DKK3 blocked translocation of β-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 12, 2015, Pages 2832-2841

  Guo, Qingqu ^a   Qin, Wenjie ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

EMT; Chemotherapy; DKK 3; Pancreatic cancer; catenin

Indexed keywords

BETA CATENIN; DICKKOPF RELATED PROTEIN 3; GEMCITABINE; GLYCOPROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DKK3 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PANCREAS CANCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; TUMOR VOLUME; WESTERN BLOTTING; ACTIVE TRANSPORT; ANALOGS AND DERIVATIVES; ANIMAL; CELL HYPOXIA; CELL MOTION; CELL NUCLEUS; DNA METHYLATION; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; NUDE MOUSE; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BETA CATENIN; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL NUCLEUS; CELL PROLIFERATION; DEOXYCYTIDINE; DNA METHYLATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE, NUDE; MICROSCOPY, CONFOCAL; MIDDLE AGED; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84955180465     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12675     Document Type: Article

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