Patz1 regulates embryonic stem cell identity

Stem Cells and Development

Volumn 23, Issue 10, 2014, Pages 1062-1073

  Ow, Jin Rong ^a   Ma, Hui ^a   Jean, Angela ^a   Goh, Ziyi ^a   Lee, Yun Hwa ^a   Chong, Yew Mei ^a   Soong, Richie ^b   Fu, Xin Yuan ^a,b   Yang, Henry ^b   Wu, Qiang ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN PATZ1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTOME; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; HOMEODOMAIN PROTEIN; NANOG PROTEIN, MOUSE; POU5F1 PROTEIN, MOUSE; REPRESSOR PROTEIN; TUMOR PROTEIN; ZFP278 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL CYCLE; CELL METABOLISM; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEVELOPMENTAL GENE; DOWN REGULATION; EMBRYOID BODY; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENE OVEREXPRESSION; GENE SILENCING; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DNA RESPONSIVE ELEMENT; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL LINE; EMBRYOID BODIES; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MICE; NEOPLASM PROTEINS; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; REPRESSOR PROTEINS; RESPONSE ELEMENTS;

EID: 84900459544     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2013.0430     Document Type: Article

References (49)

1. Evans M and MH Kaufman. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-156.
2. Thomson JA, J Itskovitz-Eldor, SS Shapiro, MA Waknitz, JJ Swiergiel, VS Marshall and JM Jones. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147.
3. Nichols J, D Davidson, T Taga, K Yoshida, I Chambers and A Smith. (1996). Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis. Mech Dev 57:123-131.
4. Ying QL, J Nichols, I Chambers and A Smith. (2003). BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115:281-292.
5. Sato N, L Meijer, L Skaltsounis, P Greengard and AH Brivanlou. (2004). Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 10:55-63.
6. Xu RH, RM Peck, DS Li, X Feng, T Ludwig and JA Thomson. (2005). Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2:185-190.
7. Brons IGM, LE Smithers, MWB Trotter, P Rugg-Gunn, B Sun, SM Chuva de Sousa Lopes, SK Howlett, A Clarkson, L Ahrlund-Richter, RA Pedersen and L Vallier. (2007). Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448:191-195.
8. Tesar PJ, JG Chenoweth, FA Brook, TJ Davies, EP Evans, DL Mack, RL Gardner and RD McKay. (2007). New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448:196-199.
9. Nichols J, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, I Chambers, H Schöler and A Smith. (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379-391.
10. Niwa H, J Miyazaki and AG Smith. (2000). Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 24:372-376.
11. Avilion AA, SK Nicolis, LH Pevny, L Perez, N Vivian and R Lovell-Badge. (2003). Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17:126-140.
12. Masui S, Y Nakatake, Y Toyooka, D Shimosato, R Yagi, K Takahashi, H Okochi, A Okuda, R Matoba, et al. (2007). Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 9:625-635.
13. Chambers I, D Colby, M Robertson, J Nichols, S Lee, S Tweedie and A Smith. (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113:643-655.
14. Mitsui K, Y Tokuzawa, H Itoh, K Segawa, M Murakam, K Takahashi, M Maruyama, M Maeda and S Yamanaka. (2003). The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-642.
15. Boyer LA, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, MG Guenther, RM Kumar, HL Murray, et al. (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122:947-956.
16. Chen X, H Xu, P Yuan, F Fang, M Huss, VB Vega, E Wong, YL Orlov, W Zhang, et al. (2008). Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-1117.
17. Kim J, J Chu, X Shen, J Wang and SH Orkin. (2008). An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132:1049-1061.
18. Loh YH, Q Wu, JL Chew, VB Vega, W Zhang, X Chen, G Bourque, J George, B Leong, et al. (2006). The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38:431-440.
19. Takahashi K and S Yamanaka. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676.
20. Yoshikawa T, Y Piao, J Zhong, R Matoba, MG Carter, Y Wang, I Goldberg and MS Ko. (2006). High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization. Gene Expr Patterns 6:213-224.
21. Zhang J, WL Tam, GQ Tong, Q Wu, HY Chan, BS Soh, Y Lou, J Yang, Y Ma, et al. (2006). Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1. Nat Cell Biol 8:1114-1123.
22. Wu Q, X Chen, J Zhang, YH Loh, TY Low, W Zhang, W Zhang, SK Sze, B Lim and HH Ng. (2006). Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells. J Biol Chem 281:24090-24094.
23. Lim LS, YH Loh, W Zhang, Y Li, X Chen, Y Wang, M Bakre, HH Ng and LW Stanton. (2007). Zic3 is required for maintenance of pluripotency in embryonic stem cells. Mol Biol Cell 18:1348-1358.
