N-trimethyl chitosan nanoparticle-encapsulated lactosyl-norcantharidin for liver cancer therapy with high targeting efficacy

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 7, 2012, Pages 1172-1181

  Guan, Min ^a   Zhou, Yi ^a   Zhu, Qiao Ling ^a   Liu, Yang ^a   Bei, Yong Yan ^a   Zhang, Xue Nong ^a   Zhang, Qiang ^b  

^a SOOCHOW UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Lactosyl norcantharidin; Liver cancer; N trimethyl chitosan; Nanoparticles; Targeting efficacy

Indexed keywords

ANTI-TUMOR ACTIVITIES; AVERAGE PARTICLE SIZE; CELLULAR UPTAKE; CROSS-LINKAGE; DIALYSIS METHOD; ENTRAPMENT EFFICIENCY; HEPATOCARCINOMA; HEPG2 CELLS; HUMAN LIVER CANCER CELLS; IN-VITRO; IN-VIVO; LACTOSYL-NORCANTHARIDIN; LIVER CANCERS; MURINE MODEL; REALTIME IMAGING; SUSTAINED RELEASE; TARGETING EFFICACY;

CELL CULTURE; CELL DEATH; CHITOSAN; DIALYSIS; DRUG PRODUCTS; NANOPARTICLES;

SYNTHESIS (CHEMICAL);

CHITOSAN; LACTOSYL NORCANTHARIDIN; NANOPARTICLE; NORCANTHARIDIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DIALYSIS; DRUG EFFICACY; ENCAPSULATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; CARCINOMA, HEPATOCELLULAR; CHITOSAN; DRUG DELIVERY SYSTEMS; HEP G2 CELLS; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MICE; NANOPARTICLES;

MURINAE;

EID: 84866491971     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.01.009     Document Type: Article

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