Elevated hepatic MIR-22-3p expression impairs gluconeogenesis by silencing the wnt-responsive transcription factor Tcf7

Diabetes

Volumn 64, Issue 11, 2015, Pages 3659-3669

  Kaur, Kirandeep ^a   Vig, Saurabh ^a,b   Srivastava, Rohit ^c   Mishra, Akansha ^c   Singh, Vijay Pal ^a   Srivastava, Arvind K ^c   Datta, Malabika ^a,b  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH   (India)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; GLUCOSE; INSULIN; MICRORNA 22; MICRORNA 22 3P; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR 7; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HNF1A PROTEIN, MOUSE; LIPID; MICRORNA; MIRN22 MICRORNA, MOUSE;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; DOWN REGULATION; GENE EXPRESSION; GENE SILENCING; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN SENSITIVITY; LIVER LEVEL; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN RNA BINDING; UPREGULATION; ANIMAL; BLOOD; GENETICS; INSULIN RESISTANCE; LIVER; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSIOLOGY;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; GLUCONEOGENESIS; HEP G2 CELLS; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; INSULIN; INSULIN RESISTANCE; LIPIDS; LIVER; MALE; MICE; MICRORNAS; UP-REGULATION;

EID: 84954390921     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-1924     Document Type: Article

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