-
-
Wynes, M.W.1
Hinz, T.K.2
Gao, D.3
-
57
-
-
84925408760
-
Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors
-
Soria JC, DeBraud F, Bahleda R, et al. Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors. Ann Oncol 2014;25:2244-51
-
(2014)
Ann Oncol
, vol.25
, pp. 2244-2251
-
-
Soria, J.C.1
DeBraud, F.2
Bahleda, R.3
-
58
-
-
84918793590
-
The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor
-
Nakanishi Y, Akiyama N, Tsukaguchi T, et al. The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor. Molec Cancer Ther 2014;13:2547-58
-
(2014)
Molec Cancer Ther
, vol.13
, pp. 2547-2558
-
-
Nakanishi, Y.1
Akiyama, N.2
Tsukaguchi, T.3
|