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Volumn 20, Issue 4, 2013, Pages 507-514

DKK3 is a potential tumor suppressor gene in papillary thyroid carcinoma

Author keywords

DKK3; DNA methylation; Thyroid carcinoma; Thyroid tumorigenesis; Tumor suppressor gene

Indexed keywords

AZACITIDINE; MESSENGER RNA;

EID: 84882739653     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-13-0053     Document Type: Article
Times cited : (33)

References (45)
  • 1
    • 27544457678 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase
    • doi:10.1158/0008-5472.CAN-05-0829
    • Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kurose K, Ebara S, Miyazaki M, Namba M, Kumon H & Huh NH 2005 Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase. Cancer Research 65 9617-9622. (doi:10.1158/0008-5472.CAN-05-0829)
    • (2005) Cancer Research , vol.65 , pp. 9617-9622
    • Abarzua, F.1    Sakaguchi, M.2    Takaishi, M.3    Nasu, Y.4    Kurose, K.5    Ebara, S.6    Miyazaki, M.7    Namba, M.8    Kumon, H.9    Huh, N.H.10
  • 3
    • 1642418216 scopus 로고    scopus 로고
    • Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development
    • doi:10.1016/j.modgep.2003.11.002
    • Ang SJ, Stump RJ, Lovlcu FJ & McAvoy JW 2004 Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expression Patterns 4 289-295. (doi:10.1016/j.modgep.2003.11.002)
    • (2004) Gene Expression Patterns , vol.4 , pp. 289-295
    • Ang, S.J.1    Stump, R.J.2    Lovlcu, F.J.3    McAvoy, J.W.4
  • 4
    • 0036927738 scopus 로고    scopus 로고
    • Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning
    • doi:10.1242/dev.00154
    • Davidson G, Mao B, Barco Barrantes I & Niehrs C 2002 Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. Development 129 5587-5596. (doi:10.1242/dev.00154)
    • (2002) Development , vol.129 , pp. 5587-5596
    • Davidson, G.1    Mao, B.2    Barco Barrantes, I.3    Niehrs, C.4
  • 5
    • 33646442046 scopus 로고    scopus 로고
    • Increasing incidence of thyroid cancer in the United States, 1973-2002
    • doi:10.1001/jama.295.18.2164
    • Davies L & Welch HG 2006 Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 295 2164-2167. (doi:10.1001/jama.295.18.2164)
    • (2006) JAMA , vol.295 , pp. 2164-2167
    • Davies, L.1    Welch, H.G.2
  • 6
    • 7444235421 scopus 로고    scopus 로고
    • Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signaling in the developing mouse forebrain
    • doi:10.1016/j.devbrainres.2004.09.008
    • Diep DB, Hoen N, Backman M, Machon O & Krauss S 2004 Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signaling in the developing mouse forebrain. Brain Research. Developmental Brain Research 153 261-270. (doi:10.1016/j.devbrainres.2004.09.008)
    • (2004) Brain Research. Developmental Brain Research , vol.153 , pp. 261-270
    • Diep, D.B.1    Hoen, N.2    Backman, M.3    Machon, O.4    Krauss, S.5
  • 8
    • 17444408187 scopus 로고    scopus 로고
    • Dynamic expression of Wnt signaling-regulated Dickkopf-1, -2, and -3 mRNAs in the developing mouse tooth
    • doi:10.1002/dvdy.20285
    • Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH & Luukko K 2005 Dynamic expression of Wnt signaling-regulated Dickkopf-1, -2, and -3 mRNAs in the developing mouse tooth. Developmental Dynamics 233 161-166. (doi:10.1002/dvdy.20285)
    • (2005) Developmental Dynamics , vol.233 , pp. 161-166
    • Fjeld, K.1    Kettunen, P.2    Furmanek, T.3    Kvinnsland, I.H.4    Luukko, K.5
  • 10
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • doi:10.1038/34848
