Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects

Journal of Proteomics

Volumn 128, Issue , 2015, Pages 306-320

  Titz, Bjoern ^a   Sewer, Alain ^a   Schneider, Thomas ^a   Elamin, Ashraf ^a   Martin, Florian ^a   Dijon, Sophie ^a   Luettich, Karsta ^a   Guedj, Emmanuel ^a   Vuillaume, Gregory ^a   Ivanov, Nikolai V ^a   Peck, Michael J ^a   Chaudhary, Nveed I ^a   Hoeng, Julia ^a   Peitsch, Manuel C ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

Author keywords

COPD; Quantitative proteomics; Smoking; Sputum; Systems toxicology

Indexed keywords

APOLIPOPROTEIN A1; MUCIN; PROTEOME; SALBUTAMOL; SPUTUM PROTEOME; TRANSCRIPTOME; TREFOIL PEPTIDE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; ASYMPTOMATIC DISEASE; CELL POLARITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOCOMPETENT CELL; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; OXIDATIVE STRESS; PARALLEL DESIGN; PASSIVE SMOKING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; SMOKING; SMOKING CESSATION; SPUTUM; TRANSCRIPTOMICS; BLOOD; CAUSALITY; COMORBIDITY; GREAT BRITAIN; METABOLISM; MIDDLE AGED; PREVALENCE; PREVENTION AND CONTROL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RANDOMIZED CONTROLLED TRIAL; REPRODUCIBILITY; RISK FACTOR; SENSITIVITY AND SPECIFICITY; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; BIOMARKERS; CAUSALITY; COMORBIDITY; FEMALE; GREAT BRITAIN; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PROTEOME; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REPRODUCIBILITY OF RESULTS; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SMOKING; SMOKING CESSATION; SPUTUM; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 84955314531     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2015.08.009     Document Type: Article

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