β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

Gut

Volumn 61, Issue 9, 2012, Pages 1306-1314

  Smartt, Helena J M ^a   Greenhough, Alexander ^a   Ordóñez Morán, Paloma ^b   Talero, Elena ^c   Cherry, Catherine A ^a   Wallam, Catherine A ^a   Parry, Lee ^d   Al Kharusi, Manal ^a   Roberts, Heather R ^a   Mariadason, John M ^e   Clarke, Alan R ^d   Huelsken, Joerg ^c   Williams, Ann C ^a   Paraskeva, Chris ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b EPFL   (Switzerland)

^c UNIVERSITY OF SEVILLE   (Spain)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e AUSTIN HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; BETA CATENIN; CYCLOOXYGENASE 2 INHIBITOR; SMALL INTERFERING RNA; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CHROMATIN IMMUNOPRECIPITATION; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; COLORECTAL TUMOR; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; UPREGULATION;

ADENOMA; ANIMALS; BETA CATENIN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; DINOPROSTONE; DOWN-REGULATION; ENZYME REPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84864987488     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-300817     Document Type: Article

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