    • Glinka A, Wu W, Delius H, Delius H, Monaghan AP, Blumenstock C & Niehrs C 1998 Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391 357-362. (doi:10.1038/34848)
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Delius, H.4    Monaghan, A.P.5    Blumenstock, C.6    Niehrs, C.7
  • 12
    • 48249084096 scopus 로고    scopus 로고
    • Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer
    • doi:10.1002/cncr.23548
    • Guan H, Ji M, Hou P, Liu Z, Wang C, Shan Z, Teng W & Xing M 2008 Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer. Cancer 113 247-255. (doi:10.1002/cncr.23548)
    • (2008) Cancer , vol.113 , pp. 247-255
    • Guan, H.1    Ji, M.2    Hou, P.3    Liu, Z.4    Wang, C.5    Shan, Z.6    Teng, W.7    Xing, M.8
  • 14
    • 11244323971 scopus 로고    scopus 로고
    • Dickkopf-3/REIC functions as a suppressor gene of tumor growth
    • doi:10.1038/sj.onc.1208138
    • Hsieh SY, Hsieh PS, Chiu CT & Chen WY 2004 Dickkopf-3/REIC functions as a suppressor gene of tumor growth. Oncogene 23 9183-9189. (doi:10.1038/sj.onc.1208138)
    • (2004) Oncogene , vol.23 , pp. 9183-9189
    • Hsieh, S.Y.1    Hsieh, P.S.2    Chiu, C.T.3    Chen, W.Y.4
  • 16
    • 0037045429 scopus 로고    scopus 로고
    • Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells
    • doi:10.1016/S0378-1119(01)00838-1
    • Kobayashi K, Ouchida M, Tsuji T, Hanafusa H, Miyazaki M, Namba M, Shimizu N & Shimizu K 2002 Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells. Gene 282 151-158. (doi:10.1016/S0378-1119(01)00838-1)
    • (2002) Gene , vol.282 , pp. 151-158
    • Kobayashi, K.1    Ouchida, M.2    Tsuji, T.3    Hanafusa, H.4    Miyazaki, M.5    Namba, M.6    Shimizu, N.7    Shimizu, K.8
  • 18
    • 33747348443 scopus 로고    scopus 로고
    • Expression of Dickkopf genes is strongly reduced in malignant melanoma
    • doi:10.1038/sj.onc.1209508
    • Kuphal S, Lodermeyer S, Bataille F, Schuierer M, Hoang BH & Bosserhoff AK 2006 Expression of Dickkopf genes is strongly reduced in malignant melanoma. Oncogene 238 301-313. (doi:10.1038/sj.onc.1209508)
    • (2006) Oncogene , vol.238 , pp. 301-313
    • Kuphal, S.1    Lodermeyer, S.2    Bataille, F.3    Schuierer, M.4    Hoang, B.H.5    Bosserhoff, A.K.6
  • 20
    • 33845564665 scopus 로고    scopus 로고
    • RIZ1 is epigenetically inactivated by promoter
    • doi:10.1002/cncr.22325
    • Lal G, Padmanabha L & Smith BJ 2006 RIZ1 is epigenetically inactivated by promoter. Cancer 107 2752-2759. (doi:10.1002/cncr.22325)
    • (2006) Cancer , vol.107 , pp. 2752-2759
    • Lal, G.1    Padmanabha, L.2    Smith, B.J.3
  • 21
    • 47249111724 scopus 로고    scopus 로고
    • Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung
    • doi:10.1093/carcin/bgn017
    • Licchesi JD, Westra WH, Hooker CM, Machida EO, Baylin SB & Herman JG 2008 Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. Carcinogenesis 29 895-904. (doi:10.1093/carcin/bgn017)
    • (2008) Carcinogenesis , vol.29 , pp. 895-904
    • Licchesi, J.D.1    Westra, W.H.2    Hooker, C.M.3    Machida, E.O.4    Baylin, S.B.5    Herman, J.G.6
  • 22
    • 20144383392 scopus 로고    scopus 로고
    • Functional epigenomics identifies genes frequently silenced in prostate cancer
    • doi:10.1158/0008-5472.CAN-04-4407
    • Lodygin D, Epanchintsev A, Menssen A, Diebold J & Hermeking H 2005 Functional epigenomics identifies genes frequently silenced in prostate cancer. Cancer Research 65 4218-4227. (doi:10.1158/0008-5472.CAN-04-4407)
