Liposomes coated with N-trimethyl chitosan to improve the absorption of harmine in vivo and in vitro

International Journal of Nanomedicine

Volumn 11, Issue , 2016, Pages 325-336

  Chen, Wei Liang ^a   Yuan, Zhi Qiang ^a   Liu, Yang ^a   Yang, Shu Di ^a   Zhang, Chun Ge ^a   Li, Ji Zhao ^a   Zhu, Wen Jing ^a   Li, Fang ^a   Zhou, Xiao Feng ^b,c   Lin, Yi Mei ^d   Zhang, Xue Nong ^a  

^a Unit of Biochemical Pharmacology and Protein Biotechnology   (China)

^b SOOCHOW UNIVERSITY   (China)

^c Changshu Hospital of Traditional Chinese Medicine   (China)

^d XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Caco 2 cell; Harmine; Liposomes; TMC

Indexed keywords

CHITOSAN; HARMINE; LIPOSOME; DRUG CARRIER; N-TRIMETHYL CHITOSAN CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG TRANSPORT; DRUG UPTAKE; ENZYME DEGRADATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; MOUSE; NEAR INFRARED IMAGING SYSTEM; NONHUMAN; RAT; SUSTAINED DRUG RELEASE; TIGHT JUNCTION; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; CACO-2 CELL LINE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GASTROINTESTINAL TRACT; HUMAN; METABOLISM; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELLS, CULTURED; CHITOSAN; DRUG CARRIERS; GASTROINTESTINAL TRACT; HARMINE; HUMANS; IN VITRO TECHNIQUES; LIPOSOMES; MICE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84955094624     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S95540     Document Type: Article

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