Induced sputum metalloproteinases and their inhibitors in relation to exhaled nitrogen oxide and sputum nitric oxides and other inflammatory cytokines in patients with chronic obstructive pulmonary disease

Journal of Physiology and Pharmacology

Volumn 59, Issue SUPPL. 6, 2008, Pages 809-817

  Ziora, D ^a   Dworniczak, S ^a   Kozielski, J ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Chronic obstructive pulmonery disease; Induced sputum; Inhibitors of metalloproteinases; Metalloproteinases; Nitrogen oxide

Indexed keywords

CYTOKINE; GELATINASE A; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; METALLOPROTEINASE; NITRATE; NITRITE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE; NITRIC OXIDE; NITROGEN OXIDE; PROTEINASE INHIBITOR;

ADULT; AGED; AIRWAY OBSTRUCTION; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME REGULATION; ENZYME SYNTHESIS; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; MALE; PATHOGENESIS; SMOKING; SPUTUM LEVEL; BIOSYNTHESIS; BLOOD; ENZYMOLOGY; EXTRACELLULAR SPACE; LEUKOCYTE COUNT; LUNG FUNCTION TEST; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SPIROMETRY; SPUTUM;

ADULT; CYTOKINES; EXTRACELLULAR SPACE; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASES; MIDDLE AGED; NITRIC OXIDE; NITROGEN OXIDES; PROTEASE INHIBITORS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; SMOKING; SPIROMETRY; SPUTUM;

EID: 64549100682     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Buist AS. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. Buist AS (ed). 2006, pp. 1-88. 1-22-2007. MCR VISION, Inc.
2. Shapiro SD, Campbell EJ. Matrix degrading proteinases. In Asthma and COPD. Barnes PJ, Drazen JM, Rennard JM, Thomson NC (eds), New York, Academic Press Elsevier Science, 2002, pp. 274-282.
3. Shipley JM, Wesselschmidt RL, Kobayashi DK, Ley TJ, Shapiro SD. Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci USA 1996; 93: 3942-3946.
4. Palmgren MS, deShazo RD, Carter RM, Zimny ML, Shah SV. Mechanisms of neutrophil damage to human alveolar extracellular matrix: the role of serine and metalloproteases. J Allergy Clin Immunol 1992; 89: 905-915.
5. Gueders MM, Foidart JM, Noel A, Cataldo DD. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: potential implications in asthma and other lung diseases. Eur J Pharmacol 2006; 533: 133-144.
6. Shapiro SD. Proteinases in chronic obstructive pulmonary disease. Biochem Soc Trans 2002; 30: 98-102.
7. Stockley RA, Bayley DL. Validation of assays for inflammatory mediators in sputum. Eur Respir J2000; 15: 778-781.
8. Ziora D, Dworniczak S, Kaczmarczyk G, Jastrzebski D, Krzywiecki A, Kozielski J. Correlation of exhaled nitric oxide with nitrogen oxides and selected cytokines in induced sputum of chronic obstructive pulmonary disease patients. J Physiol Pharmacol 2007; 58 Suppl 5: 791-799.
9. Morris DG, Huang X, Kaminski N et al. Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature 2003; 422: 169-173.
10. Imai K, Dalal SS, Chen ES et al. Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema. Am J Respir Crit Care Med 2001; 163: 786-791.
11. Finlay GA, O'Driscoll LR, Russell KJ et al. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med 1997; 156: 240-247.
12. Russell RE, Culpitt SV, DeMatos C et al. Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2002; 26: 602-609.
13. Segura-Valdez L, Pardo A, Gaxiola M, Uhal BD, Becerril C, Selman M. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 2000; 117: 684-694.
14. Ohnishi K, Takagi M, Kurokawa Y, Satomi S, Konttinen YT. Matrix metalloproteinase- mediated extracellular matrix protein degradation in human pulmonary emphysema. Lab Invest 1998; 78: 1077-1087.
15. Vignola AM, Paganin F, Capieu L et al. Airway remodelling assessed by sputum and high- resolution computed tomography in asthma and COPD. Eur Respir J2004; 24: 910-917.
16. Vignola AM, Riccobono L, Mirabella A et al. Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis. Am J Respir Crit Care Med 1998; 158: 1945-1950.
17. Culpitt SV, Rogers DF, Traves SL, Barnes PJ, Donnelly LE. Sputum matrix metalloproteases: comparison between chronic obstructive pulmonary disease and asthma. Respir Med 2005; 99: 703-710.
18. Vernooy JH, Lindeman JH, Jacobs JA, Hanemaaijer R, Wouters EF. Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD. Chest 2004; 126: 1802-1810.
19. Baraldo S, Bazzan E, Zanin ME et al. Matrix metalloproteinase-2 protein in lung periphery is related to COPD progression. Chest 2007; 132: 733-1740.
20. Barnes PJ. Mediators of chronic obstructive pulmonary disease. Pharmacol Rev 2004; 56: 515-548.
21. Moreau M, Brocheriou I, Petit L, Ninio E, Chapman MJ, Rouis M. Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: relevance to stability of atherosclerotic plaque. Circulation 1999; 99: 420-426.
22. Okamoto T, Valacchi G, Gohil K, Akaike T, van d, V. S-nitrosothiols inhibit cytokine-mediated induction of matrix metalloproteinase-9 in airway epithelial cells. Am J Respir Cell Mol Biol 2002; 27: 463-473.
23. Ridnour LA, Windhausen AN, Isenberg JS et al. Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proc Natl Acad Sci USA 2007; 104: 16898-16903.
24. Warner RL, Beltran L, Younkin EM et al. Role of stromelysin 1 and gelatinase B in experimental acute lung injury. Am J Respir Cell Mol Biol 2001; 24: 537-544.