Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase

Nature

Volumn 529, Issue 7585, 2016, Pages 239-242

  Reimer, Janice M ^a   Aloise, Martin N ^a   Harrison, Paul M ^a   Martin Schmeing, T ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GRAMICIDIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDYL CARRIER PROTEIN; 4'-PHOSPHOPANTETHEINE; ANTIINFECTIVE AGENT; CARRIER PROTEIN; COENZYME; GRAMICIDIN-S-SYNTHETASE 2; ISOMERASE; MULTIENZYME COMPLEX; PANTETHEINE; PEPTIDE SYNTHASE; PROTEIN BINDING; TRANSFER RNA; TRANSFERASE;

ANTIBIOTICS; BIOCHEMISTRY; BIOLOGICAL PRODUCTION; CATALYSIS; CHEMICAL BINDING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PEPTIDE; PROTEIN; SUBSTRATE;

ADENYLATION; ARTICLE; BACTERIAL GENE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODIFICATION; CONVERGENT EVOLUTION; CRYSTAL STRUCTURE; FORMYLATION; HYDROGEN BOND; LGRA GENE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; TAILORING DOMAIN; ANALOGS AND DERIVATIVES; BIOCATALYSIS; BIOSYNTHESIS; BREVIBACILLUS; CARBOHYDRATE METABOLISM; CHEMICAL STRUCTURE; CHEMISTRY; COENZYME; ENZYME ACTIVE SITE; ENZYMOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID ISOMERASES; ANTI-BACTERIAL AGENTS; BINDING SITES; BIOCATALYSIS; BREVIBACILLUS; CARBOHYDRATE METABOLISM; CARRIER PROTEINS; CATALYTIC DOMAIN; COENZYMES; CRYSTALLOGRAPHY, X-RAY; GRAMICIDIN; HYDROXYMETHYL AND FORMYL TRANSFERASES; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; PANTETHEINE; PEPTIDE SYNTHASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA, TRANSFER;

EID: 84954513103     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16503     Document Type: Article

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