24. Wang ZX, JLL Kueh, CHL Teh, M Rossbach, L Lim, P Li, KY Wong, T Lufkin, P Robson and LW Stanton. (2007). Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells. Stem Cells 25:2173-2182.
25. Yu H, G Kunarso, FH Hong and LW Stanton. (2009). Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells. J Biol Chem 284:31327-31335.
26. X Chen, F Fang, YC Liou, HH Ng. (2008). Zfp143 regulates Nanog through modulation of Oct4 binding. Stem Cells 26:2759-2767.
27. Wang ZX, CHL Teh, CMY Chan, C Chu, M Rossbach, G Kunarso, TB Allapitchay, KY Wong and LW Stanton. (2008). The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes. Stem Cells 26:2791-2799.
28. Kobayashi A, H Yamagiwa, H Hoshino, A Muto, K Sato, M Morita, N Hayashi, M Yamamoto and K Igarashi. (2000). A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.Mol Cell Biol 20:1733-1746.
29. Mastrangelo T, P Modena, S Tornielli, F Bullrich, MA Testi, A Mezzelani, P Radice, A Azzarelli, S Pilotti, et al. (2000). A novel zinc finger gene is fused to EWS in small round cell tumor. Oncogene 19: 3799-3804.
30. Tang F, C Barbacioru, S Bao, C Lee, E Nordman, X Wang, K Lao and MA Surani. (2010). Tracing the derivation of embryonic stem cells from the inner cell mass by singlecell RNA-Seq analysis. Cell Stem Cell 6:468-478.
31. Nishiyama A, L Xin, AA Sharov, M Thomas, G Mowrer, E Meyers, Y Piao, S Mehta, S Yee, et al. (2009). Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5:420-433.
32. Lee YH, H Ma, TZ Tan, SS Ng, R Soong, S Mori, XY Fu, M Zernicka-Goetz and Q Wu. (2012). Protein arginine methyltransferase 6 regulates embryonic stem cell identity. Stem Cells Dev 21:2613-2622.
33. Eisen MB, PT Spellman, PO Brown and D Botstein. (1998). Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 95:14863-14868.
34. Boyle EI, S Weng, J Gollub, H Jin, D Botstein, JM Cherry and G Sherlock. (2004). GO::TermFinder-open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes. Bioinformatics 20:3710-3715.
35. Wu Q, AW Bruce, A Jedrusik, PD Ellis, RM Andrews, CF Langford,DMGlover andMZernicka-Goetz. (2009).CARM1 is required in embryonic stem cells to maintain pluripotency and resist differentiation. Stem Cells 27:2637-2645.
36. Zeineddine D, E Papadimou, K Chebli, M Gineste, J Liu, C Grey, S Thurig, A Behfar, VA Wallace, IS Skerjanc and M Pucéat. (2006). Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development. Dev Cell 11:535-546.
37. Valentino T, D Palmieri, M Vitiello, A Simeone, G Palma, C Arra, P Chieffi, L Chiariotti, A Fusco and M Fedele. (2013). Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene. J Cell Physiol 228:646-653.
38. Chew JL, YH Loh, W Zhang, X Chen, WL Tam, LS Yeap, P Li, YS Ang, B Lim, P Robson and HH Ng. (2005). Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 25:6031-6046.
39. Yeom YI, G Fuhrmann, CE Ovitt, A Brehm, K Ohbo, M Gross, K Hübner and HR Schöler. (1996). Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development 122:881-894.
40. Rodda DJ, JL Chew, LH Lim, YH Loh, B Wang, HH Ng and P Robson. (2005). Transcriptional regulation of nanog by OCT4 and SOX2. J Biol Chem 280:24731-24737.
41. Ouyang Z, Q Zhou and WH Wong. (2009). ChIP-Seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells. Proc Natl Acad Sci U S A 106:21521-21526.
42. Leahy A, JW Xiong, F Kuhnert and H Stuhlmann. (1999). Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation. J Exp Zool 284:67-81.
43. Qin J, X Guo, GH Cui, YC Zhou, DR Zhou, AF Tang, ZD Yu, YT Gui and ZM Cai. (2009). Cluster characterization of mouse embryonic stem cell-derived pluripotent embryoid bodies in four distinct developmental stages. Biologicals 37:235-244.
44. Li X, H Peng, DC Schultz, JM Lopez-Guisa, FJ 3rd Rauscher and R Marmorstein. (1999). Structure-function studies of the BTB/POZ transcriptional repression domain from the promyelocytic leukemia zinc finger oncoprotein. Cancer Res 59:5275-5282.
45. Pero R, D Palmieri, T Angrisano, T Valentino, A Federico, R Franco, F Lembo, AJ Klein-Szanto, L Del Vecchio, et al. (2012). POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation. J Biol Chem 287:18308-18317.
46. Nordhoff V, K Hübner, A Bauer, I Orlova, A Malapetsa and HR Schöler. (2001). Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences. Mamm Genome 12:309-317.
47. Kuroda T, M Tada, H Kubota, H Kimura, SY Hatano, H Suemori, N Nakatsuji and T Tada. (2005). Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol 25:2475-2485.
48. Kelly KF and JM Daniel. (2006). POZ for effect-POZ-ZF transcription factors in cancer and development. Trends Cell Biol 16:578-587.
49. Bilic I, C Koesters, B Unger, M Sekimata, A Hertweck, R Maschek, CB Wilson and W Ellmeier. (2006). Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat Immunol 7:392-400.