    • (2005) Cancer Research , vol.65 , pp. 4218-4227
    • Lodygin, D.1    Epanchintsev, A.2    Menssen, A.3    Diebold, J.4    Hermeking, H.5
  • 25
    • 77957816367 scopus 로고    scopus 로고
    • Analysis of Dickkopf3 interactions with Wnt signaling receptors
    • doi:10.3109/08977191003738832
    • Nakamura RE & Hackam AS 2010 Analysis of Dickkopf3 interactions with Wnt signaling receptors. Growth Factors 28 232-242. (doi:10.3109/ 08977191003738832)
    • (2010) Growth Factors , vol.28 , pp. 232-242
    • Nakamura, R.E.1    Hackam, A.S.2
  • 26
    • 28444466586 scopus 로고    scopus 로고
    • Dkk-1,-2, and -3 expression in mouse craniofacial development
    • doi:10.1007/s10735-005-9008-3
    • Nie X 2005 Dkk-1,-2, and -3 expression in mouse craniofacial development. Journal of Molecular Histology 36 367-372. (doi:10.1007/s10735-005-9008-3)
    • (2005) Journal of Molecular Histology , vol.36 , pp. 367-372
    • Nie, X.1
  • 32
    • 0042671128 scopus 로고    scopus 로고
    • Zonal expression of dickkopf-3 and components of the Wnt signaling pathways in the human adrenal cortex
    • doi:10.1677/joe.0.1780149
    • Suwa T, Chen M, Hawks CL & Hornsby PJ 2003 Zonal expression of dickkopf-3 and components of the Wnt signaling pathways in the human adrenal cortex. Journal of Endocrinology 178 149-158. (doi:10.1677/joe.0.1780149)
    • (2003) Journal of Endocrinology , vol.178 , pp. 149-158
    • Suwa, T.1    Chen, M.2    Hawks, C.L.3    Hornsby, P.J.4
  • 34
    • 33646247418 scopus 로고    scopus 로고
    • Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection
    • doi:10.1158/1078-0432.CCR-05-2468
    • Urakami S, Shiina H, Enokida H, Kawakami T, Kawamoto K, Hirata H, Tanaka Y, Kikuno N, Nakagawa M, Igawa M et al. 2006 Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. Clinical Cancer Research 12 2109-2116. (doi:10.1158/1078-0432.CCR-05-2468)
    • (2006) Clinical Cancer Research , vol.12 , pp. 2109-2116
    • Urakami, S.1    Shiina, H.2    Enokida, H.3    Kawakami, T.4    Kawamoto, K.5    Hirata, H.6    Tanaka, Y.7    Kikuno, N.8    Nakagawa, M.9    Igawa, M.10
  • 35
    • 75649094543 scopus 로고    scopus 로고
    • Aberrant DNA methylation in contrast with mutations
    • doi:10.1111/j.1349-7006.2009.01434.x
    • Ushijima T & Asada K 2010 Aberrant DNA methylation in contrast with mutations. Cancer Science 101 300-305. (doi:10.1111/j.1349-7006.2009.01434.x)
    • (2010) Cancer Science , vol.101 , pp. 300-305
    • Ushijima, T.1    Asada, K.2
  • 37
    • 80054083873 scopus 로고    scopus 로고
    • Targeting the Wnt pathway in cancer: The emerging role of Dickkopf-3
    • doi:10.1016/j.bbcan.2011.09.003
    • Veeck J & Dahl E 2012 Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3. Biochimica et Biophysica Acta 1825 18-28. (doi:10.1016/j.bbcan.2011.09.003)
    • (2012) Biochimica et Biophysica Acta , vol.1825 , pp. 18-28
    • Veeck, J.1    Dahl, E.2
  • 38
    • 59449089531 scopus 로고    scopus 로고
    • Wnt signaling in human breast cancer: Expression of the putative Wnt inhibitor Dickkopf (Dkk3) is frequently suppressed by promoter hypermethylation in mammary tumors
    • doi:10.1186/bcr2151
    • Veeck J, Bektas N, Hartmann A, Kristiansen G, Heindrichs U, Knüchel R & Dahl E 2008 Wnt signaling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf (Dkk3) is frequently suppressed by promoter hypermethylation in mammary tumors. Breast Cancer Research 10 R82. (doi:10.1186/bcr2151)
    • (2008) Breast Cancer Research , vol.10
