Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer

Phytomedicine

Volumn 21, Issue 3, 2014, Pages 348-355

  Zhang, Hao ^a   Sun, Kun ^a   Ding, Jing ^b   Xu, Huae ^a   Zhu, Lingjun ^a   Zhang, Kai ^a   Li, Xiaolin ^a   Sun, Weihao ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cyclooxygenase 2; Gastric cancer; Harmine alcaloid; Invasion; Proliferation

Indexed keywords

CYCLINE; CYCLOOXYGENASE 2; GELATINASE A; HARMINE; PROTEIN BAX; PROTEIN BCL 2; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; PLANT EXTRACT; PTGS2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; IC 50; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER; TUMOR CELL; TUMOR GROWTH; TUMOR VOLUME; WOUND HEALING; ANIMAL; CELL MOTION; CHEMISTRY; DRUG EFFECTS; METABOLISM; NUDE MOUSE; PEGANUM; PHYTOTHERAPY; STOMACH; STOMACH NEOPLASMS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL MOVEMENT; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DOWN-REGULATION; HARMINE; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, NUDE; PEGANUM; PHYTOTHERAPY; PLANT EXTRACTS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-BCL-2; STOMACH; STOMACH NEOPLASMS;

EID: 84896492162     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.09.007     Document Type: Article

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