    • Veeck, J.1    Bektas, N.2    Hartmann, A.3    Kristiansen, G.4    Heindrichs, U.5    Knüchel, R.6    Dahl, E.7
  • 39
    • 68349139365 scopus 로고    scopus 로고
    • Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (Dkk3) promoter methylation in human breast cancer
    • doi:10.1186/1471-2407-9-217
    • Veeck J, Wild PJ, Fuchs T, Schüffler PJ, Hartmann A, Knuchel R & Dahl E 2009 Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (Dkk3) promoter methylation in human breast cancer. BMC Cancer 9 217. (doi:10.1186/1471-2407-9-217)
    • (2009) BMC Cancer , vol.9 , pp. 217
    • Veeck, J.1    Wild, P.J.2    Fuchs, T.3    Schüffler, P.J.4    Hartmann, A.5    Knuchel, R.6    Dahl, E.7
  • 40
    • 33847073463 scopus 로고    scopus 로고
    • Gene methylation in thyroid tumorigenesis
    • doi:10.1210/en.2006-0927
    • Xing M 2007 Gene methylation in thyroid tumorigenesis. Endocrinology 148 948-953. (doi:10.1210/en.2006-0927)
    • (2007) Endocrinology , vol.148 , pp. 948-953
    • Xing, M.1
  • 41
    • 77955826140 scopus 로고    scopus 로고
    • Homozygous deletion but not mutation of exons 5 and 8 of the fragile histidine triad (FHIT) gene is associated with features of differentiated thyroid carcinoma
    • Yin DT, Wang L, Sun J, Yin F, Yan Q, Shen RL, Gao JX & He G 2010a Homozygous deletion but not mutation of exons 5 and 8 of the fragile histidine triad (FHIT) gene is associated with features of differentiated thyroid carcinoma. Annals of Clinical Laboratory Science 40 267-272.
    • (2010) Annals of Clinical Laboratory Science , vol.40 , pp. 267-272
    • Yin, D.T.1    Wang, L.2    Sun, J.3    Yin, F.4    Yan, Q.5    Shen, R.L.6    Gao, J.X.7    He, G.8
  • 42
    • 77956033429 scopus 로고    scopus 로고
    • Association of the promoter methylation and protein expression of fragile histidine triad (FHIT) gene with the progression of differentiated thyroid carcinoma
    • Yin DT, Wang L, Sun J, Yin F, Yan Q, Shen R, He G & Gao JX 2010b Association of the promoter methylation and protein expression of fragile histidine triad (FHIT) gene with the progression of differentiated thyroid carcinoma. International Journal of Clinical and Experimental Pathology 3 482-491.
    • (2010) International Journal of Clinical and Experimental Pathology , vol.3 , pp. 482-491
    • Yin, D.T.1    Wang, L.2    Sun, J.3    Yin, F.4    Yan, Q.5    Shen, R.6    He, G.7    Gao, J.X.8
  • 43
    • 81155135155 scopus 로고    scopus 로고
    • Germline stem cell gene PIWIL2 mediates DNA repair through relaxation of chromatin
    • doi:10.1371/journal.pone.0027154
    • Yin DT, Wang Q, Chen L, Liu MY, Han C, Yan Q, Shen R, He G, Duan W, Li JJ et al. 2011 Germline stem cell gene PIWIL2 mediates DNA repair through relaxation of chromatin. PLoS ONE 6 e27154. (doi:10.1371/journal.pone.0027154)
    • (2011) PLoS ONE , vol.6
    • Yin, D.T.1    Wang, Q.2    Chen, L.3    Liu, M.Y.4    Han, C.5    Yan, Q.6    Shen, R.7    He, G.8    Duan, W.9    Li, J.J.10
  • 44
    • 38849145619 scopus 로고    scopus 로고
    • Downregulation of Dkk3 activates β-catenin/TCF-4 signaling in lung cancer
    • doi:10.1093/carcin/bgm267
    • Yue W, Sun Q, Dacic S, Landreneau RJ, Siegfried JM, Yu J & Zhang L 2008 Downregulation of Dkk3 activates β-catenin/TCF-4 signaling in lung cancer. Carcinogenesis 29 84-92. (doi:10.1093/carcin/bgm267)
    • (2008) Carcinogenesis , vol.29 , pp. 84-92
    • Yue, W.1    Sun, Q.2    Dacic, S.3    Landreneau, R.J.4    Siegfried, J.M.5    Yu, J.6    Zhang, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.